• Title/Summary/Keyword: Cognitive Functions

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The Case of Vascular Dementia Treated with Gagambosim-tang(Jiajianbuxin-tang) (가감보심탕(加減補心湯) 투여 후 호전된 혈관성 치매 1례(例))

  • Cha Yong-Seok;Kim Kyong-Su;Park Byong-Min;Yun Jong-Min;Kim Yong-Jeong;Lee Seung-Eon;Lee In;Moon Byung-Soon
    • The Journal of Internal Korean Medicine
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    • v.24 no.4_2
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    • pp.1037-1045
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    • 2003
  • Objectives: Dementia is a kind of chronic, progressive, degenerative disease. The symptoms results in troubles in intellectual functions. memory, orientation, intelligence, judgement, common sense and calculating ability. The Korean version of Mini-Mental State Examination(MMSE-K) has been used widely to screen cognitive impairment of the elderly in Korea. This instrument has been specifically developed and evaluated for the assessment of cognitive function in older Korean populations. Methods: Cognitive function was evaluated by the Korean version of Mini-Mental State Examination(MMSE-K). This patient was diagnosed as Vascular dementia and We treated her cognitive impairment with Gagambosim-tang(Jiajianbuxin-tang). Results: After treated with Gagambosim-tang(Jiajianbuxin-tang), Cognitive function was improved. Conclusion: This report may have a meaning to treat Vascular dementia.

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Improvement of the Cognitive Perceptual Assessment for Driving (CPAD) based on Usability Test

  • Bae, Jae-Hyuk;Lee, Jung-Ah;Choi, Hyun;Lee, Jae-Jin
    • Journal of the Ergonomics Society of Korea
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    • v.34 no.4
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    • pp.335-351
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    • 2015
  • Objective: The aim of this study was to perform a usability test for CPAD (Cognitive Perceptual Assessment for Driving) and improve it based on the test results. Background: The cognitive perceptual assessment for driving is a computer-based assessment tool to assess the driving capacity of people with brain-damages. It may be a good tool for evaluating the brain-damaged drivers' safe driving capabilities and screening cognitive and perceptual deficits related to driving. We performed a usability test to improve the CPAD based on the result. Method: Both the software consisting of 8 sub-tests (depth perception, sustained attention, divided attention, stroop test, field dependency, digit span, trail making A, trail making B) and the hardware including the input and output devices ( joystick, mouse, keyboard, touch screen) were evaluated through user interviews. Also we identified the problems and issues in using them by observing the participants performing the CPAD tasks. Results: Based on the results, the task instructions were visually and auditorily improved and more practice examples were added to help the users understand the instructions better and increase the input accuracy, a response time window was added and the joystick and touch screen were simplified, which made it easier for the user to perform the CAPD tasks. Conclusion: User discomforts were minimized by improving the task environment, unless it had affected the evaluation criteria. Application: We plan to distribute the improved version of the CPAD to the regional rehabilitation hospitals, and the driving support centers for people with disabilities throughout the country, so it could be used as an evaluation tool for disabled drivers' cognitive and perceptual functions.

Asymmetrical Volume Loss in Hippocampal Subfield During the Early Stages of Alzheimer Disease: A Cross Sectional Study

  • Kannappan, Balaji
    • Journal of Integrative Natural Science
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    • v.11 no.3
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    • pp.139-147
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    • 2018
  • Hippocampal atrophy is a well-established imaging biomarker of Alzheimer disease (AD). However, hippocampus is a non-homogenous structure with cytoarchitecturally and functionally distinct sub-regions or subfield, with each region performing distinct functions. Certain regions of the subfield have shown selective vulnerability to AD. Here, we are interested in studying the effects of normal aging and mild cognitive impairment on these sub-regional volumes. With a reliable automated segmentation technique, we segmented these subregions of the hippocampus in 101 cognitively normal (CN), 135 early mild cognitive impairment (EMCI), 67 late mild cognitive impairment (LMCI) and 48 AD subjects. Thereby, dividing the hippocampus into hippocampal tail (tail), subiculum (SUB), cornu ammonis 1 (CA1), hippocampal fissure (fissure), presubiculum (PSUB), parasubiculum (ParaSUB), molecular layer (ML), granule cells/molecular layer/dentate gyrus (GCMLDG), cornu ammonis 3(CA3), cornu ammonis 4(CA4), fimbria and hippocampal-amygdala transition area (HATA). In this cross sectional study of 351 ADNI subjects, no differences in terms of age, gender, and years of education were observed among the groups. Though, the groups had statistically significant differences (p < 0.05 after the multiple comparison correction) in the Mini-Mental State Examination (MMSE) scores. There was asymmetrical volume loss in the early stages of AD with the left hemisphere showing volume loss in regions that were unaffected in the right hemisphere. Bilateral parasubiculum, right cornu ammonis 1, 3 and 4, right fimbria and right HATA regions did not show any volume loss till the late MCI stages. Our findings suggest that the hippocampal subfield regions are selectively vulnerable to AD and also that these vulnerabilities are asymmetrical especially during the early stages of AD.

