• 대한의용생체공학회:의공학회지
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• 제31권3호
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• pp.177-186
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• 2010

In 3D ultrasound color Doppler imaging (CDI), 8-16 pulse transmissions (ensembles) per each scanline are used for effective clutter rejection and flow estimation, but it yields a low volume acquisition rate. In this paper, we have evaluated three flow estimation methods: autoregression (AR), eigendecomposition (ED), and autocorrelation combined with adaptive clutter rejection (AC-ACR) for a small ensemble size (E=4). The performance of AR, ED and AC-ACR methods was compared using 2D and 3D in vivo data acquired under different clutter conditions (common carotid artery, kidney and liver). To evaluate the effectiveness of three methods, receiver operating characteristic (ROC) curves were generated. For 2D kidney in vivo data, the AC-ACR method outperforms the AR and ED methods in terms of the area under the ROC curve (AUC) (0.852 vs. 0.793 and 0.813, respectively). Similarly, the AC-ACR method shows higher AUC values for 2D liver in vivo data compared to the AR and ED methods (0.855 vs. 0.807 and 0.823, respectively). For the common carotid artery data, the AR provides higher AUC values, but it suffers from biased estimates. For 3D in vivo data acquired from a kidney transplant patient, the AC-ACR with E=4 provides an AUC value of 0.799. These in vivo experiment results indicate that the AC-ACR method can provide more robust flow estimates compared to the AR and ED methods with a small ensemble size.

• 한국임상수의학회지
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• 제20권2호
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• pp.145-149
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• 2003

개의 정상안혈관저항지수와 그 재현성을 측정하고자 컬러도플러 초음파를 이용하여 본 실험을 수행하였다. 내측 긴 후모양체 동맥, 모양체 동맥, 안동맥의 혈관저항지수의 정상범주를 측정하기 위하여 58두의 개에서 컬러도플러 초음파를 실시하였다. 정상견에서 내측 긴 후모양체동맥, 모양체동맥, 안동맥의 저항지수(%)를 측정한 결과, 그 수치는 각각 0.67$\pm$0.07, 0.70$\pm$0.06, 그리고 0.08$\pm$0.04이었으며, 모든 혈관의 저항지수는 좌우안구간에 차이가 없었으며, 성별이나 두개골 형태가 미치는 영향도 없는 것으로 판명되었다. 안혈관 저항지수의 반복측정에 따른 오차를 평가하기 위해서 4회 반복 측정한 결과, 안동맥저항지수의 반복측정변이계수가 4.1%로 가장 낮았으며 긴 후모양체동맥과 모양체동맥의 저항지수의 반복측정변이계수는 각각 12.9%와 7.8%로 모든 동맥에서 높은 재현성을 보였다. 이상의 결과로 보아, 컬러도플러 초음파가 개의 안구 및 안와의 혈순환에 대한 객관적인 측정자료를 제시하는데 매우 유용한 지표인 것으로 판단된다.

• 대한수의학회지
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• 제45권3호
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• pp.423-427
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• 2005

Color Doppler imaging (CDI) was carried out to evaluate the anesthetics effect on ophthalmic circulation using CDI-derived resistive index (RI) values. CDI was preformed on 24 dogs, and RI values were calculated for the medial long posterior ciliary artery (mLPCA) and ophthalmic artery (OA) before and after administration of anesthetics. After administration of benoxinate or acepromazine, a significant change of the mLPCA RI was not found. But, a significant decrease of the RI following ketamine (p < 0.001) or xylazine (p < 0.01) administration could be observed as compared with the self-control. Mean RI value of OA also showed this same trend. Intraocular pressure was significantly decrease following benoxinate (p < 0.01), acepromazine (p < 0.01), and xylazine (p < 0.001) administration within normal range. The results suggest that some anesthetics influence on ophthalmic vascular resistance. Therefore, chemical restraint was carefully used in clinical application of CDI-derived RI measurement. Particularly, benoxinate and acepromazine is useful chemical restraint without a change of the ophthalmic vascular resistance.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제20권3호
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• pp.175-202
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• 2016

Ultrasound imaging is a widely used tool for visualizing human body's internal organs and quantifying clinical parameters. Due to its advantages such as safety, non-invasiveness, portability, low cost and real-time 2D/3D imaging, diagnostic ultrasound industry has steadily grown. Since the technology advancements such as digital beam-forming, Doppler ultrasound, real-time 3D imaging and automated diagnosis techniques, there are still a lot of demands for image quality improvement, faster and accurate imaging, 3D color Doppler imaging and advanced functional imaging modes. In order to satisfy those demands, mathematics should be used properly and effectively in ultrasound imaging. Mathematics has been used commonly as mathematical modelling, numerical solutions and visualization, combined with science and engineering. In this article, we describe a brief history of ultrasound imaging, its basic principle, its applications in obstetrics/gynecology, cardiology and radiology, domestic-industrial products, contributions of mathematics and challenging issues in ultrasound imaging.

