• Biomolecules & Therapeutics
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• v.22 no.5
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• pp.467-473
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• 2014

The purpose of this study is to investigate the memory enhancing effect and underlying molecular mechanism of arabinoxylan (AX), a major component of dietary fiber in wheat against scopolamine (SCO)-induced amnesia in Sprague-Dawley (SD) rats. Diverse behavior tests including Y-maze, Morris water maze, and passive avoidance tests were performed to measure cognitive functions. SCO significantly decreased the spontaneous alterations in Y-maze test and step-through latency in passive avoidance test, whereas increased time spent to find the hidden platform in Morris water maze test compared with the sham control group. In contrast, oral administration of AX (25 mg/kg and 50 mg/kg) effectively reversed the SCO-induced cognitive impairments in SD rats. Furthermore, AX treatment up-regulated the expression of brain-derived neurotrophic factor (BDNF) in the cortex and hippocampus via promoting activation of cAMP response element binding protein (CREB). Therefore, our findings suggest that AX can improve SCO-induced learning and memory impairment possibly through activation of CREB and up-regulation of BDNF levels, thereby exhibiting a cognition-enhancing potential.

• Journal of Digital Convergence
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• v.16 no.9
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• pp.405-412
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• 2018

When a film company decides whether to invest or not in a scenario is the appropriate time to predict box office success. In response to market demands, AI based scenario analysis service has been launched, yet the algorithm is by no means perfect. The purpose of this study is to present a prediction model of movie scenario's box office hit based on human brain processing mechanism. In order to derive patterns of visual, auditory, and cognitive stimuli on the time spectrum of box office animation hit, this study applied Weber's law and brain mechanism. The results are as follow. First, the frequency of brain stimulation in the biggest box office movies was 1.79 times greater than that in the failure movies. Second, in the box office success, the cognitive stimuli codes are spread evenly, whereas in the failure, concentrated among few intervals. Third, in the box office success movie, cognitive stimuli which have big cognition load appeared alone, whereas visual and auditory stimuli which have little cognitive load appeared simultaneously.

• Korean Journal of Cognitive Science
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• v.31 no.1
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• pp.1-23
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• 2020

This paper introduces SNUDM, an analysis program for Ratcliff's diffusion model, which has been one of the most important models in cognitive psychology over the past 35 years and which has come to occupy an important place in cognitive neuroscience in recent years. The analysis tool is designed with the basic principles of easy comprehension and simplicity in use. A diffusion process was programmed as the limit of a simple random walk in a manner resembling Ratcliff & Tuerlinckx(2002). The response time distribution of the model was constructed by simulating the time taken by a random walk until it reaches a threshold with small steps. The optimal parameter values in the model are found to be the smallest value of the chi-square values obtained by comparing the resulting distribution and the experimental data using Simplex method. For simplicity and ease of use, the input file used here is created as a file containing the quantile of the reaction time, the trials and other information. The number of participants and the number of conditions required for such work programs are given in a way that answers the question. Using this analysis tool, the experimental data of Ratcliff, Gomez, & McKoon(2004) were analyzed. We found the very similar pattern of parameter values to Ratcliff et al.(2004) found. When comparing DMAT, fast-dm and SNUDM with the generated data, we found that when the number of trials is small, SNUDM estimates the boundary parameter to a value similar to fast-dm and less than the DMAT. In addition, when the number of trials was large, it was confirmed that all three tools estimate parameters similarly.

• Journal of Korean Academy of Nursing
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• v.13 no.2
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• pp.1-21
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• 1983

The purposes of this study were to(a) develop theoretical modifications of the extended gate control theory of pain using Fishbein's model and（b) test the efficacy of these modifications. Attitude, social subjective norm, personal subjective norm, habit and state anxiety were operationalized to represent internal stimuli for the cognitive-evaluative and motivational-affective dimensions of the theory. Pain expression was operationalized as sensory and affective responses to pain, and pain endurance. Sixty-two female nurses from 20 to 50 years of age participated. A semantic differential scale measured attitude and motivations to comply; a Likerty-type scale measured personal and social norms and habit. Spielberger's STAI measured state anxiety, Pain was produced using a modified submaximum effort tourniquet technique. Pair expression was measured using ratio scales of sensory intensity and unpleasantness developed by Gracely and his associates. Pain endurance was measured by subtracting time of pain threshold from pain tolerance. The first hypothesis examining whether pain endurance would be more significantly related to the affective response than to the sensory response was net rejected. Four remaining hypotheses, testing the ability of the five variables to predict the sensory and affective responses were not rejected. However, the habit of pain expression and the attitude toward pain expression contributed to the prediction of both sensory and affective responses to pain. The interaction between the cognitive-evaluative and the sensory-discriminative dimensions and the interaction between the cognitive-evaluative and motivational-affective dimensions were partially supported by the data from these two variables. The interaction between the motivational-affective and the sensory-discriminative dimensions was also supported by the relationship of sensory to affective responses. The variables which did not significantly predict pain expression appeared to have potential for prediction. Revision and testing of the tools for better reliability, validity, and clinical usuability are needed. The study contributed to theory building. The identification of variables which pre-dict pain behavior must occur before effective nursing interventions can be developed.

