• Title/Summary/Keyword: Clinical neurology

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Cases of Adverse Drug Reaction Monitoring

  • Park, Kyoung-Ho;Son, In-Ja;Park, Byung-Joo
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.432-432
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    • 2002
  • Drug used in hospital is allowed marketing through after pharmacological and toxicological tests using various animals and clinical test of human in developing state. But as pre-marketing clinical study take short period with relatively a few of patients and strict selection criteria of people, pediatric, geriatric. pregnancy, liver and kidney patients may be excluded. As the safety of drug isn't completely evaluated before launching. it is important to collect and evaluate drug adverse reaction newly reported by medical practitioners and pharmacists. (omitted)

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Consideration of Ruptured Cerebral Aneurysms Clipping Surgery

  • Park, Sang-Ku;Kim, Dong-Jun;Han, Hung-Tae
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.1
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    • pp.24-27
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    • 2015
  • To measure motor evoked potentials (MEP) during emergency surgery is often difficult in patients with subarachnoid hemorrhage (SAH) from a ruptured cerebral aneurysm, The cause of these difficulties may be considered as damage to the motor pathway by hemorrhage. To identify the cause of difficulties in measuring MEP, we defined the association between motor evoked potentials during surgery and the severity of the hemorrhage in patients with subarachnoid hemorrhage.

Muscle-specific receptor tyrosine kinase (MuSK) myasthenia gravis associated with castleman disease

  • Oh, Jeeyoung;Yang, Woo Ick;Cho, Jeong Hoon;Sunwoo, Il Nam
    • Annals of Clinical Neurophysiology
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    • v.19 no.1
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    • pp.74-76
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    • 2017
  • Muscle specific tyrosine kinase (MuSK) myasthenia gravis (MG) is a rare subtype of MG, which is immunologically distinct and differential therapeutic response. Though MG is often associated with other autoimmune disorders or malignancy, concurrence of other disease and MuSK MG has been infrequently reported. We present a patient of MuSK MG associated with multicentric Castelman disease.

Delayed diagnosis of intramedullary spinal cord germinoma

  • Kim, Haelim;Lee, Eung-Joon;Sung, Jung-Joon
    • Annals of Clinical Neurophysiology
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    • v.22 no.2
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    • pp.109-111
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    • 2020
  • Germ-cell tumors (GCTs) are common in the central nervous system. GCTs are highly sensitive to radiotherapy and chemotherapy and can be cured without radical surgery. However, this tumor produces nonspecific imaging findings, and its rarity can make diagnosis challenging. Here we report a case in which the first diagnosis was uncertain and follow-up imaging revealed intramedullary germinoma. The patient underwent chemotherapy and radiotherapy after the diagnosis.

Application of respiratory function tests in patients with neurological diseases

  • Ilhan Yoo;Seok-Jin Choi;Jung-Joon Sung
    • Annals of Clinical Neurophysiology
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    • v.25 no.1
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    • pp.1-9
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    • 2023
  • Breathing is controlled by complex interactions between the central and peripheral nervous systems in conjunction with the respiratory system. Neurological diseases predispose patients to nocturnal desaturation and pneumonia due to respiratory dysfunction, which increases mortality, daytime sleepiness and fatigue, and reduces the quality of life. Respiratory function tests are required to identify respiratory function decline and to consider compensatory management. This review summarizes the characteristics of several respiratory function tests and their applications to neurological diseases.