Purpose : Cuscuta chinensis Lam. is utilized extensively as important medicines for threatened abortion habitual abortion. However, objective data related to an embryo is not existed until now. Therefore, this study is focused to find out stability of Cuscuta chinensis Lam. about an embryo during pregnancy based on data related to stability of nerve cell and antioxydative effect by using neural cell line, PC 12 cell. Methods : Experimentation concerns cytotoxic effects and antioxydative effect through methods such as MTT ssay, western botting after abstracting an undiluted solution from domestic Cuscuta chinensis Lam. Results : 1. As a result of experimentation on MTT assay according to each magnification from Cuscuta chinensis Lam. extraction solution with different abstraction methods, cytotoxic effect is not observed to all extract except an undiluted solution which is abstracted from MeOH stiring. Also, an undiluted solution in stiring with MeOH could not confirm whether come from Cuscuta chinensis Lam. or not. 2. As a result of revelation of Bax and GSK-3${\beta}$ which is responsive to the first stage from general stress in order to observe antioxydative effects of Cuscuta chinensis Lam. revelation of Bax by Cuscuta chinensis Lam. appeared to decrease. Conclusion : Cytotoxic effects with Cuscuta chinensis Lam. about PC12 cell is not discovered and it assume that it would be anti apoptotic effect by ROS as Bax and GSK-3${\beta}$ inviable effect. In the future, this study could be used as basic data for additional research on Cuscuta chinensis Lam. and effect and stability of complicated prescriptions for keeping pregnancy.
Purpose: Chronic ankle instability is a very common abnormality of the ankle, but there is still controversy regarding its evaluation criteria. The stress view has difficulties in reflecting the patient's symptoms and treatment progress. Therefore, this study examined the relationship between the center of pressure (COP) measured by a pedobarograph and the symptoms of the patient. Materials and Methods: Thirty patients with chronic ankle instability from February to August 2018 were included. Each patient was surveyed with the foot and ankle outcome score (FAOS). The COP was measured with a foot pressure scanner, and the travel distance and ellipse area of the COP were calculated. Each patient was measured on one foot and on two feet with his or her eyes closed and open. The relationship between the COP measurement and FAOS score was analyzed using the Pearson correlation coefficient. Results: The participants were consisted of 21 male and nine female, with a mean age of 30 years, mean weight of 72 kg, and mean foot size of 259 mm. With the eyes open, the correlation coefficient between the FAOS and travel distance of the affected side was -0.394 (p<0.05) and that between the FAOS and the ellipse area of the affected side was -0.425 (p<0.05). On the other hand, no significant correlations were found between the travel distance and ellipse area of the affected side when patients closed their eyes. Conclusion: Measurement of the COP using foot pressure scanner could evaluate objectively patients with chronic ankle instability, with measurements in patients with their eyes open being more significant. Based on the findings of this study, an analysis of the COP with the patients with their eyes open and standing on one foot may help determine the management strategy and assess the progress of the patients.
The purpose of this study was to identify the factors influencing health promoting lifestyle of teachers and to provide the data for efficient health management of teachers. The subjects of this study were eight hundred nine teachers, who were chosen in Choong-Buk province. Survey Questionaires for data analysis were collected through visiting or mailing from September 1 to 30, 1997. The instruments used in this study were HPLP(Health Promoting Lifestyle Profile) by Walker (1987), Internal Health Locus of Control by Walston et al. (1978), Self Esteem by Rogenberg(1965), Importance of Health by Muhlenkamp (1985), Self Efficacy by Sherer & Maddux(1982), and Family Function by Olson & Schellenberg (1985). Data were analyzed by descriptive statistics, unpaired t-test, ANOVA, Pearsons correlation coefficient and stepwise multiple regression using SPSS/PC(v. 4.01) program. The results were as follows; 1. The mean of health promoting lifestyle was total 2.53 on the average, self-actualization 2.97, nutrition 2.90, interpers 52, stress management 2.33, exercise 1.91, and health responsibility 1.82 in order. The index of total health promoting lifestyle was significantly influenced by the factors including sex, age, religion, marital status, duration of work, teaching load, education level and number of family members. 2. The health promoting Lifestyle was significantly positive correlated with Self Efficacy, Family Function, Importance of Health, Internal Health Locus of Control and Self Esteem. 3. Self Efficacy was the most influential determinant predicting health promoting lifestyle of teachers. Self efficacy, Family Function, Importance of Health, Internal Health Locus of Control and Age explained 42% of the health promoting lifestyle. Based on the above findings, it is suggested to develop nursing intervention to improve Self Efficacy, Importance of Health, Family Function of teachers enhance health promoting lifestyle. Further studies are needed to confirm these findings and to determine factors which significantly influence health promoting lifestyle of teachers.
