• Ocean Systems Engineering
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• v.9 no.2
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• pp.179-190
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• 2019

This paper deals with the problem of the global stabilization for a class of ocean structure systems. It is well known that, in general, the global asymptotic stability of the ocean structure subsystems does not imply the global asymptotic stability of the composite closed-loop system. The classical fuzzy inference methods cannot work to their full potential in such circumstances because given knowledge does not cover the entire problem domain. However, requirements of fuzzy systems may change over time and therefore, the use of a static rule base may affect the effectiveness of fuzzy rule interpolation due to the absence of the most concurrent (dynamic) rules. Designing a dynamic rule base yet needs additional information. In this paper, we demonstrate this proposed methodology is a flexible and general approach, with no theoretical restriction over the employment of any particular interpolation in performing interpolation nor in the computational mechanisms to implement fitness evaluation and rule promotion.

• Molecules and Cells
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• v.43 no.4
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• pp.350-359
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• 2020

Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyl-tRNA synthetase (IleRS), resulting in a block to protein synthesis. Previous studies on Thermus thermophilus IleRS indicated that mupirocin-resistance of eukaryotic IleRS is primarily due to differences in two amino acids, His581 and Leu583, in the active site. However, without a eukaryotic IleRS structure, the structural basis for mupirocin-resistance of eukaryotic IleRS remains elusive. Herein, we determined the crystal structure of Candida albicans IleRS complexed with Ile-AMP at 2.9 A resolution. The largest difference between eukaryotic and prokaryotic IleRS enzymes is closure of the active site pocket by Phe55 in the HIGH loop; Arg410 in the CP core loop; and the second Lys in the KMSKR loop. The Ile-AMP product is lodged in a closed active site, which may restrict its release and thereby enhance catalytic efficiency. The compact active site also prevents the optimal positioning of the 9-hydroxynonanoic acid of mupirocin and plays a critical role in resistance of eukaryotic IleRS to anti-infective agents.

• Journal of Power Electronics
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• v.12 no.4
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• pp.654-663
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• 2012

In this paper, a digital control strategy based on equivalent fundamental and odd harmonic resonators is proposed for single-phase DVRs. By using a delay block, which can be equivalent to a bank of resonators, it rejects the fundamental and odd harmonic disturbances effectively. The structure of the single closed-loop control system consists of a delay block, a proportional gain and a set of zero phase notch filters. The principle of the controller design is discussed in detail to ensure the stability of the system. Both the supply voltage and the load current feedforwards are used to improve the response speed and the ability to eliminate disturbances. The proposed controller is simple in terms of its structure and implementation. It has good performances in harmonic compensation and dynamic response. Experimental results from a 2kW DVR prototype confirm the validity of the design procedure and the effectiveness of the control strategy.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.59-64
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• 2003

The parameter modification of the initial FEM model to match it with the experimental results needs the modal information and the modal sensitivity matrix to the parameter change. There are two cases this methodology is ill-equip to deal with; the deficiency of the necessary modal information and the ill-conditioning of the sensitivity matrix. In this research, a novel concept of the feedback exciter that uses the summation of the white noise and the signals from the measurement sensors multiplied with feedback gains as the reference signal is proposed. There are 2 advantages using this external feedback excitation. First, we can use the change of the system response such as modal data by the active energy Path from the sensor to the exciter. This change of the system response can be additional clues to the system dynamics that we want to know. Secondly, the external energy Path alternates the offset of the Parameter change to the system response. That means the modal sensitivity of the parameters becomes different from the original sensitivities by the feedback excitation. Through the feedback loop, we can change the similar modal sensitivities of some updating parameters and consequently discriminate the parameters using the closed-loop modal data. To demonstrate the discrimination performance, the parameter estimation of an indeterminate structure by use of the feedback method is introduced.

• International Journal of Control, Automation, and Systems
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• v.6 no.3
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• pp.327-338
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• 2008

A fault tolerant control system design technique has been proposed and analyzed for managing performance degradation in the presence of multiple faults in actuators. The method is based on a control structure with a model reference reconfigurable control design in an inner loop and command input adjustment in an outer loop. The reduced dynamic performance requirements in the presence of different actuator faults are accounted for through different performance reduced (degraded) reference models. The degraded steady-state performances are governed by the reduced levels of command input. The reconfigurable controller is designed on-line automatically in an explicit model reference control framework so that the dynamics of the closed-loop system follow that of the performance reduced reference model under each fault condition. The reduced command input level is determined to prevent potential actuator saturation. The proposed method has been evaluated and analyzed using an aircraft example against actuator faults subject to constraints on the magnitude and slew-rate of actuators.

