• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.127-137
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• 2007

Objects : This study was designed to determine origin-plants of 3 kinds of Scrophulariaceae herbs reported worldwide 220 families 3000 species, domestic 21 families 55 species by researching efficacy of each herb. Furthermore the objects of study were confirmation of genuine species and substitution species standing on the results. Methods : In this studies, the origin-plants and efficacy were determined by bibliographic method. Results : The results indicate that 1. There were total 15 species of original plants of Scrophulariaceae herbs, 9 species for Radix Scrophulariae, 4 species for Radix Rehmanniae Recens, 2 species for Rhizoma Picrorrhizae. 2. In the view of authenticity of Radix Scrophulariae, there were 2 genuine species, 1 species for substitution, and study of 6 species later on. 3. In the view of authenticity of Radix Rehmanniae Recens, there were 2 genuine species, 1 species for substitution, and study of 1 species later on. 4. In the view of authenticity of Rhizoma Picrorrhizae, all the original species was genuine species. 5. The each efficacy of origin-plants were reported in the main subject. Conclusions : The 15 original plants were present among the 3 medicinal herbs in the common family scrophul ariaceae. There were 2 genuine species in Radix Scrophulariae and Rhizoma Picrorrhizae. All the original species was genuine species in Rhizoma Picrorrhizae.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.3
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• pp.46-56
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• 2011

Objectives: The purpose of this study is to find a way to apply current oriental pediatrics treatment guidelines based on a pediatric herb chapter in Dong-eui-bo-gam. Methods: We classified herbs based on the four properties, five flavors, attributive channel, a dosage form of the medicine, diagnosis, toxicity and character. Results & Conclusions: The result of this study is that there were lots of things that we have to learn - characteristics of common herbs in pediatrics and pediatric diseases and pathology. From this study, we also learn about changes of pediatric physiology and pathology. More related studies can be helpful for updating the current oriental pediatric guidelines.

• Korean Journal of Oriental Medicine
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• v.11 no.1
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• pp.1-18
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• 2005

As a result of study on the names of local medicinal herbs which described in Chobu (Chapter of Grass) of Korean medical book Bonchojeonghwa, we came to the following conclusions. 1) Compared with the existing domestic medical books' local medicinal herb names, those of Donguibogam had the closest relationship with Bonchojeonghwa. Out of local medicinal herb names described in Chobu of Bonchojeonghwa, a third is only shown in Bonchojeonghwa, and another third is same as those in Donguibogam. 2) The notation of local medicinal herb names in Bonchojeonghwa is not so consistent as Donguibogam. In Bonchojeonghwa, we can see many examples of inconsistent notations over the same thing. Moreover, there are some examples, which are suspected to be an expression of dialect. 3) In spite of close similarity between the names of local medicinal herbs in Bonchojeonghwa and Donguibogam, the author of Bonchojeonghwa doesn't seem to directly refer to or quote Donguibogam, because it doesn’t make sense that the author of Bonchojeonghwa intentionally referred to regular, consistent Donguibogam in irregular, inconsistent way. 4) In spite of very low possibility of direct reference or quotation among Bonchojeonghwa, Donguibogam and Bangyakhappyon, there are many examples of common format in its notation way on local medicinal herbs, which cannot be explained only as coincidence. And it tells us that there must be another publication which had been referred to or quoted by the said three medical books. 5) From the fact that there are a lot of examples of local medicinal herb names which doesn't show palatalization, or labialization, the names of local medicinal herbs described in Bonchojeonghwa must be the expression around 17th century.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.10
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• pp.1515-1521
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• 2016

