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The Effect of protein and lipioperoxide on White Ginseng(WG) and Fermenta Ginseng(FG) Extracts on the liver in Mice that was irradiated by radiation (방사선이 조사된 생쥐 간에서 백삼과 발효인삼추출물이 단백질 및 지질과산화에 미치는 효과)

  • Ko, In-Ho;Chang, Chae-Chul;Koh, Jeong-Sam
    • Journal of radiological science and technology
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    • v.27 no.3
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    • pp.43-50
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    • 2004
  • The effects of ginseng extracts on liver damage induced by high energy x-ray were studied. To one group of ICR male mice were given white(50 mg/kg/day for 7 days, orally) and fermenta ginseng extracts(500 mg/kg/day for 7 days, orally)before irrdiation. To another group were irradiated by 5 Gy dose of high energy x-ray. Contrast group were given with saline(0.1 ml). This study also investigated the effect between MDA, protein content and ginseng extracts on hepatic damage. This study measured the level of MDA(malondialdehyde), protein content in liver tissue. Administrating orally white (50 mg/kg/day for 7 days, orally)and fermenta ginseng extracts(500 mg/kg/day), the level of MDA were generally decreased and the inhibition was increased. And the protein contents were identical with control group. After irradiation, the protein contents were increased and MDA(malondialdehyde) was increased. Therefore, ginseng extracts increased antioxidative enzyme activity. And We know that the antioxidatant effect of extracts from white and fermenta ginseng protect radiation damage by direct antioxidant effect involving SOD, CAT, GPX. It was included that ginsengs can protect against the lipid peroxidation in radiation damage through its antioxidatant properties.

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Blood Picture of the Korean Native Goats from Birth to Maturity (한국 재래 염소의 성장에 따르는 혈액상의 변동)

  • Choi, Hi In
    • Korean Journal of Veterinary Research
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    • v.14 no.1
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    • pp.115-133
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    • 1974
  • Although considerable research has been done on the changes associated with age in the blood picture of domestic and laboratory animals, little work has been made of the changes occurring at different age in the blood picture of goats. And a comprehensive survey of the bood picture of Korean native goats has not been made. The object of the present investigation was to suggest standards for the blood picture of Korean native goats at frequent intervals from birth to maturity. The goats were kept under average farming conditions in this country. Observations were made at the following ages: at birth; 2,4 and 7 days; 2, 3, 4, 5, 6, 7, 8 and 9 weeks; 2.5, 3,6 and 12 months. Blood samples were drawn from the jugular vein. It was taken between 8 and 9 a.m. except those for the at-birth period. Erythrocyte and leukocyte enumerations and, determinations of hemoglobin in blood and hematocrit value were made in the usual manner. Reticulocytes were enumerated per 1,000 erythrocytes in blood smears stained with briIliant cresyl blue and counterstained with Wright's stain. Erythrocytes counts declined from $8.7{\times}10^8/mm^3$ at birth to a low of 7.0 at 4 days of age. These values increased to 11.5 at 5 weeks and reached a maximum of 14.0 at 3 months of age; it then fell to 11.5 at 12 months of age. Concentrations of hemoglobin in blood and hematocrit values were not related to the changes of erythrocyte counts. The values at birth were higher than at any other period during the first year of life. These fell from highs of 12.3 g/100 ml and 38.0 ml/100 ml to lows of 9.2 and 29 at 4 weeks for concentration of hemoglobin in blood and hematocrit value, respectively. There was a common pattern for the hematocrit value and hemoglobin in blood which showed three phases-a fall during the first month, a rise to the third month, and a fall to the mature level at 12 months of age. Mean corpuscular volume and mean corpuscular hemoglobin showed a common pattern. The values were $44.2{\mu}m^3$ and 14.2 pg at birth and fell, at first slowly and then rapidly, to reach adult levels of 24.1 and 7.9 at 6 weeks of age for mean corpuscular volume and mean corpuscular hemoglobin, respectively. Mean corpuscular hemoglobin concentration was little affected by age. Reticulocyte was observed from birth to 4 weeks of age. Percentage of reticulocyte decreased from 0.85% at birth to 0.06% at 4 weeks of age. Total leucocyte counts increased from $5.64{\times}10^3/mm^3$ at birth to a maximum of 13.4 at 3 months; it then fell to 11.5 at 12 months of age. In differential counts myelocyte, juvenile and band form decreased with advancing age. No myelocyte and juvenile were seen after the age of 7 and 9 weeks, respectively, and band forms were rare after the age of 3 months. Percentage of mature neutrophil showed a quick decline from 52.5% at birth to reach a minimum level (34.5%) at 3 months of age; it then rose to 38% at 12 months of age. Percentage of lymphocyte increased from 39.2% at birth to maximum of 59% at 3 month of age; it then fell to 54.9% at 12 months of age. Percentage of monocyte was not affected with advance of age. Percentage of eosinophil and basophil were increased with advance of age to reach a maximum at 2 to 3 month of age. It then fell to adult level at 12 month of age.

