• Journal of Digital Convergence
• /
• v.18 no.12
• /
• pp.401-412
• /
• 2020

This study was to determine differences and relations in nursing students' clinical practice stress and clinical competence by gender role identity. The study made a questionnaire survey of 450 nursing students of 2 colleges in J city, Gyeongnam, from June 1st to 30th, 2020. Data from 417 sheets were finally analyzed with descriptive statistics, χ2test, t-test, ANOVA, Scheffe test, correlation and hierarchial regression analysis. The analysis found that most of the participants belonged to undifferentiated type(34.3%) in gender role identity. Clinical competence showed significantly different(F=20.98, p<.001), but clinical practice stress showed no significant difference depending on that identity(F=1.56, p=.199). Clinical competence had positive correlations with the index of masculinity(r=.397, p<.001) or the index of feminity(r=.325, p<.001), but had no with clinical practice stress(r=.061, p=.217). Gender role identity turned out to be a factor that would significantly influence clinical competence(F=6.67, p<.001). These findings suggest that gender role identity of nursing students should be confirmed prior to clinical practice education and, thereon, interventions for clinical competence improvement should be developed.

• Korean Journal of Adult Nursing
• /
• v.19 no.4
• /
• pp.593-602
• /
• 2007

Purpose: The purpose of this study was to develop an e-learning orientation program for nursing students(junior), to evaluate the program, and to find out its effects on adapting to clinical practicum. Methods: The e-learning orientation program was developed according to ADDIE model(analysis, design, develop, implement, evaluate) using an Active Tutor Program. Twelve nursing professionals and 31 nursing students(learners) evaluated the e-learning orientation program. Thirty one nursing students participated in the e-learning orientation program both on-line and off-line. Results: The e-learning orientation program consisted of 5 parts including 'Taking a lesson in gastrointestinal tract', 'Fundamental nursing skill and reading a medical chart', 'Taking a ward orientation by head nurse', 'Clinical practice with preceptors', and 'Writing for case report'. Adapting scores to clinical practicum were significantly different between pre-test and post-test(t=-5.76, p=.000). Conclusion: The e-learning orientation program of on-line and off-line has an effect on adapting to clinical practicum for nursing students.

• The Korean Journal of Health Service Management
• /
• v.7 no.4
• /
• pp.105-117
• /
• 2013

The purpose of this study was to identify the relationships among critical thinking disposition, professional self-concept and clinical competence in nursing students. The participants were 291 nursing students in Gwangju Province. A questionnaire survey was conducted from March 02 to 16, 2013. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe test, pearson's correlation coefficients, and stepwise multiple regression analysis with SPSS/WIN 20.0 version. There was a significant positive correlations among critical thinking disposition, professional self-concept, and clinical competence. The variable predicting clinical competency were professional self-concept and critical thinking disposition. These factors accounted for 44.1% of the variance. The findings of this study suggest that the most influential factor for clinical competence was professional self-concept. Therefore it is necessary to improve professional self-concept through effective education program.

• Herbal Formula Science
• /
• v.24 no.4
• /
• pp.289-300
• /
• 2016

Objectives : Taglisodog-eum(TSE), a poly herbal formula, has been widely used to improve carbuncles by removing inflammation of the lymphatic channels in Traditional Korean Medicine. We previousely reported the action mechanism of TSE on experimental atopic dermatitis and the establishment of formulation for TSE ointment. In this study, we examined the toxicity test on skin and eye irritation by TSE ointment to prove the safety of Taglisodog-eum ointment in clinical use. Methods : Acute skin toxicity of the TSE ointment was evaluated in Sprague-Dawley(SD) rats. After dermal administration of TSE ointment(2,000mg/kg), body weight, mortality, and clinical signs of the rats were observed for 14days. Primary skin irritation and ocular irritation tests for TSE ointment were performed in male New Zealand White Rabbits. In dermal and ocular irritation test, body weight, mortality, clinical signs, Primary Irritation Index(P.I.I.), and The Index of Acute Ocular Irritaion(I.A.O.I.) of rabbit were observed after applying at abraded skin and eye balls with Taglisodog-eum ointment. Results : In the results of acute skin toxicity, no significant differences were found in body weight, the clinical sign and the mortality between control and TSE ointment treated group. In primary dermal irritation test, body weight, the clinical sign and the mortality were not significantly changed and Primary Irritation Index(P.I.I.) was 0.8, indicating TSE ointment as weak irritant material. In ocular irritation test, The Index of Acute Ocular Irritaion was 0.0, indicating TSE ointment as non-irritating to the eye of the rabbits. To evaluate toxicity of the TSE ointment in animal test, body weight, the clinical signs, the skin and eye irritation check were conducted; TSE ointment was considered to be weak dermal irritant in test animals. The no response of eye irritation test was observed in this experimental condition. Conclusions : According to the above toxicity test, We consider that this results is helpful for saying about the safety of TSE ointment in clinical use.

• Journal of Digital Convergence
• /
• v.18 no.7
• /
• pp.279-287
• /
• 2020

For effective clinical practice education, this study was conducted to find out the effects of learning practical subjects on the core competency and satisfaction level of clinical practice on nursing students. The research subjects were divided into groups that conducted four core nursing education classes eight hours a day for two weeks, and groups that received traditional lecture-oriented education, and a questionnaire was prepared and reported by themselves after 15 weeks of clinical practice. The collected data was analyzed using frequency, percentage, mean and standard deviation, chi-square test, and t-test using the SPSS 21.0 program. The findings supported the hypotheses in critical thinking propensity and clinical practice satisfaction, and the hypotheses in leadership, problem-solving and communication skills were rejected. The results of this study confirmed that practical training for strengthening core practical skills has a positive effect on the critical thinking tendency and clinical practice satisfaction of nursing students. Therefore, it can be used as an effective practical training arbitration in nursing education.

