• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4393-4399
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• 2015

Background: To explore the independent prognostic factors for the recurrence/metastasis of patients with locoregionally advanced nasopharyngeal carcinoma (LANPC). Materials and Methods: A total of 604 patients initially diagnosed as LANPC by pathohistology in Fujian Provincial Cancer Hospital were selected to analyze the relationship between the clinical pathological patterns, therapeutic protocols and clinical stages with the recurrence/metastasis of LANPC. Results: The 1-, 3- and 5-year locoregionally recurrent rates of LANPC patients were 2.0%, 9.5% and 12.9% respectively, with average recurrent period being 78 months. Univariate analysis results indicated that clinical stages had certain influence on the recurrent period of LANPC patients. However, COX regression models showed that ages, genders and clinical stages were not the independent prognostic factors influencing the recurrence. The 1-, 3- and 5-year metastatic rates of LANPC patients were 6.6%, 17.5% and 18.8% respectively, with average metastatic period of 73 months. Univariate analysis results demonstrated that ages, N stages, clinical stages, locations of lymph node, retropharyngeal lymph node and extracapsular invasion of lymph node had certain influence on the metastatic period of LANPC patients. Additionally, further COX regression analysis results suggested that T stages, reduction protocols and extracapsular invasion of lymph node were the independent prognostic factors influencing the metastasis of patients with LANPC, in which T stages and extracapsular invasion of lymph node were the pestilent factors while reduction protocols the protective factor. Conclusions: Induction chemotherapy is beneficial to LANPC patients with initial treatment, and the metastatic rate decreases greatly after the application of reduction chemotherapy.

• Restorative Dentistry and Endodontics
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• 제10권1호
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• pp.115-126
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• 1984

The purpose of this study was to determine the incidence and the degree of interappointment pain and post obturation pain associated with the pretreated clinical factors or conditions, and to examine the correlation between the success or failure and the pretreated clinical factors or conditions and postoperative pain. The author experienced the conventional root canal therapy in one hundred fifty-one teeth after recording the following clinical factors or conditions - sex, age, pulp vitality status, presence or absence of periapical rarefaction, single or multirooted teeth, pretreatment pain, and investigated the pain during and after treatment for seven days. After six months all the cases were re-evaluated through the clinical sign, symptom, and the recalled radiograph. The following results were obtained; 1. Of the 151 teeth (73.5%) had no interappointment pain, 31 teeth (20.5%) slight pain; and 9 teeth (6.0%) moderate to severe pain. 2. The presence of the pretreatment pain significantly increased the incidence and degree of interappointment, and there were no significant relationship between interappointment pain and other clinical factors or conditions. 3. Of the 151 teeth, 142 teeth (4.0%) experienced no post obturation pain, 3 teeth (2.0%) slight pain, 6 teeth (4.0%) moderate to severe pain. 4. There were no statistical correlation between postobturation pain and any of the clinical factor or conditions. 5. 141 teeth (3.4%) of 151 teeth were evaluated as success in this study, and success rate was decreased significantly in the cases of periapical rarefaction before treatment and postobturation pain. But there were no significant relationship between success or failure and other clinical factors or conditions.

• 근관절건강학회지
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• 제28권3호
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• pp.263-274
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• 2021

Purpose: This descriptive research study investigated the effects of temperament and character, emotional intelligence on self-leadership of clinical nurses. Methods: This study recruited clinical nurses at a tertiary general hospital located in S city through convenience sampling. A survey was conducted from April 10 to May 5, 2020, using offline questionnaires. A total of 343 answers were analyzed using descriptive statistics and a three-step hierarchical regression analysis with the SPSS 22.0 program. Results: Factors influencing self-leadership of clinical nurses at a tertiary general hospital in S city were persistent among temperament (β=.331, p<.001), personal maturity (β=.408, p<.001), and total emotional intelligence (β=1.062, p<.001). These factors contributed 58% of self-leadership (F=29.20, p<.001). Conclusion: It was confirmed that persistent among temperament and personal maturity among character, emotional intelligence were factors affecting self-leadership of clinical nurses. Therefore, it is necessary to develop and provide programs to control the factors affecting self-leadership of clinical nurses to increase self-leadership.

