• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4656-4667
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• 2015

The purpose of this study was to investigate relations among the quality of life, health states, physical functions, cognitive functions, and social supports of the elderly at care facilities. The subjects include the elderly that were living in care facilities in some urban areas and aged 65 or older. The data of total 260 old people were used in analysis. Collected data were analyzed with descriptive statistics, t-test, ANOVA, Pearson correlation, and stepwise multiple regression. The elderly at care facilities, who were considered as physically and cognitive vulnerable, scored higher means on quality of life when they were satisfied with the length of stay and sleeping state, had higher subjective health states, had no tooth inconvenience and forgetfulness, suffered from a lower level of depression, had better cognitive functions, and received higher social supports. Quality of life had correlations with the sleeping state(r=-.20, p<.001), subjective health state(r=-.24, p<.001)s, depression(r=-.30, p<.001), and social supports(r=.30, p<.001). Social supports(${\beta}=.30$, p<.001), depression(${\beta}=-.25$, p<.001), subjective health states(${\beta}=-.22$, p<.001), length of stay(${\beta}=-.22$, p<.001), and sleeping state(${\beta}=-.12$, p=.025) turned out to predict the quality of life of the elderly at care facilities and have close relations with it. In short, the quality of life of the elderly is related to many different factors at care facilities. The findings indicate that nursing interventions and managements for quality of life require a mental and social approach or a whole person approach with a focus on the understanding of individual senior citizens rather than on physical activities and diseases.

• The Mathematical Education
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• v.47 no.3
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• pp.239-259
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• 2008

This paper is to find and to suggest alternative ways of description on function chapters in the middle school mathematics so that the descriptions be more closely related to daily life. The research has two phases: one for belief on the usefulness, the other for cognitive ability to solve the practical problems. Results are as following. 1. Most descriptions of corresponding chapters have emphases on the usefulness of functions so as to enhance beliefs on the use of functions. 2. Most practical functions contain expressions of large constant term and large coefficients in magnitude while those are not in the descriptions of tektbooks, especially in case of using ruled papers. 3. For quadratic functions, most students do not detect the degree of the function from the data presented by pairs of values of x and y. And those are not dealt with in most of textbooks, which are given in the MIC textbook.

• Physical Therapy Korea
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• v.16 no.4
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• pp.44-52
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• 2009

It is known that individual factors as cognitive, perception, emotion, and motivation may greatly influence on recovery from neurologic region. This study was to investigate the effects of environmental reinforcement through motivation to perform the tasks voluntarily on motor and cognition function in rats with focal ischemic brain injury. Focal ischemic brain injury was induced in Sprague-Dawley rats (15 rats, $250{\pm}50$ g) through middle cerebral artery occlusion (MCAo). And then, experiment groups were randomly divided into three groups; The control group: MCAo induction ($n_1$=5), the environmental reinforcement (ER) group: the application for ER after MCAo induction ($n_2$=5), the environmental reinforcement through motivation (ERM) group: the application for ERM after MCAo induction ($n_3$=5). The climbing test (CT) and the modified limb placing tests (MLPTs) to measure the motor function and the Morris water maze acquisition test (MWMAT) and the Morris water maze retention test (MWMRT) to measure the cognitive function were performed. For the CT, the ERM group was significantly larger than the ER group. For the MLPTs, the ERM group was significantly decreased compared to other groups. For the MWMAT, the time to find the circular platform in the ERM group significantly decreased compared to other groups. For the MWMRT, the time to dwell on the quadrant circular platform in the ERM group was significantly increased compared to other groups. These results suggested that the ERM could improve the motor and cognitive functions in the rats with focal ischemic brain injury.

• Journal of Digital Convergence
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• v.16 no.9
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• pp.391-397
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• 2018

The purpose of this study was to explore the effect of recreation therapy program on cognitive function and balance sensation of demented elderly patients. The subjects were 16 elderly patients diagnosed with Alzheimer's dementia, divided into experimental group and control group. Recreation therapy program was provided to experimental group for 6 months and the change of cognitive function and balance before and after treatment was analyzed in both groups. The research concluded that the recreation therapy program maintained or even enhanced cognitive function and balance in the elderly with Alzheimer's dementia. The development along with the verification of effectiveness of non-pharmacological methods such as recreational therapy contributed to the study of treatment for the elderly with dementia.

• Research in Community and Public Health Nursing
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• v.21 no.1
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• pp.101-109
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• 2010

Purpose: This study was to identify the relations among ADL, self-efficacy, physical activity and cognitive function in elders. Methods: A total of 257 subjects aged between 60 and 92 were selected through convenient sampling. Data were collected with a self-reported questionnaire from November 1 to November 30, 2008. Collected data were analyzed with SPSS/WIN 15.0. Results: Differences in ADL, self-efficacy, physical activity, and cognitive functions according to general characteristics were as follows. ADL was significantly different according to age, cohabitation, recognition on health, and successful aging. Self-efficacy was significantly different according to cohabitation, recognition on health, and successful aging. Physical activity was significantly different according to age, educational level, cohabitation, and cognition on health. Cognitive function was significantly different according to age, educational level, job, and recognition on health. The correlation coefficient (r) of the ADL variables was .565 for self-efficacy, .633 for physical activity and .460 for cognitive function. Conclusion: Findings of this study may be useful in understanding the health status of community-dwelling elders and developing more specific health promotion programs.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.19 no.2
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• pp.150-161
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• 2012

