Kim, Jin-Kyu;Shin, Hae-Shick;Lee, Young-Yup;Lee, Jin-Hong
Korean Journal of Environmental Biology
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v.25
no.3
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pp.191-196
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2007
Indoor air differs from outdoor atmosphere since it contains chemical and physical contaminants from building materials. This study deals with the biological effects of volatile organic compounds (VOCs) released from synthetic fiber carpet materials. One group of Tradescantia inflorescence was exposed to VOCs from the carpet sample in the environmental test chamber, while the other inflorescence group was exposed to a TO-14 standard gas mixture (1 ppm) for comparison. After the exposure, VOCs from the carpet were analysed by the desorber/GC/MS method, and micronuclei in the pollen mother cells of Tradescantia were scored under a microscope $({\times}400)$ to evaluate the genotocixicity induced by the exposure to VOCs. The chemical analysis confirmed that a total of 12 VOCs were released from the carpet materials, among which stylene $(71.9{\mu}g\;m^{-3})$ and toluene $(49.6{\mu}g\;m^{-3})$ were in the highest concentration. Twenty four hours of exposure to VOCs from the carpet in the environmental test chamber resulted in a micronucleus frequency as high as $7.73{\pm}0.75MCN$ per 100 tetrads, which was similar to that induced after exposure to the TO-14 standard gas mixture (1 ppm) for 4 hours. Meanwhile, two hours of exposure to the standard gas mixture did not cause a significant increase in the genotoxicity compared to the spontaneous micronucleus frequency. This result indicates that exposure for a long time to the air contaminated with VOCs from the carpet materials causes a genotoxic effect. The biological-chemical combination analyses in the study proved to be an effective tool for monitoring the indoor air contaminants.
Researchers of microarray experiment transpose processed images of raw data to possible data of statistical analysis: it is preprocessing. Preprocessing of microarray has image filtering, imputation and normalization. There have been studied about several different methods of normalization and imputation, but there was not further study on the order of the procedures. We have no further study about which things put first on our procedure between normalization and imputation. This study is about the identification of differentially expressed genes(DEG) on the order of the preprocessing steps using two-dye cDNA microarray in colon cancer and gastric cancer. That is, we check for compare which combination of imputation and normalization steps can detect the DEG. We used imputation methods(K-nearly neighbor, Baysian principle comparison analysis) and normalization methods(global, within-print tip group, variance stabilization). Therefore, preprocessing steps have 12 methods. We identified concordance measure of DEG using the datasets to which the 12 different preprocessing orders were applied. When we applied preprocessing using variance stabilization of normalization method, there was a little variance in a sensitive way for detecting DEG.
The flash point is one of the most important physical properties used to determine the potential for fire and explosion hazards of flammable liquids. Despite the needs of the experimental flash point data for the design and construction of chemical plants, there is often a significant gap between the demands for the data and their availability. This study have built and compared two models of partial least squares(PLS) and support vector machine(SVM) to predict the experimental flash points of 893 organic compounds out of DIPPR 801. As the independent variables of the models, 65 functional groups were chosen based on the group contribution method that was oriented from the assumption that each fragment of a molecule contributes a certain amount to the value of its physical property, and the logarithm of molecular weight was added. The prediction errors calculated from cross-validation were employed to determine the optimal parameters of two models. And, an optimization technique should be used to get three parameters of SVM model. This work adopted particle swarm optimization that is one of heuristic optimization methods. As the selection of training data can affect the prediction performance, 100 data sets of randomly selected data were generated and tested. The PLS and SVM results of the average absolute errors for the whole data range from 13.86 K to 14.55 K and 7.44 K to 10.26 K, respectively, indicating that the predictive ability of the SVM is much superior than PLS.
The purpose of this study is to analyze the effect of the glass ceiling induction factors on the improvement of the job Commitment on the glass ceiling perception and to analyze the effect of the organizational Commitment on the influence of the local medical institute and private medical institute employees. Purpose. As a research method, structural equation model analysis was carried out to investigate the influence relationship of each factor. In particular, multiple group analysis was performed to analyze the difference of influence relations between public and private medical personnel. Respectively. Result, First, empirical studies on the effect of the glass ceiling inducing factors on job Commitment showed that job Commitment was influenced by stereotype and organizational culture, and the magnitude of the influence was different. Second, the employees of the room medical center were influenced by perceived promotion, job placement, education and training, reward, and job satisfaction. Third, in the hypothesis that job Commitment will be affected by the perception of glass ceiling, only the workers of the private medical center showed significant results. Based on the results of this study, it will be necessary to plan policies to improve the perception of the glass ceiling phenomenon and improve its status in order to improve the personnel and system that women workers in the medical field can enter more senior management positions.