Kim, Sung Chan;Ryu, Cheolho;Lee, Jang Hyun;Lee, Kyung Seok
Journal of Advanced Research in Ocean Engineering
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제2권3호
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pp.150-157
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2016
When blocks are supported on a dock, huge reaction forces concentrated at the supports cause structural damage owing to local stress concentrations. Thus, the supports should be arranged to avoid local failure from the reaction forces by redistributing those forces. Docking analyses to determine the proper blocks and their support arrangements are introduced so that the local stresses are minimized to warrant the safety of the docking supports. Local stresses enforced by the support arrangement should be evaluated by finite element analysis (FEA). However, it is difficult to consider an accurate 3D geometry of the blocks in the finite element model because the structural design information is too complicated to determine within several days using the FEA model. This paper presents a simplified FE model to evaluate the safety of the arrangement of supports using a simplified grillage element. The grillage element can be efficiently used to obrain the reaction forces in docking analysis becasuse the reaction forces at the supports are enough to assess the safety of block. Since a simplified grillage model of the entire ship cannot accurately calculate the local stresses, an optimized modeling method based on the grillage element was introduced. The local reaction forces obtained by the proposed approach and three-dimensional FEA were discussed for typical types of ships. It is shown that the reaction forces obtained by the present grillage model are in reasonably good agreement with the FEA model.
Objectives : As a part of plan to develop evidence-based treatment guidelines for depression that is more suitable for Korean situation, we investigate the present status and client's requirements for non-pharmacological treatment of depression in Korean clinical situation. Methods : Subjects were patients with depression in 12 university hospitals which are located in metropolises in Korea. We analyzed the records from questionnaires about current clinical status and requirements for the non-pharmacological treatment of depression in Korea. Results : 50.8% of the subjects have experienced non-pharmacological treatments for their depression. The preference of non-pharmacological treatment method of depression is exercise/interesting activity, counseling by psychiatrists and psychotherapy, and the best effective treatment method is psychotherapy (Es=4.36). Actually, the mean consultation time by psychiatrist is $11.31{\pm}7.16$ min, and the appropriate consultation time for client's situation is $18.39{\pm}8.95$ min. During consultation, patients' satisfaction measurement for psychiatrist's explanation about pharmacological treatment is $64.17{\pm}27.11$, and satisfaction measurement for psychiatrist's counseling for their depression about personal problems, resent stress, interpersonal relationship is $61.66{\pm}26.63$. Conclusion : In Korea, many psychiatrists offered biologically oriented treatment to their patients with depression, and patients' satisfaction measurement about consultation by psychiatrists is low. Many patients wanted to combined pharmacological and non-pharmacological treatment for their depression, and aspired to information about complementary and self-help treatment methods. It is necessary to develop non-pharmacological treatment guideline for depression which reflect the clinical situation in Korea and meet Korean patients' need.
I got the following result from the bibliographic study about the meaning of Hwa(火) and Hwa- byung(火病) at the concept and the aspect of pathological and etiological factors.The results are as follows.1. The pathological characteristics of Hwa(火) mean the inflammed state, the excited mental condition and perinervous hyperfunction caused by exopathy produced by any of the six extermal etiological factors(外感六淫) and Hwa caused by interior injury(內傷火熱).2. Hwa caused by the fire emotions(五志之火); anger, gladness, contemplation, sadress, fear by menta complications brings to Hwa caused by the five viscera(五臟之火) and Hwa caused by the stagnation of the liver - energy(肝鬱之火) is the rpresentive Hwa caused by the five viscera and the six hollow organs(贓腑之火).3. A symptom caused by a pathogenic Hwa(火證) is understood in a pathological sense involved an inflammed disease and is considered as a pathological state of excess syndrome(實證) caused by exterior Hwa( 外火).4. The pathologic process of Hwa-byung(火病) as the mental disease is based upon our people's emotion; Han(恨) to be pathologized without being overcome and can be considered as the process of Hwa caused by long-term(鬱久而火化).5. Hwa-byung(火病) means a psychosomatic disorder resulting from stress reaction caused by personal relations in the climacterium.Form the above mentioned study, the meaning of Hwa(火) and Hwa-byung(火病) is set theoretically and it also needs to be maintained reserching and studying about Hwa-byung(火病) consistantly.
Kim, Hye-Rim;Kwon, Soo Jeong;Roy, Swapan Kumar;Kamal, Abu Hena Mostafa;Cho, Seong-Woo;Kim, Hag Hyun;Boo, Hee Ock;Cho, Kab Yeon;Woo, Sun-Hee
한국작물학회:학술대회논문집
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한국작물학회 2017년도 9th Asian Crop Science Association conference
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pp.131-131
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2017
Though the Platycodon grandiflorum, has a broad range of pharmacologic properties, but the mechanisms underlying these effects remain unclear. In order to profile proteins from the nodal segment, callus, root and shoot, high throughput proteome approach was executed in the present study. Two-dimensional gels stained with CBB, a total of 84 differential expressed proteins were confirmed out of 839 protein spots using image analysis by Progenesis SameSpot software. Out of total differential expressed spots, 58 differential expressed protein spots (${\geq}2-fold$) were analyzed using MASCOT search engine according to the similarity of sequences with previously characterized proteins along with the UniProt database. Out of 58 differential expressed protein, 32 protein spots were up-regulated such as ribulose-1,5-bisphosphate carboxylase, endoplasmic oxidoreductin-1, heat stress transcription factor A3, RNA pseudourine synthase 4, cysteine proteinase, GntR family transcriptional regulator, E3 xyloglucan 6-xylosyltransferase, while 26 differential protein spots were down-regulated such as L-ascorbate oxidase precursor, late embryogenesis abundant protein D-34, putative SCO1 protein, oxygen-evolving enhancer protein 3. However, the frequency distribution of identified proteins using iProClass databases, and assignment by function based on gene ontology revealed that the identified proteins from the explants were mainly associated with the nucleic acid binding (17%), transferase activity (14%) and ion binding (12%). Taken together, the protein profile may provide insight clues for better understanding the characteristics of proteins and its metabolic activities in various explants of this essential medicinal plant P. grandiflorum.
