• Title/Summary/Keyword: Choi Chi Won

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Isolation and Physicochemical Properties of Carotenoid Pigments from Orange Peels (감귤 과피 Carotenoid 색소의 분리 및 이화학적 성질)

  • Shim, Ki-Hwan;Sung, Nack-Kie;Kan, Kap-Suk;Choi, Jine-Shang;Jang, Chi-Won
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.1
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    • pp.143-149
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    • 1994
  • Carotenoids isolated from orange peels were determined physicocohemical properties with TLC, UV-spectrophotometer and HPLC etc., and the results were as follows . Maximum absorption wavelength of the isolated carotenoids was 415nm when the result was similar to $\beta$-carotene as 423nm. Eight spots were obtianed from TLC, and identified lutein, lycopene, $\alpha$-carotene and $\beta$-carotene with HPLC. The effect pH during the storage period of isolate carotenoids, the period when the amount of pigment retention was over 50% in pH 5, 6 and 7 , after 10 days . The amount of pigment retention was lower in control than in treatment of sugars such as fructose, glucose and sorbitol , but sucrose was similar to the control, Isolated carotenoids were stable to ascorbic acid, and the amount of pigment retention was over 70% after 10 days. The amount of pigment retention in the effect oforganic acid was higher in treated citric acid , lactic acid and tartaric acid than in control, but lower in treated maleic acid and succinic acid. Isolated carotenoids were stable at 50 $^{\circ}C$, and the amount of pigment retention was over 50% at 10$0^{\circ}C$.

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Comprehensive Analysis for Risk Factors of Lower Extremity Amputation as a Treatment of Complicated Diabetic Foot (당뇨 합병증으로 인한 하지 절단술의 위험 인자의 포괄적 분석)

  • Chung, Hyung-Jin;Bae, Su-Young;Min, Byoung-Kwon;Park, Jae-Gu;Kam, Min-Cheol;Choi, Ji-Won
    • Journal of Korean Foot and Ankle Society
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    • v.16 no.4
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    • pp.257-264
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    • 2012
  • Purpose: The diabetic foot lesions are intractable, and aggravation often leads to amputation. None or minor amputation group was treated debridement or toe amputation and major amputation group was treated Ray, Lisfranc, Chopart, Below Knee and Above Knee amputation. We investigate the risk factors for major limb amputations among patients with diabetic foot lesion. Materials and Methods: The subjects were 73 diabetic foot lesion patients (83 diabetic foot lesions) treated at our department from January 2006 to December 2010. Non or Minor amputation group of 44 cases were treated with debridement or toe amputation. Major amputation group of 39 cases were treated with Ray, Lisfranc, Chopart, below or above Knee amputation. We investigated socioeconomic factors, diabetes mellitus related factors and wound related factors and laboratory factors. Statistical analysis was done by Students t-test, Chi-square test, Mann-Whitney's U test. Results: In our analysis, wound size, wound classification (Wagner classification, Brodsky classification), white blood cell counts, polymorphoneuclear neutrophil percentage, hemoglobin, C-reactive protein and albumin were risk factors for major amputation (p<0.05). Conclusion: Low education level, nutritional condition, premorbid activity level and progressed wound condition were observed in major amputation group compared with non or minor amputation group. In the major amputation group, higher white blood cell count, C-reactive protein level and lower albumin level were observed. Together with maintenance of adequate nutritional condition, early detection of lesions and foot care for early treatment is important. Therefore, active investigation with full risk evaluation of vascular complication is also important.

Geoacoustic Characteristics of P-Wave Velocity in Donghae City - Ulleung Island Line, East Sea: Preliminary Results (동해시-울릉도 해저 측선에서의 P파 속도 지음향 특성: 예비 결과)