Purpose: This study was performed to investigate the influencing factors of cognitive function and depression in elderly. Method: From 3 provinces, 282 elders who resided in community and facilities completed structured questionnaires, including cognitive functions, depression, self-esteem, ADL, and IADL. Data were analyzed by applying ${\chi}^2$-test, ANOVA, partial correlation coefficient, and stepwise multiple regression analysis with SAS 8.12. Results: Community dwelling aged people showed higher scores in MMSE-K, self-esteem, ADL and IADL, and showed lower scores in depression than facility elders. MMSE-K was positively correlated in self-esteem, ADL, and personal cognition of health, except depression. Major factors that affect cognitive function of elderly were residual type, age, and IADL. In addition, major factors that affect depression of elderly were self-esteem, personal cognition of health, and marital status. Conclusions: Based on the results above, it is necessary to identify the status of cognition and depression in the elderly, and to develop nursing intervention programs, which improve cognitive function and reduce depression for aged, especially for the facility admitted aged.

• Journal of Korea Multimedia Society
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• v.20 no.2
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• pp.205-215
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• 2017

The brain magnetic resonance images (MRI) is an important imaging biomarker in Alzheimer's disease (AD) as the cerebral atrophy has been shown to strongly associate with cognitive symptoms. The decrease of volume estimates in different structures of the medial temporal lobe related to memory correlates with the decline of cognitive functions in neurodegenerative diseases. During the past decades several methods have been developed for quantifying the disease related atrophy of hippocampus from MRI. Special effort has been dedicated to separate AD and mild cognitive impairment (MCI) related modifications from normal aging for the purpose of early detection and prediction. We trained a multi-class support vector machine (SVM) with probabilistic outputs on a sample (n = 58) of 20 normal controls (NC), 19 individuals with MCI, and 19 individuals with AD. The model was then applied to the cross-validation of same data set which no labels were known and the predictions. This study presents data on the association between MRI quantitative parameters of hippocampus and its quantitative structural changes examination use on the classification of the diseases.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.4 no.4
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• pp.595-617
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• 2010

This paper proposes a novel of a personalized Computer Assisted Language Learning (CALL) system based on learner's cognitive abilities related to foreign language proficiency. In this CALL system, a strategy of retrieval learning, a method of learning memory cycle, and a method of repeated learning are applied for effective vocabulary memorization. The system is designed to offer personalized learning based on cognitive abilities related to the human language process. For this, the proposed CALL system has a cognitive diagnosis module which can measure five types of cognitive abilities. The results of this diagnosis are used to create dynamic learning scenarios for personalized learning and to evaluate user performance in the learning. This system is also designed in order to have users be able to create learning word lists and to share them simply with various functions based on open APIs. Additionally, through experiments, it has shown that this system helps students to learn English vocabulary effectively and enhances their foreign language skills.

• BMB Reports
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• v.53 no.1
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• pp.20-27
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• 2020

Translocator protein (TSPO), also known as peripheral benzodiazepine receptor, is a transmembrane protein located on the outer mitochondria membrane (OMM) and mainly expressed in glial cells in the brain. Because of the close correlation of its expression level with neuropathology and therapeutic efficacies of several TSPO binding ligands under many neurological conditions, TSPO has been regarded as both biomarker and therapeutic target, and the biological functions of TSPO have been a major research focus. However, recent genetic studies with animal and cellular models revealed unexpected results contrary to the anticipated biological importance of TSPO and cast doubt on the action modes of the TSPO-binding drugs. In this review, we summarize recent controversial findings on the discrepancy between pharmacological and genetic studies of TSPO and suggest some future direction to understand this old and mysterious protein.

• Perspectives in Nursing Science
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• v.9 no.1
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• pp.45-50
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• 2012

Purpose: Despite poor cognitive function in heart failure (HF), few studies have examined cognition and its probable implication in self-care among Korean HF patients. The purposes of this study were (1) to describe cognition in the domains of global, memory, and executive functions, (2) to explore the relationship between cognition and self-care, and (3) to determine the amount of dietary sodium intake among Korean HF patients. Methods: A pilot study was conducted: 7 HF patients (3 men, mean age 68 years) completed face-to-face interviews for neuropsychological tests of cognition and self-care including dietary sodium intake. Results: More than half of the patients had impaired global cognition, memory, or executive function; patients with more severe HF were at higher risk of poor cognitive function. Korean HF patients exhibited poor self-care, with a high dietary sodium intake (5.6 g/day), approximately twice more than the suggested guideline of 2~3 g/day for patients with stable HF. Conclusion: Cognitive dysfunction and inadequate self-care with noncompliance with dietary sodium restriction were evident in Korean HF patients. More studies are warranted that examine the prevalence of cognitive impairment and areas of deficit using neuropsychological tests in a larger sample and that examine how cognition affects self-care and compliance in salt-intake.