Background : No ideal combination chemotherapy for lung cancer has been established even though lots of combination anticancer chemotherapies have been tried. For the combination of anticancer drugs, the interaction of anticancer drugs is very important but unpredictable factor. In this experiment, we designed and tested new experiment to measure the interaction of two anticancer drugs using MIT assay in an attempt to predict clinical response of the combination regimen. Methods : With human lung adenocarcinoma cell line (PC-14), the cytotoxic effect of cisplatin, adriamycin, mitomycin C and etoposide were measured by in vitro chemosensitivity test (MIT assay). The combined cytotoxic effects of combination of two drugs were also measured in every combination of the drug concentrations and analyzed the interaction by Anava analysis of two way factorial design. Results : Four individual drugs showed cytotoxic effects on PC-14 by dose dependent fashion. Comparison of two drug combinations revealed that mitomycin C + cisplatin and adriamycin + cisplatin combinations showed stronger synergistic cytotoxic effects. Conclusion : From this experiment, we suggest two combinations of mitomycin C + cisplatin and adriamycin + cisplatin as chemotherapeutic regimens for unresectable non-small cell lung cancer. Furthermore, this experimental design could be applied to other types of cancer requiring combination anticancer chemotherapy.
Journal of Korean Home Economics Education Association
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v.19
no.1
s.43
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pp.149-162
/
2007
Fashion industry that is apparel of the latest textile industry become the center and it is universal inclination that addend value of design is high more and our country apparel industry is accelerating change by life culture industry of the high added value center. Differentiation of goods, high added value anger can be required by activation of professional manpower for strengthening competitiveness of domestic apparel field, and it is design to be texture another thing can raise this. Specific education to train able member of society based on these actual conditions grasping society actual conditions in present age that is specialized and diversifies and atomizes should be achieved. Hereupon, we have researched over current education status about domestic textile related courses and come to a conclusion described below. Domestic textile related courses are offering mostly in weaving and staining as major subjects, therefore distinguished character of each university can not be found. However, in comparison of importance between theoretical courses and practical courses, theoretical courses are gradually considered more importantly And the number of courses about commodity and operation is steadily increasing compared to those of design element. Nevertheless, for the concept of creativity as design education ever been pursuing by experiment and practice, we are also required to keep close relationship with industry as well as making efforts to reduce differences between college education and practical business. In addition, textile related colleges also need to be armed with more professional knowledge in odor to provide their students not only with more job opportunities but also with chances for self-development.
Journal of the Korean Society of Clothing and Textiles
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v.31
no.6
s.165
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pp.892-901
/
2007
This research is the initial step for establishing a convertible body sizing table applicable to the Korean and American female apparel industry. All 3D female measurement data of the two countries were obtained from Size Korea Project and SizeUSA Project. The sample subjects used in this study were 1,988 Korean and 6,306 American females. Thirty-four(34) variables were chosen as the principal measurements in making garments. The conclusion of this research was as follow: First, it was determined that American women were larger and longer than Korean women in all measurement except shoulder slope measurement. Second, according to the differences analysis of the each age group in Korean Females, all measurements except hip girth had significant differences among the age groups. In case of American females, all measurements except arm length(shoulder to wrist) had significant differences among the age groups. Third, in the comparison of differences between the age groups of the two countries' women, some dimensions varied significantly with age, while others did not show any statistical significance among the age groups. Fourth, according to the t-tests of same age groups between Korean & American female measurements, American female measurements were larger and longer than Korean in all measurements except crotch length total, shoulder slope, hip girth-bust girth and hip girth-waist girth.
