• Anxiety and mood
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• v.2 no.1
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• pp.50-55
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• 2006

Objectives : In the psychiatry, structured interview is very important tool to be used in epidemiological or psychopharmacological studies. However, investigators often find that the administration of comprehensive diagnostic interviews is time-consuming and expensive to be used in clinical or research settings. Considering these points, Sheehan and his colleagues developed MINI (Mini International Neuropsychiatric Interview) to meet the need for a brief, reliable, and valid structured diagnostic interview for psychiatric disorders. The MINI has been translated into many languages and used in many countries. Therefore, we translated the MINI into Korean and determined its validity in this study. Methods : Twohundred seventy patients and normal subjects participated in the validation of the MINI versus an expert's professional opinion. Schizophrenia and other psychotic disorders, mood disorders including major depressive disorder and bipolar disorder, anxiety disorders including panic and other phobic disorders, and alcohol dependence were included in this study. The validity was obtained by examination whether MINI based diagnoses were compatible with diagnoses by expert psychiatrists. Results : The range of Kappa values was 0.22 (somatoform disorder) to 0.93 (bipolar disorder - past). Overall agreement between MINI and expert's diagnoses were good. The Kappa values for anxiety disorders seemed to be higher than those for other disorders. Conclusion : The MINI Korean version has the good validity. It also has potential applications as a diagnostic tool for psychiatric disorders.

• Korean Journal of Biological Psychiatry
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• v.14 no.1
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• pp.5-13
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• 2007

Objectives : Depression disturbs the individual life from the loss of productivity to suicide. Furthermore the whole society is also influenced by depression in social and economic areas. Many scientific treatment methods are known to be effective in depression. But in reality more than half of patients with depression prefer self help treatment rather than medically based treatment. For the patients with mild depression and primary physicians, it is reasonable to provide the evidence based self care including self help or alternative treatment. This study is supported by the Korean Health 21 R&D Project for the Depression Center to establish the Korean treatment guideline for depression. Methods : The members of Depression Center including the authors attended the workshops where the methods of evidence based medicine such as literature search, quality evaluation of the articles, making the level of evidence were educated. The professional librarians helped the authors for get the searched articles. Among the total of 354 abstracts of systemic review and 300 abstracts of random controlled trials, 3 systemic reviews and 2 random controlled trials were the main structure of evaluation. Result : Among the 37 self care methods known to be effective for depression, 11 kinds of methods were worth of evaluation. The first step for the self care of mild depression is to use St. John's wort, exercise, bibliotherapy, and light therapy in depression during winter season. Acupuncture, negative ion therapy, massage, relaxation technique are known to be efective with evidence. Music therapy, hypnotherapy, and aromatherapy are known to be effective but until now the evidences is insufficient and further evaluations are needed. Conclusion : Among 11 listed self-care methods, several methods need more evidence especially in Korean situation. Exercise is the most recommendable evidence based self care method in Korea nowadays. St. John's wort is effective with evidence, but it is not the OTC drug in Korea, so it is not recommendable now. For the bibliotherapy, there is no book such as "Feeling Good" in Korea. Only the introductory book about depression is available. Publishing the self help book based upon cognitive behavioral approach or psychodynamic approach is needed. Light therapy is practiced in a few clinics, but not self-help style. Exposure to the sunlight is recommended in the level of commen sense. These self care methods are for the mild patient. Moderate to severe patients with depression should seek the professional treatment.

• Korean Journal of Community Nutrition
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• v.15 no.1
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• pp.73-82
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• 2010

This study was conducted to investigate the effects of a weight control programs on BMI, nutrition knowledge, physical fitness and stress level of adult obese women. The subjects of this study were 36 adult obese women aged 30-65 years whose BMI were above $23\;kg/m^2$. The weight control program for obese women included nutritional education, exercise and cognitive behavioral therapy for 12 weeks. The BMI of the subjects was significantly decreased (p < 0.001) from $27.1\;kg/m^2$ to $26.4\;kg/m^2$ after the 12 weeks of the weight control program. In addition, the weight of body fat was significantly decreased (p < 0.001) and % body fat was significantly decreased (p < 0.05) from 35.4% to 34.9% after completion of the weight control program. In addition, nutritional knowledge (p < 0.001) and eating behavior scores (p < 0.01) were significantly increased. However, the food intake scores were not changed after the program. Stress levels of the adult obese women were significantly decreased (p < 0.001) from 85.63 to 66.88 and also obesity stress levels were significantly decreased (p < 0.01) after the weight control program. In the physical fitness levels of the subjects, muscle endurance (p < 0.05) and ability of balance (p < 0.01) were significantly improved after completion of the weight control program. There were positive significant correlations between general stress and obesity stress level (p < 0.05), and negative correlations between stress level and food intake score (p < 0.05). These results showed that the weight control program for adult obese women may be effectively used to improve weight reduction, physical fitness and stress levels.

