• Journal of The Association for Neo Medicine
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• v.1 no.1
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• pp.115-122
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• 1996

A clinical observation was done on 98 cases performed neurometer diagnosis before Guibitang administration first, and rechecked neurometer diagnosis after Guibitang administration for 10 days. Electric current post administration was compared with ant administration. The following result were obtained. 1. A peak incidence was observed in 30-39 age group. 37 cases(37.8%) were in 30-39 age group. The ratio of male to female was 1:31.7. 2. Chief complaints were fatigue, menoxenia, indigestion, anorexia, constipation, headache, palpitation, insomnia etc. 3. The common result of neurometer point checking was that patients who had the pecularity of low electric current were much than patients who had the pecularity of high electric current. 4. By neurometer diagnosis a peak incidence was observed in gallbladder. Increment was also highest in gallbladder. Gallbladder has a function of psychomotility in oriental physiology. ?5. After Guibitang administration the increment of neurometer electric current was comparatively high in kidney, stomach, small intestine meridian. According to the above menthioned results I consider that Guibitang has the curative effects along the meridian selectively. and increases in function or preserves health within physycal limit.

• Toxicological Research
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• v.22 no.4
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• pp.439-443
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• 2006

This study was conducted to investigate the potential acute toxicity of Aralia elata by a single oral dose in ICR mice. Thirty mice of each sex were randomly assigned to three groups of 10 mice each. The test articles were administered once by the gavage to mice at dose levels of 0, 2,500 and 5,000 mg/kg body weight. The mortality and changes on body weight and clinical signs of gross observation were monitored for 14 days after dosing. At the end of 14-day observation period, all animals were sacrificed and complete gross postmortem examinations were performed. There were no dead animal and adverse effects on clinical signs, the body weight and the gross finding. As the results, we could not find any toxic effect at the dose levels of 2,500 or 5,000 mg/kg in mice and the minimal lethal dose was considered to be over 5,000 mg/kg body weight in mice.

• Korean Journal of Clinical Laboratory Science
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• v.36 no.2
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• pp.131-136
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• 2004

This study was carried out to investigate effect of lipid metabolism in Viscum album lectin on rats. The lectin was purified by sepharose 4B affinity chromatography and gel filtration using sephadex G-150 with plant material from Viscum album collected in Mt. Duk Yui. After 72 h of $CCl_4$ injection (in olive oil, 1:1, 2 mg/kg) there was a significant increase in serum total cholesterol and triglycerige levels relative to the control group. However, treatment of both Viscum album and purified lectin were significantly decreased lipid parameters against the $CCl_4$-induced. Histological observation basically supported the result obtained from serum lipid assay. The livers of rats challenged with $CCl_4$ produced a marked increase of cytoplasmic vacuoles in number, while the number of necrotic cells and swollen hepatocytes did not change significnatly. Rats administered olive oil alone did not alter the normal hepatic architecture. Histological observation of the liver section in rats treated 72 h with either Viscum album purified lectin or $CCl_4$-induced liver lipogenesis showed decreased numbers of cytoplasmic vaculoes and necrotic cells. The normal hepatic architectural pattern was observed in Hematoxylin-eosin stain. These results suggest that Viscum album lectin has a possible protective effect of lipid metabolim in rats.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.3
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• pp.88-94
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• 2004

Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement of one side face. In the treatment of hemifacial spasm, the Western operation or non-operation therapy has many side effect such as hearing loss, exudative otitis media, facial paralysis etc. So we studied mainly the effect of cause, treatment frequency, diseased part of 29 cases with hemifacial spasm for effective clicical application of oriental medicine. The results of study are as follow; 1. It shows more female patients than male patients, and mostly patients in their forties. 2. The diseased part is shown more on left side than right side, and the left side hemifacial spasm is cured more effective. 3. The causes of hemifacial spasm are mainly stress, ignorance, overwork, and the stress, a cold are more effective causes than ignorance in. 4. The disease period is mainly within six months, and that period is the most effective time. 5. The palpebral site is the most frequent site, ineffective site. 6. The effect go with the treatment frequency is not available. 7. There is a 55 percent improvement of 29 cases.

• Journal of Acupuncture Research
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• v.18 no.5
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• pp.185-194
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• 2001

Objective : By process of treatment for a case which diagnosed as Atlanto-Axial Fracture-Dislocation and admitted from the 2nd, December, 2000 to the 18th, December, 2000, the results are as follows. Methods : Clinical observation and analysis about a case of Atlanto-Axial Fracture-Dislocation was done, who visited Dong-in-dang Oriental Medicine Hospital. This case is managed by integrated therapy of oriental medicine. This patient was diagnosed as stagnation of Ki and stasis of blood(氣滯血瘀), deficiency of Um of the liver and kidneys(肝腎陰虛) and medicated gamisekyung-tang(加味舒經湯) and kanghwalsokdan-tang(羌話續斷湯). As acupucture treatments, we could get the effective results by providing the patient with acupuncture on the nape, shoulder, Lt upper limb and Rt distant point Conclusion : We could get the effective results that case of Atlanto-Axial Fracture-Dislocation with severe rigid neck and Motor disturb of neck, was treated with oriental medicine and acupuncture therapy.

