• Journal of Microbiology and Biotechnology
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• v.24 no.1
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• pp.119-126
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• 2014

Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disorder that primarily affects the flexible joints and may also affect a number of tissues and organs. The progression of RA involves an inflammatory response of the capsule around the joint, swelling of synovial cells with excess synovial fluid (SF), and the development of fibrous tissue in the synovium. Since the progressive pathology of the disease often leads to the irreversible destruction of articular cartilage and ankylosis of the joint, early diagnosis of RA is essential. Thus, we undertook a comparative proteomic approach to investigate novel biomarkers for early diagnosis using SFs and serums from RA patients. As a result, we identified 32 differentially expressed spots in SFs and 34 spots in serums. The differential expression of the STEAP4 and ZNF 658 proteins were validated using immunoblotting of the SFs and serums, respectively. These data suggest that differentially expressed proteins in SFs and serums could be used as RA-specific biomarkers for the diagnosis and monitoring of RA. Furthermore, these findings advance our understanding of the molecular etiopathogenesis of RA.

• Journal of Korean Library and Information Science Society
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• v.48 no.2
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• pp.295-322
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• 2017

As a first step in developing a more effective and robust approach to faculty research performance assessment, this study analyzed the existing faculty research assessment methods by comparing Korean universities' research evaluation standards, National Research Foundation of Korea's (KRF) standard for assessing research proposals, and various bibliometric measures. The study data included research evaluation standards of KRF along with 27 Korean universities with Library and Information Science (LIS) department, and the publication data of 183 LIS faculties in Korean universities from 2001 to 2015, which consisted of 3,863 papers 16,978 citations. After the comparative analysis of research evaluation standards, the study examined the rankings of institutions and faculty produced by applying the collected standards and bibliometric metrics to the publication data. The study showed that Korean university standards for research evaluation, which aim to consider both productivity and impact of faculty research, differ from similar bibliometric measures such as h-index, and the difference could significantly impact the assessment of faculty research performance.

• The Journal of Society for e-Business Studies
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• v.27 no.1
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• pp.111-126
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• 2022

As the technology hegemony war between the United States and China develops and the importance of R&D increases, countries around the world are increasing their R&D investment. In Korea, the size of R&D investment by the government and companies has steadily increased every year, and cutting-edge technologies are being developed in various fields as it shifts to the direction of creative technology development. However, the number of cases in which high-tech core technologies in Korea, which have invested a lot of budget, time, and effort, are illegally leaked overseas is also steadily increasing. Research security is an activity to safely protect protected objects in the research environment from risk factors such as leakage and deodorization, and laws and systems for research security are being reorganized not only in Korea but also in the United States and other countries around the world. In this paper we aims to derive Korea's research security policy direction, focusing on US research security cases which ranks first in R&D expenses around the world to improve the R&D system and actively discusses R&D policies and laws.

• Journal of Microbiology and Biotechnology
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• v.33 no.11
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• pp.1428-1436
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• 2023

The three Gram-negative, catalase- and oxidase-positive bacterial strains RS43^T, HBC28, and HBC61^T, were isolated from fresh water and subjected to a polyphasic study. Comparison of 16S rRNA gene sequence initially indicated that strains RS43^T, HBC28, and HBC61^T were closely related to species of genus Curvibacter and shared the highest sequence similarity of 98.14%, 98.21%, and 98.76%, respectively, with Curvibacter gracilis 7-1^T. Phylogenetic analysis based on genome sequences placed all strains within the genus Curvibacter. The average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) values between the three strains and related type strains supported their recognition as two novel genospecies in the genus Curvibacter. Comparative genomic analysis revealed that the genus possessed an open pangenome. Based on KEGG BlastKOALA analyses, Curvibacter species have the potential to metabolize benzoate, phenylacetate, catechol, and salicylate, indicating their potential use in the elimination of these compounds from the water systems. The results of polyphasic characterization indicated that strain RS43^T and HBC61^T represent two novel species, for which the name Curvibacter microcysteis sp. nov. (type strain RS43^T =KCTC 92793^T=LMG 32714^T) and Curvibacter cyanobacteriorum sp. nov. (type strain HBC61^T =KCTC 92794^T=LMG 32713^T) are proposed.

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2007.11a
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• pp.49-57
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• 2007

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2003.04a
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• pp.124-124
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• 2003

• The Journal of the Korean dental association
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• v.39 no.8 s.387
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• pp.676-683
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• 2001

• Proceedings of the Korean Vacuum Society Conference
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• 2009.08a
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• pp.142-142
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• 2009

• Bulletin of the Korean Space Science Society
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• 2006.04a
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• pp.106-106
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• 2006

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2005.10a
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• pp.135-135
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• 2005