Kim, Yang-Jin;Michelman, Susan;Seock, Yoo-Kyoung;Lee, Soo-Kyoung
Journal of the Korean Society of Clothing and Textiles
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v.32
no.6
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pp.918-927
/
2008
The purpose of this research was to identify the dimensions of modesty and immodesty in dress and to examine the differences in female college students' perceptions, in various cultures, of modest and immodest clothes. The researchers selected South Korea and the United States for the cross-cultural comparison study because these two countries show distinctive cultural characteristics. This study was conducted through both qualitative and quantitative methods. According to the result of the preliminary study, 47 questions were developed. The 4 Likert type scales used in the questionnaire were written in both English and Korean. Pretests were performed simultaneously in both countries. 174 American and 208 Korean students completed the questionnaire. The data were analyzed using SPSS. According to the results of factor analysis, there were 4 factors identified for the modesty-immodesty concept, including 'Conservativeness', 'Body exposure', 'Social appropriateness', and 'Attracting attention from others'. Students answered that they liked to wear conservative and socially appropriate dress in both cultures and that they did not like to wear clothing which draws a great deal of attention to them. Cultural differences were also identified. Based on the results, American students dressed more conservatively than Korean students, while Korean students preferred to wear revealing dress. American students were more conservative and preferred modest clothing. Also Korean students were more open about their body exposure and had immodest clothing attitudes.
Until the early part of the 1990s, interior design has never been thought important by car makers. Repeated attempts have been made to systemize a technical structure, such as layout, driving method, and size, and the car's interior design has been developed by in simple comparison with the exterior design. In the 1990s, however, this trend began to change because consumers began spending more time in their cars, so the motive of the technology development became that of giving comfort and functional satisfaction to the customers. Observing how a person spends inside his or her car and considering the latest trends in car interiors have made a consumer-oriented sense of value i.e., intensifying the personality of the car's interior design and considering the emotional makeup of the consumer factor in the acquisition of a strategic brand identity. These days, car interiors assume a new concept every year due to the constant change in various factors, and the application of a high-tech design, with a sensing function and a navigation system, to achieve driverless running, is being raised as a key trend element technology for the future. Now, at the present when multilateral concept applications of design are attempted under the direct influences from other fields such as product design, fashion and furniture, I would like to lay stress on investigating and analysing the changes in car interior design varying with the background of the times and formative characteristics from the object point of view. On this study, I would like to compare the background of the times and flow of car interior design with priority given to crash pad and would like to attempt to present the direction of the future car interior design together with diversifying major technical factors.
Journal of the Korea Society of Computer and Information
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v.27
no.4
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pp.79-88
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2022
In order to develop a bodice prototype suitable for obese women in their 20s, this study compared and analyzed a total of five pattern system methods, including prototype of France and Japan, one prototype for education in Korea and two prototype for industries in Korea. Through this, this study attempted to investigate the bodice pattern system suitable for the development of plus-size women's clothing. For the pattern drafting, pattern 1 was applied with the most body dimensions such as interscye fold front, interscye fold back, bust circumference, neck circumference, and waist back length, and pattern 2, pattern 4, and pattern 5 were made based on bust circumference and waist back length. As a result of the appearance evaluation, Pattern 3 was evaluated as the best pattern in all items except for the suitability of the center front length and the suitability of the side waist circumference position. However, it was evaluated as inappropriate in items such as the vertical side line, the suitability of the side waist circumference line position, the suitability of interscye fold back position and shape, and the suitability of the back shoulder dart position. Most of the pattern drafting methods are based on the size of the bust circumference, but other institutional methods are considered necessary when setting the neck circumference and shoulder length for 20s obesity women. In addition, it is also required to develop a method for setting the front center length due to abdominal protrusion.
Journal of the Institute of Electronics and Information Engineers
/
v.50
no.11
/
pp.12-20
/
2013
Even though extensive research results have been applied to wireless cellular systems to improve their capacity and coverage, severe performance degradation experienced in cell boundary areas still remains as a major limiting factor to prohibit further improvement of user equipment (UE) throughput. In the Long Term Evolution-Advanced (LTE-A) standard of the Third Generation Partnership Project (3GPP), Some advanced techniques have been introduced to overcome this "cell-edge problem", including coordinated multipoint transmission and reception (CoMP) and inter-cell interference coordination (ICIC). In this paper, we propose yet another strategy to improve the performance of low-tier UEs by using the concept of multiple beam direction patterns (BDPs). Such multiple BDPs can be implemented using multi-layer antenna arrays stacked vertically at base station (BS) sites to transmit signals in different main beam directions. In comparison to conventional three-sector antennas with a fixed beam pattern, the proposed methods makes signal transmission in a rotational fashion to significantly enhance the reception quality of UEs located near sector (or cell) edge areas, preventing the situation where certain UEs are marginally covered by the BS for the whole transmission time. Performance evaluation results show that the proposed scheme outperforms the conventional three-sector transmission by 171% in low 5% UEs in terms of the UE throughput.
