• Korean Journal of Community Nutrition
• /
• v.3 no.3
• /
• pp.397-409
• /
• 1998

The purposes of this study were to investigate the effects of drug use & the health-related habits(alcohol drinking, smoking and exercise) on the nutritional status of elderly. subjects were 362 free-living elderly aged over 65(male 131, female 231) in Chungbuk area. Interviews with questionaire on drug use, health-related habits, and nutrient intakes, anthropometric measurement and biochemical blood test were carried out from August to October in 1996. Energy intakes of the males who used drug were lower than those of males who did not use any drug, while energy intakes of the females who used drug were higher than those of females who did not. In biochemical indices, LDL-cholesterol level of the males who used drug was higher than that of males who did not have drug. serum triglycerides, VLDL-cholesterol and obesity degree(BMI & TS) of the females who used drug were higher than those of females who did not have drug. Alcohol drinking, smoking and exercise habits of the elderly who used drug had little effects on the nutrient intakes while those habits had considerable effects on biochemical indices and obesity degree. Among drug users, male drinkers showed higher triglycerides & HDL-cholesterol level, and female drinkers showed higher triglycerides and lower total cholesterol and LDL-cholesterol level, compared to non drinkers. Among female drug users, smokers showed lower body mass index(BMI) compared to non smokers. Males and females who had both drinking and smoking habits showed higher serum triglycerides and VLDL-cholesterol level. Especially females who had both drinking and smoking habits showed lower BMI & Tricep skinfold thickness compared to those who had netiher drinking nor smoking habits.

• Journal of the East Asian Society of Dietary Life
• /
• v.7 no.2
• /
• pp.181-198
• /
• 1997

The purpose of this study was to investigated relationship between heath status and food preference of male and fermale adults who live in Iksan City, Cheonbuk, Korea. The subjects consisted of 96 male and 93 fermale adults were aged 20 to 70 years old. Each subject was interviewed to get information of food preference. Blood samples were taken concentration of serum in hemoglobin, glucose, total cholesterol, GOT(glutamic oxaloacetic transaminase), GPT(glutamic pyruvic transaminase) were measured. The results obtained were as follows: Among the food preference were like, dislike and ordinary answered to male and fermale adults the normal average of serum concentration with hemoglobin level showed 15.4, 14.2, 15.5, 12.9, 15.8 and 13.2g/dl, glucose level showed 85.8, 86.1, 87.5, 88.1, 87.9 and 86.1mg/dl, total cholesterol level showed 183.1, 185.0, 172.4, 193.5, 181.2 and 184.0mg/dl, GOT level showed 4.8, 23.4, 24.8, 23.9, 24.9 and 21.7ppm, GPT level showed 22.7, 20.2, 26.3, 18.5, 22.5 and 18.4ppm respectively. The abnormal average of serum concentration with hemoglobin level showed 11.1, 10.8, 12.2, 11.3, 12.5 and 11.0g/dl, abnormal glucose level showed 155.7 168.5, 166.2, 134.1, 124.1, 130.1, abnormal total cholesterol level showed 260.3, 273.7, 255.2, 286.5, 255.9 and 251.8mg/dl, abnormal GOT level showed 58.8, 66.8, 51.8, 50.3, 51.2 and 51.0ppm abnormal GPT level showed 54.3, 48.6, 51.3, 50.2, 53.2 and 45.5ppm respectively.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.24 no.4
• /
• pp.502-509
• /
• 1995

In other to investigate the hypolipidemic effect of dry edible leaves on serum lipids, four kinds of powdered leaves(persimmom, mulberry, perilla, and soy bean) were added to experimental diets at the levels of 5%(w/w). The diets were fed to 30 male Sprague-Dawley rats, aged 4 weeks and weighing 60$\pm$5g, for 3 weeks. Food intake was the largest in Group 1(control), with 5% of cellulose powder, while food efficiency was the highest in Group 2(persimmon). Total cholesterol level in serum was lower in Group 5(soybean) and Group 4(perilla) than the other groups. In comparison with Group 1, HDL-cholesterol level was very high in Group 4 and atherogenic index was low in Groups 4 and 5. Free cholesterol level was the highest in Group 2, and was the lowest in Group 1. Both LDL and LDL-cholesterol levels were the lowest in Group 1, while they were very high in Groups 2 and 3(mulberry). Triglyceride level was the lowest in Group 4, and the highest in Group 1. Except Group 3, all groups had lower phospholipid level than Group 1. Compared with Group 1, calcium level in serum was low in Groups 3, 4 and 5, magenesium level was low in Groups 2, 3 and 5, phosphate level was high in Group 4, and iron level was exceptionally low in Groups 4 and 5. In conclusion, Group 4(perilla) and Group 5 (soybean) showed a favorable effect in atherogenic index and serum levels of various lipids.