  • Ryang, Woo-Hun;Kwon, Yi-Kyun;Jin, Jae-Hwa;Kim, Hyun-Tae;Lee, Chi-Won;Jung, Ja-Hun;Kim, Dae-Choul;Choi, Jin-Hyuk;Kim, Young-Gyu;Kim, Sung-Il
    • The Journal of the Acoustical Society of Korea
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    • v.26 no.2E
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    • pp.44-49
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    • 2007
  • Donghae City - Ulleung Island Line (DC-UI Line) is a representative line for underwater and geoacoustic modeling in the middle western East Sea. In this line, an integrated model of P-wave velocity is proposed for a low-frequency range target (<200 Hz), based on high-resolution seismic profiles (2 - 7 kHz sonar and air-gun), shallow and deep cores (grab, piston, and Portable Remote Operated Drilling), and outcrop geology (Tertiary rocks and the basement on land). The basement comprises 3 geoacoustic layers of P-wave velocity ranging from 3750 to 5550 m/s. The overlying sediments consist of 7 layers of P-wave velocities ranging from 1500 to 1900 m/s. The bottom model shows that the structure is very irregular and the velocity is also variable with both vertical and lateral extension. In this area, seabed and underwater acousticians should consider that low-frequency acoustic modeling is very range-dependent and a detailed geoacoustic model is necessary for better modeling of acoustic propagation such as long-range surveillance of submarines and monitoring of currents.

Comparative Genomics Study of Interferon-$\alpha$ Receptor-1 in Humans and Chimpanzees

  • Kim, Il-Chul;Chi, Seung-Wook;Kim, Dae-Won;Choi, Sang-Haeng;Chae, Sung-Hwa;Park, Hong-Seog
    • Genomics & Informatics
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    • v.3 no.4
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    • pp.142-148
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    • 2005
  • The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human chromosome 21 (HSA21), we have identified 15 orthologs having indel in their coding sequences. Among them, interferon-${\alpha}$ receptor-1 gene (IFNAR1), an immuneresponse-related gene, is subjected to comparative genomic analysis. Chimpanzee IFNAR1 showed the same genomic structure as human IFNAR1 (11 exons and 10 introns) except the 3 bp insertion in exon 4. The sequence alignment of IFNAR1 coding sequence indicated that 'ISPP' amino acid sequence motif is highly conserved in chimpanzee and other animals including mouse and chicken. However, the human IFNAR1 shows that one proline residue is missing in the sequence motif. The homology modeling of the IFNAR1 structures suggests that the proline deletion in human IFNAR1 leads to the formation of the following ${\alpha}$-helix, whereas two sequential prolines in chimpanzee IFNAR1 inhibit it. As a result, human IFNAR1 may adopt a characteristic structure distinct from chimpanzee IFNAR1. This human specific trait could contribute to specific immune response in the most optimized manner for humans. Further molecular biological studies on the IFNAR1 will help us to gain insights into the molecular implication of species-specific host-pathogen interaction in primate evolution.

Synthesis and Oxygen Reduction Reaction Characteristics of Multi-Walled Carbon Nanotubes Supported PtxM(1-x) (M = Co, Cu, Ni) Alloy Catalysts for Polymer Electrolyte Membrane Fuel Cell (다중벽 탄소 나노 튜브에 담지한 PtxM(1-x)(M = Co, Cu, Ni) 합금촉매의 제조 및 고분자 전해질 연료전지에서 산소환원 특성)

  • Jung, Dong-Won;Park, Soon;Ahn, Chi-Yeong;Choi, Seong-Ho;Kim, Jun-Bom
    • Korean Journal of Materials Research
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    • v.19 no.12
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    • pp.667-673
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    • 2009
  • The electrocatalytic characteristics of oxygen reduction reaction of the $PtxM_{(1-x)}$ (M = Co, Cu, Ni) supported on multi-walled carbon nanotubes (MWNTs) have been evaluated in a Polymer Electrolyte Membrane Fuel Cell (PEMFC). The $Pt_xM_{(1-x)}$/MWNTs catalysts with a Pt : M atomic ratio of about 3 : 1 were synthesized and applied to the cathode of PEMFC. The crystalline structure and morphology images of the $Pt_xM_{(1-x)}$ particles were characterized by X-ray diffraction and transmission electron microscopy, respectively. The results showed that the crystalline structure of the Pt alloy particles in Pt/MWNTs and $Pt_xM_{(1-x)}$/MWNTs catalysts are seen as FCC, and synthesized $Pt_xM_{(1-x)}$ crystals have lattice parameters smaller than the pure Pt crystal. According to the electrochemical surface area (ESA) calculated with cyclic voltammetry analysis, $Pt_{0.77}Co_{0.23}$/MWNTs catalyst has higher ESA than the other catalysts. The evaluation of a unit cell test using Pt/MWNTs or $Pt_xM_{(1-x)}$/MWNTs as the cathode catalysts demonstrated higher cell performance than did a commercial Pt/C catalyst. Among the MWNTs-supported Pt and $Pt_xM_{(1-x)}$ (M = Co, Cu, Ni) catalysts, the $Pt_{0.77}Co_{0.23}$/MWNTs shows the highest performance with the cathode catalyst of PEMFC because they had the largest ESA.

