• Journal of the Korean Academy of Clinical Electrophysiology
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• v.2 no.3
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• pp.37-49
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• 2004

The purpose of this study was to determine the effect of spinal motor neuron excitability by cranial electrostimulation(CES). The fifteen Sparague-Dawley adult male rats were assigned to the three groups; GroupI(control), GroupII(low rate CES), GroupIII(high rate CES). Spinal motor neuron excitability was measured to use a computerized H reflex. The results of this study was as follows; M latency, M amplitude and H latency were no significant difference in all groups on repeated measured ANOVA(p>.05) but low rate CES and high rate CES groups were lower than ether group in comparative measurement of H amplitude and Hmax/Mmax ratio(p<.05). These results lead to the conclusion that spinal neuron excitability was influenced by CES. These results suggest that CES had the capability to lower spinal motor neuron excitability used synaptic blockade in spinal segment.

• Anxiety and mood
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• v.8 no.2
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• pp.106-112
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• 2012

Objective : In posttraumatic stress disorder (PTSD), it is essential to evaluate the severity of trauma with a reliable instrument. The combat exposure scale (CES) is one of the most widely used measures for the combat-related trauma. The present study was conducted to test the reliability and validity of the Korean version of CES (CES-K). Methods : One hundred and forty-five male Korean veterans of the Vietnam War participated in this study. CES-K, the structured clinical interview for DSM-III-R (SCID), clinician administered PTSD scale (CAPS), and the Korean version life events checklist (LEC-K) were administered. Results : Cronbach's coefficient of CES-K was .85, and the test-retest reliability was .94. The mean [standard deviation (SD)] scores of CES-K were 20.4 (9.0) in the PTSD group and 12.0 (8.6) in the non-PTSD group (p<.001). CES-K showed a significant correlation with LEC-K (r=.31, p<.001) and CAPS (r=.52, p<.001). Only one factor was revealed by the factor analysis. Conclusion : CES-K showed good reliability and validity for assessing the severity of combat exposure. Further, it demonstrated comparable psychometric properties to the previous study. It is expected that CES-K will be a useful tool for evaluating the severity of combat exposure in Korea.

• Journal of the Chungcheong Mathematical Society
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• v.23 no.3
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• pp.425-434
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• 2010

Here we see that the $p-Ces{\grave{a}}ro$ operators, the generalized $Ces{\grave{a}}ro$ operators of order one, the discrete generalized $Ces{\grave{a}}ro$ operators, and their adjoints are all posinormal operators on ${\ell}^2$, but many of these operators are not dominant, not normaloid, and not spectraloid. The question of dominance for $C_k$, the generalized $Ces{\grave{a}}ro$ operators of order one, remains unsettled when ${\frac{1}{2}}{\leq}k<1$, and that points to some general questions regarding terraced matrices. Sufficient conditions are given for a terraced matrix to be normaloid. Necessary conditions are given for terraced matrices to be dominant, spectraloid, and normaloid. A very brief new proof is given of the well-known result that $C_k$ is hyponormal when $k{\geq}1$.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.15 no.1
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• pp.52-56
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• 2012

Congenital esophageal stenosis (CES) can be classified into three types based on the etiology of stenosis: tracheobronchial remnants (TBRs), fibromuscular hypertrophy (FMH), and membranous diaphragm (MD). It is important to make a differential diagnosis because the therapeutic plan for CES is determined by its etiology. Most cases of FMH and MD can be managed with balloon dilatation, whereas cases of TBRs require resection and anastomosis. Thus, the preoperative distinction of TBRs is critical. Recently miniprobe endoscopic ultrasonography (EUS) with a maximum diameter of 2.5 mm has been useful for distinguishing TBRs from FMH in pediatric patients with CES. EUS shows hyperechoic lesions indicating TBR cartilage. Miniprobe EUS is recommended for choosing the correct therapeutic method for CES. We report a case of CES due to TBRs in which a preoperative diagnosis was made in a child using miniprobe EUS without any difficulties.

• Food Science of Animal Resources
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• v.39 no.6
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• pp.918-933
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• 2019

Cacao has been shown to have antioxidant effects and health benefits. However, the applicability of cacao as a meat preservative has not been thoroughly evaluated. Here, we examined the effects of cacao nib extracts (CEs) on suppression of fat oxidation and enhancement of quality characteristics of pork patties. Cacao nib powder was extracted in distilled water or 50%, 70%, or 99% ethanol. CEs prepared using 70% ethanol had the highest total phenolic and total flavonoid contents, and the highest 1,1-diphenyl-2-picrylhytdrazyl radical and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activities. Decompression-concentrated CEs prepared using 70% ethanol and 0.1% ascorbic acid were added to pork patties, and the physiochemical properties of the patties were measured. The pH of all pork patties increased during storage, but tended to decrease according to the CEs content. CEs enhanced the preservation of redness and texture of the pork patties during storage. Analysis of thiobarbituric acid reactive substances (TBARS) in patties revealed that fat oxidation was highly suppressed in all treatment groups containing CEs during storage, and TBARS values decreased according to CE content. Treatment with 0.1% CE reduced fat oxidation to a level similar to that of treatment with 0.1% ascorbic acid. Consumer flavor preference increased according to CE content, and overall preference was the highest for patties prepared with 0.05% and 0.075% CEs. Overall, 70% ethanol was found to be the optimal concentration for extraction of cacao nibs, and adding 0.05% or 0.075% CEs to pork patties yielded the highest quality.

