• Journal of Power Electronics
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• v.13 no.6
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• pp.939-954
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• 2013

The Direct Torque Control (DTC) technique for Permanent Magnet Synchronous Motors (PMSM) is receiving increased attention due to its simplicity and robust dynamic response when compared with other control techniques. The classical switching table based DTC results in large flux and torque ripples in the motors. Several studies have been reported in the literature on classical DTC. However, there are only limited studies that actually discuss or evaluate the classical DTC. This paper proposes, novel switching table / DTC methods for PMSMs to reduce torque ripples. In this paper, two DTC schemes are proposed. The six sector and twelve sector methodology is considered in DTC scheme I and DTC scheme II, respectively. In both DTC schemes a simple modification is made to the classical DTC structure. The two level inverter available in the classical DTC is eliminated by replacing it with a three level Neutral Point Clamped (NPC) inverter. To further improve the performance of the proposed DTC scheme I, the available 27 voltage vectors are allowed to form different groups of voltage vectors such as Large - Zero (LZ), Medium - Zero (MZ) and Small - Zero (SZ), where as in DTC scheme II, all of the voltage vectors are considered to form a switching table. Based on these groups, a novel switching table is proposed. The proposed DTC schemes are comparatively investigated with the classical DTC and existing literatures through theory analysis and computer simulations. The superiority of the proposed DTC method is also confirmed by experimental results. It can be observed that the proposed techniques can significantly reduces the torque ripples and improves the quality of current waveform when compared with traditional and existing methods.

• Biomolecules & Therapeutics
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• v.19 no.4
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• pp.398-410
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• 2011

Over the past few decades, our understanding of the epidemiology and immunopathogenesis of Hodgkin lymphoma (HL) has made enormous advances. Consequently, the treatment of HL has changed significantly, rendering this disease of the most curable human cancers. To date, about 80% of patients achieve long-term disease-free survival. However, therapeutic challenges still remain, particularly regarding the salvage strategies for relapsed and refractory disease, which need further identification of better prognostic markers and novel therapeutic schemes. Although the precise molecular mechanism by which Epstein-Barr virus (EBV) contributes to the generation of malignant cells present in HL still remains unknown, current increasing data on the role of EBV in the pathobiology of HL have encouraged people to start developing novel and specific therapeutic strategies for EBV-associated HL. This review will provide an overview of therapeutic approaches for acute EBV infection and the classical form of HL (cHL), especially focusing on EBV-associated HL cases.

• Journal of Korean Classical Literature and Education
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• no.33
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• pp.45-82
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• 2016

Class, the fundamental unit of school education and the meeting place of teacher and students, plays an important role in study of the subject matter of education. Class criticism is material to the theory or method that helps researchers deeply understand and analyze class phenomena or teachers' actions during a class. In this study, I make a critique on the features of a classic novel class as attempt to expand on new prospects in the field of research on classical literature education. The classic novel class in this class criticism is typical one, which reads the work analytically. Nevertheless, the teacher turns the students' vague repulsion into empathy and helps them appreciate and internalize the work. Students' empathy and response are reflected in the interpreting-centered class because the teacher's insights about the work and experience, knowledge, and method of literature education are projected during the class. Especially, a situation in which the teacher spends a relatively long time narrating the background of the work clearly shows the value and meaning disseminated in a classic novel class. Based on the aforementioned, attempts to collect a variety of cases of a classic novel class and to understand the meaning of these cases have to be part of future research. The research on the attributes of a class such as criticism of classic novels enables us to renew introspection to discover classical literature education.

• (The)Study of the Eastern Classic
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• no.43
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• pp.65-92
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• 2011

, or The Story of Jeonuchi, is a classical Korean novel written at an unknown date by an unknown writer. It has a few different editions presumably because they were printed from a variety of different woodcuts carved in a few dialects. The present study examines The Story of Jeonuchi based on one of its earliest editions collected by the Academy of Korean Studies. Focused on the novel's main ideas of educational value, the author explores effective educational means to teach these ideas to college students. The novel's main ideas with edifying qualities include: alleviating resentment of the people, punishing the greedy, promoting filial piety and loyalty to the sovereign, and antagonism between disloyal forces. And these ideas can be effectively discussed in class using brainstorming, demonstration and logical description. Changing time requires a different approach to understanding and appreciating classical novels. Based on this awareness, the study seeks to find an effective way to teach today's students about literature from a different time. It also stresses that this process involves encouraging the students to logically express their ideas in writing.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.05a
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• pp.377-379
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• 2023

Concept drift detection on data stream is the major issue to maintain the performance of the machine learning model. Since the online stream is to be a function of time, the classical statistic methods are hard to apply. In particular case of seasonal time series, a novel window strategy with Fourier analysis however, gives a chance to adapt the classical methods on the series. We explore the KS-test for an adaptation of the periodic time series and show that this strategy handles a complicate time series as an ordinary tabular dataset. We verify that the detection with the strategy takes the second place in time delay and shows the best performance in false alarm rate and detection accuracy comparing to that of arbitrary window sizes.