• Journal of Ocean Engineering and Technology
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• v.17 no.5 s.54
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• pp.57-65
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• 2003

This paper proposes an optimum design method of structural and control systems, using a 2-D truss structure as an example. The structure is subjected to initial static loads and disturbances. For the structure, a FEM model is formed. Using modal transformation, the equation of motion is transformed into modal coordinates, in order to decrease D.O.F. of the FEM model. To suppress the effect of the disturbances, the structure is controlled by an output feedback $H_{\infty}$ controller. The design variables of the combined optimal design of the control-structure systems are the cross sectional areas of truss members. The structural objective function is the structural weight. The control objective function is the $H_{\infty}$ norm, the performance index of control. The second structural objective function is the energy of the response related to the initial state, which is derived from the time integration of the quadratic form of the state in the closed-loop system. In a numerical example, simulations have been perform. Through the consideration of structural weight and $H_{\infty}$ norm, an advantage of the combined optimum design of structural and control systems is shown. Moreover, since the performance index of control is almost nearly optimiz, we can acquire better design of structural strength.

• International Journal of Ocean Engineering and Technology Speciallssue:Selected Papers
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• v.6 no.1
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• pp.60-68
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• 2003

This paper proposes an optimum design method of structural and control systems, using a 2-D truss structure as an example. The structure is subjected to initial static loads and disturbances. For the structure, a FEM model is formed. Using modal transformation, the equation of motion is transformed into modal coordinates, in order to decrease D.O.F. of the FEM model. To suppress the effect of the disturbances, the structure is controlled by an output feedback $H_{\infty}$ controller. The design variables of the combined optimal design of the control-structure systems are the cross sectional areas of truss members. The structural objective function is the structural weight. The control objective function is the $H_{\infty}$ norm, the performance index of control. The second structural objective function is the energy of the response related to the initial state, which is derived from the time integration of the quadratic form of the state in the closed-loop system. In a numerical example, simulations have been perform. Through the consideration of structural weight and $H_{\infty}$ norm, an advantage of the combined optimum design of structural and control systems is shown. Moreover, since the performance index of control is almost nearly optimiz, we can acquire better design of structural strength.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10a
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• pp.16-19
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• 1996

In this paper, a sliding mode control scheme that guarantees the smoothness of the control signal and the exponential error convergence is proposed for robot manipulators. The proposed method inserts a low pass filter (LPF) in front of the plant, and the virtual controller is designed for the virtual plant - the combination of the LPF and the robot manipulator. The virtual control signal contains high frequency components because of a switching function. The real control signal, however, always shows a smooth curve since it is an output of the LPF. In addition to the smoothness of the control signal is always assured, the overall system is in the sliding mode at all times, that is, its performance is always invariant under the existence of parameter uncertainties and external disturbances. The closed-loop system is shown to be globally exponentially stable.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1996.04a
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• pp.316-321
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• 1996

The authors has developed the transfer influence coefficient method(TICM) which is an algorithm for the analysis of vibration suitable for a personal computer and applied to many structures such as straight-line beam, plate and shell structures. But TICM can't be applied to the closed loop system and is required extremely much time on the computation of complicate and large structures. Therefore, we now suggest the transfer stiffness coefficient method(TSCM) overcoming these two problems, which consists on the concept of the substructure synthesis method and transfer influence coefficient method. TSCM is formulated for the free vibration analyses of a straight-line distributed beam structure and confirmed by the results of numerical computation to the numerical high accuracy and the high speed.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.10
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• pp.49-55
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• 2000

This study describes the fatigue characteristics for Al2024 alloy, which is aircraft structure material. For this work, the plane-strain fracture toughness test, the plane-stress fracture toughness test and the crack growth rates test were conducted under the standard testing method. Test equipment is a computer-controlled closed-loop fatigue testing machine. The data of each test result is very important to aircraft structure reliability estimation, life prediction, design analysis, endurance analysis and damage tolerance analysis. In addition, the fatigue crack growth threshold($\DeltaKth$) value decreased as the stress ratio increased. Also, $\DeltaKth$ decreased as the thickness increased in LT, TL directions.