The Effects of the Activity Program for Preventing Dementia Against Depression, Cognitive Function, and Quality of Life for the Elderly (치매예방을 위한 활동 프로그램이 지역사회 노인의 우울, 인지기능 및 삶의 질에 미치는 효과)

  • Park, Kum-Sook;Jeong, Heon-Young;So, Sun-Yoe;Park, Young-Hee;Yang, Hee-Jung;Jung, Kyoung-Ran;Moon, Soon-Joo;Kim, Hae-Kyoung;Cho, Jung-Hee;Yang, Kyung-Hee
    • Journal of Oriental Neuropsychiatry
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    • v.24 no.4
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    • pp.353-362
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    • 2013
  • Objectives: This study is conducted to identify the effects of the activity program for preventing dementia against depression, cognitive function, and quality of life for the elderly. Methods: A non-equivalent control group with pretest-posttest design was used on 50 elderly who were assigned to the experimental and control group (25 for each group). Results: Cognitive function was significantly different between the two groups of the pretest and posttest (Z=4.217, p<.001). There were significant differences between the two groups of the pretest and posttest (Z=-2.324, p=.020) for the quality of life on the EQ-5D index. Conclusions: These findings confirmed that the activity program for preventing dementia was effective for improving cognitive functions and quality of life for the elderly. Therefore, it is further encouraged to perform the activity programs for preventing dementia within other community health posts and community centers. It is necessary to study the emotional supports from community health posts in the future.

Functions in the Middle School Mathematics: The Cognitive Demand of the Mathematical Tasks (중학교 함수 단원의 수학과제 분석)

  • Hong, Chang-Jun;Kim, Goo-Yeon
    • School Mathematics
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    • v.14 no.2
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    • pp.213-232
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    • 2012
  • The purpose of this study was to examine and analyze the cognitive demand of the mathematical tasks suggested in the middle school textbooks. In particular, it aimed to reveal the overall picture of the level of cognitive demand of the mathematical tasks on function in the textbooks. We adopted the framework for mathematical task analysis suggested by Stein & Smith (1998) and analyzed the mathematical tasks accordingly. The findings from the analysis showed that 95 percent of the mathematical tasks were at low level and the rest at high level in terms of cognitive demand. Most of the mathematical tasks in the textbooks were algorithmic and focused on producing correct answers by using procedures. In particular, the high level tasks were presented at the end of each chapter or unit for wrap up rather than as key resources.

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A Robust Spectrum Sensing Method Based on Localization in Cognitive Radios (인지 무선 시스템에서 위치 추정 기반의 강인한 스펙트럼 검출 방법)

  • Kang, Hyung-Seo;Koo, In-Soo
    • Journal of Internet Computing and Services
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    • v.12 no.1
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    • pp.1-10
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    • 2011
  • The spectrum sensing is one of the fundamental functions to realize the cognitive radios. One of problems in the spectrum sensing is that the performance of spectrum sensing can be degraded due to fading and shadowing. In order to overcome the problem, cooperative spectrum sensing method is proposed, which uses a distributed detection model and can increase sensing performance. However, the performance of cooperative spectrum sensing can be still affected by the interference factors such as obstacle and malicious user. Especially, most of cooperative spectrum sensing methods only considered the stationary primary user. In the ubiquitous environment, however the mobile primary users should be considered. In order to overcome the aforementioned problem, in this paper we propose a robust spectrum detection method based on localization where we estimate the location of the mobile primary user, and then based on the location and transmission range of primary user we detect interference users if there are, and then the local sensing reporting from detected interference users are excluded in the decision fusion process. Through simulation, it is shown that the sensing performance of the proposed scheme is more accurate than that of conventional other schemes

Cognitive and other neuropsychological profiles in children with newly diagnosed benign rolandic epilepsy

  • Kwon, Soonhak;Seo, Hye-Eun;Hwang, Su Kyeong
    • Clinical and Experimental Pediatrics
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    • v.55 no.10
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    • pp.383-387
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    • 2012
  • Purpose: Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. Methods: In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological tests including the Korean versions of the Wechsler intelligence scale for children III, frontal executive neuropsychological test, rey complex figure test, Wisconsin card sorting test, attention deficit diagnostic scale, and child behavior checklist scale. Results: The study subjects included 13 boys and 10 girls aged $9.0{\pm}1.6$ years. Our subjects showed an average monthly seizure frequency of $0.9{\pm}0.7$, and a majority of them had focal seizures (70%). The spike index (frequency/min) was $4.1{\pm}5.3$ (right) and $13.1{\pm}15.9$ (left). Of the 23 subjects, 9 showed frequent spikes (>10/min) on the EEG. The subjects had normal cognitive and frontal executive functions, memory, and other neuropsychological sub-domain scores, even though 8 children (35%) showed some evidence of learning difficulties, attention deficits, and aggressive behavior. Conclusion: Our data have limited predictive value; however, these data demonstrate that although BRE appears to be benign at the onset, children with BRE might develop cognitive, behavioral, and other psychiatric disorders during the active phase of epilepsy, and these problems may even outlast the BRE. Therefore, we recommend scrupulous follow-up for children with BRE.