• Korean Journal of Cognitive Science
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• v.24 no.1
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• pp.1-24
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• 2013

The elderly population continues to increase in Korea and there has been a growing interest in understanding normal aging. In response to this public interest, the present paper reviewed human aging research focusing on recently published neuroimaging studies. For the first half of the paper, I reviewed the effects of aging on the brain and cognition. In normal aging, structural changes in the brain include atrophy and volume reduction in the prefrontal and temporal cortices. Functional changes are exhibited in the form of overactivation of the brain. Moreover, age-related cognitive decline is particularly observed in inhibition and memory, which are also associated with the age-related structural changes in the brain. For the second half of the paper, I introduced physical exercise studies showing that exercise played a protective role in the age-related neurocognitive decline. More specifically, engaging in physical exercise (particularly, aerobic exercise) for a relatively long period of time (e. g., > 6 mon.) protected older adults from volume loss in the prefrontal cortex and the hippocampus, and induced better inhibition and memory. These exercise-induced benefits appear to be associated with changes in neuronal levels, indicating that the aging brain is still plastic and this plasticity can be enhanced by physical exercise.

• Journal of the Ergonomics Society of Korea
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• v.34 no.4
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• pp.335-351
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• 2015

Objective: The aim of this study was to perform a usability test for CPAD (Cognitive Perceptual Assessment for Driving) and improve it based on the test results. Background: The cognitive perceptual assessment for driving is a computer-based assessment tool to assess the driving capacity of people with brain-damages. It may be a good tool for evaluating the brain-damaged drivers' safe driving capabilities and screening cognitive and perceptual deficits related to driving. We performed a usability test to improve the CPAD based on the result. Method: Both the software consisting of 8 sub-tests (depth perception, sustained attention, divided attention, stroop test, field dependency, digit span, trail making A, trail making B) and the hardware including the input and output devices ( joystick, mouse, keyboard, touch screen) were evaluated through user interviews. Also we identified the problems and issues in using them by observing the participants performing the CPAD tasks. Results: Based on the results, the task instructions were visually and auditorily improved and more practice examples were added to help the users understand the instructions better and increase the input accuracy, a response time window was added and the joystick and touch screen were simplified, which made it easier for the user to perform the CAPD tasks. Conclusion: User discomforts were minimized by improving the task environment, unless it had affected the evaluation criteria. Application: We plan to distribute the improved version of the CPAD to the regional rehabilitation hospitals, and the driving support centers for people with disabilities throughout the country, so it could be used as an evaluation tool for disabled drivers' cognitive and perceptual functions.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.17 no.2
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• pp.163-169
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• 2006

Objectives : The study was conducted to investigate the effect of intelligence ability on attention using Continuous Performance Test (CPT). Methods : 56 children with ADHD (52 boys, 4 girls) and 41 children in normal (28 boys, 13 girls) were sampled, their age range was 7 to 15. They performed IQ test and ADHD Diagnostic System (ADS) in order to examine intelligence and attention. Participants were divided into normal group and ADHD group, average IQ level children and superior IQ level children. Then ADS variables (omission error, commission error, reaction time, reaction time deviation, response sensitivity, and response criterion) were analyzed. Results : There was no significant interaction effect between group (normal, ADHD) and intelligence (average, superior). But there was significant difference between normal group and ADHD group in omission error, commission error, reaction time deviation, and response sensitivity. Also average level IQ group had significantly showed more omission, greater reaction time deviation, and lower response sensitivity than superior level IQ group. Conclusion : ADHD group has attention deficit than normal group, and CPT is available tool to detect attention problems. These findings indicate that intelligence can contaminate inattention and cognitive impulsivity thus it compensates for attention deficit. And it suggests that intelligence effect is considered in analyzing CPT in ADHD children.