• 대한의생명과학회지
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• 제27권4호
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• pp.195-207
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• 2021

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen capable of causing human diseases, such as soft tissue infection, bacteremia, endocarditis, toxic shock syndrome, pneumonia, and sepsis. Although the incidence rate of diseases caused by MRSA has declined in recent years, these diseases still pose a clinical threat due to their consistently high morbidity and mortality rates. However, the role of virulence factors in staphylococcal infections remains incompletely understood. Methicillin resistance, which confers resistance to all β-lactam antibiotics in cellular islets, is mediated by the mecA gene in the staphylococcal cassette chromosome mec (SCCmec). Differences in SCCmec types and differences in their sizes and structures serve epidemiological purposes and are used to differentiate between hospital-associated (HA)-MRSA and community-associated (CA)-MRSA. Some virulence factors of S. aureus are also providing a distinction between HA-MRSA and CA-MRSA. These factors vary depending on the presence of toxins, adhesion, immune evasion, and other virulence determinants. In this review, we summarized an overview of MRSA such as resistance mechanisms, SCCmec types, HA- and CA-MRSA, and virulence factors that enhance pathogenicity or MRSA epidemiology, transmission, and genetic diversity.

• 한국콘텐츠학회논문지
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• 제16권2호
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• pp.456-466
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• 2016

본 연구는 간호 대학생의 임상실습 관련 피로에 영향을 미치는 요인을 파악하기 위한 서술적 조사연구이다. 임상실습이 끝난 직후 3학년과 4학년 간호 대학생 중 연구 참여에 동의한 총 129명을 대상으로 하였으며, 구조화된 설문지를 이용하여 자기기입식 질문지법으로 자료 수집하였다. 수집된 자료는 SPSS 20.0 프로그램을 이용하여 분석하였다. 임상실습 스트레스, 불안, 분노, 자기효능감, 수면의 질이 피로와 유의한 상관관계가 있었다. 간호 대학생의 임상실습 관련 피로에 영향을 미치는 요인은 수면의 질, 불안, 운동빈도, 임상실습 스트레스 이었으며, 이들 변인은 임상실습 관련 피로 총 변량의 33.6%를 설명하였다. 수면의 질이 임상실습에 가장 중요한 요인이었고, 임상실습 스트레스와 불안이 수면의 질과 관련된 유의한 변수로 나타나 간호 대학생의 임상실습 피로와 관련된 중재를 계획할 때 임상실습 스트레스와 불안을 감소할 수 있는 프로그램 및 규칙적인 운동으로 자신을 관리할 수 있도록 하며, 수면의 질 또한 우선적으로 고려되어져야 한다.

• 한국엔터테인먼트산업학회논문지
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• 제14권1호
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• pp.137-147
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• 2020

본 연구는 작업치료대학생의 임상수행능력을 측정하는 척도를 개발하고 타당화 하는 데 목적이 있다. 임상수행능력 척도 개발은 임상수행능력의 개념과 선행연구를 분석하였으며 초점집단면담(FGI)을 거쳐 구성요인과 예비문항을 제작하였다. 다음으로 이 문항들에 대해 4인의 전문가를 대상으로 내용타당도 검증을 실시하여 36개의 예비문항을 개발하였다. 최종 척도 문항을 선정하기 위해 203명의 작업치료학과 3, 4학년을 대상으로 본 검사를 실시하여 문항분석과 구인타당도를 검증하였다. 문항분석 결과 삭제된 문항은 없었고, 탐색적 요인분석을 실시한 결과 전문의식 요인 8문항, 작업치료 평가요인 11문항, 작업치료 중재요인 4문항, 의사소통 요인 4문항으로 총 4요인 27개 문항으로 추출되었다. 내적일관성 계수인 Cronbach's α를 통해 요인별 신뢰도를 검증한 결과, .87~.94로 나타났으며, 전체 신뢰도는 .96으로 나타나 양호한 것으로 분석되었다. 임상수행능력 척도 총점과 요인들 간 상관은 모두 통계적으로 유의미하게 나타났다. 확인적 요인분석을 실시한 결과 4개 요인 27문항에 대한 요인구조의 적합도 지수는 (χ²=.76, df=.31, CFI=.81, TLI=.80, RMSEA=.79) 수용 가능한 수준으로 볼 수 있다. 임상수행능력 척도는 작업치료대학생을 대상으로 임상실습 전·후의 임상수행능력을 객관적으로 진단하거나 평가하는 데 유용하게 활용될 것을 제언한다.

