• Communications for Statistical Applications and Methods
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• 제8권3호
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• pp.685-696
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• 2001

Robust design is an approach to reducing performance variation of response values in products and processes. In the Taguchl parameter design, the product-array approach using orthogonal arrays is mainly used. However, it often requires an excessive number of experiments. An alternative approach, which is called the combined-array approach, was suggested by Welch et. al. (1990) and studied by others. In these studies, only single response variable was considered. We propose how to simultaneously optimize multiple responses when there are correlations among responses, and when we use the combined-array approach to assign control and noise factors. An example is illustrated to show the difference between the Taguchi's product-array approach and the combined-array approach.

• 통합자연과학논문집
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• 제6권1호
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• pp.39-45
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• 2013

Robust design is an approach to reducing performance variation of quality characteristic values in quality engineering. Taguchi has an idea that mean and variation are handled simultaneously to reduce the expected loss in products and processes. In the Taguchi parameter design, the product-array approach using orthogonal arrays is mainly used. However, it often requires an excessive number of experiments. An alternative approach, which is called the combined-array approach, was studied. In these studies, only single quality characteristic (or response) was considered. In this paper we propose how to simultaneously optimize for multiple quality characteristics (or multiresponse) using desirability function when we used the combined-array approach to assign control and noise factors.

• Advances in concrete construction
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• 제7권4호
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• pp.263-275
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• 2019

In the present work, Granulated Blast Furnace Slag (GBFS) and Fly ash (FA) were used as partial replacement of Natural Sand (NS) and Ordinary Portland Cement (OPC) by weight. One control mix, one with GBFS, three with FA and three with GBFS-FA combined mixes were prepared. Replacements were 50% GBFS with NS and 20%, 30% and 40% FA with OPC. Preliminary investigation on development of compressive strength was carried out at 7, 28 and 90 days to ensure sustainability of waste materials in concrete matrix at room temperature. After 90days, thermo-mechanical study was performed on the specimen for a temperature regime of $200^{\circ}-1000^{\circ}C$ followed by furnace cooling. Weight loss, visual inspection along with colour change, residual compressive strength and microstructure analysis were performed to investigate the effect of replacement of GBFS and FA. Although adding waste mineral by-products enhanced the weight loss, their pozzolanicity and formation history at high temperature played a significant role in retaining higher residual compressive strength even up to $800^{\circ}C$. On detail microstructural study, it has been found that addition of FA and GBFS in concrete mix improved the density of concrete by development of extra calcium silicate gel before fire and restricts the development of micro-cracks at high temperature as well. In general, the authors are in favour of combined replacement mix in view of high volume mineral by-products utilization as fire protection.

• 품질경영학회지
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• 제24권2호
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• pp.142-157
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• 1996

Robust design in industry is an approach to reducing performance variation of quality characteristic values in products and processes. In the Taguchi type robust design, the product array approach using orthogonal arrays is mainly used. However, it often requires an excessive number of experiments. In this paper, for the combined array approach to assign control and noise factors, we propose how to simultaneously optimize multiple quality characteristics. Two examples are illustrated to show the difference between the product-array approach and the combined-array approach.

• 통합자연과학논문집
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• 제14권3호
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• pp.73-77
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• 2021

Robust design is an approach to reduce the performance variation of mutiple responses in products and processes. In fact, in many experimental designs require the simultaneous optimization of multiple responses. In this paper, we propose how to simultaneously optimize multiple responses for robust design when data are collected from a combined array. The proposed method is based on the quadratic loss function. An example is illustrated to show the proposed method.

• Journal of Microbiology and Biotechnology
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• 제11권4호
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• pp.663-667
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• 2001

A new secondary metabolite was isolated from the culture broth and mycelium of Streptomyces sp. collected from marine sediment. The structure of this compound was determined to be N-formylantimycic acid methyl ester, an acyclic derivative of antimycin, on the basis of combined chemical and spectral methods. The structure-activity relationship of antimycins is discussed.

• Journal of Microbiology and Biotechnology
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• 제10권2호
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• pp.176-180
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• 2000

Three polyene macrolide antibiotics including two new compounds were isolated from the culture mycelia of a Streptomyces species. The structures of these metabollites were determined as elizabethin, a previously reported 28-membered macrolide and two analohs, using combined spectroscopic methods. These compounds exhibited antifungal activity and cytotoxicity against a juman leukemia cell.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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• pp.90-94
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• 2001

Wondonins A and B, aromatic alkaloids of an unprecedented skeletal class have been isolated form and association of the sponges Poecillastra wondoensis and Jaspis sp. In addition, four novel bromotyrosine-derived metabolites, psammaplins $A_1$ and $A_2$, aplysinellins A and B, have been isolated from the tropical sponge Aplysinella rhax. The structures of these compounds have been determined on the basis of combined chemical and spectral analyses. The new compounds exhibited significant cytotoxicity and antiangiogenic activity as well as inhibitory activities against farnesyl protein transferase and leucine aminopeptidase. In addition to these compounds, several bioactive metabolites have been isolated from sponges of Korean and tropical waters.

• Natural Product Sciences
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• 제21권4호
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• pp.237-239
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• 2015

Sarcotragin C (1), a new sesterterpene metabolite was isolated from a Sarcotragus sp. sponge collected from Chuja Island, Korea. On the basis of the combined spectroscopic analyses, the structure of this compound was determined to be a linear norsesterterpene containing a leucine-derived ${\gamma}-lactam$ moiety. This compound exhibited moderate cytotoxicity against K562 and A549 cell-lines.

• Asian-Australasian Journal of Animal Sciences
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• 제27권9호
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• pp.1336-1344
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• 2014

The effects of various packaging systems, vacuum packaging (VACP), medium oxygen-modified atmosphere packaging (50% $O_2/20%$ $CO_2/30%$ $N_2$, MOMAP), MOMAP combined with vacuum skin packaging (VSP-MOMAP), high oxygen-MAP (80% $O_2/20%$ $CO_2/30%$ $N_2$, HOMAP), and HOMAP combined with VSP (VSP-HOMAP), on the activity of antioxidant enzyme, and oxidation and color stabilities in sliced Hanwoo (Korean cattle) beef loin were investigated at $4^{\circ}C$ for 14 d. Higher (p<0.05) superoxide dismutase activity and total reducing ability were maintained in VSP-MOMAP beef than in HOMAP beef. Lipid oxidation (2-thiobarbituric acid reactive substances, TBARS) was significantly (p<0.05) retarded in MOMAP, VSP-MOMAP, and VSP-HOMAP beef compared with HOMAP beef. Production of nonheme iron content was lower (p<0.05) in VSP-MOMAP beef than in HOMAP beef. Red color ($a^*$) was kept higher (p<0.05) in VSP-MOMAP beef compared with MOMAP, HOMAP, and VSP-HOMAP beef. However, VACP beef was found to have the most positive effects on the antioxidant activity, oxidation and red color stabilities among the various packaged beef. These findings suggested that VSP-MOMAP was second to VACP in improving oxidation and color stabilities in sliced beef loin during chill storage.