The purpose of this study was to identify the frequency of Urinary Incontinence and lower urinary tract symptoms, to identify life style problems for UI of Women in anIsland. The sample consisted of 88 women in an island, a urinary symptom questionnaire developed by Jackson, et. al. and a demographic questionnaire were used to collect the data. The results of study were as following. 1. It was reported that the subjects have experienced UI and various lower urinary symptoms such as stress incontinence, nocturia, intermittency, abnormal stream, feeling of incomplete emptying and also they have experienced some degree of 'bother' 2. It was reported that the subjects have experienced various life style problems for UI 3. There was significant relationship between age and urgency (p=0.0262), bladder pain (p=0.0268), abnormal strength of stream (p=0.0074), inability to stop midstream (p=0.0026), and ability to perform daily tasks (p=0.0488), 4. There was a significant relationship between the number of discharges and urgency (p=0.0273), abnormal strength of stream (p=0.0307), and inability to stop midstream (p=0.0122). 5. There was a significant relationship between menopause and bladder pain (p=0.0020), abnormal strength of stream (p=0.0245), and inability to stop midstream (p=0.0002). 6. There was a significant relationship between the degree of experiences for lower urinary tract symptoms and life style behavior. Therefore, based on the results, a developing and carrying out of adequate UI care program is needed.
Objectives : In this paper, lung atrophy syndrome[肺痿] in 『Huangdineijin(黃帝內經)』 and 『Jinguiyaolue(金匱要略)』 were compared, followed by examining its relation with upper wasting thirst[上消]. Also, ways in which psychological factors that contribute to lung atrophy syndrome could cause upper wasting thirst were studied. Methods : Verses from 『金匱要略·肺痿肺癰咳嗽上氣病脈證治』 and 『素問·痿論』 were analyzed based on various annotators's opinions to determine the cause and mechanism of lung atrophy syndrome and its relationship with upper wasting thirst. Results : In 『Jinguiyaolue(金匱要略)』, lung atrophy syndrome is described as the heat of the upper body entering the lungs to dry it out. The description in 『Suwen(素問)』 differs in that it accompanies atrophy symptoms, but the mechanism is the same. Lung atrophy syndrome in 『Jinguiyaolue』 could come from wasting thirst, while wasting thirst can be accompanied in deficiency caused by chronic lung atrophy syndrome. Heat in the lungs is caused by psychological factors where the person has lost its subject of possession or was unable to attain what was desired. When expanded to include heart atrophy syndrome[心痿] and lung atrophy syndrome[肝痿], the reason for upper wasting thirst could include immense sadness or excessive indulgence in pleasure due to unmet desires. Conclusions : Although diabetes and wasting thirst are not identical, application of wasting thirst pattern differentiation to diabetes treatment and management could lead to tailored treatment of each patient. Moreover, the five zhang pattern differentiation from the 『Suwen(素問)』 could increase treatment efficacy when applied to conditions caused by stress and emotional disorder, which are increasingly playing larger roles in causing wasting thirst, or diabetes.
The purpose of this study was to identify the observable symptoms of musculoskeletal disease from electronic components manufacturing workers who involved in many repetitive tasks and to provide the basic data for the prevention and management. The survey was conducted on 721 people from 15 April, 2013 to 17 May, 2013 by selfrecording type. The results of the study are as follows. First, symptom complaints based on different body parts are in following order, waist was 12.9%, shoulder was 10.5%, neck was 7.4%, hand/wrist/finger was 7.4%, leg/foot was 4.4%, arm/elbow was 2.8%, and 21.9% of the respondents showed symptoms in more than one body part. Sex, age, marital status, work experience, work intensity, and past accident experience were statistically significant. Second, in the job stress evaluation, all male and female workers were below the median of Korean workers in all of 8 categories. the higher the scores for lack of job autonomy, the higher the symptom complaints of musculoskeletal disease. In the case of patients complain observable symptoms of musculorskeletal disease, they should receive proper outpatient treatment, various programs such as stretching by body parts, setting up a desirable working posture, switching to cyclical work, should b developed as much as possible.
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