• Journal of Oriental Neuropsychiatry
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• v.28 no.1
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• pp.1-13
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• 2017

Objectives: The purpose of this study is to investigate the trends in acupuncture research on Internet addiction disorder. Methods: Clinical research papers on acupuncture treatment were searched and selected. Seven databases, including English, Chinese, Japanese, and Korean databases, were searched systematically. Non-clinical, non-acupuncture, and unpublished studies were excluded. The characteristics of the included articles were described, and these articles were assessed by the Risk of Bias (RoB) tool or the Risk of Bias Assessment for Non-randomized Studies (RoBANS) tool. Results: Ten clinical studies on Internet addiction disorder were finally selected, and all of these studies were published in China. The electroacupuncture (EA) method was used in most of the acupuncture treatment studies. Most of the psychotherapy studies used cognitive behavioral therapy (CBT) in the control group. Most of the studies showed effective results. The results of this study suggest that the combination of acupuncture and psychotherapy is more effective than either treatment modality alone. However, the quality of these clinical studies was low. Conclusions: According to this study, acupuncture treatment seems to have excellent effects in Internet addiction disorder. However, the quality of most studies was low. Therefore, higher quality research on Internet addiction disorder is required.

• The Korean Journal of Pain
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• v.14 no.1
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• pp.110-113
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• 2001

In controlling chronic intractable pains, the current therapeutic methods used are exercise, over the counter medication, cognitive-behavioral therapy, opioid medication, neural blockade, operation, etc., spinal cord stimulation being the last resort. Spinal cord stimulation was initiated when Shearly and others clinically tested the Gate control theory of Melzack and Wall. This had triggered the advancement of theoretic research on the mechanism and hardware necessary and has resulted in an accumulation of clinical experiences. This is known to be effective for treating sympathetic pain, arachnoiditis, failed back pain syndrome, radiculopathy, peripheral vascular disease, phantom limb syndrome, post-herpetic neuralgia, peripheral neuropathy, and angina pectoris. This report describes our experience in experimental spinal cord stimulation in patients with simultaneous post-herpetic neuralgia and herniated intervertebral disc. There wasn't any improvement in the post-herpetic neuralgia but the symptoms of a herniated intervertebral disc was much ameliorated. This was quite an unexpected result. The patient's back pain returned when the stimulation stopped.

• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.80-80
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• 2003

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by marked cell death in the striatum and cortex. Stereotaxic injection of quinolinic acid (QA) into striatum results in a degeneration of GABAergic neurons and exhibits abnormal motor behaviors typical of the illness. The objective of this study was carried out to obtain basic information about whether parthenogenetic mouse embryonic stem (PmES) cells are suitable for cell replacement therapy of HD. To establish PmES cell lines, hybrid F1 (C57BL/6xCBA/N) mouse oocytes were treated with 7% ethanol for 5 min and cytochalasin-B for 4 hr to initiate spontaneous cleavage. Thus established PmES cells were induced to differentiate using bFGF (20ng/ml) followed by selection of neuronal precursor cells for 8 days in N2 medium. After selection, cells were expanded at the presence of bFGF (20 ng/ml) for another 6 days, then a final differentiation step in N2 medium for 7 days. To establish recipient animal models of HD, young adult mice (7 weeks age ICR mice) were lesioned unilaterally with a stereotaxic injection of QA (60 nM) into the striatum and the rotational behavior of the animals was tested using apomorphine (0.1mg/kg, IP) 7 days after the induction of lesion. Animals rotating more than 120 turns per hour were selected and the differentiated PmES cells (1$\times$10$^4$cells/ul) were implanted into striatum. Four weeks after the graft, immunohistochemical studies revealed the presence of cells reactive to anti-NeuN antibody. However, only a slight improvement of motor behavior was observed. By Nissl staining, cell mass resembling tumor was found at the graft site and near cortex which may explain the slight behavioral improvement. Detailed experiment on cell viability, differentiation and migration explanted in vivo is currently being studied.