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Weedy Control Efficacy and Injury of Rice Plant by Golden Apple Snail(Pomacea canaliculata) in Environment-friendly Rice Paddy Fields (벼 친환경재배에서 왕우렁이의 잡초방제효과 및 피해)

  • Kwon, Oh-Do;Park, Heung-Gyu;An, Kyu-Nam;Lee, Yeen;Shin, Seo-Ho;Shin, Gil-Ho;Shin, Hae-Ryoung;Kuk, Yong-In
    • Korean Journal of Weed Science
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    • v.30 no.3
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    • pp.282-290
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    • 2010
  • The objective of this research was to discover the best method for weed management in environment-friendly rice paddy fields through the study on the effect of weed control and injury levels of rice plants as affected by size, input time, and input amount of golden apple snail (GAS). The efficacy of weed control as affected by GAS when applied at 5, 10, and 15 days after transplanting (DAT) was 98, 89, and 58%, respectively. The efficacy of weed control had declined as late the input time of GAS. On the other hand, the efficacy of weed control as affected by rice bran followed by GAS treatment was higher than by GAS treatment alone. Weed species such as Persicaria hydropiper, Echinochloa crus-galli, Scirpus juncoides, and Monochoria vaginalis were not completely controlled by GAS when applied late. Input amount and time of adult GAS (70 days after hatching) for effective weed control were 3 kg $10a^{-1}$ at 5 DAT, 6-7 kg $10a^{-1}$ at 10 DAT, and 7 kg $10a^{-1}$ at 15 DAT. Input time and amount of young GAS (35 days after hatching) for effective weed control were 0 day after harrow (DAH) and 1 kg $10a^{-1}$, respectively. The young GAS when applied 0 DAH at 1 kg $10a^{-1}$ provided 100% control of P. hydropiper, E. crus-galli, S. juncoides, M. vaginalis, Ludwigia prostrata, Eleocharis kuroguwai, Sagittaria trifolia and Cyperus difformis. The rice foliar injury caused by adult (3 kg $10a^{-1}$) and young (1 kg $10a^{-1}$) GAS were 5-7% and 1% respectively. There was no significant difference in rice injury by size and input amount of GAS on plant height and number of tiller. These data indicate that the young GAS when applied 1 kg $10a^{-1}$ at 0 day after harrow was the best method for weed management in environment-friendly rice paddy fields.

Effect of Various Organic Materials on Weed Control in Environment-friendly Rice Paddy Fields (벼 친환경재배에서 다양한 유기자원별 잡초방제효과)

  • Kwon, Oh-Do;Park, Heung-Gyu;An, Kyu-Nam;Lee, Yeen;Shin, Seo-Ho;Shin, Gil-Ho;Shin, Hae-Ryoung;Kuk, Yong-In
    • Korean Journal of Weed Science
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    • v.30 no.3
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    • pp.272-281
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    • 2010
  • The objective of this research was to find out the weed management techniques in environment-friendly rice paddy fields through the study on herbicidal effects and problems of various organic materials. This experiment was conducted under different conditions of weed species and weed densities in environment-friendly rice paddy fields. There was no difference in weedy efficacy on golden apple snail (GAS), paper mulching (PM), and machine weeding (MW) between low and high weed densities. However, the effect of weed control in rice bran (RB) and effective microorganism (EM) + molasses was higher in high weed density than in low weed density. In general, the effect of weed control as affected by various organic materials was in the order of GAS (97-100%) > PM (93-98%) > RB (15-80%) > EM (7-31%). GAS provided excellent control of all weed species tested except for Persicaria hydropiper. PM gave acceptable control of the weed species except for Echinochloa crus-galli, Ludwigia prostrata, and Eleocharis kuroguwai. However, MW gave fair control (70% biomass reduction) of all weed species tested. BR followed by MW or EM followed by MW treatments had similar effect on weed control compared to each treatment alone. However, BR followed by GAS or EM followed by GAS provided 100% control of weed species tested. The level of rice foliar injury caused by various organic materials was in the order of GAS and MW (10-20%) > RB (10-15%) > PM and EM (5-7%). Typical symptoms of organic materials are wilting, inhibition of growth, missing hill, and reduction of tiller. Cost for weed control of GAS, RB, EM, and PM were 2.1, 3.1, 2.3, and 13.2 times higher than that of the herbicide. These data indicate that GAS was the best method for weed management in environmentfriendly rice paddy fields. Further study is required to elucidate the mechanisms underlying the rice injury as affected by GAS.

