• 대한화학회지
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• 제67권5호
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• pp.353-361
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• 2023

이 연구에서는 2015 개정 교육과정에 따른 중학교 과학과 교과서의 물질 단원에 제시된 시각적 입자 표상의 활용 방식을 분석하였다. 4종의 과학 교과서의 물질 단원을 설명, 탐구, 평가 영역으로 구분하고 제시된 시각적 입자 표상의 활용 형태, 요구되는 활동 방식, 활동 수준을 분석하였다. 설명 영역의 경우 시각적 입자 표상은 주로 보조적 활용 형태로 제시되었으며 탐구와 평가 영역의 경우 직접적 활용 형태로 주로 제시되었다. 직접적 활용의 시각적 입자 표상의 활동 방식은 설명과 평가 영역에서는 주로 해석하기가, 탐구 영역에서는 다른 두 영역에 비해 완성하기와 생성하기가 비교적 높은 비율로 제시되었다. 활동 수준의 경우 설명 영역에서는 찾기 수준이, 탐구와 평가 영역에서는 유추하기 수준이 주로 나타났다. 이상의 결과를 바탕으로 과학 교과서 속 시각적 입자 표상의 제시와 활용 방향에 대한 시사점을 논의하였다.

• Journal of Astronomy and Space Sciences
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• 제31권2호
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• pp.159-167
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• 2014

Solar variability is widely known to affect the interplanetary space and in turn the Earth's electromagnetical environment on the basis of common periodicities in the solar and geomagnetic activity indices. The goal of this study is twofold. Firstly, we attempt to associate modes by comparing a temporal behavior of the power of geomagnetic activity parameters since it is barely sufficient searching for common peaks with a similar periodicity in order to causally correlate geomagnetic activity parameters. As a result of the wavelet transform analysis we are able to obtain information on the temporal behavior of the power in the velocity of the solar wind, the number density of protons in the solar wind, the AE index, the Dst index, the interplanetary magnetic field, B and its three components of the GSM coordinate system, $B_X$, $B_Y$, $B_Z$. Secondly, we also attempt to search for any signatures of influence on the space environment near the Earth by inner planets orbiting around the Sun. Our main findings are as follows: (1) Parameters we have investigated show periodicities of ~ 27 days, ~ 13.5 days, ~ 9 days. (2) The peaks in the power spectrum of $B_Z$ appear to be split due to an unknown agent. (3) For some modes powers are not present all the time and intervals showing high powers do not always coincide. (4) Noticeable peaks do not emerge at those frequencies corresponding to the synodic and/or sidereal periods of Mercury and Venus, which leads us to conclude that the Earth's space environment is not subject to the shadow of the inner planets as suggested earlier.

• The Korean Journal of Physiology and Pharmacology
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• 제7권3호
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• pp.157-162
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• 2003

Our earlier studies found a significant correlation between the activities of ranitidine N-oxidation catalyzed by hepatic flavin-containing monooxygenase (FMO) and the presence of mutations in exon 4 (E158K) and exon 7 (E308G) of the FMO3 gene in Korean volunteers. However, caffeine N-1 demethylation (which is also partially catalyzed by FMO) was not significantly correlated with these FMO3 mutations. In this study, we examined another common mutation (V257M) in exon 6 of FMO3 gene. The V257M variant, which is caused by a point mutation (G769A), was commonly observed (13.21% allele frequency) in our subjects (n=159). This point mutation causes a substitution of $Val^{257}$ to $Met^{257}$, with transformation of the secondary structure. The presence of this mutant allele correlated significantly with a reduction in caffeine N-1-demethylating activity, but was not correlated with the activity of N-oxidation of ranitidine. In a family study, the low FMO activity observed in a person heterozygous for a nonsense mutation in exon 4 (G148X) and heterozygous for missense mutation in exon 6 (V257M) of FMO3 was attributed to the mutations. Our results suggest that various point mutations in the coding regions of FMO3 may influence FMO3 activity according to the probe substrates of varying chemical structure that correlate with each mutation on the FMO3 gene.