Anethole and garlic have an immune modulatory effects on avian coccidiosis, and these effects are correlated with gene expression changes in intestinal epithelial lymphocytes (IELs). In this study, we integrated gene expression datasets from two independent experiments and investigated gene expression profile changes by anethole and garlic respectively, and identified gene expression signatures, which are common targets of these herbs as they might be used for the evaluation of the effect of plant herbs on immunity toward avian coccidiosis. We identified 4,382 and 371 genes, which were differentially expressed in IELs of chickens supplemented with garlic and anethole respectively. The gene ontology (GO) term of differentially expressed genes (DEGs) from garlic treatment resulted in the biological processes (BPs) related to proteolysis, e.g., "modification-dependent protein catabolic process", "proteolysis involved in cellular protein catabolic process", "cellular protein catabolic process", "protein catabolic process", and "ubiquitin-dependent protein catabolic process". In GO analysis, one BP term, "Proteolysis", was obtained. Among DEGs, 300 genes were differentially regulated in response to both garlic and anethole, and 234 and 59 genes were either up- or down-regulated in supplementation with both herbs. Pathway analysis resulted in enrichment of the pathways related to digestion such as "Starch and sucrose metabolism" and "Insulin signaling pathway". Taken together, the results obtained in the present study could contribute to the effective development of evaluation system of plant herbs based on molecular signatures related with their immunological functions in chicken IELs.

• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.2
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• pp.143-146
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• 2006

Historically, the common folk have made use of various wild herbs for both food and medicinal purposes. However, the misuse of these wild herbs can lead to adverse consequences, including severe poisoning in some cases. In cases of poisoning from wild herbs, patients can exhibit a variety of symptoms depending on the herbs involved, which in addition to gastrointestinal symptoms may include hemodynamic alteration and abnormal neurologic signs. In the present case, two patients were admitted to the emergency room with symptoms of toxicity after consuming Rhododendron brachycarpum liquor. Rhododendron brachycarpum and other wild herbs contain the toxic material grayanotoxin. Because of its serious toxic symptoms, great caution must be exercised in using rhododendrons for food and medicinal purposes.

• Herbal Formula Science
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• v.8 no.1
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• pp.11-37
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• 2000

This is a study on the methods of decocting prescriptions in SANGHANRON (傷寒論), and after this, numbers of results have been obtained. SANGHANRON was written by Chang-Ki (張機) in the 2nd century, so it reflexes the usage of prescriptions of previous age indirectly. And gave affects on the methods of decocting prescriptions to the oriental medicine doctors of next generation.Berore Han-DYnasty(漢代), there were not so many publications connected with Oriental Medicine. Besides, some books couldn't hand down to next generation due to the gap of time and space. As time goes by, letters in medical books changed little by little, so contents connected with decocting methods changed too. The effects of decoction and herb tea can be changed by the flexibility of methods of decocting medicines, so we have to decide what kinds of decocting methods should be taken and adapted to patients by the most effective way.In SANGHANRON, there are many kiny kinds of boiling methods, so DHAMG-Ki selected the most appropriate method considering deree and position of disease and condition of patient. But nowadays, due to inconvenient procedure of boiling and taking medicines, some methos are not in common in clinical medicin. So this study was started to look back upon the changes of decocting prescriptions and gave deffort to find out the propriety of variation of boiling prescriptions.The common method of decocting prescriptions in SANGHANRON is boiling down all the herbs at the same time. Except the commom method, there are some kinds of other methods - boiling down twice the prescription, boiling down some special herbs earlier of later than other herbs, complicated or special boiling methods of extract, etc. These kinds of decoting methods simplified as time pass by, but this expected therapeutic value. So we have to distinguish the methods -though complicated and troublesome- in clinical medicine to make perfection more perfect in treating patients, and further studies have to be followed to prove the propriety of these complicated methods.

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.2
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• pp.335-341
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• 2000

In order to search for blood anticoagulant substance from herbal extracts, we extracted with cold water (Fr. I), methanol (Fr. II) and hot water (Fr. III) from 93 commercially available herbs. The anticoagulant activity of herbal extracts was examined through the intrinsic pathway by activated partial thromboplastin time (APTT), the extriansic pathway by prothrombin time (PT) and the common pathway by thrombin time (TT). Onion, garlic, clove, fenugreek, mugwort, thyme and sage had on anticoagulant activity with intrinsic pathway and mint, italian seasoning, rosemary, turmeric, tarragon and wasabie had on anticoagulant activity with common pathway. Nobody had on anticogulant activity with extrinsic pathway. Among commerical herbs tested, clove cultivated in holland was selected because it showed the most potent anticoagulant activity among the samples investigated.