Journal of the Korean Academy of Child and Adolescent Psychiatry
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v.5
no.1
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pp.118-132
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1994
The purpose of this study was to compare communication and mother-child interactions of reactive attachment disordered children with normal children. The subjects were 24 children and their mothers participated in this study'12 reactive attachment disordered children and mothers, 12 normal children and mothers. The mother and her child were brought into a p]lay room and the mother was instructed to play with her child as she normally would at home. The play situations were videotaped. Tapes were transcribed and transcribed data was analyzed with 13 mutually exclusive categories encompassing pragmatic functions represented in communication form the early stage of multiword speech in childhood. The tapes were analyzed with 10 behavioral mother-child interaction patterns. As the statistical method, t-test and correlation was calculated. The results of this study were as follows : 1) Reactive attachment disordered children used significantly fewer 'filler', 'information', 'requests', 'describes' and 'disscus self'. 2) Reactive attachment disordered children's mother used significantly fewer 'filler' and 'names'. 3) Reactive attachment disordered children used significantly more 'independent play', fewer 'intiates interaction', 'responsiveness' and 'answer' Reactive attachment disordered children's mother used more 'control play', 'observe' and fewer 'initiates interaction'. 4) Children's communication patterns were related lo mother·'s communication and mother-child interaction types. Children's 'filler', 'information requests', 'describes' and 'disscus self' were consistantly related to mother's 'filler' and 'names', (Children's 'filler', 'information requests', 'describes'. 'disscus self' and mother-child's intiates interaction 'responsivness' were significantly positively correlationed and 'independant play', 'control play', 'observation' were significantly negatively correlationed. The results of reveal that communication and mother-child interaction pattern of reactive attachment disordered group was different from normal group and children's communication pattern were influenced by mother's communication and interaction patterns.
Kim, Chong-Hyun;Park, Young-Bum;Kim, Sung-Tae;Lee, Keun-Woo
The Journal of Korean Academy of Prosthodontics
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v.49
no.2
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pp.152-160
/
2011
Purpose: The aim of this study was to evaluate the volumetric change of teeth after preparation for various designs and margin locations through Micro CT analysis (Skyscan 1076: SKYSCAN, Konitch, Belgium). Materials and methods: The 36 artificial teeth were used to determine reduction volume of upper central incisor. According to the restorative design these 36 teeth were divided into 4 groups and according to the marginal location each group was divided into 3 subgroups. The volume of unprepared teeth was obtained by using Micro CT and the volume of prepared teeth was obtained in the same method. The CT scanned images before and after preparation were superimposed. Results: The volume difference was significantly increased as follows: traditional laminate veneer < full laminate veneer < all ceramic crown < metal ceramic crown. One-way ANOVA and Tukey multiple comparison analyses were used to analyze the data in this study. In each group the volume difference was significantly increased as follows: 1 mm above CEJ < CEJ < 1 mm below CEJ (P<.05). The % volume difference of all ceramic crown and metal ceramic crown was 31 - 48% and that of laminate veneer was 14 - 30%. The volume difference of the traditional laminate veneer was 1/3 of that of metal ceramic crown. The full laminate (1 mm below CEJ) and all ceramic crown (1 mm above CEJ) showed a similar volume difference. Metal ceramic crown showed 13.7% more volume difference than all ceramic crown. Conclusion: There exists the difference in volumetric change according to designs of restoration and margin locations of preparation.
Kim, Kyung-Hwa;Kim, Kyu-Han;Lee, Sun-Kil;Hur, Myung;Kim, Yong-Jin
Journal of Gifted/Talented Education
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v.15
no.1
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pp.67-84
/
2005
In this study we investigated the adequacy of tools for distinction gifted students through the comparison these mutual relation on the basis of data, like paper test, the depths interview score, and the rest data((TTCT: Torrance Tests of Creative Thinking, IQ test, FASP: Find A Shape Puzzle, V.T: Visualization Tests and Exp: experimental ability test), and analysis data of EEG test for examining the adequacy of tools for identification gifted students. So, we developed Brain Wave gifted Index(G-Index) for finding another distinction ability as using brain waves data. The standard of index development use gifted brain characteristic in closed-eyes rest state which is judged like that characteristic of distinction between gifted and normal students is the most clear and consistence. That is, the degree of unified pattern between each object and gifted PCA pattern was defined by Pearson method which added spatial mutual index to weight concept. This refer to mean number of spatial PCA pattern. Searching for the possibility of distinction gifted gave distinction effect in 76%. The result of regression analysis on the basis of mutual relation between the rest data is . The probability formula for distinct gifted group is as follow. $$P=\frac 1{1+e^{-[-0.018(TTCT)+0.057(IQ)+1.916(FASP)+0.682(V.T)+0.088(Exp.)+0.034(G-Index)-57.510]}}$$ The result of this calculation showed that probability for distinct in gifted group was very good(95.0%). On the basis of upper result, tools for identification gifted students should be estimated as using many-sided estimation data whatever possible. And following study about development, and operation of tools for distinction suitable to gifted student in science should be progressed.
