• The Korea Journal of Herbology
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• v.28 no.2
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• pp.33-38
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• 2013

Objects : Apoptosis leads to the death of a cell. The mitochondrial pathway of apoptosis, a process regulated by the Bcl-2 family of proteins, plays a key role in various biological processes. The tuber of Liriope platyphylla Wang et TANG (Liliaceae), also known as Liriopis tuber, is famous in Oriental medicine owing to its tonic, antitussive, expectorant and anti-asthmatic properties. The purpose of this study was to observe the effect of the Liriopis tuber on mitochondrial-mediated apoptosis in PC-12 cells. Method : A cytotoxic test on Liriopis Tuber water extract was conducted and another MTT assay was conducted to observe the cytoprotective effect against 4-HNE 25 ${\mu}M$ that causes oxidative stress in PC-12 cells for 24 hours. In addition, in order to observe the expression of Bcl-2 and Bax protein involved with apoptosis, western blot was conducted. Results : The LT water extract had no toxicity for PC-12 cell. In the cytoprotective effect against 4-HNE, both of the group treated with 50 ${\mu}g/m{\ell}$ and 100 ${\mu}g/m{\ell}$ of LT water extract showed a significant increase in comparison with the control group. In Bax protein expression, all the experimental groups treated with LT water extract showed a decrease in comparison with the control group but had no significance. In Bcl-2 protein expression, all the experimental groups treated with LT water extract showed a significant increase in comparison with the control group. Conclusion : These results suggest that LT is effective in reducing apoptosis.

• The Korean Journal of Applied Statistics
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• v.10 no.2
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• pp.353-366
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• 1997

In this paper, we derive an approximate optimal Bayes group sequential design for a given loss function. We use the Monte-Carlo method to compare the ASN(average sample size) function and Bayes risk of approximate optimal Bayes group sequential design, Pocock design and O'Brien and Fleming design. Also introduced is the concept of Bayes efficiency and percentage loss of information due to grouping for the group sequential design and use it to measure the loss of information for different group sizes.

• Education of Primary School Mathematics
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• v.21 no.4
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• pp.445-459
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• 2018

The purpose of this study is to provide a method to help elementary school students learn ratio-related concepts effectively through visual representations. This study was conducted to identify the differences in the composition of ratio-related concepts between Korean and Singaporean textbooks, reconstruct a unit of proportional expressions and distributions by using visual representations and confirm the differences in performance between an experimental and a comparison group of 6th grade students. While the experimental group mathematics lessons is from the reconstructed textbook, the comparison group lessons is from an existing textbook that does not include any reconstructive representations. A t-test of mean was applied to determine the differences between the experimental and comparison group. Analysis revealed significant differences in the mean between the experimental group and the comparison group, and the intermediate level group showed more improvement compared to the higher and lower level groups. An implication of this study is that the application of visual representations can assist students' understanding of ratio-related concepts.

• Journal of the Korean Geosynthetics Society
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• v.17 no.4
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• pp.41-52
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• 2018

Since the composite ground design method is easy to apply for calculation or numerical analysis, it is applied to the design of cement mixing methods. However, the comparison studies between analysis and actual results such as a trial test and construction for the cement mixing method are few because the composite ground design method was developed for the compaction pile (SCP, GCP) methods. In this study, the results of various analysis methods, such as the composite ground analysis method (1 case) and the individual pile method (3 cases), were compared with actual measurements through a two-dimensional finite element numerical analysis. In case of the surface settlements, the results of study show that the individual plate method was larger than the actual measurements, while other methods are similar. The settlements at the under ground of the improved area is overestimated in all analysis methods. When comparing numerical analysis results for the horizontal displacement, and ground reaction forces, the individual pile method in equivalent wall concept was found to be the most similar to the measurements. The composite ground method was not able to predict the behavior of stress transfer (Arching effect) and it turned out that the prediction of horizontal displacement was too large.

• The Journal of Korean Medicine
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• v.31 no.5
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• pp.41-59
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• 2010

Objective: Headache is one of the most common symptoms in primary medical care. The purpose of this study was to support medical treatment by consideration of a new CTTH (chronic tension-type headache) oriental medical diagnosis index. Methods: An Oriental medical diagnosis questionnaire was administered to a CTTH group, migraine group and normal group. The result was classified by using LDA, CART, factor diagnosis and tested in comparison with the original diagnosis. Also, weighting method based on expert opinions was done. Results: 1. The result analyzed by using LDA has an accuracy of 93.9% in comparison with the original diagnosis. 2. High accuracy showed when the test was performed with about 35 significant questions and four questions selected based on SPSS Wilks' lambda. 3. There was accuracy of 90.9% when differentiation was performed by using CART compared with original diagnosis. 4. 10 factors has a high initial value after factor analysis, consisting of questions to the similar differentiation. 5. Diagnosis formula of headache was made by using weighting method based on expert opinions. Conclusion: Oriental medical diagnosis questionnaires make it possible to classify headaches significantly. The study about weighting method of CTTH can make it possible to classify symptoms more accurately.

