• Title/Summary/Keyword: Channel Distribution

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Effect of Nifedipine on the Ampicillin Absorption (니페디핀이 암피실린의 흡수에 미치는 영향)

  • Jeong, Hyun-Jeong;Yong, Chul-Soon;Choi, Yoon-Soo;Oh, Doo-Man
    • Journal of Pharmaceutical Investigation
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    • v.27 no.1
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    • pp.57-64
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    • 1997
  • $Amino-{\beta}-lactam$ antibiotics are absorbed by the dipeptide transporter in the small intestine. These uptakes are coupled to a proton influx. The inward proton gradient is partly induced by the $Na^+/H^+$ exchanger and calcium ion is involved in control of this antiport. Interaction between ampicillin which is one of the $Amino-{\beta}-lactam$ antibiotics and nifedipine which is one of calcium channel blocking agents was studied in rats in vivo and with rabbit jejunum mounted on the Sweetana/Grass diffusion cells in vitro. Bioavailability of ampicillin was increased significantly when nifedipine was co-administered orally in rats. There were no differences in the distribution phase and the elimination phase when ampicillin was given either alone or with nifedipine intravenously. Conditions for in vitro experiments were determined. The lift rate of $O_2/CO_2$ gas was controlled to 3 bubbles/sec and ampicillin was stable in the Kreb's buffer at pH 6.0. Absorption of ampicillin was the greatest when the completely-stripped serosal membrane was used. Transport of ampicillin from mucosal to serosal side in the rabbit jejunum was enhanced by 32% in the presence of nifedipine (p=0.059). Above results suggest that nifedipine might increase the plasma level of ampicillin via the improved absorption in the intestine rather than the reduction in the elimination or/and alteration in the distribution.

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Combined Effects of Sideslip and AOA on the Vortical Flow of Delta Wing (삼각날개 와류장에서의 옆미끄럼과 받음각의 복합효과)

  • Lee, Gi Yeong;Son, Myeong Hwan
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.31 no.2
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    • pp.17-24
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    • 2003
  • This paper presents results from steady wind tunnel test conducted on a $65^{\circ}$ delta wing at a root chord Reynolds number of $1.76{\times}10^6$. In these experiments, the wing was instrumented with 188 pressure taps, conjunction with powerful multi-channel data logging system, allowed the wing upper surface pressure distribution to be measured. Analysis indicates that the wing upper surface distribution can provide considerable insight into the comvined aerodynamic effects of angle of attack and sideslip on the wing. In a sideslip condition, the strength of the vortex on the windward side is much stronger than that of leeward side. This asymmetric pressure disstribution betwwen each side of wings result in a negative value of rolling moment. However, at a certatin range of angle of attck and sideslip angle(${\alpha}$=$24^{\circ}{\sim}36^{\circ}C$, ${\beta}$=$-5^{\circ}{\sim}-15^{\circ}C$) abrupt change of sign of rolling monent, rolling monent reversal, was observed.

An analysis of consumer choice between the Internet and TV home shopping channels (인터넷 및 TV 홈쇼핑 채널 간의 소비자 선호 결정 요인)

  • Lee, Gwang-Hoon
    • Journal of Distribution Research
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    • v.12 no.4
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    • pp.27-47
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    • 2007
  • Using survey data and the Heckit model that adequately controls the sample selection bias, we analyze shoppers expenditure through two major emerging shopping channels: Internet shopping and TV home shopping channels. Age, Internet experience, daily Internet usage, the number of computers are factors that affect the ratio of consumers' expenditure through Internet shopping relative to the expenditure through TV home shopping. Shopping frequency which represents the shoppers' incentives to reduce transaction costs also has a positive effect on the proportion of shoppers' expenditure through the Internet shopping. Shoppers' perceptions of convenience, reliability, speed, and diversity are also shown to affect shoppers' relative expenditure ratio through Internet shopping. In contrast, shoppers' perception of prices does not seem to affect their purchasing behavior.