• The Journal of the Korea Contents Association
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• v.14 no.6
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• pp.219-228
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• 2014

The purpose of this study was to determine the trends of research on the effects of psychosocial intervention related to children with epilepsy. 454 articles were retrieved from databases (Ovid-MEDLINE, EMBASE, PubMed, CINAHL, The Cochrane library, KMbase, and Koreamed), and 7 articles met our criterias. Interventions were classified into four categories: education; counseling; cognitive-behavioral therapy; and physical activity. The target outcomes of the interventions were quite diverse. Each intervention showed some benefits for epilepsy-related health outcomes, but each study had methodological weaknesses, including incomplete information, poorly defined or validated outcome measures, small sample sizes, and design limitations.

• The Journal of the Korea Contents Association
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• v.14 no.3
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• pp.269-276
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• 2014

The purpose of this study is to investigate validation of the School Function Assessment(SFA) for Korean Version using Rasch analysis. The subjects were recruited 98 students with disabilities in Seoul, Kyoung-Ki, Chung-cheung. The data were analysed using Rasch analysis to investigate unidimensionality and rating scale model. The 4 items out of SFA Part II were found to be misfts. The 18 items out of physical tasks, the 14 items out of cognitive/behavioral tasks in Part III were found to be misfit. All rating scale in SFA was appropriate. Further studies are needed to investigate validity and criterion cut-off score for many students with disabilities.

• The Journal of Korean Association of Computer Education
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• v.16 no.4
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• pp.23-31
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• 2013

The purpose of this study is to examine if educational programs to intervene with smartphone addiction developed for elementary school students are effective in reducing their smartphone overuse that has been rapidly increasing nowadays. To attain the goal, the study analyzes internet addiction intervention programs previously developed with the cognitive behavior therapy of which effectiveness has been verified in psychotherapy for those showing addiction, and based on that, it develops and applies educational programs to intervene with smartphone addiction. The conclusions the paper has drawn are as follows: First, educational programs to intervene with smartphone addiction are effective in reducing the tendencies of smartphone addiction of those students using smartphones too much for their irrational thinking or habitual behavior. Second, educational programs to intervene with smartphone addiction will facilitate behavioral changes regarding negative factors of smartphone addiction such as maladaptation in everyday life or tolerance and also help the reconstruction of elementary school students' positive cognition on smartphone use.

• The Journal of Korean Academic Society of Nursing Education
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• v.5 no.2
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• pp.206-218
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• 1999

Relapse is one of the most serious problem in alcoholism treatment area. But there is no proper post-treatment management program for preventing relapse in Korea. The purposes of this study are the analysis of several alcoholism treatment programs and recommendation about consideration for developing our alcoholism treatment program to prevent relapse in our country. Five different alcoholism treatment programs were collected for this study, two programs were collected by participant observation and three were collected by instruction manuals, references, and briefing materials. The followings are the criteria for this analysis of the five treatment programs. 1. the specific characteristics of the treatment program 2. the criterion of the patients, the duration and period (or the treatment, the special activities, and goals of the treatment. 3. the common characteristics of the five treatments. The common characteristics of those treatment programs are; 1 preparation for post-treatment from the beginning of the treatment (hospitalization) 2. assessment of relapse related factors 3. assessment of the relapse-warning signs 4. development and plan of individualized intervention strategy 5. practice of the plan The common characteristics of those treatment programs are 1. groups are classified the recovery training groups and the self-help groups 2 all kind of treatment programs carried out as groups rather than individuals. 3. usefulness which apply to various settings and various types 4. multidisciplinary and interdisciplinary approach As results, those programs were developed as post-detoxication management program, follow up program, and continued care program and their theoretical framework was from social learning theory. Those programs used the principles of cognitive-behavioral therapy for the classes, groups, and social skill training. These finding can be used for developing culturally appropriate alcoholism treatment programs focused on relapse prevention.