• 한국간호교육학회지
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• 제7권2호
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• pp.245-253
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• 2001

The aim of this study is to describe degree of fatigue and factors related to fatigue in patients with rheumatoid arthritis. The subjects of the study consist of one hundred fifty-eight outpatients with rheumatoid arthritis at three university hospitals in Taegu between July 10 and August 30, 1999. The instrument used in this study was the Multidimensional Assessment of Fatigue developed by Belza et al.(1995) and revised by Jung, Bok Hee. Kim, Myung Ae(1998). Analysis of data was done by using the descriptive statistics, t-test, ANOVA and Duncan with SPSS program. The major findings can be summarized as follows: 1. Degree of fatigue in patient with Rheumatoid Arthritis was shown the average 22.91 out of the total scores 40. Four subscales of fatigue scores are common fatigue degree 6.37, fatigue timing at the last week 5.92, distress due to fatigue 5.40 and degree of daily activity fatigue 5.22. Among the realms of daily activity fatigue, outdoor activity(6.00), sexual life(5.84), doing the household(5.66), shopping(5.61), other exercise except stroll(5.54) were shown the high degree of fatigue and cooking(4.97), a stroll(4.48), recreation(4.35) showed the low degree of fatigue. 2. There were no significant differences on the total degree of fatigue according to demographic variables. But there were some significant differences on the subscale fatigue scores according to demographic variables. Degree of daily activity fatigue according to sex was shown significant difference (t=-2.358, p=.020), and according to education level was shown significant difference(F=3.938, p=.005) and common fatigue degree according to age was shown significant difference(F=2.853, p=.026). Conclusively fatigue is one of difficult problems for patients with rheumatoid arthritis. Therefore it is necessary to develop some nursing intervention for reducing fatigue of rheumatoid arthritis patients.

• Food Science and Biotechnology
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• 제18권3호
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• pp.776-781
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• 2009

A putative cyclomaltodextrinase (BHCD) gene was found from the genome of Bacillus halodurans C-125, which encodes 578 amino acids with a predicted molecular mass of 67,279 Da. It shares 42-59% of amino acid sequence identity with common cyclomaltodextrinase (CDase)-family enzymes. The corresponding gene was cloned by polymerase chain reaction (PCR) and the dimeric enzyme with C-terminal 6-histidines was successfully overproduced and purified from recombinant Escherichia coli. BHCD showed the highest activity against ${\beta}-CD$ at pH 7.0 and $50^{\circ}C$. Due to its versatile hydrolysis and transglycosylation activities, BHCD has been confirmed as a member of CDases. However, BHCD can be distinguished from other typical CDases on the basis of its novel multisubstrate specificity. While typical CDases have over 10 times higher activity on ${\beta}-CD$ than starch or pullulan, the CD-hydrolyzing activity of BHCD is only 2.3 times higher than pullulan. In particular, it showed significantly higher activity ratio of maltotriose to acarbose than other common CDase-family enzymes.

• 한국유기농업학회지
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• 제29권2호
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• pp.257-273
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• 2021

취나물 재배 시 문제가 되는 점무늬병(Septoria sp.)에 대해 항균활성을 나타내는 세균 P. polymyxa JE201를 분리하였다. JE201 균주를 이용하여 점무늬병 방제효과 포장검정을 시행한 결과, 대조구로 사용한 세레나데 맥스와 비슷한 정도의 방제효과를 나타낼 정도로 효과가 있었으며, 다른 식물 병원성 진균에 대한 항균활성 스펙트럼을 조사한 결과, 10종 중 9종에 대해서도 균사생장억제력이 크게 나타나는 것으로 보아, 앞으로 추가적인 연구를 통해 다른 병에도 적용할 수 있을 것으로 기대된다.

• 대한간호학회지
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• 제53권1호
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• pp.101-114
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• 2023

Purpose: This study aimed to identify regional differences in problem drinking among adult males in single-person households and predict the determinants. Methods: This study used data from the 2019 Community Health Survey. Geographically weighted regression analysis was performed on 8,625 adult males in single-person households who had been consuming alcohol for the past year. The Si-Gun-Gu was selected as the spatial unit. Results: The top 10 regions for problem drinking among adult males in single-person households were located in the Jeju-do and Jeollanam-do areas near the southern coast, whereas the bottom 10 regions were located in the Incheon and northern Gyeonggi-do areas. Smoking, economic activity, and educational level were common factors affecting problem drinking among this population. Among the determinants of regional disparities in problem drinking among adult males in single-person households, personal factors included age, smoking, depression level, economic activity, educational level, and leisure activity, while regional factors included population and karaoke venue ratio. Conclusion: Problem drinking among adult males in single-person households varies by region, and the variables affecting each particular area differ. Therefore, it is necessary to develop interventions tailored to individuals and regions that reflect the characteristics of each region by prioritizing smoking, economic activity, and educational level as the common factors.