Even though clinical use DRE, PSA and TRUS for screening while diagnosing prostate cancer early, however, we cannot achieve to diagnose it accurately by one method. Thus, mutual supplements are strongly required in diagnosis. It means that we should identify relationship between prostate volume and serum PSA under different ages for better diagnosis. The subjects(405 men) visited the department of diagnostic radiology in a general university hospital from January 2008 to December 2008, who was going to take the prostatic evaluation by TRUS. 13 men, who did definite diagnosis of prostate cancer before through biopsy, were excluded in this study. All data were expressed as mean and standard deviations by using SPSS 14.0 package programs and were analyzed by using one-way ANOVA to evaluate the effect of different ages. And Scheffe Post hoc comparison is accomplished in order to make significant difference in prostate volume, PSA and PSAD according to ages. Pearson correlation was used for ages, prostate volume, PSA and PSAD. According to examination, the subjects' prostate volume and serum PSA level increase as person's age. We can see significant difference between group over 70 years and group from 40 and 50 years. Moreover, age, prostate volume and serum PSA have significant positive correlation. Even though we can get variations in serum PSA level by changing prostate volume according to ages, it is worthwhile to mention that more strong association for prostate volume is observed than ages in elevation of serum PSA. Therefore, it is strongly recommended to consider prostate volume weightly when it comes to evaluate for men with elevated PSA level. Finally, TRUS is an excellent extra equipment to diagnose prostate cancer because it can contribute to early diagnose and pertinent treatment of prostate cancer.
"Residual stress" can be developed during polymerization of the dental composite and it can be remained after this process was completed. The total amount of the force which applied to the composite restoration can be calculated by the sum of external and internal force. For the complete understanding of the restoration failure behavior. these two factors should be considered. In this experiment. I compared the residual stress of the recently developed nanofilled dental composite by ring slitting methods. The composites used in this study can be categorized in two groups. one is microhybrid type-Z250, as control group, and nanofilled type-Grandio, Filtek Supreme. Ceram-X, as experimental ones. Composite ring was made and marked two reference points on the surface. Then measure the change of the distance between these two points before and after ring slitting. From the distance change, average circumferential residual stress $({\sigma}{\theta})$ was calculated. In 10 minutes and 1 hour measurement groups, Filtek Supreme showed higher residual stress than Z250 and Ceram-X. In 24 hour group, Filtek showed higher stress than the other groups. Following the result of this experiment, nanofilled composite showed similar or higher residual stress than Z250, and when comparing the Z250 and Filtek Supreme, which have quite similar matrix components. Filtek Supreme groups showed higher residual stress.
Changes in components of onion vinegar during two-stage fermentation were investigated. One sample group (A) was prepared with onion juice by extraction and concentration (15 brix), and the other group (B) was prepared using the same method but supplemented with sucrose. Comparison of glucose (4.1%), fructose (4.2%), and sucrose (0.6%) found in A as major sugars with those (3.2, 3.3, and 4.6%, respectively) of B showed a significant difference in sucrose concentration. During alcohol fermentation, S. kluyvery DJ97 consumed these sugars completely. At 36 hr of alcohol fermentation, concentrations of reducing and total sugars decreased to 0.5 and 0.8%, in A, and 0.4 and 0.6%, in B, respectively. No further changes were detected in the concentrations of these sugars thereafter. From 12 hr of fermentation, alcohol concentrations in groups A and B increased markedly, maximizing at 7.0% at 36 hr A and at 8.2% at 48 hr in B, and finally decreased thereafter in both groups. The detected alcohol components were ethanol, acetaldehyde, methanol, n-propyl alcohol, iso-butanol, and iso-amyl acohol. During acetic acid fermentation, the concentration of acetic acid as the major organic also increased significantly in both groups (4,776.72 and 4,894.93 mg% in A amd B, respectively). Other organic acid contents such as malic and succinic acids were higher in A than B. these results indicate that vinegar is better produced in onion extract with no sucrose supplementation based on its organic acid contents.
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