Acute Oral Toxicity and Anti-obesity Effect of Diglyceride Preparation Containing Conjugated Linoleic Acid in Rat (공액리놀레산 함유 디글리세라이드 식용유지 조성물의 rat에 대한 단회 경구투여독성 및 항비만 효과)

  • Hong, Soon-Gi;Park, Chae-Kyu;Lee, Mi-Ja;Chung, Shin-Gyo;Lee, Young-Ho;Hyun, Sun-Hee
    • Korean Journal of Food Science and Technology
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    • v.41 no.3
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    • pp.320-325
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    • 2009
  • The present study was carried out to investigate the acute oral toxicity and anti-obesity effects of a diglyceride preparation containing conjugated linoleic acid (DG+CLA). To test its acute oral toxicity, the DG+CLA was injected into 30 rats (15 males and 15 females) at dosage of 2,000 mg/kg and 5,000 mg/kg. Mortality rates, clinical signs, and body weight changes were monitored for 14 days following administration. According to the results, the lethal dose ($LD_50$) of DG+CLA was determined as >5,000 mg/kg in both sexes. There were no significant changes in general conditions, clinical signs, body weight, and gross lesions between the vehicle control and DG+CLA groups. For the anti-obesity studies, obese Zucker rats were randomly divided into 4 groups and fed saline, soybean oil, diglyceride, and DG+CLA, respectively, for 8 weeks. The DG+CLA groups presented significant differences in body weight, food efficiency ratio, serum lipid levels, and fat weight. Overall, the results showed that the DG+CLA did not have acute oral toxicity and reduced body weight, serum lipid levels, and fat gain.

Monitoring Bacillus cereus and Aerobic Bacteria in Raw Infant Formula and Microbial Quality Control during Manufacturing (영.유아용 식품원료의 Bacillus cereus와 일반세균 모니터링 및 제조공정 중 미생물 품질제어)

  • Jung, Woo-Young;Eom, Joon-Ho;Kim, Byeong-Jo;Ju, In-Sun;Kim, Chang-Soo;Kim, Mi-Ra;Byun, Jung-A;Park, You-Gyoung;Son, Sang-Hyuck;Lee, Eun-Mi;Jung, Rae-Seok;Na, Mi-Ae;Yuk, Dong-Yeon;Gang, Ji-Yeon;Heo, Ok-Sun;Yoon, Min-Ho
    • Korean Journal of Food Science and Technology
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    • v.42 no.4
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    • pp.494-501
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    • 2010
  • The purpose of this study was to examine the presence of Bacillus cereus, aerobic bacteria and coliforms in the raw material of infant formulas and investigate the manufacturing process in terms of microbial safety. Among ten kinds of raw infant formula material samples (n=20), Bacillus cereus appeared in two (n=4). Aerobic bacteria were not detected in raw infant formula material or maximum 4.15 log CFU/g. Eleven species of aerobic bacteria were isolated and 76% of them were Sphingomonas paucimobilis, Pseudomonas fluorescens, Rhizobium radiobactor, or Stenotrophomonas maltophilia. A Pearson's correlation analysis revealed that the most influential factors for detecting Bacillus cereus were aerobic bacteria and coliforms. In other words, when the measured values of aerobic bacteria and coliforms were higher, the possibility that Bacillus cereus would appear increased. In a regression model to predict Bacillus cereus, the rate of appearance was correlated with aerobic bacteria and coliforms, and its contribution rate for effectiveness was 86%. Improving microbial quality control by pasteurization, spray dry, popping and extrusion resulted in a decrease in the numbers of Bacillus cereus, aerobic bacteria and coliforms in the raw materials. The results suggest that a hazard analysis and critical control point system might be effective for reducing microbiological contamination.