• 과학교육연구지
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• 제43권1호
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• pp.157-172
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• 2019

이 연구의 목적은 난이도가 다른 생명과학공통성 발견 과제를 수행하는 동안 뇌 활성 차이를 분석하는 것이다. 이 연구에는 35명의 예비 생명과학교사들이 참여하였다. 이 연구는 뇌파 기록을 위한 블록디자인으로 설계되었다. 피험자들이 공통성 발견 과제를 수행하는 동안 뇌파가 수집되었다. sLORETA 분석 방법과 상대파워스펙트럼 분석 방법은 2개의 소재로 구성된 쉬운 난이도의 과제를 수행할 때와 5개의 소재로 구성된 어려운 난이도의 과제를 수행할 때 뇌 활성 차이를 분석하는 데에 이용되었다. 그리고 공통성 발견 과제의 난이도에 따라 활성화된 대뇌 피질과 피질하 영역의 역할을 조사하였다. 연구 결과 연구결과, 세타파의 경우, 쉬운 난이도 과제와 비교하여 어려운 난이도 과제 수행 시 세파타의 활성은 전두엽에서 유의미하게 감소하였고 후두엽에서는 증가하였다. 알파파의 경우, 쉬운 난이도 수행시보다 어려운 난이도의 과제를 수행할 때 전두엽에서 알파파의 활성이 유의미하게 감소하였다. 베타파의 활성은 어려운 난이도의 과제를 수행할 때 쉬운 난이도의 과제 수행시보다 전두엽, 두정엽, 후두엽에서 유의미하게 감소하였다. 마지막으로 감마파의 경우 쉬운 난이도의 과제를 수행할 때와 비교하여 어려운 난이도의 과제를 수행할 때 감마파의 활성이 전두엽에서는 감소하였고 두정엽과 측두엽에서는 활성이 증가하였다. 공통성 발견 과제의 난이도 수준은 대상이랑(cingulate gyrus), 쐐기소엽(cuneus), 혀이랑(Lingual gyrus), 후측 대상피질(posterior cingulate), 쐐기전소엽(precuneus), 엽하영역(sub-gyral)에 영향을 준다는 것을 보여주었다. 따라서 공통성 발견 과제의 난이도는 이미지로부터 인출된 시각적 정보와 위치정보를 통합하는 과정, 대상의 속성을 비교하고 필요한 정보를 선택하는 과정, 선택한 정보의 시각적 작업 기억 과정, 이 모든 과정에서의 주의집중에 대한 인지과정에 영향을 준다고 할 수 있다.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2004년도 추계학술대회 논문집
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• pp.111-116
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• 2004

This study is aimed to be used as basic data to plan Korean style cohousing for double-income families in the future by studying their lifestyle, housing needs and housing awareness on cohousing. The results of the study are as follows. 1) As for the life style of the subject families, it was a housewife that mainly does the household affairs despite of the status of double-income family. Also, as for the social activity, almost half of the respondents said that the spending in child-care facilities was not sufficient and wanted to send their children to ones within their neighborhood. 2) As far as housing awareness on cohousing concerned, among specific items, the child care area, the household affairs division area, and participatory awareness of residents in housing planning and management got higher scores, while as for awareness on utilizing common space, using the common hobby rooms, promenades and benches, exercise facilities, common yard, and study rooms got higher scores. When asked about the necessity for cohousing in Korea, they gave very positive answers, but the answer to their willingness to reside in it was less positive. 3) Summarizing the housing needs on cohousing, it turned out that more people wanted to reside in suburban area with others having common grounds with them as for a desirable residence environment. They wanted the neighborhood to be composed of 10${\sim}$29 families, and medium-density semi-detached house occupied by owners. They wanted a mixture of independent management and entrust management for managing common facilities, and common meal once a week. They wanted indoor exercise facilities to be more extended than other common facilities, and the house of $100m^{2}{\sim}130m^{2}$ with 3 bedrooms, 2 bath rooms, and a large living room and dining room.

• 성인간호학회지
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• 제26권4호
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• pp.383-392
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• 2014

Purpose: The purpose of this study was to describe the degrees of body image, self esteem and Health Related Quality Of Life (HRQOL), and to identify factors related to these variables in patients with Crohn's disease. Methods: A descriptive cross sectional survey design was used. The 148 participants were the patients with Crohn's disease, recruited conveniently from one metropolitan hospital located in Seoul, Korea. The collected data were analyzed with SPSS/WIN program. Results: Patients with severe illness activity reported significantly lower body images than those of the others. Education levels and working states affected self-esteem positively, while the number of operations and illness activity affected self-esteem negatively. Hospitalization and illness activity affected HRQOL negatively. Body image, self esteem, and HRQOL were positively correlated to each other with statistical significance. Illness activity was a common factor to affect body image, self esteem, and HRQOL. Body image was an influential factor on HRQOL as well as illness activity in patients with Crohn's disease. Conclusion: As a result, this study suggested a necessity for developing an intervention study to lower the illness activity and heighten the body image among the patients with Crohn's disease.