• Journal of Microbiology and Biotechnology
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• v.31 no.1
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• pp.137-143
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• 2021

Most cervical cancers are associated with high-risk human papillomavirus (HPV) infection. Currently, cervical cancer treatment entails surgical removal of the lesion, but treatment of infection and preventing tissue damage are issues that still remain to be addressed. Herbal medicine and biological studies have focused on developing antiviral drugs from natural sources. In this study, we analyzed the potential antiviral effects of Pinus densiflora Sieb. et Zucc. leaf extracts against HPV. The pine needle extracts from each organic solvent were analyzed for antiviral activity. The methylene chloride fraction (PN-MC) showed the highest activity against HPV pseudovirus (PV). The PN-MC extract was more effective before, rather than after treatment, and therefore represents a prophylactic intervention. Mice were pre-treated with PN-MC via genital application or oral administration, followed by a genital or subcutaneous challenge with HPV PV, respectively. The HPV challenge results showed that mice treated via genital application exhibited complete protection against HPV. In conclusion, PN-MC represents a potential topical virucide for HPV infection.

• Journal of Drive and Control
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• v.15 no.4
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• pp.91-100
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• 2018

This study focuses on the energy saving of construction machinery, especially excavators and wheel loaders coming on a backdrop of energy shortage and environment pollution. Due to the problem of the low energy efficiency and the pollution of conventional hydraulic excavators, hybrid hydraulic excavators were developed to solve this challenge. Firstly, this paper discusses the different configurations of the hybrid hydraulic excavator and recent research trend of hybrid hydraulic excavator is reviewed. Secondly, the productions and research of the construction machine companies were analyzed and finally, the future challenges of hybrid technology to the hydraulic excavator were discussed.

• KIISE Transactions on Computing Practices
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• v.23 no.7
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• pp.440-445
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• 2017

Due to the advance of e-commerce systems, the number of people using online shopping and products has significantly increased. Therefore, the need for an accurate recommendation system is becoming increasingly more important. Recurrent neural network is a deep-learning algorithm that utilizes sequential information in training. In this paper, an evaluation is performed on the application of recurrent neural networks to recommendation systems. We evaluated three recurrent algorithms (RNN, LSTM and GRU) and three optimal algorithms(Adagrad, RMSProp and Adam) which are commonly used. In the experiments, we used the TensorFlow open source library produced by Google and e-commerce session data from RecSys Challenge 2015. The results using the optimal hyperparameters found in this study are compared with those of RecSys Challenge 2015 participants.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.1075-1084
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• 2022

The use of Hi-Tech in cultural heritage preservation and the promotion of cultural heritage values in general, particularly artifacts, opens new opportunities for attracting tourists while also posing a challenge due to the need to reward high-quality excursions to visitors historical and cultural values. Building Information Modeling (BIM) and Hi-Tech in new building management have been widely adopted in the construction industry; however, Historic Building Information Modeling (HBIM) is an exciting challenge in 3D modeling and building management. For those reasons, the Scan-to-HBIM approach involves generating an HBIM model for existing buildings from the point cloud data collected by Terrestrial 3D Laser Scanner integrated with Virtual Reality (VR), Augmented Reality (AR), contributes to spatial historic sites simulation for virtual experiences. Therefore, this study aims to (1) generate the application of Virtual Reality, Augmented Reality to Historic Building Information Modeling - based workflows in a case study which is a monument in the city; (2) evaluate the application of these technologies to improve awareness of visitors related to the promotion of historical values by surveying the experience before and after using this application. The findings shed light on the barriers that prevent users from utilizing technologies and problem-solving solutions. According to the survey results, after experiencing virtual tours through applications and video explanations, participant's perception of the case study improved. When combined with emerging Hi-Tech and immersive interactive games, the Historic Building Information Modeling helps increase information transmission to improve visitor awareness and promote heritage values.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.177-179
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• 2022

In the Google Deepmind Challenge match, Alphago defeated Korea's Sedol Lee (human) with 4 wins and 1 loss in the Go match. Finally, artificial intelligence is going beyond the use of human intelligence. The Korean government's budget for the Digital New Deal is 9 trillion won in 2022, and an additional 301 types of data construction projects for artificial intelligence learning will be secured. From 2023, the industrial paradigm will change with the use and application of learning of artificial intelligence in all fields of industry. This paper conducts research to utilize artificial intelligence algorithms. Focusing on the analysis and judgment of data in artificial intelligence learning, research on the appropriate target and scope of application of algorithms in artificial intelligence machine learning and deep learning learning is conducted. This study will provide basic data for artificial intelligence in the 4th industrial revolution technology and artificial intelligence robot use in the 5th industrial revolution technology.

• Proceedings of the Korean Society of Computer Information Conference
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• 2015.01a
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• pp.307-308
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• 2015

The biggest challenge of managing mobile interpretative device is encouraging visitors to have the mobile experience. Thus, in the research of the mobile application of the Leeum, a short orientation session as a treatment was provided to survey participants to make them use of a mobile experience and to solve the problem of hesitancy. Based on the research data, their satisfaction with visiting experience and with using the application appeared to be relatively high. However, several problems such as intrusiveness, isolation, head-down effect and technical problems needed to be improved to have a promising future.

• 한국경영정보학회:학술대회논문집
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• 2007.06a
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• pp.115-119
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• 2007

Huge amount of useful information is getting added to the academic digital world everyday, This digitalized information is heterogeneous and remained limited to a local domain only. How to integrate and share this scattered knowledge with simplicity remained a big challenge. In this paper, we propose a prototype of web application for accomplishing above task using web 2.0 features; it makes traditional academic digital libraries to form as a special case of collaborative environment. This application enables users to customize their own resources to form their own virtual digital library. Further users can utilize personalized information of other users working in similar research domain to form true collaborative environment. The model and framework for the new look of academic digital library is presented.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.12
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• pp.2138-2144
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• 2016

People with visual disabilities suffer environmentally, socially, and technologically. Navigating through places and recognizing objects are already a big challenge for them who require assistance. This study aimed to develop an android-based assistive application for the visually impaired. Specifically, the study aimed to create a system that could aid visually impaired individuals performs significant tasks through object recognition and identifying locations through GPS and Google Maps. In this study, the researchers used an android phone allowing a visually impaired individual to go from one place to another with the aid of the application. Google Maps is integrated to utilize GPS in identifying locations and giving distance directions and the system has a cloud server used for storing pinned locations. Furthermore, Haar-like features were used in object recognition.

• Journal of Microbiology and Biotechnology
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• v.8 no.2
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• pp.101-110
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• 1998

The extent of biological diversity being revealed by molecular techniques accentuates the need to develop methods to isolate and culture the large numbers of microorganisms that remain to be studied. The discovery and characterization of novel microorganisms will provide information useful in understanding microbial ecosystems and have the potential to lead to new products for the biotechnology industry. In this review, the use of innovative techniques and exploration of unusual ecosystems, that have begun to address the challenge of isolating the "uncultured" members of the microbial population, are examined.

• Korean Journal of Veterinary Research
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• v.24 no.2
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• pp.169-171
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• 1984

An expeliment was carried out to measure the cellular immune response in guinea pigs by sensitizing the animals with 2, 4-dinitrochlorobenzene(DNCB). The guinea pigs could be sensitized with one application of DNCB. The sensitizing and challenge dose was standardized. The histological response was characteristic of a delayed hypersensitivity reaction.