• Journal of the Korea Safety Management & Science
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• v.13 no.3
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• pp.55-61
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• 2011

Unit cost for asbestos removal work which have been made out at government contract award for recent three years has been reviewed and shown with table. And the cost have been compared with ones made out by two agencies, American asbestos removal specialists, government ministry for making out comparison tables. First, legal and practical work status survey have been made to determine reasonability of introducing separate contract-awarding system, as a part of ensuring reasonable unit work cost. And then, two different status have been compared and there in introduction possibility of separate contract-awarding system, it is found out. In interior removal work case, it is thought that 50% by owner, 60% unit work cost by the expert of which removal specialist think as reasonable unit cost. the results for exterior and spray work method are shown with almost same context. Impact factors for determining unit work cost such as project mount, project kind, contract-awarding method, subcontract method have been compared with parties. Removal specialist and expert group have almost same ideas for project amount which has been hightestly weighed but owner's recognition has partially lower than specialists idea. There are almost no difference of recognition between three(3) parties for project kind. Idea comparison of reasonable unit work cost for asbestos removal work between three concerned parties has been analyzed and found out that expert group do unit work cost, 65% of which removal specialists estimate, in interior tex removal. And there is almost no difference between them in exterior roof slate removal. But there is considerable difference between them that owner estimates 50% unit cost of specialist one while expert group estimate 50% of specialist idea of unit removal cost.

• Journal of Technologic Dentistry
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• v.42 no.4
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• pp.334-340
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• 2020

Purpose: This study aimed to compare three-dimensional adaptation with the rinsing time of the temporary crown produced using the digital light processing method. Methods: The maxillary right first molar abutment was scanned with a dental scanner. A temporary crown was designed with the scanned abutment. The designed crown was made of 10 temporary crowns using a digital light processing printer. The crowns were divided into the 5-minute and 10-minute rinsing groups; 5 temporary crown washes were performed for each group. In order to obtain the internal data, each group was scanned for a temporary crown. The three-dimensional fit was measured by superimposing the scanned internal surface data and the abutment data. The average comparison of three-dimensional adaptation was analyzed using the Mann-Whitney U test. Results: The 5-minute rinsing group showed a significantly higher adaptation of 71.42±3.08 ㎛ as compared to the 10-minute rinsing group (67.52±0.92 ㎛) (p<0.05). Conclusion: When making a temporary crown with a digital light processing method, a rinsing time of 10 minutes is appropriate.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.203-211
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• 2021

Purpose : It was to compare changes in respiratory function (pulmonary function, inspiratory function) after four weeks of inspiratory muscle strengthening training (diaphragmatic breathing with upper arm exercise, Power-Breathe breathing) for 36 healthy people. Methods : Subjects were randomly assigned to diaphragmatic breathing with upper arm exercise (Group I) and Power-breathe breathing (Group II) was conducted by the protocol for four weeks five times per week. As the main measurement method for comparison between groups For pulmonary function, Forced Vital Capacity (FVC) and Forced Expiratory Volume at One second (FEV1) were used, and for inspiratory function, Maximum Inspiratory Capacity (MIC), Maximum Inspiratory Pressure (MIP), and Maximum Inspiratory Flow Rate (MIFR) were used. Results : In changes in pulmonary function between groups, FVC and FEV₁ showed no significant difference, and in inspiratory function changes, MIC showed no significant difference, but in MIP and MIFR, Group B significantly improved over Group A. Conclusion : The progressive resistance training using the Power-breath device applied to the inspiratory muscle did not show a significant difference in the increase in the amount of air in the lungs and chest cage compared to the diaphragmatic breathing training accompanied by the upper arm exercise. However, by increasing the air inflow rate and pressure, it showed a more excellent effect on improving respiratory function.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.167-172
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• 2005

This paper introduces a method which improves the performance of the identification of splice sites in the genomic DNA sequence of eukaryotes. This method combines a low order Markov model in series with a neural network for the predictions of splice sites. The lower order Markov model incorporates the biological knowledge surrounding the splice sites as probabilistic parameters. The Neural network takes the Markov encoded parameters as the inputs and produces the prediction. Two types of neural networks are used for the comparison. This method reduces the computational complexity and shows encouraging accuracy in the predictions of splice sites when applied to several standard splice site dataset.

• Journal of Life Science
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• v.18 no.7
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• pp.986-991
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• 2008

The purpose of this study was to investigate the effect of Taekwondo and calcium intake on physique, growth hormone and IGF-1 in elementary school male students. 24 subjects who the fourth grade and Taekwondo black belt ($1{\sim}2$ poom) were classified into three groups; Taekwodo +calcium intake group (8), Taekwondo group (8) and control group (8). The period of Taekwondo was 12 weeks, 5 times a week and each time 50 minutes with RPE ($7{\sim}15$) for intensity were treated and subjects were given calcium at 750 mg of pill after dinner a day during the 12 weeks. The conclusions of this study are as follows; In the comparison within each group, three groups all significantly increased in body height but in the comparison between groups, A and B groups were more significantly increased in body height than C. C significantly decreased in growth hormone and in the comparison between groups, A and B groups were more significantly increased in growth hormone than C. In the comparison within each group, A and B significantly increased in IGF-1 and in the comparison between groups, A and B groups were more significantly increased in IGF-1 than C. It is considered that Taekwondo and calcium intake give effects to body height by increasing growth hormone and IGF-1. It is necessary to continue the study, because the study results of growth hormone and IGF-1 are various by training method, intensity, nutrition.