• Journal of Pharmacopuncture
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• v.12 no.2
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• pp.85-90
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• 2009

Objectives : Sweet bee venom(SBV) is pure melittin, the main component of bee venom, made by removing another components through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. In the using SBV, 2 patients were experienced anaphylaxis by SBV. So, we reported the process of anaphylaxis and consider these situation. Methods : We observed 2 patients suffered from anaphylaxis after treated with SBV in the Korean Medical Hospital, Sangji University. Results : Though SBV was removed allergen from bee venom, it is not possible to complete prevention of anaphylactic shock in the clinics. So, Korean medical doctor using BV or SBV must be prepare the system consider a countermeasure by anaphylaxis.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.16 no.1
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• pp.1-8
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• 2012

Objectives Although the faith that pulse diagnosis via a thread, namely "Xuanxizhenmai", had been applied to some women in royal families, is widely spread in East Asian countries, but it is still controversial that whether this faith is based on historical facts or just originated from some folk tales. So we provided some reasonable clues to interpret that faith. Methods The digitalized Annals of Joseon Dynasty and Twenty Five Books of Chinese History were used for historical example search. Conventional internet search engines are widely used for investigation of other examples and related interpretations. Additionally, a pilot observation with nylon threads and optical vibration detection devices was performed to confirm it's feasibility. Results Although there are a few evidences supporting Xuanxizhenmai's existence in Qing dynasty, no evidence was found to show it's existence in authoritative annals of Korea and China. The pilot observation showed that in optimal environment, some intense arterial pulse could be propagated dozens of centimeter, but it was not applicable to clinical needs. Conclusions Pulse propagation via a thread was proved to be reproducible within limited extents, but pulse diagnosis via a thread, namely Xuanxizhenmai, seem to have never been used for proper clinical purpose.

• The Journal of Korean Medicine
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• v.21 no.3
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• pp.129-139
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• 2000

Clinical observation was made on 210 cases of CVA that were confirmed through brain CT, MRI scan and clinical observation. They were hospitalized in the oriental medical hospital of Kyungwon University from January to December in 1998. Objective : To evaluate the current status of cerebrovascular disease in Korea, we performed observation on stroke patients. Methods : We performed a retrospective study on 210 cases of stroke who had been admitted to the Dept. of Internal Medicine, College of Oriental Medicine, Kyungwon University from Jan. 1, 1998 to Dec. 31, 1998. Results : The incidence was highest in the patients with the age of above fifty. The frequency of strokes was similar between male and female cases. Ischemic stroke(70.0%) was more common than hemorrhagic stroke(20.5%), with transient ischemic attacks(9.5%) occuring less frequently. Middle cerebra! arterial territory was the most commonly involved site in ischemic strokes. Among intracerebral hemorrhages, putaminal hemorrhages were found in 69.8%, and was followed by IVH(9.3%), IVH with ICH(7.0%), subcortical hemorrhages (4.7%) and pontine hemorrhages(4.7%). The most ordinary preceding disease was hypertension. The next was diabetes mellitus. Most cases were given simultaneous treatment in both western and oriental medical methods. Conclusions : Generally it is thought that CVA occurs frequently in winter. But our observations reveal no such relationship. The predisposing factors of cerebral infarction were usually initiated during the time of resting and sleeping and those of cerebral hemorrhage chiefly during the time of exercising. I Patients whose condition of consciousness was bad at the time of admission tended to have a bad prognosis. This study suggests changing trends of stroke in Korea, and that a multicenter prospective study using stroke registry is required for confirmation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.8
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• pp.3479-3483
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• 2015

Objective: Patients with hepatocellular carcinoma (HCC) in stage Barcelona Clinic Liver Cancer (BCLC)-A were grouped based on whether they were accompanied with hepatitis B virus (HBV) infection or not so as to explore the clinical characteristics and prognostic conditions of HCC patients with non-HBV/hepatitis C virus (HCV). Materials and Methods: Clinical data of 64 stage BCLC-A HCC patients with non-HBV/HCV infection (observation group) who received radical hepatectomy in the Affiliated Cancer Hospital of Guangxi Medical University from January, 2006 to November, 2014 were retrospectively analyzed and compared with those of 409 stage BCLC-A HCC patients with HBV infection (control group) in corresponding period. Results: The postoperative 1-, 3- and 5-year recurrent rates of the observation group were 25%, 38.6% and 48.8%, with postoperative mean and median disease-free survival time being 49.1 months and 62.0 months, respectively. Additionally, the postoperative 1-, 3- and 5-year survival rates of observation group were 90.1%, 72.7% and 62.0%, with the mean and median survival times being 54.4 months and 70.0 months, respectively. Conclusions: The 1-year recurrent rate is the highest in HCC patients with non-HBV/HCV, and almost half of the patients have recurrence within 1 year, after which the recurrent rate decreases along with the time.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.3
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• pp.272-278
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• 2017

Purpose: The aim of the present prospective clinical study was to assess the cumulative survival rate (CSR) of Neobiotech implants restored with fixed partial prosthesis in relation to its potential risk factors. Materials and methods: Thirty six partially edentulous patients received Neobiotech implants and implant supported fixed partial prosthesis at Korea University Guro Hospital Dental Center from November 2009 until November 2011. The observation period was set from the implant placement and the last clinical visit until December 2015. Implant survival rate was determined using the Kaplan-Meier method. The relationship between implant survival rate and the potential risk factors were analysed using the multi Cox proportional analysis (P<.05). Results: A total of 69 implants were placed in 36 patients after a mean observation period of 45.9 months. Two out of 69 implants failed before loading, yielding a 5-year cumulative survival rate of 97.1%. The maxillary implants have a lesser CSR than the mandibular implants based on log rank test analysis (maxilla=91.3%; mandible=100% P<.05). However, the multi Cox proportional analysis showed that implant location has no significant correlation with implant failure (P>.05). Conclusion: Neobiotech implants showed predictable results with a 5 year cumulative survival rate of 97.1%.