Types of Perception toward End-of-Life Medical Decision-making of Clinical Nurses: Q-Methodological Approach (말기환자의 의료적 의사결정에 관한 임상간호사의 인식: Q 방법론적 접근)

  • Jo, Kae-Hwa;Kim, Yeon-Ja;Sohn, Ki-Cheul
    • Journal of Hospice and Palliative Care
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    • v.15 no.1
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    • pp.18-29
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    • 2012
  • Purpose: We analyzed how clinical nurses in Korea perceive terminally ill patients' medical decision-making. Methods: The Q-methodology which analyzes the subjectivity of each item was used. We selected 34 Q-statements among those provided by each of 37 subjects and grouped them into a shape of normal distribution using a 9 point scale. The collected data were analyzed using a QUANL PC program. Results: Four types of perception toward medical decision-making were identified. Type I focuses on patient participation, and Type II emphasizes the role of health professionals. Type III is characterized by an open-minded culture toward death, and Type IV values the role of family members. Conclusion: The results of this study indicate the need for development of a multi-disciplinary curriculum medical decision-making and death for medical and nursing students.

Growth of the Korean Public Library from the Point View of Acculturation (문화변용이론의 시각에서 본 우리나라 공공도서관의 발전과정)

  • Chun Myung Sook
    • Journal of the Korean Society for Library and Information Science
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    • v.10
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    • pp.39-70
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    • 1983
  • The concept of the public library defined by the Korean Library Association does not describe the current state of the Korean public library but describes the public libraries in the western society. Korean public library was formed after the western public library but it was modified and reconciled with the tradition of Korea. The difference between the concepts occured in the acculturation process of the Korean public library. According to the International Encyclopeadia of the Social Sciences, acculturation comprehends those phenomena which result when groups of individuals having different cultures come into continuous firsthand contact, with subsequent changes in the original cultural patterns of either of both groups. Korea opened its door to western world in 1876, and it began to contact with the western world. As the consequence, the concept of the public library of the West diffused to Lee Dynasty which were characterized by the confucianism and the extended family system. These two characteristics were against the public library concept and it could not function as it was and it had to be modified to fit to Korean society. The American public library was formed by the diffusion of English public library. The concept fitted in the colonial American society which was characterized by the Christianity and nuclear family system. Religion and family life were closely knitted together and they contributed much to the formation of the American public library. Also the society needed various information to form their new nation. The need of the public library grew and the public library repidly developed as the American society was urbanized and industrialized. The changes of Korean public library has passed the following process of acculturation. 1. The Korean culture contacted with Western world. 2. The public library concept diffused to Korea, but the people were illiterate and the need of the public library was for the preservation of the old books. The collection was not for people. 3. The function of the public library in Korea was altered slightly as several intellectuals who formed the first modern public library tried to literate Koreans as a means of liberation :from Japan through the library service. 4. The traditional libraries such as sodandg and hyangyo disorganized and finally disappeared as the traditional elements of the culture disappeared and the new cultural elements prevailed in Korea. 5. When the traditional elements of culture were disorganized, a reinterpretation of the diffused culture appeared. With the appearance of the vouth group which was not existed in the traditional society, cultural facilities for them were needed. They began to use public library as their reading rooms. This pattern has been institutionalized ever since in Korean public library. 6. When the new element of the culture spread, the traditional cultural elements react against this element. As the new public libraries sprung out, there were movements to restore the old Korean tradition of the family libraries and Hyangyo to counteract to the new libraries. This movements were not successful and they all disappeared as they could not keep up the rapid social change occurred in the Korean society. 7. In the process of the cultral change, cultural lag occurred between the public library and the users who could not adopt to the new library. This has been continued to the present time. 8. This diffused concept of the public library was modified and became native to Korean society. However, the acculturation of the public library concept has not changed the traditional ideas of Korean people and their behavior. The Korean society recently has been changing rapidly and the function of the Korean public library is improving accordingly; 1. The extended Korean family system is disorganizing. As the consequence, the public library could substitute the family system offering information and recreation service, etc. 2. The growth of educated population is requiring a variety of library materials. An individual library can not meet the needs of them and cooperative library service will be needed to share resources. The public library will become the center of the cooperative service. 3. The Koreans are watching TV more hours than they read printed materials. For them, the public library needs to collect audiovisual materials. Especially the teaching materials should be all audiovisualized for the effective teaching. 4. Technology is developing rapidly in Korea, especially computer technology is applied in many parts of the society. This will also influence library service. The public library will be developing as the centralized library computer system. When the Korean public library functions as the extended family system and the center of the cooperative library system, the Korean public library will be functioning as the public library defined by the Korean Library Association.

