• Title/Summary/Keyword: Clinical observation

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Clinical Observation of Urticaria Patients by Oriental medicine (두드러기에 關한 臨床的 考察)

  • Kim, Hae-Jung;Chae, Bhung-Yoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.10 no.1
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    • pp.357-366
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    • 1997
  • Urticaria is an erythematous or white non-pitting edematous plague that changes in size and shape by peripheral extention or regression during the few hours or days. Urticaria is classified as acute or chronic type. The etiology of acute urticaria has been determined in many case, but the cause of chronic urticaria has been determined in only $5\%\;to\;20\%$ of cases. This observation was aimed to evaluate the clinical manifestations and clinical indence of urticaria seen between June, 1995 and November, 1996(18months) at the Department of Dermatology, Oriental Medical Hospital, Kyung Hee University. The results were summarized as follows ; 1. In the cases of 106 patients, $43\%\;were\;male\;and\;51\%$ were female. 2. The pick incidence of age group was 20 to 29($32\%$). 3. The most frequent duration of urticaria was from 2 months to 6 months. 4. In this study, the inciting causes could not be found in $61\%\;of\;acute\;patients,\;60\%$ of chronic patients. 5. Among 107 patients, $5\%$ of all patients had personal history of atopic diseases and $9\%$ of all patients had familly history. 6. Angioedema was founded in 7 patients, and the most common involved site were lips, eyelids and tongue. 7. The most frequently treated prescription was Chhunggisan which occupied $51\%$ of all, Gyakhangjunggisan(41\%$) and Gosamhomasan($25\%$), Bangpoongtongsungsan($22\%$) in that order of frequency.

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Clinical Observation on Hearing Impairment in Diabetes Mellitus Patients (당뇨병 환자의 청각장애에 대한 관찰)

  • 지정민;송재권
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1977.06a
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    • pp.3.3-3
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    • 1977
  • For a year from Jan. 1976 to Dec. 1976, the authors have performed the clinical observation in accordance with audiometric test and clinical findings of 43 cases (male 25: female 18) who were diagnosed of diabetes mellitus in diabetic clinic of our hospital. The results are as follows; 1) Eight of 43 cases reveal hearing impairment, and almostly abrupt drop or descending in hearing types. 2) The incidence of hearing impairment is higher in middle and older age group. 3) Hearing impairment has not related to duration of the disease but blood sugar level and total serum cholesterol level in some extent. 4) The incidence of hearing impairment is higher in cases accompanied by complications such as retinopathy, hypertension, neuropathy etc. 5) In etiology of hearing impairment, multiple factors seem to be concerned.

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The LMOF Preprocessing Tool for Mapping Laboratory Vocabulary to LOINC in Clinical Document Architecture (임상문서표준규격내 검사실 용어의 LOINC 매핑을 위한 LMOF 전처리 도구)

  • Do, Hyoung-Ho;Kim, Il-Kon;Lee, Sung-Kee;Kwak, Yun-Sik
    • Journal of KIISE:Computer Systems and Theory
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    • v.35 no.4
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    • pp.158-165
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    • 2008
  • LOINC (Logical Observation Identifiers Names and Codes) is a database and universal standard for identifying laboratory and clinical test results that is developed and maintained by Regenstrief Institute. Exchanging laboratory test results is one of the most important area in EHR system and the terminology for laboratory test results has to be standardized. In this paper, we present a pre-preprocessing tool that converts a local database in healthcare organizations to LMOF format LMOF format is required by RELMA and our work helps mapping laboratory test results to LOINC very efficiently Our proposed tool provided user friendly interface and 15% keyword reduction in RELMA search compared to no pre-processing RELMA search.

Clinical Analysis of Foreign Bodies in Gastrointestinal Tract in Children (소아에서 위장관내 이물질의 임상적 고찰)

  • Choi, Eunsoo;Lee, Hyo Gyun;Choi, Soo Jin Na;Chung, Sang Young
    • Advances in pediatric surgery
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    • v.20 no.1
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    • pp.12-16
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    • 2014
  • Foreign body ingestion is a common problem among paediatric populations. Most of the ingested foreign bodies spontaneously pass through the gastrointestinal tract, but approximately less then 10% of them remain without being discharged, and trigger complications. Therefore, proper evaluation and treatment according to the situation is required. In this study, clinical progress and complications were analyzed according to the clinical features and treatment in children who ingested foreign bodies. Among pediatric patients under 18 who were admitted to Chonnam National University Hospital after ingesting foreign bodies between January 2008 to June 2012, only the patients who had their foreign body in the gastrointestinal tract were included in this study. Based on medical records, age, type of foreign body, time spent till admission, and whether the endoscopy was done or not, complication were researched retrospectively. According to symptoms and plain abdomen X-ray findings, treatment was chosen and conducted among endoscopy, observation and emergency operation. Among 273 patients, 9 (3.3%) of them had surgical removal. Seven (2.6%) of them had an emergency operation on the day of admission, and the rest 2 (0.7%) had operation during observation. Removal through initial endoscopic approach was tried in 157 (57.5%) patients. Eleven (70.8%) of them had their foreign body removed at the initial trial, and 5 (4.9%) of them at the second trial. Among 109, who were on observation status, 9 (8.3%) of them needed endoscopic removal, and 2 (1.8%) of them suffered from surgical removal. It is thought to be better to approach slowly considering the type, size and symptoms in foreign body ingestion of pediatric patients, rather than immediate and invasive removal.