• Journal of Nutrition and Health
• /
• v.22 no.1
• /
• pp.42-53
• /
• 1989

The research was designed to study the effect of different fat sources and levels on Body lipid metabolizm and immune responses in Sprague-Dawely strain male rats. These effect of different fat sources compared with sesame Oil, Perilla oil and Beet tallow. Fat sources were divided into 3 groups respectively 7%, 15%, 30% fat level on diet weight basis. The experimental period was 54days. 1) The body weight gain was significantly low in NF group. In Sesame oil group and perilla oil group, low fat level groups were higher than medium, high fat level groups. But in Beef tallow group, high fat level groups were higher than low and Medium groups. 2) The weight of liver, kidney and epididymal fat ped tend to increse with increasing body weight. 3) The contents of triglyceride and total lipid in serum were significantly different with dietary fat sources and Perilla oil group was the lowest. 4) The contents of triglyceride and total lipid in liver were significantly different with dietary fat levels and high fat level group was higher than low fat level group. 5) Perilla oil group, compared with Beef tallow group, showed the higher excretion of cholesterol through feces and the higher deposit of cholesterol in liver. Therefore serum cholesterol level of Perilla oil group was lower than that of Beef tallow group. But eventhough Sesame oil is vegetable oil, Sesame oil did not showed an effect like Perllia oil on serum cholesterol level. 6) Weight of thymus decreased with fat levels particularly in vegetale oil. And it had on effect on mitogen response, mitogen response decreased with fat level in vegetable oil. But in Beef tallow, there was no difference in fat level.

• Journal of Life Science
• /
• v.20 no.10
• /
• pp.1525-1531
• /
• 2010

The principal objective of this study was to investigate the effects of silkworm sericin extract supplementation on the improvement of lipid compositions, blood glucose levels and enzyme activities in the serum of dyslipidemic rats. The rats were fed the experimental diet for 5 weeks. Concentrations of total cholesterol, atherosclerotic index, LDL-cholesterol, triglyceride (TG), phospholipid (PL), free cholesterol, cholesteryl ester ratio and blood glucose in serum were higher in the dyslipidemic group (group HCW) and cholesterol-plus-silkworm sericin extract intake group (group HCS) than those in the control group (group BW, basal diet-plus-water). However, the concentrations of total cholesterol, atherosclerotic index, LDL-cholesterol, TG, PL, free cholesterol, cholesteryl ester ratio and blood glucose level in serum were lower in group HCS than those in group HCW. On the other hand, the HDL-cholesterol level and the ratio of HDL-cholesterol to total cholesterol in group HCS were higher than in group HCW. The activities of alkaline phosphatase (ALP) and aminotransferase (AST & ALT) in serum were lower in group HCS than in the dyslipidemic group HCW. From the above results, it was suggested that silkworm sericin extract intake was effective in the prevention and improvement of lipid components, blood glucose level and enzyme activities in the sera of dyslipidemic rats.

• Journal of the Korean Society of Fashion and Beauty
• /
• v.6 no.2
• /
• pp.87-90
• /
• 2008

Background: It has been debated that serum lipid levels of patients with xanthelasma are higher than those of normal persons. In Korean literature, there are two reports of this. Objective: Our purpose was to review the findings in patients with xanthelasma and compare the patients to normal persons in respect of serum lipid levels. Methods: Fifty-one patients with xanthelasma were reviewed. Results: Mean age was 51 years in man and 51 years in woman. The ratio of male to female patients was 1:2.7. Significant difference of serum HDL-cholesterol level was found between patients with normal lipid level and normolipidemic control subjects. Conclusion: Xanthelasma palpebrarum occurs frequently in middle-aged women and HDL-cholesterol level of patients with xanthelasma was lower than normolipidemic control subjects.

• Korean Journal of Clinical Laboratory Science
• /
• v.43 no.4
• /
• pp.205-209
• /
• 2011

Gestational diabetes mellitus(GDM) is likely to develop type 2 diabetes mellitus, cardiovascular disease, metabolic syndrome after delivery. Infants of diabetic women have higher incidence of congenital malformations than those of non-diabetic women. This study was performed to determine elevation factors associated with increased blood glucose in 350 pregnant women. Subjects were examined in June, 2011 to September, 2011 in Geongnam province. Fasting blood glucose, total cholesterol, triglyceride levels were measured by Olympus AU 680, and their body mass index (BMI) calculated. The mean total cholesterol levels were 223.22 mg/dL, triglyceride 188.38 mg/dL, and fasting blood glucose 100.18 mg/dL. Serum glucose level was significantly higher in the age group of 40 years($109.51{\pm}16.26mg/dL$) than 20 years and 30 years. And increase in triglyceride(>250 mg/dL) was significantly related to high blood glucose level($110.83{\pm}24.78mg/dL$), and increase in BMI(>26) was significantly related to high blood glucose level($114.03{\pm}27.09mg/dL$). However, cholesterol levels were not significantly related to high blood glucose level. In conclusion, the significant elevation factors in relation to the glucose levels were age, triglyceride, and BMI.