Component-based software development (CBD) technology has been widely accepted as a new effective paradigm for building software systems with reusable components, consequently reducing efforts and shortening time-to-market. Hence, components should provide standard or common functionalities in a domain, yielding a higher level of reusability. Especially, micro-level variability within the commonality should also be modeled so that a product member-specific business logic or requirement can be supported through component tailoring or customization The importance of commonality and variability (C&V) analysis has been emphasized in several CBD methods, but they lack of well-defined systematic process, detailed instructions, and standard artifact templates. As the result, the development of components has been carried out in ad-hoc fashion, depending on developer's experience. In this paper, we propose a systematic process and work instructions to design components. The process consists of phases and their activities and each activity is specified with detailed instructions and artifact templates in order to facilitate effective development of components. To verify a feasibility of the propose method, a case study in a banking domain and comparison and assessment between the proposed method and other methods are additionally provided. With proposed processes and instructions, reusability and efficiency of developing components can be better supported.
Mobile Ad hoc NETworks (MANET) consist of mobile nodes which are usually powered by battery Approaches for minimizing power consumption have been proposed for all network layers and devices. IEEE 802.11 DCF (Distributed Coordination Function), a well-known medium access control protocol for MANETS, also defines a power save mode operation. The nodes in power save mode periodically repeat the awake state and the doze state in synchronized fashion. When all nodes are in the awake state, the exchange the announcements for the subsequent message transmission with neighbors. The nodes that send or receive the announcements stay awake for data transmission, and others go into the dole state. The previous works for enhancing the power save mode operation have focused on shortening the duration of the awake state. We observed that the longer sleeping period results in seriously long delivery latency and the consequent unnecessary power consumption as well, because the packets can move forward only one hop for a fixed interval. In this paper, we propose an improved protocol for the power save mode of IEEE 802.11 DCF, which allows the flooding packets to be forwarded several hops in a transmission period. Our approach does not reduce the duration of compulsory awake period, but maximizes its utilization. Each node propagates the announcements for next flooding to nodes of several hops away, thus the packets can travel multiple hops during one interval. Simulation results of comparison between our scheme and the standard show a reduction in flooding delay maximum 80%, and the unicasting latency with accompanying flooding flows near 50%, with slight increase of energy consumption.
Journal of Korean Home Economics Education Association
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v.33
no.3
/
pp.129-142
/
2021
The purpose of this study was to provide educational data on teaching clothing culture by examining the effects of clothing lifestyle on attitudes toward teachers' clothing for 270 secondary school pre-service teachers. For data analysis, factor analysis, Cronbach's α reliability coefficients, t-tests, one-way analysis of variance, Duncan's multiple comparison verification, and multiple regression analysis were performed using SPSS 24.0 program. As a result of the study, first, the clothing lifestyle of secondary school pre-service teachers was classified as fashion trend orientation, clothing importance orientation, attractive appearance orientation, and economic orientation factors. In addition, the attitude toward teacher's clothes was classified into activity, fashionability, and modesty factors. Second, there was a statistically significant difference in the attitudes toward clothing lifestyle and teacher clothing of secondary school pre-service teachers according to gender and year in college, which are demographic variables. Third, it was found that the clothing lifestyle of secondary school pre-service teachers, who are Generation Z, had an effect on the attitude toward teacher clothes. In conclusion, this study proposes that school administrators and teachers should depart from the former stereotypes about teacher clothes and to encourage a culture in which teachers can dress and perform their role of teaching according to individual's changing lifestyles.
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