• 한국산학기술학회논문지
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• 제8권5호
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• pp.1047-1056
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• 2007

기본적으로 초음파 영상 시스템은 반사 계수를 보는 B-모드와 혈류의 속도를 구하는 도플러 영상 모드를 구비하고 있다. 본 논문에서는 도플러 영상 모드에서 혈류의 속도를 나타내는 도플러 주파수가 펄스반복주파수의 1/2을 초과하는 경우 발생하는 에일리어싱 현상을 검출해 보상하는 새로운 방법을 제시하고 컴퓨터 시뮬레이션을 통하여 타당성을 보여준다. 본 논문에서 제안하는 방법은 추정 가능한 도플러 주파수를 확장시켜 줄 뿐만 아니라 잡음에 대해서도 강인한 특성을 가진다. 시뮬레이션 결과 신호 대 잡음비가 약 20dB로 낮은 경우에도 에일리어싱을 제대로 보상할 수 있음을 알 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제16권3호
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• pp.279-288
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• 1995

Ultrasonic Doppler systems for the purpose of estimating blood flow velocity, blood flow volume, and flow imaging are commonly used due to advantages of non-invasive and real time observation. Specially, the technical developments of color flow mapping (2-D Doppler) systems have made a relatively rapid progress. However, the 2-D Doppler systems have several problems, such as the range ambiguity, low signal to noise ratio, and slow frame rate. The slow frame rate problem is resolved by using the spatial average which is a method to acquire more data samples for mean frequency estimation. In this paper, spatial average method using the 2nd order sampling instead of quadrature sampling is proposed. The experimental results show that the proposed methods have good performance and easy application to the color flow mapping system.

• 대한정형외과 초음파학회지
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• 제6권1호
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• pp.10-14
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• 2013

모기질세포종은 모발의 기질세포로부터 발생하는 양성 피부종양이다. 이것은 주로 두 경부 및 상지에 호발한다. 수술 전 진단의 정확성은 낮으며 단순방사선 검사만 시행한 후 절제생검을 하기도 한다. 저자들은 컬러도플러 초음파를 이용해서 쉽게 진단할 수 있었던 견부에 발생한 모기질세포종에 대해 보고하고자 한다. 초음파를 이용한 진단은 비용효과적인 측면 뿐만 아니라 종양의 내부에 대해 자세한 정보를 알 수 있다는 점에서 전산화 단층촬영이나 자기공명영상보다 더 손쉽고 유용한 진단방법으로 생각된다.

• 대한기관식도과학회지
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• 제3권1호
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• pp.159-163
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• 1997

The complications of deep neck infection have become much less common in the antibiotic era. The vascular complications of deep neck infection can have devasting consequences. Most commonly, the internal carotid artery is involved, although the common carotid and external carotid artery can also be affected.0 the cases of patients with a protracted course, recurrent bleeding, cranial neuropathies, or trismus, the presence of vascular complications must be considered. Appropriate imaging should be carried out to allow the localization of the infection and ascertain the status of the vessels in the neck The vascular structures can be imaged with duplex doppler or color doppler flow ultrasound to see the flow between the mass and vessels. Also angiography plays a key role in the diagnosis and management of vascular complication of deep neck infection. Prompt diagnosis and treatment of these patients is necessary to prevent significant hemmorrhagic complications. We experienced a case of pseudoaneurysm of the common carotid artery secondary to deep neck infection treated successfully with surgical excision in 45-year-old-male.

• 한국산학기술학회논문지
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• 제12권5호
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• pp.2261-2266
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• 2011

초음파 컬러 유동 사상에서 가장 많이 사용되는 Kasai 알고리듬은 래그-1 자기상관 방법으로서 적은 계산량으로 비교적 우수하게 도플러 평균주파수를 추정한다. 하지만 특히 깊은 곳을 영상화하는 경우 낮은 신호 대 잡음비로 인해 추정성능이 저하된다. 본 논문에서는 낮은 신호 대 잡음비에서도 Kasai 알고리듬보다 우수한 디에일리어스된 래그-2 자기상관방법을 제안하고 시뮬레이션을 통해 성능을 검증하였다. 제안한 방법은 잡음이 존재하는 경우 도플러 평균주파수 추정 성능을 평균 자승 오차 측면에서 전반적으로 약 2~3dB 정도 개선시켜줌을 확인하였다.

• Journal of Chest Surgery
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• 제24권3호
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• pp.265-270
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• 1991

Since advent of the prosthetic cardiac valve replacement, much efforts for accurate assessing value function in-vivo have been attempted. To evaluate the postoperative functional and morphological status of the replaced cardiac valve prosthesis, 33 patients with valve replacement were studied by transthoracic and transesophageal 2-dimensional echocardiac imaging as well as by color Doppler flow velocity imaging. Twenty four patients had mitral valve replacement. 6 patients had aortic valve replacement and 3 patients had both mitral and aortic valve replacement. There were 34 mechanical and 2 biological prosthesis. Comparing to transthoracic echocardiography, transesophageal approach showed transvalvular regurgitant jet flow amid the prosthetic mitral valve ring during. systole and much clear visualization of cardiac chamber behind prosthesis which could give shadowing effect to ultrasound beam. According to the quantitative grading by the length and area of mitral regurgitant flow, 24 out of 27 mitral valves revealed mild degree regurgitation considered as physiological after prosthetic bileaflet valve replacement and the other 3 valves including 2 biological prosthesis had moderate degree regurgitation which was regarded as pathologic one. 2 cases of left atrial thromboses and 1 case of paravalvular leakage which were not visible by transthoracic approach were identified by transesophageal echocardiography in patients with mitral valve replacement and patients with aortic valve replacement respectively. We conclude that in patients with prosthetic mitral valve replacement, transesophageal 2-dimensional imaging with color Doppler can suggest reliable information beyond that available from the transthoracic access even though it gives patient some discomfort to proceed.