• PNF and Movement
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• v.18 no.2
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• pp.275-286
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• 2020

Purpose: The purpose of this study is to understand and analyze the current status of dementia management and rehabilitation services in Busan, South Korea, in response to the rapid increase of people with dementia due to the aging of the population. Methods: To investigate the current status of dementia rehabilitation in Busan, a survey was disseminated to dementia safety centers and day- and night-care centers in 16 districts/counties in Busan. Of the 209 day- and night-care centers, 23 institutes were registered in the National Health Insurance Service and received the highest grade (Grade A) in the institute evaluation that was implemented in each district. A telephone interview was conducted, and survey questions were related to the existence of an ongoing dementia rehabilitation program, program presenter, number of participants, progress method, program time, program duration, program contents, and participation path. Results: Dementia safety centers were implementing dementia prevention program, cognitive enhancing program, dementia program, self-help meeting and education program for family of dementia patient. The majority of the presenters of all four dementia-related programs were occupational therapists. The highest number of participants in the dementia prevention program was 15, and the highest number of participants in the cognitive enhancing program, dementia program, self-help meeting and education program for family of dementia patient was 10. All institutes' programs delivered group therapy. As for the time and frequency of the program, most dementia program included three-hour sessions five times a week. Most dementia prevention program, cognitive enhancing program, self-help meeting and education program for family of dementia patient included 60-minute sessions once a week. The most frequently observed program duration for the dementia prevention program and cognitive enhancing program was six months, and the most frequently observed duration for the dementia program was three months. Lastly, study participants most often reported that self-help meeting and education program for family of dementia patient lasted for two months. Among day- and night-care centers in Busan, programs related to cognition were implemented in 18 institutes, and the majority of the program presenters were social workers. Conclusion: In response to the rapidly growing number of dementia patients due to the aging of the population, this study examined the current status of dementia rehabilitation in Busan. The study results underscore the need to develop systems that consider the circumstances in Busan and continuously and systematically support dementia programs.

• Korean Journal of Cognitive Science
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• v.23 no.3
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• pp.323-348
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• 2012

Three experiments were conducted to explore the interaction of personal pronoun (e.g. 'I' and 'you') and emotional evaluation (e.g. positive and negative) using time-course (e.g. SOA 500-1000ms) and multi-task approaches (e.g. lexical decision task and primed naming task). In Experiment 1, Participants were presented personal pronoun as primes at SOA 1000ms and were asked to response emotional words which were differed in emotional attributes. The results showed that the interaction effects of personal pronoun and emotional words were found. In Experiment 2, Participants were presented personal pronoun as primes at SOA 1000ms and were asked to response emotional words which were differed in emotional attributes. The results showed that no effects were found. In Experiment 3, Participants were presented personal pronoun as primes at SOA 500ms and were asked to pronounce emotional words which were differed in emotional attributes. The results showed that the interaction of personal pronoun and emotional words were found. The results of 3 experiments were discussed from a point of view of dynamic processes of social cognition.

• Journal of the Ergonomics Society of Korea
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• v.31 no.6
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• pp.785-791
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• 2012

Objective: The aim of this study was to investigate the correlation between 3D visual fatigue and physiological measures by canonical correlation analysis enabling to categorical correlation. Background: Few studies have been conducted to investigate the physiological mechanism underlying the visual fatigue caused by processing 3D information which may make the cognitive mechanism overloaded. However, even the previous studies lack validation in terms of the correlation between physiological variables and the visual fatigue. Method: 9 Female and 6 male subjects with a mean age of $22.53{\pm}2.55$ voluntarily participated in this experiment. All participants were asked to report how they felt about their health sate at after viewing 3D. In addition, Low & Hybrid measurement test(Event Related Potential, Steady-state Visual Evoked Potential) and for evaluating cognitive fatigue before and after viewing 3D were performed. The physiological signal were measured with subjective fatigue evaluation before and after in watching the 3D content. For this study suggesting categorical correlation, all measures were categorized into three sets such as included Visual Fatigue set(response time, subjective evaluation), Autonomic Nervous System set(PPG frequency, PPG amplitude, HF/LF ratio), Central Nervous System set(ERP amplitude P4, O1, O2, ERP latency P4, O1, O2, SSVEP S/N ratio P4, O1, O2). Then the correlation of three variables sets, canonical correlation analysis was conducted. Results: The results showed a significant correlation between visual fatigue and physiological measures. However, different variables of visual fatigue were highly correlated to respective HF/LF ratio and to ERP latency(O2). Conclusion: Response time was highly correlated to ERP latency(O2) while the subjective evaluation was to HF/LF ratio. Application: This study may provide the most significant variables for the quantitative evaluation of visual fatigue using HF/LF ratio and ERP latency based human performance and subjective fatigue.