• 근관절건강학회지
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• 제27권2호
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• pp.142-152
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• 2020

Purpose: This study involeved a descriptive survey to identify clinical practice satisfaction, self-esteem, and nursing professionalism of nursing college students and determined the factors that affected their nursing professionalism. Methods: Data were collected through a survey of conducted from December 4 to December 20, 2019 (N=186). The relationship among variables was analyzed using Pearson's coefficient correlation and affecting factors for turnover intention were identified by using multiple linear regression. Results: The research results demonstrate that the mean of nursing students' clinical practice satisfaction mean was 3.64 (5 total), the mean of self-esteem was 3.84 (4 total), and the mean of nursing professionalism mean was 3.89 (5 total). Nursing professionalism was significantly different by age and satisfaction with major. Nursing professionalism had positive relationships with clinical practice satisfaction, self-esteem, and satisfaction with major, but had a negative relationships with age. Clinical practice satisfaction, self-esteem, satisfaction with major, and age were identified as influencing factors in turnover intention, and the explanatory power was 43.3%. Conclusion: A strategy to increase clinical practice satisfaction and to enhance self-esteem in nursing college students is necessary. Likewise, further analysis and programs to improve clinical practice environments and training systems should be implemeted.

• 보건의료산업학회지
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• 제14권2호
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• pp.117-129
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• 2020

Objectives: A descriptive survey was used in this study to identify the relationship between nursing students' grit, critical thinking disposition, and clinical competence and to examine factors that influence clinical competence. Methods: Data were collected from 241 nursing students and analyzed using t-test, ANOVA, Scheffé test, Pearson correlation, and stepwise multiple regression analysis with the SPSS/WIN 24.0 PC program. Results: Clinical competence was found to have significant pure correlations with critical thinking disposition (r=.49, p<.001), and grit (r=.31, p<.001). The most influential factors influencing nursing students' clinical competence were critical thinking disposition (β=.35, p<.001), and grit (β=.28, p<.001), and these factors explained 33% of the variance in clinical competence. Conclusions: The findings indicate the need to develop and apply strategies and educational programs to enhance individual nurse's critical thinking disposition and grit. Furthermore, exploration is needed on ways to enhance clinical competence.

• 한국직업건강간호학회지
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• 제28권1호
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• pp.64-74
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• 2019

Purpose: The purpose of this study was to identify the influencing factors on burnout after analyzing the relationship among clinical nurses' various perfectionism and coping styles. Methods: A descriptive, cross-sectional study was conducted with 200 clinical nurses who had six months or more years of clinical experiences from two general hospitals located in D city. The data were analyzed by t-test, one-way ANOVA, Pearson's correlation coefficients, and stepwise regression analysis using IBM SPSS statistics 23.0 program. Results: The burnout of clinical nurses was positively correlated with socially prescribed perfectionism and negatively correlated with active coping style. Socially prescribed perfectionism was positively correlated with active coping style and passive coping style. Influencing factors on the burnout of clinical nurses were socially prescribed perfectionism (${\beta}=.37$), satisfied work unit (${\beta}=-.64$) and neutral satisfaction of work unit (${\beta}=-.27$), over 40 years of age (${\beta}=-.21$), and active coping style (${\beta}=-.14$). The model consisting of these variables explained 42% of variance of burnout in clinical nurses. Conclusion: Based on the findings of this study developing intervention programs that consider influencing factors such as perfectionism and coping styles is needed to reduce the level of burnout of clinical nurses.

• 한국치위생학회지
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• 제19권4호
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• pp.525-533
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• 2019

Objectives: This research aimed to identify the influential factors that affect the satisfaction of dental hygiene students' clinical training between college and university and contribute to improvement in clinical practice quality. Methods: A self-reported questionnaire was completed by 210 dental clinical hygienists from June 10 to August 30, 2018. Data were analyzed using SPSS 22.0. An independent t-test, one-way ANOVA, Scheffe's post-hoc test, and Pearson's correlation coefficient were employed, and a stepwise multiple regression analysis was performed. Results: Regarding the influential factors of satisfaction with clinical practice among dental hygiene students, in the case of college students, dental hygienist practice instructor dummy, self-efficacy, satisfaction of school life, interpersonal relation was the increasing order. In the case of university students, dental hygienist practice instructors, subjective health, satisfaction with school life, and interpersonal relations was the increasing order. Conclusions: The most influential factor of dental hygiene students' clinical practice satisfaction between college and university was the ability to form interpersonal relationships. Therefore, to increase the satisfaction of dental hygiene students with clinical practice between college and university, external sources and efforts to emphasize internal sources are required.