• Herbal Formula Science
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• v.25 no.3
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• pp.391-412
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• 2017

Objective : In this study, we searched the experimental research about combined treatment of anticancer drug and herbal medicine for killing or inhibiting proliferation of Cancer cells searched in OASIS and KISS. This study aimed to analyze the experimental research paper about anticancer drug combined treatment with herbal medicine. Methods : We collected the research paper including killing or inhibiting proliferation of Cancer cells in OASIS and KISS using keyword anticancer drug with herbal medicine, tumor suppressor with herbal medicine, inhibition of Cancer with herbal medicine and combined treatment with herbal medicine. Assorting by cancer cells, we analyzed experimental results cancer cell viability, anticancer drug dosage, tumor weight and survival rate. Also, we checked the effects of herbal medicine on cancer and additive effect reducing side effect of anticancer drug. Results : Total 45 studies were selected. 38 studies reported combined treatment of anticancer drug and herbal medicine was more effective than only anticancer drug. The death of cancer cells was synergistically induced by the cotreatment of anticancer drug and herb extracts. The studies suggest that the cotreatment of anticancer drug and herb extracts could reduce side effect of anticancer drug. In addition, some studies reported cotreatment mechanism like apoptotic death signal processes. In combined treatment of anticancer drug and herb extracts, The expression of Fas/Fas L, Bax, Bcl2, Caspase-3 etc.. was markedly increased in cancer cells. Conclusions : Our results suggest that anticancer drug combined treatment with herbal medicine could be efficient for killing or inhibiting proliferation of cancer cells. However, this paper had some limitation as follows: First, collected studies have been published only for korean journal. Second, results of research and effects of combined treatment are not collected objectively. To solve these problems, more objective and balanced studies should be performed.

• Journal of Korean Medicine for Obesity Research
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• v.1 no.1
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• pp.77-83
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• 2001

We wanted to study the effect of Taeyeumjowee-tang and electroacupunctre combined-therapy on obese patients. From 1 March, 2000 to 30, September, 2000 we studied 33 out-ward patients who clinically diagnosed obesity and classified Tae-Em-In by QSCC(Questionnaire of Sasang Constitution Classification). We treated the patients by electroacupuncture therapy and taeyeumjowee-tang for 6 weeks, We investigated the change of mean body weight, mean body mass index, mean obesity degree, percent body fat and waist-hip circumference ratio. To analyze the results we used repeat measure method by SPSS ver 7.5. The results were as follows: 1. From $70.4{\pm}11.4\;to\;64.9{\pm}8.7$, mean body weight was significantly decreased according to combined-therapy. 2. From $27.2{\pm}3.2\;to\;24.6{\pm}2.7$, mean BMI was significantly decreased according to combined-therapy. 3. From $116.7{\pm}13.9\;to\;104.4{\pm}12.1$, mean obesity degree was significantly decreased according to combined-therapy. 4. From $32.1{\pm}6.8\;to\;27.4{\pm}7.5$, percent body fat was significantly decreased according to combined-therapy. 5. From $0.90{\pm}0.06\;to\;$0.86{\pm}0.06$, waist-hip circumference ratio was significantly decreased according to combined-therapy. In this study we knew the combined-therapy of electroacupuncture and taeyeumjowee-tang is very efficient in obese patient.

• YAKHAK HOEJI
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• v.29 no.1
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• pp.11-17
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• 1985

The behavioral effects of propranolol (60mg/kg) and metoprolol (100mg/kg) each alone and coadministered orally with cinnarizine (100mg/kg) were investigated and compared with each of betablockers alone treated group in rodents. Propranolol showed depressive effects through locomotor activity, conditioned avoidance response, rota-rod test, traction test, and analgesic effect in mice. When combined with cinnarizine and propranolol, the behavioral depressive effect of propranolol was reduced comparing with propranolol alone treated group. However, metoprolol alone or combined with cinnarizine didn't showed any behavioral depressive effect so much as propranolol.

• ETRI Journal
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• v.16 no.3
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• pp.11-26
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• 1994

In Korea, the price schedule for local telephone combines two-part tariffs and peak-load pricing subject to rate-of-return (RoR) regulation. Although the effect of RoR regulation on two-part tariffs or peak-load pricing has been separately analyzed by many authors in some detail, the behaviour of regulated firm under combined two-part and peak-load pricing has not been studied until now. This paper examines the effect of regulation on the rate structure and welfare under combined two-part and peak-load pricing.

• Natural Product Sciences
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• v.11 no.4
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• pp.189-192
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• 2005

Anti-amnestic activities of Korean red ginseng (Ginseng Radix Rubra) and Crude drug-combined preparations (RGCDP-1, RGCDP-2, and RGCDP-3) were evaluated by the animal experiment. RGCDP-1 and RGCDP-2 were prepared based on Korean folk prescriptions, 'Chongmyongtang' and 'Guibitang', respectively, while RGCDP-3, by a combination of both. Among the three preparations, RGCDP-3 was found to show the most potent anti-amnestic activity as evaluated by the passive avoidance test with mice, indicating synergistic action by combined effect of RGCDP-1 and RGCDP-2.

