• Journal of East-West Nursing Research
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• v.10 no.1
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• pp.53-60
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• 2004

The purpose of this study was to examine the effects of the short term education and reinforcement program to health promotion in women in mid-life. This study has been done between February and April, 2004 and the subjects of the study were 26 women in mid-life. The treatment intervention was applied during total 8 weeks as 5 days for the short term education and 7 weeks for reinforcement with 1 time per a week. The short term education included health education for menopause, effect of exercise, healthy diet, management of stress and management of chronic illness and stretching exercise and recreation. The collected data were processed using the SPSS Win(12.0) program and analyzed using Wilcoxon Signed Ranks Test. The result of this study are as follows : 1. The short term education and reinforcement program significantly effected on the total cholesterol, HDL-cholesterol, triglyceride. 2. The short term education and reinforcement program significantly effected on the anxiety, but not depression. 3. The short term education and reinforcement program non significantly effected on the sleep disturbance and self-efficacy of exercise. 4. The short term education and reinforcement program significantly effected on the practice of healthy life. In conclusion, the short term education and reinforcement program effected on the physical health index, anxiety and practice of healthy life.

• Journal of Ginseng Research
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• v.46 no.6
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• pp.738-749
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• 2022

Background: Ginseng possesses antitumor effects, and ginsenosides are considered to be one of its main active chemical components. Ginsenosides can further be hydrolyzed to generate secondary saponins, and 20(R)-panaxotriol is an important sapogenin of ginsenosides. We aimed to synthesize a new ginsengenin derivative from 20(R)-panaxotriol and investigate its antitumor activity in vivo and in vitro. Methods: Here, 20(R)-panaxotriol was selected as a precursor and was modified into its derivatives. The new products were characterized by ¹H-NMR, ¹³C-NMR and HR-MS and evaluated by molecular docking, MTT, luciferase reporter assay, western blotting, immunofluorescent staining, colony formation assay, EdU labeling and immunofluorescence, apoptosis assay, cells migration assay, transwell assay and in vivo antitumor activity assay. Results: The derivative with the best antitumor activity was identified as 6,12-dihydroxy-4,4,8,10,14-pentamethyl-17-(2,6,6-trimethyltetrahydro-2H-pyran-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl(tert-butoxycarbonyl)glycinate (A11). The focus of this research was on the antitumor activity of the derivatives. The efficacy of the derivative A11 (IC₅₀ < 0.3 µM) was more than 100 times higher than that of 20(R)- panaxotriol (IC₅₀ > 30 µM). In addition, A11 inhibited the protein expression and nuclear accumulation of the hypoxia-inducible factor HIF-1α in HeLa cells under hypoxic conditions in a dose-dependent manner. Moreover, A11 dose-dependently inhibited the proliferation, migration, and invasion of HeLa cells, while promoting their apoptosis. Notably, the inhibition by A11 was more significant than that by 20(R)-panaxotriol (p < 0.01) in vivo. Conclusion: To our knowledge, this is the first study to report the production of derivative A11 from 20(R)-panaxotriol and its superior antitumor activity compared to its precursor. Moreover, derivative A11 can be used to further study and develop novel antitumor drugs.

• East Asian mathematical journal
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• v.14 no.1
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• pp.35-41
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• 1998

In the present paper we introduce a new class of analytic functions and give some results.

• Bulletin of the Korean Chemical Society
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• v.13 no.1
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• pp.100-101
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• 1992

• East Asian mathematical journal
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• v.12 no.1
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• pp.85-92
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• 1996

• Journal of the Korean Chemical Society
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• v.37 no.2
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• pp.265-268
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• 1993

• Proceedings of the Zoological Society Korea Conference
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• 1997.10b
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• pp.325-325
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• 1997

No Abstract, See Full Text

• Journal of Korean Society of Rural Planning
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• v.27 no.3
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• pp.1-9
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• 2021

It is important for residents to give opinions and participate in urban regeneration projects. Urban regeneration college is being operated to strengthen the capacity of residents. In this study, the educational satisfaction of the students was surveyed while conducting the program of urban regeneration college. By analyzing survey, we intend to derive implications when constructing an urban regeneration college education program. The survey was conducted on 215 students from urban regeneration college in y-gun. Analysis was performed using the spss24.0 program. As a result of factor analysis, it was classified into three factors: education design, education culture, and education support. All three factors had significant differences in educational satisfaction. Satisfaction with education had a significant effect on the possibility of village development. Satisfaction was different according to the contents of the educational program according to the awareness of urban regeneration. For those who are aware of urban regeneration, educational culture among educational programs has more influence on educational satisfaction. Those who were not aware of urban regeneration had an effect on education support and education satisfaction. The results of this study can be used as basic data when planning educational programs for urban regeneration college.

• Korean Medical Education Review
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• v.22 no.1
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• pp.16-27
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• 2020

The accreditation process (AccP) is both an opportunity and a burden for medical schools-which one it becomes depends on how medical schools recognize and utilize the AccP. In other words, if a medical school recognizes the AccP only as a formal procedure or as a means for continuing medical education, it will be a burden for the medical school. However, if a medical school recognizes the real and positive value of the AccP, it can be both an opportunity and a tool for developing medical education. The educational value of the AccP is to improve the quality, equity, and efficiency of medical education, along with increasing the options of choice. In order for the AccP to contribute to the development of medical education, accrediting agencies and medical schools must first be recognized as part of an "educational alliance" working together towards common goals. Secondly, clear guidelines on the accreditation standards should be periodically reviewed and shared. Finally, a formative evaluation using self-evaluation as a system that can utilize the AccP as an opportunity to develop medical education must be introduced. This type of evaluation system could be developed through collaboration among medical schools, academic societies for medical education, and the accrediting authority.

• Journal of the Korean Society of Industry Convergence
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• v.27 no.3
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• pp.509-517
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• 2024

Purpose : The study examined the knowledge and health education about first aid of college students. Methods : The survey had done from October to December, 2022. Total subjects in this study were 205. The collected data were analyzed by SPSS 24.0 program. Results : Regarding the difference in first aid knowledge according to the first aid education characteristics of the subjects, significant differences were observed in experience of first aid training (t=6.54, p(.01), necessity of first aid training (t=3.60, p(.01), and number of first aid training sessions (F=5.40, p(.01). In the case of first aid education experience, first aid education was necessary, and the knowledge score was the highest tn the three or more training sessions. As for the contents of first aid education, action tips in case of emergency, fracture, dislocation, sprain was the highest, and rescue and transport was the lowest. Conclusion : Continuous and systematic first aid education for college students is needed, and it is absolutely necessary to develop an advanced treatment education program to revitalize it.