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PIV Applications for Flow Analysis of Floating Breakwater with double barriers (이흘수판형 부소파제 주위의 유동해석을 위한 PIV 적용)

  • Kim, Ho;Cho, Dae-Hwan;Lee, Gyoung-Woo;Gim, Ok-Sok
    • Proceedings of KOSOMES biannual meeting
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    • 2006.11a
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    • pp.53-58
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    • 2006
  • Along with the development of costal engineering, various type of breakwaters have been built. The main purpose of breakwaters are to provide harbour protection against waves, to stabilize beaches against erosion due to large wave action, and to provide for temporary wave protection for installation on or under water surface. This paper an application example of PIV system for analyzing the flow of Floating Breakwater with double barriers. We introduce an analysis method to predict the characteristics of flow around the neighboring fields of Floating Breakwater with double barriers in order to develop a high performance model. Flow visualization has conducted in circulating water channel by a high speed camera and etc. Flowing phenomenon according to velocity distribution and flow separation around the breakwater with double barriers were obtained by 2-D PIV system.

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Design of Security Module using Key Exchange Protocol in Digital Contents (키 교환 프로토콜을 이용한 디지털콘텐츠 보호 모듈 설계)

  • 권도윤;이경원;김정호
    • The Journal of the Korea Contents Association
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    • v.3 no.3
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    • pp.40-46
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    • 2003
  • In the paper, designed digital contents security module to check unlawfulness reproduction and distribution of digital contents. This paper applied Diffie-Hellman algorithm that use discrete logarithm and random number as primary for public key application to create encryption key that agree each other through communication channel between DCPS and HOST, and applied Triple DES repeat DES 3 times through 2 different encryption key that is selecting ANSI X9.17 that is key management standard, ISO 8732 and PEM(Privacy-Enhanced Mail) etc. by secondary protection for safe transmission of digital contents in transmission line. Designed security module consist of key exchange module, key derivation module and copy protection processing module. Digital contents security module that design in this thesis checks reproduction and distribution of digital contents by unauthenticated user through user certification function and digital contents encryption function, and protect digital contents transmission line.

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A Study of the Influence of Roughness on fracture Shear Behaviour and Permeability (거칠기가 절리의 전단거동 및 투수성에 미치는 영향에 관한 연구)

    • Tunnel and Underground Space
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    • v.12 no.4
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    • pp.312-320
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    • 2002
  • It is well-known that when single rock fractures undergo shear displacement, they are influenced by the boundary conditions and fracture roughness. In this case, aperture geometry will change by means of dilation due to the shear displacement. As fractures become the flow paths, fluid flow through rock fractures is affected by the void geometry. In this study, therefore, the influence of roughness on shear behavior of fractures has been investigated, and the resulting hydraulic behavior has been analyzed. In order for this study, a statistical method has been used to generate rough fractures, and they have been adopted into new conceptual models fur fracture shearing and flow calculations. The main contributions of this study are as follows: firstly, fracture shear behavior becomes less brittle with decreasing fracture roughness and increasing normal stress. Then, the characteristics of aperture distribution becomes those of roughness of fractures indicating its hydraulic significance. Finally, it is observed that with decreasing fracture roughness the breakdown of channel flow occurs more slowly.

A Sensitivity Analysis of Model Parameters involved in Clark Method on the Magnitude of Design Flood for urban Watersheds (CLARK 유역추적법에 의한 계획홍수량 산정에 미치는 매개변수의 민감도 분석)

  • Yoon, Kwang-Wonn;Wone, Seog-Yeon;Yoon, Yong-Nam
    • Water for future
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    • v.27 no.4
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    • pp.85-94
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    • 1994
  • A Sensitivity analysis on the model parameters involved in the Clark watershed routing method is made to demonstrate the effect of each parameter on the magnitude of 50-year design flood for small urban streams. As for the rainfall parameter the time distribution pattern of design storm was selected. For short duration storms Huff, Yen & Chow and Japanese Central type distributions were selected and the Mononobe distribution of 24-hour design storm was also selected and tested for Clark method application. The effect of SCS runoff curve number for effective rainfall and the methods of subbasin division for time-area curve were also tested. The routing parameter, i.e. the storage constant(K), was found to be the dominating parameter once design storm is selected. A multiple regression formula for K correlated with the drainage area and main channel slope of the basin is proposed for the use in urban stream practice for the determination of design flood by Clark method.

