• Proceedings of the Korea Water Resources Association Conference
• /
• 2005.09b
• /
• pp.1313-1314
• /
• 2005

• International Journal of Fluid Machinery and Systems
• /
• v.9 no.3
• /
• pp.265-276
• /
• 2016

Energy systems working coherently in different conditions may not have a specific design which can provide optimal performance. A system working for a longer period at lower efficiency implies higher energy consumption. In this effort, a methodology demonstrated by a jet pump design and optimization via numerical modeling for fluid dynamics and implementation of an evolutionary algorithm for the optimization shows a reduction in computational costs. The jet pump inherently has a low efficiency because of improper mixing of primary and secondary fluids, and multiple momentum and energy transfer phenomena associated with it. The high fidelity solutions were obtained through a validated numerical model to construct an approximate function through surrogate analysis. Pareto-optimal solutions for two objective functions, i.e., secondary fluid pressure head and primary fluid pressure-drop, were generated through a multi-objective genetic algorithm. For the jet pump geometry, a design space of several design variables was discretized using the Latin hypercube sampling method for the optimization. The performance analysis of the surrogate models shows that the combined surrogates perform better than a single surrogate and the optimized jet pump shows a higher performance. The approach can be implemented in other energy systems to find a better design.

• Journal of Preventive Medicine and Public Health
• /
• v.57 no.2
• /
• pp.157-166
• /
• 2024

Objectives: Children with disabilities may exhibit a multitude of symptoms, and treatment requires a multidisciplinary approach for a satisfactory outcome. Lack of awareness among physicians, lack of referral, and lack of inter-sectoral coordination have hindered paediatric practice in Tamil Nadu, a state in India with a striking childhood disability rate that warrants a timely interdisciplinary approach. However, the perspectives of paediatricians on paediatric physiotherapy are unknown. The aim of the study was to investigate the perspectives of practicing paediatric physicians in Chennai on the role of physiotherapy in paediatrics. Methods: For an in-depth exploration, qualitative semi-structured interviews were conducted in person with 10 paediatricians. Audio from the sessions was recorded and transcribed, and data saturation was achieved through iterative analysis. Results: A grounded theory analysis of the results yielded 5 domains under which the perspectives and expectations of the physicians were described, along with the barriers experienced by patients' parents as explained by their paediatrician. The responses highlighted deficits in awareness, structural support, accessibility and direct communication between physicians and physiotherapists. Conclusions: Paediatric physicians have different opinions, and some ignorance persists concerning paediatric physiotherapy. This study warrants a proper structure of the paediatric rehabilitation unit and regular interdisciplinary meetings and focus group discussions to increase access for parents and improve patient outcomes.

• Carbon letters
• /
• v.11 no.1
• /
• pp.13-21
• /
• 2010

Coconut shell activated carbon (CSAC) was investigated for its ability in the removal of two neutral chlorinated organic compounds, namely trichloroethylene (TCE) and dichloromethane (DCM) from aqueous solution using a packed bed column. The efficiency of the prepared activated carbon was also compared with a commercial activated carbon (CAC). The important design parameters such as flow rate and bed height were studied. In all the cases the lowest flow rate (5 mL/min) and the highest bed height (25 cm) resulted in maximum uptake and per cent removal. The experimental data were analysed using bed depth service time model (BDST) and Thomas model. The regeneration experiments including about five adsorption-desorption cycles were conducted. The suitable elutant selected from batch regeneration experiments (25% isopropyl alcohol) was used to desorb the loaded activated carbon in each cycle.

• Journal of Integrative Natural Science
• /
• v.6 no.2
• /
• pp.100-103
• /
• 2013

Using computational approaches we can dock small molecules into the structures of Macromolecular targets and then score their potential complementarity to binding sites is widely used in hit identification and lead optimization techniques. This review seeks to provide the application of docking in structure-based drug design (binding mode prediction, Lead Identification and Lead optimization), and also discussed how to manage errors in docking methodology in order to overcome certain limitations of docking and scoring algorithm.