• Journal of Korean Medical classics
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• v.6
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• pp.41-53
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• 1993

The theory of 4 great doctors in Geum Won era has been considered as a most scientific medicine after SangHanRon of Jang, Jung Kyung. And it influence for all the later medical theory and practice. I have found a common points between their Fire and Fever pathology and constitutional pathology of Li, Je Ma. The results obtained are as follows. 1. On the Viewpoint of medical history, there is common points in the fact that the start of Geum Won 4 great doctor' principle had been drived from awakening of the abuse of warm and hot herbs based on Hwa Je Guk Bang in the last stage of Song dynasty, and that the appearance of Sa Sang medicine was from the scientific reflection against the currency of the animation by warm herbs which was popular in the Jo Sun dynasty. 2. The theory of Fire and Fever pathology of 4 great doctors has been fixed in the principle of Cold and Fever pathology of viscera and bowel in the Sa Sang medicine. 3. The pathological meaning of 'internal fire' in the conculusion by 4 great doctors has got scientific fruit by Sa Sang medicine in its theory of four constitutional psychology and the formation of four visceras. 4. It is considered that the study of DongUiSuSeBoWon is needed for the relation with former medical theories.

• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.1
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• pp.48-51
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• 2006

With well-being boom recently, the common people, but not experts, are increasingly taking in them directly by picking wild herbs. However, only experts can distinguish between edible vegetables and poisonous herbs from the wild herbs. Especially, it is not even easy for experts to distinguish them only by looking into buds in spring without flowers or fruit. So, sometimes many patients are being carried into the emergency room by the toxic symptom after taking by misunderstanding the poisonous herbs as edible vegetables. For herb intoxication as well as drug intoxication, what kinds of vegetables patients took in, and when and how much they took in them are important information for curing. Of course, in the case of intoxicating in the wild herbs, the patients can have a lot of symptoms and sings-hemodynamic alteration and abnormal neurologic sign as well as gastrointestinal symptoms-according to the kinds of herbs which they took in. Therefore, it is difficult to find the kinds of herbs which they took in through the specific symptoms. Recently we experienced a case with showing typical anticholinergic symptoms after ingestion of Scopolia japonica. As a result, the publicity activities about the wild plants needs because if the person without their previous knowledge take in the poisonous herbs, serious side effects can be produced..

• Journal of Ecology and Environment
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• v.31 no.3
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• pp.225-232
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• 2008

To find out the status and characteristics of exotic plants in the Gwangreung Forest, a representative forest ecosystem in central Korea, we surveyed the species composition, coverage, and habitat illuminance of exotic plant species in a set of quadrats established along roads and trails in and around the Gwangreung Forest and buffer zone areas, In 1932, only five species of exotic plants were found along paths and roads in the Gwangreung Forest. However, the number of species in the forest has dramatically increased since 2000, when Ambrosia artemisiifolia L. and A. trifida L. were first recorded, and in 2007, 38 species of exotic plants were recorded. Among the 11 families, 23 genera and 25 species of exotic plants recorded in the quadrats, Compositae was the most common family (11 species), and perennial herbs, 42%, were the most frequently occurring life type, followed by annual herbs (31%) and biennial herbs (19%). Plants of North American origin comprised 48% of exotic species identified in our surveys. Exotics were found most frequently in quadrats along roads in the forest, followed by the buffer zones and hiking trails. The number of species and individuals of exotic plants decreased as we moved deeper into the forest, but Aster pilosus Willd. and Erigeron annuus (L.) Pers. were identified along hiking trails in the interior, and appeared to be capable of spreading further and more rapidly into the forest than other species.