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Analysis of Thermal Characteristics for Areas of Musim Stream in Cheongju City (청주시 무심천 주변의 열환경 특성 분석)

  • Park, Jin-Ki;Na, Sang-Il;Park, Jong-Hwa
    • Korean Journal of Agricultural Science
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    • v.37 no.1
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    • pp.81-86
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    • 2010
  • The urban thermal environment can be an important index to detect heat island phenomena and manage it to improve urban life quality. Cheongju is a typical plain-city that main part has been formed and developed in lowland. The Mushim stream crosses the city from south to north. We reviewed the use of thermal remote sensing in stream around areas and the thermal environments, focusing primarily on the Urban Heat Island(UHI) effect. The purpose of this study is to determine the relationship between the stream nearby urban area and the stream cooling effect of UHI. The objectives are to determine the usefulness of KOMPSAT-2 bands MS3 and MS4 for vegetation cover mapping, and the usefulness of LANDSAT TM band 6 in identifying thermal environmental characteristics and UHI. Land Surface Temperatures (LST) are retrieved by single-channel algorithm to study the UHI from the 6th band (thermal infrared band) of LANDSAT TM images and thermal radiance thermometer based on remote sensing method and the LST distribution maps are accomplished according to the retrieval results. There is also comparison of satellite-derived and in situ measured temperature. The results indicated that the LST of urban center is higher than that of suburban area, the temperature of mountain and water are the lowest area, so it is clearly proved that there are obvious UHI effects by stream. The surface temperature distribution of Mushim stream is detected $2^{\circ}C$ lower than urban area.

Analysis of Subthreshold Swing for Double Gate MOSFET Using Gaussian Function (가우스함수를 이용한 DGMOSFET의 문턱전압이하 스윙분석)

  • Jung, Hak-Kee;Han, Ji-Hyung;Lee, Jae-Hyung;Jeong, Dong-Soo;Lee, Jong-In;Kwon, Oh-Shin
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.05a
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    • pp.681-684
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    • 2011
  • In this paper, the relationship of potential and charge distribution in channel for double gate(DG) MOSFET has been derived from Poisson's equation using Gaussian function. The subthreshold swing has been investigated according to projected range and standard projected deviation, variables of Gaussian function. The analytical potential distribution model has been derived from Poisson's equation, and subthreshold swing has been obtained from this model. The subthreshold swing has been defined as the derivative of gate voltage to drain current and is theoretically minimum of 60mS/dec, and very important factor in digital application. Those results of this potential model are compared with those of numerical simulation to verify this model. As a result, since potential model presented in this paper is good agreement with numerical model, the subthreshold swings have been analyzed according to the shape of Gaussian function.

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A Study on Flow Zone Development and Bottom Change by Propeller Jets from Ships (선박추진기에 의한 흐름발달과 해저면변화에 대한 연구)

  • 이지훈;이중우
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2002.11a
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    • pp.139-145
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    • 2002
  • The flow zone through propeller jets are used in evaluating the environmental and constructional effects of navigation on the waterway. It relies on the characteristics of ships and water depth. A numerical model using the momentum theory of the propeller and Shield's diagram was developed in a restricted waterway. Equations for discharge are presented based on thrust coefficients and propeller speed and are the most accurate means of defining discharge. Approximate methods for discharge are developed based on applied ship's power. Equations for discharge are as a function of applied power, propeller diameter, and ship speed. Water depth of the waterway and draft of the shop are also necessary for the calculation of the grain size of the initial motion. The velocity distribution of discharge from the propeller was simulated by the Gaussian normal distribution function. The shear velocity and shear stress were from the Sternberg's formula. Case studies to show the influence of significant factors on sediment movement induced by the ship's propeller at the channel bottom are presented.

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