Histopathological changes on the testis by Ivermectin toxicity (Ivermectin투여가 고환에 미치는 영향에 관한 병리조직학적 관찰)

  • Son, Jeong-hoon;Lee, Cha-soo
    • Korean Journal of Veterinary Research
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    • v.35 no.3
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    • pp.563-573
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    • 1995
  • To know the effect of Ivermectin(IVM) toxicity in testis, histopathologic changes as well as clinical signs were observed in experimental animals including dogs by the subcutaneous injection with 3-50mg/kg of IVM. Clinically, it was observed to have depression and ataxia in all groups whereas tremor and coma in mice, rats and guinea pigs, coma in hamsters and rabbits, and tremor and salivation in dogs were shown. The clinical signs were different by the dosage of IVM, species and individuals in all animals. Susceptibility to IVM was most sensitive in dogs, especially in a Tosa dog and this was susceptible in mice, hamsters and rabbits, guinea pigs and rats in order. Microscopical observation revealed that the seminiferous tubules of testis had decreased thickness of germinal epithelium due to the necrosis and desquamation of the spermatids and spermatocytes. The progressive pattern by the times of administration showed vacuolar formation between the layer of spermatids and spermatogonia due to the marked necrosis of spermatocytes and the presence of multinucleated giant cells derived from spermatid throughout the seminiferous tubules of testis. Only a layer of spermatogonia, a few spermatogonia, and Sertoli cells wore observed with atrophied wavelike basement membrane in the seminiferous tubules of testis. Necrotic germinal cells, sloughed immature spermatids and spermatocytes were present in the lumen of epididymis and ductus deferens. Microscopical observation showed different susceptibility to IVM with clinical observation in which it was also most sensitive in dogs, especially in a Tosa dog and this was susceptible in rabbits and guinea pigs, hamsters, rats and mice in order. It was considered that IVM affects mainly spermatocyte or spermatid stage in the spermatogenesis and disturbs their developing beyond these stage.

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Nonparametric Inference for the Recurrent Event Data with Incomplete Observation Gaps

  • Kim, Jin-Heum;Nam, Chung-Mo;Kim, Yang-Jin
    • The Korean Journal of Applied Statistics
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    • v.25 no.4
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    • pp.621-632
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    • 2012
  • Recurrent event data can be easily found in longitudinal studies such as clinical trials, reliability fields, and the social sciences; however, there are a few observations that disappear temporarily in sight during the follow-up and then suddenly reappear without notice like the Young Traffic Offenders Program(YTOP) data collected by Farmer et al. (2000). In this article we focused on inference for a cumulative mean function of the recurrent event data with these incomplete observation gaps. Defining a corresponding risk set would be easily accomplished if we know the exact intervals where the observation gaps occur. However, when they are incomplete (if their starting times are known but their terminating times are unknown) we need to estimate a distribution function for the terminating times of the observation gaps. To accomplish this, we treated them as interval-censored and then estimated their distribution using the EM algorithm proposed by Turnbull (1976). We proposed a nonparametric estimator for the cumulative mean function and also a nonparametric test to compare the cumulative mean functions of two groups. Through simulation we investigated the finite-sample performance of the proposed estimator and proposed test. Finally, we applied the proposed methods to YTOP data.

Overview for pattern and results of moxibustion-derived clinical trials (뜸을 이용한 RCT임상연구의 경향에 대한 개괄)

  • Son, Chang-Gue
    • Korean Journal of Acupuncture
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    • v.26 no.1
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    • pp.41-49
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    • 2009
  • Objective : To make comprehensive picture of clinical trials using moxibustion and their results by today, then help a strategy for moxibustion-derived clinical studies in the future. Methods : Surveyed literatures containing randomized controled clinical trial (RCT) from PubMed and Korean journals. Analysis was performed according to distribution mainly by study subject, target diseases, study design, and its efficacy. Results : Fifty two literatures were selected according to inclusion criteria of randomized controled clinical study. Moxibustion-derived RCT have been rapidly increased from 2003 since the first was published in China in 1992. The main subjects of RCT are associated with immunity, cancer, arthritis, chronic colitis and urogenital disorders, which are connected to cold-elated pathogenesis. The average number of subjects was 94, and direct-moxibustion was mainly applied. The control groups were set up by giving conventional therapy, herbal medicine, acupuncture or only observation. The most of RCTs showed positive results. Conclusions : This study would be helpful for designing or conducting RCTs to develop the scientific development of moxibustion.