Effectiveness of Hwang-gu acupuncture treatment in hypertension patients; case report (황구침법(黃丘鍼法)을 이용한 고혈압 환자의 혈압강하 효과에 대한 증례보고)

  • Han, Chang-Hyun;Hwang, Chi-Won;Shin, Mi-Suk;Shin, Seon-Hwa;Choi, Sun-Mi
    • Korean Journal of Acupuncture
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    • v.23 no.3
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    • pp.37-50
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    • 2006
  • Objectives : The aim of the study was to investigate the antihypertensive effect of Hwang-gu Acupuncture in hypertensive patients. Methods : We measured the blood pressure of the patients who were admitted in the Oriental Medical Clinic of Brother from 25th November 2005 to 27th March 2006. We included the patients only in case of the systolic blood pressure was over 140mmHg or diastolic blood pressure was over 90mmHg, Twenty two patients were treated by Hwang-gu Acupuncture. In order to evaluate the effect of the Hwang-gu Acupuncture, the blood pressure was measured before and after Acupuncture procedure total 4 times, 10times. Results : There were a significant decrease in the systolic blood pressure and significant decrease in the diastolic blood pressure by Hwang-gu Acupuncture 4 times. The effect of Hwang-gu Acupuncture by measurement time on blood pressure were follows: In a systolic blood pressure was gradually deceased significantly from 1st to 4th but diastolic blood pressure was significantly decreased after 2nd and 4th only. Conclusions : These results suggest that Hwang-gu Acupuncture is effective in decreasing the systolic and diastolic blood pressure.

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Effects of school-based depression awareness education program for adolescent (학교를 기반으로 한 청소년 우울증 인식개선교육 프로그램의 효과)

  • Choi, Ran;Yim, Hyeon Woo;Jo, Sun-Jin;Bang, Myeong Hee;Ji, Yu Na;Lee, Won Chul
    • Korean Journal of Health Education and Promotion
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    • v.32 no.1
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    • pp.57-65
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    • 2015
  • Objectives: This study was conducted to evaluate the impact of a School-based Depression Awareness Education Program on depression knowledge and help-seeking orientation for adolescent. Methods: The students of two high schools were allocated to the intervention (n=221) or control group (n=223) in this cluster-randomized trial. The school-based depression awareness education was a 3-hour program. The intervention group received pre, post and follow up tests while the control group received pre and follow up tests after two months. Depression knowledge, attitude to friends'depression, and help-seeking for professional assistance was evaluated at each test. Differences in the two month change between the intervention and control groups were analyzed by t-test or chi-square test. Results: There were positive changes in depression knowledge, response to friend's depression, and attitude to professional help-seeking in the post test compared to the pretest among intervention group. Improvement of depression knowledge was greater in the intervention group than in the control group (P=0.011), but there were no significant differences in response to friend's depression (P=0.268) or help-seeking orientation (P=0.263) after two months. Conclusions: School-based Depression Awareness Education resulted in significant positive changes in depression knowledge in high school students, but made no attitudes difference to professional help-seeking.

Factors Related to Smoking Behavior among High School Students (일 지역 고등학생의 흡연경험 관련 요인)