• Architectural research
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• v.15 no.1
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• pp.17-23
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• 2013

The purpose of this paper is to reconsider and revaluate Ste. Genevieve Library designed by Henri Labrouste as a criticism of Classicism. Considered as the epitome of the early structural Rationalism the modern historian tried to focus only on the iron structure of the library. Arguably, the structural concern was one of the ideas that the architect wanted to manifest in the library. As a rebel against a view of the Acad$\acute{e}$mie des Beaux-Art the notions of H. Labrouste were radical. He criticized an autistic Classicism with an echoing Claude Perrault's doubt about the myth of classical beauty. These radical ideas firstly showed in his report of the Grand Prix de Rome and must have been developed through several discussions for a novel: Notre-Dame de Paris by V. Hugo. 'Ceci tuera cela', one of the chapter of the novel, was generally known as the death of architecture due to the invention of the printing press around Renaissance period. We, however, consider that even though the historical background of the novel is the Gothic period the ideas, which was discussed with Labrouste, related to the death of architecture was not the architecture itself but classical architecture recomposed during Renaissance period. As the first design work the library must be reflected his ideas, which were developed, and manifested his criticism of the Classicism indirectly.

• BMB Reports
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• v.44 no.6
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• pp.369-374
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• 2011

MHC-I molecules play a critical role in immune surveillance against viruses by presenting peptides to cytotoxic T lymphocytes. Although the mechanisms by which MHC-I molecules assemble and acquire peptides in the ER are well characterized, how MHC-I molecules traffic to the cell surface remains poorly understood. To identify novel proteins that regulate the intracellular transport of MHC-I molecules, MHC-I-interacting proteins were isolated by affinity purification, and their identity was determined by mass spectrometry. Among the identified MHC-I-associated proteins was Tmp21, the human ortholog of yeast Emp24p, which mediates the ER-Golgi trafficking of a subset of proteins. Here, we show that Tmp21 binds to human classical and non-classical MHC-I molecules. The Tmp21-MHC-I complex lacks ${\beta}_2$-microglobulin, and the number of the complexes is increased when free MHC-I heavy chains are more abundant. Taken together, these results suggest that Tmp21 is a novel protein that preferentially binds to ${\beta}_2$-microglobulin-free MHC-I heavy chains.

• BMB Reports
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• v.43 no.9
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• pp.579-583
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• 2010

The adipocyte-derived hormone leptin regulates appetite and bone mass. Recent research demonstrates that reciprocally, osteoblasts have a role in controlling energy metabolism. Several genes expressed in osteoblasts are involved in this process, and one of them is the Esp gene. The remaining genes regulate Esp gene expression. OST-PTP, the protein name of Esp, regulates the carboxylation of osteocalcin secreted from osteoblasts, thus affecting insulin sensitivity and insulin secretion. This review provides evidence for a novel interpretation of the connection between bone and energy metabolism and expands our understanding of the novel physiology of bone beyond its classical functions.

• Archives of Pharmacal Research
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• v.29 no.6
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• pp.464-468
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• 2006

Novel phenyl branched apiosyl nucleosides were synthesized in this study. The introduction of phenyl group in the 4'-position was accomplished by a [3,3]-sigmatropic rearrangement. Apiosyl sugar moiety was constructed by sequential ozonolysis and reductions. The natural bases (cytosine and adenine) were efficiently coupled with an apiosyl sugar by classical glycosyl condensation procedure (persilyated base and TMSOTf). The antiviral activities of the synthesized compounds were evaluated against the HIV-1, HSV-1, HSV-2 and HCMV.

• International journal of advanced smart convergence
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• v.4 no.1
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• pp.154-161
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• 2015

A novel process has successfully been developed by overcoming major difficulties through the elimination of number of process steps involved in the Classical Transesterification reaction during the preparation of Fatty Acid Methyl/Ethyl Ester (FAME.FAEE) called biodiesel. The Classical process with cost intensive process steps such as the utilization of excess alcohol, needing downstream distillation for the recovery and reutilization of excess alcohol/cosolvent, unrecoverable homogenous catalyst which consumes vast quantity of fresh distilled water during the purification of the product and downstream waste water treatment before its safe disposal to the surface water body. The Novel Process FAME/FAEE is produced from any vegetable oil irrespective of edible or inedible variety using sonication energy. The novelty of the finding is the use of only theoretical quantity of alcohol along with a co-solvent and reduced quantity of homogeneous catalyst. Under this condition neither the homogeneous catalyst goes to the FAME layer nor is the distillation needed. The same ester also has been prepared in high pressure high temperature reactor without using catalyst at sub critical temperature. The quality of prepared biodiesel without involving any purification step meets the ASTM standards. Blended Biodiesel with Common Diesel Fuel (CDF) and FAME is prepared, characterized and used as fuel in the Kirloskar make CI Engines. The evaluation of the engine performance result of pure CDF, B05 biodiesel, B10 biodiesel of all types of biodiesel prepared by using the feedstock of Soybean (Glycine max) and Karanja (Pongamia pinnate) oil along with their mixed oil provides useful information such as brake power, brake thermal efficiency, brake specific fuel consumption, etc, and established it as ideal fuel for unmodified CI engine.