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The Factors Influence of Clinical Competency of Core Basic Nursing Skills During the Clinical Practice in Nursing Students (간호대학생의 임상실습 중 핵심기본간호술 수행자신감에 영향을 미치는 요인)

  • Kim, Dong-Ok;Byun, Soung-Won;Lee, Haejin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.85-92
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    • 2019
  • This study was a descriptive study conducted to identify factors that had an influence on clinical competency of core basic nursing skills(CBNS) during the clinical practice in nursing students. Data were collected from 3rd and 4th grade 190 nursing students in G city using self-report questionnaire, and analyzed using descriptive statistics, the t-test, one way ANOVA, multiple regression with SPSS 23.0 program. This study found that the number of experience CBNS below 5 was 51.1%, and the number of observation CBNS over 11 was 78.4%. Clinical competency according to general characteristics, clinical practice satisfaction and the level of CBNS experience increased with male, increase age and grade, and major subject satisfaction and clinical practice satisfaction, especially, as the number of experience CBNS increased, clinical competency increased(p<0.001). But clinical competency did not differ according to the number of observation CBNS(p=0.463). The factors affecting the clinical competency of nursing students were age, grade, clinical practice satisfaction and the number of experience CBNS. Therefore, it is important to increase the opportunity to directly experience the various CBNS in clinical practice of nursing students in the nursing education curriculum, and it is necessary to find ways to actively use simulation education.

Effects of a Stretching Exercise Combined with Observation Training on Neck Alignment and Balance in Stroke Patients (관찰훈련을 병행한 신장운동이 뇌졸중 환자의 목 정렬과 균형에 미치는 영향)

  • Jeong-Il Kang;Seung-Yun Baek
    • Journal of the Korean Society of Physical Medicine
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    • v.19 no.1
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    • pp.61-68
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    • 2024
  • PURPOSE: This study aimed to provide basic clinical data by analyzing the impact of motion observation training and stretching exercises for improving postures on the neck alignment and balance of stroke patients to enable them to accurately recognize the correct exercise method. METHODS: After sampling 20 stroke patients who met the selection criteria, this study randomly assigned 10 people who were administered the stretching exercise with observation training to the experimental group and 10 who received only the stretching exercise intervention to the control group by drawing lots. Next, neck alignment and balance were pre-tested. All interventions were conducted for 30 minutes, 3 times a week for 4 weeks, and when all the interventions were completed after 4 weeks, neck alignment and balance were re-measured in the same way as the pre-test. RESULTS: The comparison of changes in neck alignment and balance within the experimental and control groups showed statistically significant differences in the craniovertebral angle, cranial rotation angle, and balance (p < .05) (p < .01). Between the groups, statistically significant differences were found in the craniovertebral angle, cranial rotation angle, and balance (p < .05) (p < .01). CONCLUSION: A statistically significant difference in neck alignment and balance was observed in the group that underwent stretching exercises combined with observational training and a statistically significant difference was found between the groups. Therefore, it is believed that observation training should be used in clinical practice to improve forward head posture and restore balance in stroke patients.

A prospective multicenter clinical study on the efficiency of detachable ball- and spring-retained implant prosthesis

  • Min-Jung Kim;Won-Tak Cho;Su-Hyun Hwang;Ji-Hyeon Bae;Eun-Bin Bae;June-Sung Shim;Jong-Eun Kim;Chang-Mo Jeong;Jung-Bo Huh
    • The Journal of Advanced Prosthodontics
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    • v.15 no.4
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    • pp.202-213
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    • 2023
  • PURPOSE. This prospective clinical study was conducted to evaluate the clinical usefulness of the freely detachable zirconia ball- and spring-retained implant prosthesis (BSRP) through a comparative analysis of screw- and cement-retained implant prosthesis (SCRP). MATERIALS AND METHODS. A multi-center, randomized, prospective clinical study evaluating the clinical usefulness of the detachable zirconia ball- and spring-retained implant prostheses was conducted. Sixty-four implant prostheses in 64 patients were examined. Periodic observational studies were conducted at 0, 3, 6, and 12 months after delivery of the implant prosthesis. Factors such as implant success rate, marginal bone resorption, periodontal pocket depth, plaque and bleeding index, and prosthetic complications were evaluated, respectively. RESULTS. During the 1-year observation period, all implants survived without functional problems and clinical mobility, showing a 100% implant success rate. Marginal bone resorption was significantly higher in the SCRP group than in the BSRP group only at the time of implant prosthesis delivery (P = .043). In all observation periods, periodontal pocket depth was slightly higher in the BSRP group than in the SCRP group, but there was no significant difference (P > .05). The modified plaque index (mPI) scores of both groups were moderate. Higher ratio of a score 2 in modified sulcus bleeding index (mBI) was observed in the BSRP group in the 6- and 12-months observation. CONCLUSION. Within the limitations of this study, the newly developed zirconia ball- and spring-retained implant prosthesis could be considered as an applicable and predictable treatment method along with the existing screw- and cement-retained prosthesis.