The Study on Relationship between Social Isolation and Cognitive Function in Elderly Korean (노인의 사회적 고립과 인지기능의 관계에 대한 일 연구)

  • Kim, Young Bum
    • Journal of Digital Convergence
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    • v.16 no.7
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    • pp.429-439
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    • 2018
  • The objective of the study was to analyze difference in cognitive function according to social isolation level in elderly Korean. The author classified the social isolation into the structural isolation and contact isolation. Structural isolation corresponded to the no spouse or no children and the contact isolation corresponded to the absence of contact with children, friends or social association. Author conducted multivariate regression analysis with the elderly people aged 65 years or older from the 5th wave of the Korean Longitudinal Study of Ageing data. Number of sample was 3,971. It was confirmed that the level of cognitive function was lower according to level of social isolation. It was also confirmed that friends/neighborhood isolation, and social activity isolation showed significant relationships with cognitive functions. Based on the results, author suggested that to protect the elderly from negative effects of social isolation, we needed the policy to promote elderly's the participation in social activity. The study to analyze the factors related to social isolation was also needed.

Comparing the Effectiveness of the Frequency and Duration of the Horticultural Therapy Program on Elderly Women with Mild Cognitive Impairment and Mild Dementia

  • Kim, Yong Hyun;Jo, Hyun Soo;Park, Chul-Soo;Kang, Kyungheui;Lee, Euy Sun;Jo, Su Hyeon;Bae, Hwa-Ok;Huh, Moo Ryong
    • Journal of People, Plants, and Environment
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    • v.23 no.1
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    • pp.35-46
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    • 2020
  • The purpose of this study was to investigate the effects of the horticultural therapy program on patients with mild cognitive impairment and mild dementia depending on the frequency and duration of the interventions. We developed the same 15-session program to improve cognitive functions and life satisfaction and alleviate depression of the elderly women with mild cognitive impairment or mild dementia. Subjects in Longer Treatment group participated in the program once a week for 15 weeks and subjects in Shorter Tratmet group participated twice a week for 7½ weeks. This study conducted pretest-posttest verification of both groups using quasi-experimental design involving 21 subjects. Elderly life satisfaction, Geriatric Depression Scale (short form), and the Korean Version of Consortium to Establish a Registry of Alzheimer's Disease (CERAD-K) were used in the evaluation. As a result, both groups showed an increase in life satisfaction, and a decrease in depression. However, there was a significant difference in the changes of the CERAD-K scores between the two groups (p < .05). In Longer Treatment group, life satisfaction increased significantly (p < .001), and depression decreased at a marginally significant level (p = .068), but no statistically significant change was observed in neurocognitive function. In Shorter Treatment group, life satisfaction increased at a marginally significant level (p = .059), and depression and CERAD-K scores decreased significantly (p < .05). However, in the case of Mini-Mental State Examination (MMSE-K), there was no significant change in both groups. According to these results, when planning a horticultural therapy program for persons with mild cognitive impairment or mild dementia, it is effective to organize and execute the program by determining the duration of intervention as 3 to 4 months or longer, even if this reduces the number of interventions per week.

Effects of a Computer-based Cognitive Rehabilitation Therapy on Mild Dementia Patients in a Community (지역사회 경증치매환자를 대상으로 한 전산화 인지재활 치료(COMCOG) 효과)

  • Jeong, Won-Mee;Hwang, Yun-Jung;Youn, Jong Chul
    • 한국노년학
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    • v.30 no.1
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    • pp.127-140
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    • 2010
  • This study aims to understand the effects of a Computer - based Cognitive Rehabilitation Therapy(CBCRT) evidence based on mild dementia patients' ability to activities daily living(ADL), cognitive function and measure of occupational performance and to suggest basic data for a cognitive rehabilitation therapy for dementia patients. Method : A CBCRT was applied two times a week for 5 weeks to 14 mild dementia patients who visited Yongin Center for Managing Dementia in Gyeongi-do between February and August 2009. Based on frame of reference for Visual-Perception a CBCRT was applied at home. Moreover, a one group pretest-post test design was, which is a quasi-experiment and research, also applied in order to verify the effects of the rehabilitation therapy on the subjects' ability to ADL, cognitive function and occupational performance skills. Results: A significant effect was confirmed (p<.05) from the CBCRT which Assessment of Motor and Process Skills(AMPS) processing skills and cognitive function and occupational performance skills. Neither was found any significant effect in improving motor skills from AMPS. Conclusion: It seems that a CBCRT based on evidence and has an effect on the improvement of the ability to ADL and cognitive function of mild dementia patients living in a community. The present author hopes that, in the future, more cognitive rehabilitation programs will be developed to improve the functions of mild dementia patients living in a community.