• Asian Journal of Innovation and Policy
• /
• v.7 no.3
• /
• pp.489-510
• /
• 2018

Institution-based Technology Business Incubators are on the rise in India, as a means of promoting innovation-based tech start-up ecosystems, due to increased policy initiatives. Against this background, we have traced the origin and process of building a start-up ecosystem in IIT Madras, Chennai of India, based on semistructured interviews held with the stakeholders of the ecosystem. Subsequently, we have ascertained the key components of IIT Madras start-up ecosystem, and the process of incubation comprising pre-incubation, incubation and post-incubation phases. Finally, we have derived the key lessons from the ecosystem development experience and incubation process which enable generation of start-ups from both students and faculty, apart from alumni and ex-industry executives. Though this ecosystem model has emerged over a period of time through learning and experience, the ecosystem is able to generate more than 100 start-ups, majority of them being from students and faculty. Thus, the evolved start-up ecosystem of IIT Madras is able to generate faculty-supported and student-led entrepreneurship successfully.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.7 no.4
• /
• pp.878-894
• /
• 2013

Secure multimedia multicast applications involve group communications where group membership requires secured dynamic key generation and updating operations. Such operations usually consume high computation time and therefore designing a key distribution protocol with reduced computation time is necessary for multicast applications. In this paper, we propose a new key distribution protocol that focuses on two aspects. The first one aims at the reduction of computation complexity by performing lesser numbers of multiplication operations using a ternary-tree approach during key updating. Moreover, it aims to optimize the number of multiplication operations by using the existing Karatsuba divide and conquer approach for fast multiplication. The second aspect aims at reducing the amount of information communicated to the group members during the update operations in the key content. The proposed algorithm has been evaluated based on computation and communication complexity and a comparative performance analysis of various key distribution protocols is provided. Moreover, it has been observed that the proposed algorithm reduces the computation and communication time significantly.

• Journal of Power Electronics
• /
• v.13 no.4
• /
• pp.656-668
• /
• 2013

This paper presents a wavelet-fuzzy based controller for indirect field oriented control of three-phase induction motor drives. The discrete wavelet transform is used to decompose the error between the actual speed and the command speed of the induction motor drive into different frequency components. The transformed error coefficients along with the scaling gains are used for generating the control component of the motor. Self-tuning fuzzy logic is used for online tuning of the scaling gains of the controller. The proposed controller has the ability to meet the speed tracking requirements in the closed loop system. The complete indirect field oriented control scheme incorporating the proposed wavelet-fuzzy based controller is investigated theoretically and simulated under various dynamic operating conditions. The simulation results are compared with a conventional proportional integral controller and a fuzzy based controller. The speed control scheme incorporating the proposed controller is implemented in real time using a digital processor control board. Simulation and experimental results validate the effectiveness of the proposed controller.

• Bulletin of the Korean Chemical Society
• /
• v.31 no.12
• /
• pp.3668-3674
• /
• 2010

Mesoporous SBA-15 was synthesized using tetraethylorthosilicate (TEOS) as the silica source and Pluronic (P123) as the structure-directing agent. The defective Si-OH groups present in SBA-15 were successively grafted with 3-chloropropyltrimethoxysilane (CPTMS) followed by tris-(2-aminoethyl) amine (TAEA) and/or tetraethylenepentamine (TEPA) for effective immobilization of silver nanoparticles. Grafting of TAEA and/or TEPA amine and immobilization of silver nanoparticles inside the channels of SBA-15 was verified by XRD, TEM, IR and BET techniques. The silver nanoparticles immobilized on TAEA and /or TEPA grafted SBA-15 was subjected for electrocatalytic reduction of hydrogen peroxide ($H_2O_2$). The TEPA stabilized silver nanoparticles show higher efficiency for reduction of $H_2O_2$ than that of TAEA, due to higher number of secondary amine groups present in TEPA. The amperometric analysis indicated that both the Ag/SBA-15/TAEA and Ag/SBA-15/TEPA modified electrodes required lower over-potential and hence possess high sensitivity towards the detection of $H_2O_2$. The reduction peak currents were linearly related to hydrogen peroxide concentration in the range between $3{\times}10^{-4}\;M$ and $2.5{\times}10^{-3}\;M$ with correlation coefficient of 0.997 and detection limit was $3{\times}10^{-4}\;M$.

• Kyungpook Mathematical Journal
• /
• v.62 no.1
• /
• pp.119-132
• /
• 2022

Virotherapy is an effective method for the treatment of cancer. The oncolytic virus specifically infects the lyse cancer cell without harming normal cells. There is a time delay between the time of interaction of the virus with the tumor cells and the time when the tumor cells become infectious and produce new virus particles. Several types of viruses are used in virotherapy and the delay varies with the type of virus. This delay can play an important role in the success of virotherapy. Our present study is to explore the impact of this delay in cancer virotherapy through a mathematical model based on delay differential equations. The partial success of virotherapy is guarenteed when one gets a stable non-trivial equilibrium with a low level of tumor cells. There exits Hopf-bifurcation by considering the delay as bifurcation parameter. We have estimated the length of delay which preserves the stability of the non-trivial equilibrium point. So when the delay is less than a threshold value, we can predict partial success of virotherapy for suitable sets of parameters. Here numerical simulations are also performed to support the analytical findings.