• Journal of the Korean Institute of Landscape Architecture
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• v.27 no.2
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• pp.9-18
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• 1999

In this study the relative effects among trees, cars, wires and building facades on visual preference are measured with the photo-montage scenes, which were synthesized by computer graphic programs. In addition to these experiments, the interaction of each elements of streetscapes have been investigated. The results of this study can be summarized as follows ; (1) It was found that trees had a remarkable positive effect on preference for streetscapes, wires had a moderate negative effect, cars had a trivial effect and the effects of building facades were medium. (2) It was investigated that the building of residential type was most preferred among commercial, residential, and office building types. The next preferred building facade was the commercial type. (3) The interaction of each element of streetscapes also have effects on preference. Especially, it was found that the combined effects of building-wire and building-cars were more notable than other combined effects of two elements.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.1
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• pp.119-123
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• 2014

The purpose of this study is to report the effect of combined acupuncture treatment on acute ankle sprain patients. The subjects included in this study were 15 acute ankle sprain patients who visited Jaseng Hospital of Korean Medicine from Oct. 15th, 2012 to Feb. 8th, 2013. We treated 15 patients with combined acupuncture treatment. The treatment consisted of Hwangrunhaedok-tang (Huanglianjiedutang) pharmacupuncture, electroacupuncture (applied to GB39, ST36 on the affected side), acupuncture (applied to TE17, SI6 on the unaffected side with Dong-Qi therapy). To assess the effect of treatment, the numeric rating scale (NRS) was applied before and after treatment. After first combined acupuncture treatment, the NRS scores significantly decreased from $8.33{\pm}0.94$ to $2.26{\pm}0.44$ (p<0.01). We suggested that Combined acupuncture treatment are effective and useful on acute ankle sprain. And, further studies will be needed.

• Steel and Composite Structures
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• v.51 no.2
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• pp.117-126
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• 2024

There are many challenges in the construction of large-section tunnels, such as extremely soft rock and fractured zones. In order to solve these problems, the confined concrete support technology is proposed to control the surrounding rocks. The large-scale laboratory test is carried out to clarify mechanical behaviours of the combined confined concrete and traditional I-steel arches. The test results show that the bearing capacity of combined confined concrete arch is 3217.5 kN, which is 3.12 times that of the combined I-steel arch. The optimum design method is proposed to select reasonable design parameters for confined concrete arch. The parametric finite element (FE) analysis is carried out to study the effect of the design factors via optimum design method. The steel pipe wall thickness and the longitudinal connection ring spacing have a significant effect on the bearing capacity of the combined confined concrete arch. Based on the above research, the confined concrete support technology is applied on site. The field monitoring results shows that the arch has an excellent control effect on the surrounding rock deformation. The results of this research provide a reference for the support design of surrounding rocks in large-section tunnels.

• The Journal of Pediatrics of Korean Medicine
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• v.34 no.3
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• pp.81-96
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• 2020

Objectives This study aims to evaluate the effect of acupuncture combined with rehabilitation treatment for cerebral palsy in children. Methods 7 electro-database (PubMed, CENTRAL, CNKI, DBpia, KISS, OASIS, KJTK) were searched for using the keywords "cerebral palsy AND acupuncture" which study is designed in randomized controlled trials (RCTs). Results 10 out of 303 studies were included in analysis after screened. Acupuncture combined with rehabilitation treatment had a significant effect on motor function. Only 1 study reported minor adverse effects. Conclusions All of the studies have shown acupuncture combined with conventional rehabilitation treatment was effective in cerebral palsy. Additional well-designed studies are needed to justify the effectiveness of acupuncture in cerebral palsy.

• Korean Journal of Applied Biomechanics
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• v.28 no.2
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• pp.119-125
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• 2018

Objective: The purpose of this study was to compare the effect of different 12-week exercise programs for posture correction on postural alignment in elderly women. Method: The study included 36 elderly women who were randomly divided into 3 groups: Group A (core exercise, n=12), Group B (combined exercise, n=12), and Group C (Pilates exercise, n=12). Postural alignment was measured using 6 variables in frontal and sagittal planes. Two-way mixed analysis of variance was used to compare the effect of exercise program types on postural alignment and a paired t-test was used to compare differences in postural alignment after exercise. Results: The core exercise group showed statistically significant improvement (p<.05) in multiple upper and lower body postural alignment measurements. The combined exercise and Pilates exercise groups showed statistically significant improvement (p<.05) in upper body measurements alone. Conclusion: Core exercise, combined exercise, and Pilates exercise improved postural alignment in elderly woman through improvement in muscle strength and ligament flexibility around the spine and pelvis.