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Epidemiologic Study of Zoophilic Dermatophytoses between 2010 and 2016 (2010~2016년 동안 동물친화성 피부 사상균 감염의 역학적 연구)

  • Kim, Su Jung
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.439-445
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    • 2017
  • In recent years, change in life patterns gave rise to an increase in the number of families with companion animals, and as a result, frequent dermatophytes infections have been reported. Microsporum canis, Trichophyton mentagrophytes, and Trichophyton verrucosum, are among these species of zoophilic dermatophytes. Trichophyton mentagrophytes are transmitted to humans by contact with wild animals. Infection from it causes strong inflammation in humans. Conversely, Trichophyton verrucosum is transmitted by contact with cattles. Microsporum canis will become latent carriers in cats or dogs, causing infectious diseases when it comes in contact with humans. We investigated zoophilic dermatophytes isolated according to annual, sex, age, season, body sites, and clinical types between 2010 and 2016. According to our results, the isolation rate of zoophilic dermatophytes was 0.37%, among which, 88 T. mentagrophytes, 228 Microsporum canis, and 18 Trichophyton verrucosum were isolated in human. It is interesting to note that Microsporum canis has been on the rise since 2014. Microsporum canis and Trichophyton verrucosum were highly isolated in females, but T. mentagrophytes was isolated similarly in both sexes. According to an age-based survey, the isolation rate was higher in children younger than 10 years. Our results is a valuable data for predicting and studying the isolation of zoophilic dermatophytes in the future.

Effect of Seeding Date and Fall Harvest Method on the Growth Charateristics , Forage Yield and Quality of Winter Rye (파종시기 및 가을 수확방법이 추파호밀의 생육특성 , 사초수량 및 사료가치에 미치는 영향)

  • 김종덕;김동암
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.14 no.3
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    • pp.238-246
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    • 1994
  • This experiment was carried out to determine the effects of seeding date and fall harvest method on the growth characteristics, forage yield and quality of winter rye(Seca1e cereale L.) at the forage experimental field, College of Agriculture and Life Sciences, SNU, Suweon from 5 September 1992 to 21 May 1993. The experiment was arranged in a split plot design with three replications. Main plots consisted of three harvests, no defoliation, cutting and grazing. Sub-plots consisted of seeding dates, early(5 September), mid(25 September) and late(l0 October). The results obtained are summari7d as follows; I . A 3-day difference in the first heading of rye was observed between no defoliation and fall grazing, while there was a 6day difference between early and late seeding dates. Therefore, the effect of seeding dates on the fist heading date of rye was larger than that of fall harvest methods. 2. CP content of rye with fall grazing was slightly higher averaged 16.5% compared with both fall cutting and no defoliated 1ye(15.6%). Mean CP content of rye at the early, mid and late seeding dates was 14.2, 14.5 and 19.1 %, respectively. 3. ADF content of rye was slightly higher with both fall cutting(29.99) and no defoliation(29.5%) than that of fall grazing(28.0%). ADF content of rye at the early, mid and late seeding dates was 30.7, 29.1 and 27.7%, respectively. Effect of fall harvest methods and seeding dates on NDF content of rye were similar to the observations made on ADF. 4. RFV and IVDMD of rye were lower with both no defoliation and fall cutting than fall grazing. but those of rye slightly increased with seeding dates progressed. 5. Dry matter yield of rye was the highest of 6,779 kg/ha with fall cutting, while the lowest yield of 6,240 kg/ha was obtained from no defoliation But no significant difference was found among the harvest methods. Dry matter yield of rye was significantly declined with later seedings. It is concluded that the highest forage yield of rye be possible from two harvest systems of fall and spring with earlier seeding rather than from one harvest system of spring.

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