  • Choi, Won-Hee;Je, Mi-Soon;Lee, Sam-Soon
    • Journal of Korean Public Health Nursing
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    • v.24 no.2
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    • pp.226-236
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    • 2010
  • Purpose: The study investigated factors related to the smoking behavior among 639 high school students in Geoje, Korea. Methods: Data collected by self-reported questionnaires was analyzed by the SPSS WIN 14.0 program with Chi-test, t-test, and multiple logistic regression analysis. Results: Smoking behavior differed by gender (p=.002), school type (p=.001), experience with alcohol consumption (p=.005), family harmony (p=.003), father's smoking (p=.001), academic achievement (p=.010), self-esteem (p=.010), stress (p=.004), and attitude to smoking (p=.0001). Smoking behavior was significantly associated with gender (odds ratio (OR)=0.66, 95% confidence interval (CI)=0.46-0.95), school type (OR=1.52, 95% CI=1.03-2.23), experience with alcohol consumption (OR=0.56, 95%CI= 0.39-0.82), academic achievement (OR=1.98, 95-I=1.20-3.29), attitude to smoking (OR= 0.76, 95%CI=0.69-0.84) and father's smoking (OR=1.59, 95%CI=1.11-2.29). Conclusion: Anti-smoking programs for high school students should especially consider those at higher risk (males in vocational high school with no drinking experience of drinking, lower academic achievement, favorable attitude to smoking, and whose fathers smoke). Community efforts to reduce adult smoking would be advantageous.

The Study of Plasma Display Panel for Digital Radiography Detector (플라즈마 디스플레이 판넬의 디지털 방사선 검출기 적용을 위한 연구)

  • Cho, Sung-Ho;Kang, Sang-Sik;Cha, Byung-Ryul;Kim, So-Yeong;Choi, Chi-Won;Yun, Min-Seok;Kwan, Chul;Nam, Sang-Hee
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.29-29
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    • 2007
  • TFT, LCD, OLED, PDP and FED를 비롯한 많은 디스플레이 장치가 개발, 연구되고 있으며, 이러한 디스플레이 장치에 대한 수 많은 application 연구 또한 진행되고 있다. TFT-LCD는 이미 방사선 검출기로서 연구가 오랜전에 연구되어 상용화가 되었으며, LCD는 XLV로서 적용을 위한 연구가 진행되고 있으며, 그 외 수 많은 디스플레이 장치에 대한 활발한 연구가 진행되고 있는 실정이다. PDP는 대면적, 낮은 제작 비용, 높은 contrast의 이점으로 디스플레이 장치로서 활발한 연구가 진행되고 있다. 본 논문에서는 PDP를 처음으로 방사선 검출기로 적용하기 위한 연구를 수행하였다. 제작된 7 인치 AC-PDP는 다양한 가스종류 및 압력을 가진 300um의 pixel pitch룰 가진 3 전극 구조로서, coplanar readout과 대항형 readout을 통해 신호량을 분석하였다. 결과 50-100Kvp의 진단 영역의 X-ray energy에서 줄은 민감도와 훌륭한 선형성을 보였으며, 가스 종류 및 압력, 신호 검출방식에 따라 각각 다른 특성을 보였다. 이는 PDP 내 X선과의 Interaction, R/O method. Material에 강하게 의존한다.

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The study on characteristics of panic disorder through clinical and personality scales in MMPI of patients with Panic disorder (MMPI 임상척도와 성격척도를 통해 살펴 본 공황장애 환자의 특성에 대한 연구)

  • Kim, Jin-Hyung;Gug, Yun-Jai;Choi, Sung-Youl;Kim, Tae-Heon;Lyu, Yeoung-Su;Kang, Hyung-Won
    • Journal of Oriental Neuropsychiatry
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    • v.16 no.1
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    • pp.129-142
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    • 2005
  • Objectives : This study was to investigate MMPI profile on clinical scales and personality scales of Panic Disorder patients. Methods : Thirty eight Panic Disorder patients and twenty eight normal control were administered the MMPI. Experimental design was done by nonequivalent control group and statistics were crosstabs, chi-square test, ANOVA, t-test and cluster analysis Results and Conclusions : 1. The MMPI clinical scales profile of Panic Disorder patients was neurotic profile of 2-7 type. Panic Disorder patients was elevated the other scales except L, K, Mf and Ma scales for control group. 2. A result of grouping MMPI in Panic Disorder patients, we could classify into 3 different groups. Group 1 is a profile of conversional neurosis. Group 2 is a normal proflie. Group 3 is a proflie of $'{\Lambda}'$ type neurosis. 3. Personality characteristics in Panic Disorder patients was lowed scores in HST, NAR scales, elevated the other scales except ANT scale. Specially in PAG, AVD scales showed high scores.

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