• Preventive Nutrition and Food Science
• /
• v.2 no.2
• /
• pp.149-154
• /
• 1997

The ability of exercise and buckwheat diet to modify plasma glucose and cholesterol levels in streptozotocin-induced diabetic rats has been studied. Diabetic rats were fed corn starch as a control diet or buckwheat as an experimental diet for 4 weeks. One group of rats were exercise-trained to swim for 60 min/day, 6 days a week. Plasma glucose levels of sedentary rats both on the control diet and on the buckwheat diet were significantly increased from 367.0$\pm$33.6 mg/dl to 545.0$\pm$38.7 mg/dl and from 380.3$\pm$18.9 mg/dl to 540.5$\pm$36.6 mg/dl, respectively. However, this large increase of plasma glucose was not seen in exercised rats on the buckwheat diet (from 345.0$\pm$25.6 mg/dl to 391.4$\pm$34.7 mg/dl). The total plasma cholesterol level was not affected by either diet or exercise. The HDL-cholesterol level tends to increase due to the buckwheat diet or an exercise, but not with a significant increase. Our results suggest that the buckwheat diet is beneficial in lowering the plasma glucose level only when diabetic rats ar exercised.

• The Korea Journal of Herbology
• /
• v.25 no.3
• /
• pp.81-90
• /
• 2010

Objectives : The present study purposed to compare the effects of Melandrii Herba and Vaccariae Semen, which are used as Wang-Bul-Yu-Haeng(王不留行) with vasodilatory effect in Korea and China, respectively, on hyperlipidemia. Methods : We applied the water extract of Melandrii Herba and Vaccariae Semen to rats with hyperlipidemia induced by high-cholesterol diet and high-fructose diet and evaluated their effects. Results : While Vaccariae Semen had significant effect on the reduction of the levels of total cholesterol, LDL-cholesterol, free cholesterol, and the activation of ALT, the application of Melandrii Herba had no significant effect on the levels of total cholesterol, LDL-cholesterol, free cholesterol, neutral fat, and free fatty acid, and the activation of AST. For the rats with hypertriglyceridemia, Vaccariae Semen reduced the levels of neutral fat and total cholesterol, but did not significantly reduce the level of free fatty acid and the activation of AST and ALT. The application of Melandrii Herba did not have any significant effect on the levels of neutral fat, total cholesterol, and free fatty acid, and the activation of AST and ALT, but it increased the level of HDL cholesterol. Conclusion : Vaccariae Semen showed a possibility as a remedy for hyperlipidemia, but Melandrii Herba did not show any significant effect. Thus, based on such a difference in remedial effect between Melandrii Herba and Vaccariae Semen, they need to be distinguished in clinical application.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.17 no.4
• /
• pp.1092-1096
• /
• 2003

This study was carried out to investigate the clinical effects of Tongbiyeum(TBY) ₂on hyperlipidemia. The hyperlipidemia of rats was induced by feeding high cholesterol diet for 4 weeks. We checked serum lipids and body weight weekly for 4 weeks. After the termination of treatment, we measured liver weight and observed histopathological change. We compared result of TBY group with control group. Thereafter, we made a study of 37 hyperlipidemic patients who visited us, the oriental medical center Daejeon and cheongju of Daejeon University, from November, 2001 to April, 2002. After administering TBY for 1 month, we followed up their total cholesterol, triglyceride and HDL-Cholesterol levels. The results were as follows; TBY treatment inhibited the liver weight gain induced by high cholesterol diet as compared with control group. TBY treatment inhibited lipid droplet accumulation and apoptotic change in liver as compared with control group. TBY treatment significantly inhibited the increasing of serum triglyceride and total cholesterol levels induced by high cholesterol diet as compared with control group but not affect HDL-cholesterol level. After administering TBY, the serum total cholesterol, triglyceride and LDL-cholesterol levels of hyperlipidemic patients were decreased significantly. After administering TBY, the serum HDL-Cholesterol level of hyperlipidemic patients had no significant changes. According to above mentioned results, we can infer that TBY has hypolipidemic effect to be applicable to artheriosclerosis.