• Journal of the Korean Applied Science and Technology
• /
• v.38 no.4
• /
• pp.1020-1028
• /
• 2021

The purpose of this study was to investigate the factors affecting clinical competence on early stage nurse working in a general hospital. Data were collected by questionnaires on early stage nurses from september 11 to september 30, 2020. Data were analyzed by t-test, ANOVA, Scheffe test, Pearson correlation coefficients and multiple regression analysis, using SPSS WIN program. The degree of dysmenorrhea was 2.77 points, clinical competence was 3.44 points. Dysmenorrhea was negative correlated with clinical competence(r=-.226, p=.002). Response of autonomic nervous system was identified as factors influencing clinical competence(𝛽=-.261, p= .001). The model explained 22.1% of the variables. These results suggest that we need intervention education program for response of autonomic nervous system in order to improve the clinical competence of early stage nurses.

• Biomedical Science Letters
• /
• v.11 no.3
• /
• pp.389-396
• /
• 2005

Resent studies have reported increased isolation of extended-spectrum $\beta-lactamase$ (ESBL) producing strains at several hospital in Korea. We studied to investigate the isolation rates of ESBL strains from clinical isolates of Klebsiella pneumoniae and to characterize differences in types using analyses of genotyping and antibiotic susceptibility test. Antibiotic susceptibility test with confirmation of ESBL by double disk synergy test was performed on the 54 ESBL strains of Klebsiella pneumoniae from a hospital in Busan. Transfer of resistant gene in ESBL strains resistant to 3rd generated antibiotics was confirmed by transconjugation test using E. coli $RG176^{nal(r)}$. blaTEM, blaSHV, blaCTX-M genes were detected by PCR. ESBL producing strains had 100% of resistant rate to ampicillin, azteronam, cefazolin, cefepime and ceftriaxone ($\beta-lactam$ antibiotics). Forty strains of bla TEM$(74\%)$, 41 strains of bla SHV $(76\%)$, 23 strains of bla CTX-M $(43\%)$ were found, respectively. The strains had one or more genes. They had high resistant rates to $\beta-lactam$ antibiotics including cephalosporin. The resistant rates of strains with multiple resistant genes were higher than those of strains with single resistant gene.

• Korean Journal of Clinical Pharmacy
• /
• v.22 no.1
• /
• pp.9-12
• /
• 2012

Background: Cefcapene pivoxil hydrochloride, is an ester-type oral cephem antibiotic. This study was performed to compare the pharmacokinetics and evaluate the bioequivalence of two cefcapene pivoxil hydrochloride 75 mg formulations. Method: In a randomized $2{\times}2$ crossover study, sixty healthy male volunteers were randomly assigned into two groups. After a single dose of 75 mg cefcapene pivoxil hydrochloride oral administration, blood samples were collected at specific time intervals from 0-12 hours. The plasma concentrations of cefcapene pivoxil hydrochloride were determined by LC-MS/MS. The pharmacokinetic parameters were determined from the plasma concentration-time profiles of both formulations. The pharmacokinetic parameters such as $AUC_{last}$, $AUC_{inf}$ and $C_{max}$, were calculated and the 90% confidence intervals for test/reference ratio for pharmacokinetic parameters were obtained by analysis of variance on logarithmically transformed data. Results: The mean value for $AUC_{last}$ in test and reference drug was $4053.1{\pm}876.5\;ng{\cdot}hr/mL$ and $3595.7{\pm}1029.1\;ng{\cdot}h/mL$, respectively. The mean value for $C_{max}$ in test and reference drug was $1324.9{\pm}321.4$ ng/mL and $1159.1{\pm}335.9$ ng/mL, respectively. The 90% confidence intervals of the $AUC_{last}$ and $C_{max}$ ratio for test drug and reference drug were log 1.09-log1.22 and log 1.09-log1.24, respectively. No adverse events were reported by subjects or found on analysis of vital signs or laboratory tests. Conclusion: This single dose study found that the test and reference products met the regulatory criteria for bioequivalence in these health volunteers. Both formulations were safe and well tolerated in 75 mg of cefcapene pivoxil hydrochloride.

• Proceedings of the Korean Statistical Society Conference
• /
• 2002.11a
• /
• pp.79-83
• /
• 2002

A phase III clinical trial of a new drug for neutropenia induced by chemotherapy is presented and consider adding random effects in crossover design which was used in the clinical study. The diagnostics for its heteroscedasticity based on score statistic is derived for detecting homoscedasticity of errors in crossover design. A small simulation study is peformed to investigate the finite sample behaviour of the test statistic which is known to have an asymptotic chi-square distribution under the null hypothesis.

• Journal of Biomedical Engineering Research
• /
• v.16 no.2
• /
• pp.139-148
• /
• 1995

In this paper we report the device of a multi-channel clinical instrument developed for determi¬nation of the levels of the urinary urobilinogen, glucose, ketone, bilirubin, protein, ascorbic acid, nitrite, pH, occult-blood, specific gravity, and leukocytes semiquantitatively. The test parameters are expressed on the dry test strips as a range of color intensities by chemical reactions. The instrument measures the value of each substance by reading the reflectance light emanated from the test strips. We also designed the reagent strip cassette and loader in order to intercept the outside interference. The loader can be operated semi-automatically. The light source is consisted on light emitting diodes at three specific wavelengths (560 nm, 610 nm, 650 nm). Precision of the system was evaluated by testing a series of commercial control urine samples. Furthermore, the performance of the instrument was compared with two other test methods on the urine samples from 100 persons. Our results showed a good repeatability between tests and a satisfactory agreement between the readings by our instrument and visual evaluation.