• Steel and Composite Structures
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• v.43 no.6
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• pp.785-796
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• 2022

Concrete-encased steel (CES) beam, in which structural steel is encased in a reinforced concrete (RC) section, is widely applied in high-rise buildings as transfer beams due to its high load-carrying capacity, great stiffness, and good durability. However, these CES beams are prone to shear failure because of the low shear span-to-depth ratio and the heavy load. Due to the high load-carrying capacity and the brittle failure process of the shear failure, the accurate strength prediction of CES beams significantly influences the assessment of structural safety. In current design codes, design formulas for predicting the shear strength of CES beams are based on the so-called "superposition method". This method indicates that the shear strength of CES beams can be obtained by superposing the shear strengths of the RC part and the steel shape. Nevertheless, in some cases, this method yields errors on the unsafe side because the shear strengths of these two parts cannot be achieved simultaneously. This paper clarifies the conditions at which the superposition method does not hold true, and the shear strength of CES beams is investigated using a compatible truss-arch model. Considering the deformation compatibility between the steel shape and the RC part, the method to obtain the shear strength of CES beams is proposed. Finally, the proposed model is compared with other calculation methods from codes AISC 360 (USA, North America), Eurocode 4 (Europe), YB 9082 (China, Asia), JGJ 138 (China, Asia), and AS/NZS 2327 (Australia/New Zealand, Oceania) using the available test data consisting of 45 CES beams. The results indicate that the proposed model can predict the shear strength of CES beams with sufficient accuracy and safety. Without considering the deformation compatibility, the calculation methods from the codes AISC 360, Eurocode 4, YB 9082, JGJ 138, and AS/NZS 2327 lead to excessively conservative or unsafe predictions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.5
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• pp.216-224
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• 2018

The purpose of this study was to measure the depressive symptoms and to determine their relationship with job stress content and social support of manufacturing male workers. A total of 428 male workers were surveyed from July 1 to August 31, 2017 using self-administered questionnaires. For the results, the rate of the depression group was 25.1%. In terms of the CES-D scores by job stress contents, CES-D scores were higher in the high job demand group than in the low group and higher in the low job control group than in the high group. In terms of CES-D scores by social support, CES-D scores were higher in the low supervisor support and coworker support group than in the high group. CES-D scores showed a significant positive correlation with job demand but a negative correlation with job control, supervisor support, and coworker support. In terms of hierarchical multiple regression analysis, higher job demand was associated with lower job control, and lower support of supervisors and coworkers gave high depression scores. Explanatory power for depression score significantly increased by 18.4% according to job demand and added job controls. Explanatory power increased by 14.1% with the support of supervisors and coworkers. The above results suggest that the level of depressive symptoms is highly correlated with job demand, job control, and support of supervisors and coworkers.

• Journal of Microbiology and Biotechnology
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• v.34 no.2
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• pp.249-261
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• 2024

New anti-lung cancer therapies are urgently required to improve clinical outcomes. Since ganodermanontriol (GDNT) has been identified as a potential antineoplastic agent, its role in lung adenocarcinoma (LUAD) is investigated in this study. Concretely, lung cancer cells were treated with GDNT and/or mycophenolate mofetil (MMF), after which MTT assay, flow cytometry and Western blot were conducted. Following bioinformatics analysis, carboxylesterase 2 (CES2) was knocked down and rescue assays were carried out in vitro. Xenograft experiment was performed on mice, followed by drug administration, measurement of tumor growth and determination of CES2, IMPDH1 and IMPDH2 expressions. As a result, the viability of lung cancer cells was reduced by GDNT or MMF. GDNT enhanced the effects of MMF on suppressing viability, promoting apoptosis and inducing cell cycle arrest in lung cancer cells. GDNT up-regulated CES2 level, and strengthened the effects of MMF on down-regulating IMPDH1 and IMPDH2 levels in the cells. IMPDH1 and IMPDH2 were highly expressed in LUAD samples. CES2 was a potential target for GDNT. CES2 knockdown reversed the synergistic effect of GDNT and MMF against lung cancer in vitro. GDNT potentiated the role of MMF in inhibiting tumor growth and expressions of CES2 and IMPDH1/2 in lung cancer in vivo. Collectively, GDNT suppresses the progression of LUAD by activating CES2 to enhance the metabolism of MMF.

• Anxiety and mood
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• v.11 no.1
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• pp.54-60
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• 2015

Objective : To translate Center for Epidemiologic Studies Depression Scale (CES-D) into North Korean language and to examine its reliability and validity Methods : North Korean defectors (n=207) recruited from the call center for North Korean defectors participated. Psychiatrists and psychiatric residents interviewed the participants and made the psychiatric diagnoses. Subsequently, the participants completed the CES-D, Impact of Event-Scale-Revised-North Korea (IES-R-NK), Alcohol Use Disorders Identification Test-North Korea (AUDIT-NK), and Brief Psychological State Inventory for North Korean Refugees (BPSI-NKR) questionnaires. Of the original participants, 143 subjects participated in test-retest reliability study after one week. Results : Cronbach's alpha coefficient of CES-D-NK was superior in both males (0.91) and females (0.93). The test-retest correlation coefficient was high (males, 0.64 ; femals, 0.79). Good convergent validity was evident by significant correlations with IER-R-NK, BPSI-NKR-Depression and BPSI-NKR-PTSD, respectively. CES-D-NK had no or weak correlations with AUDIT-NK and BPSI-NKR-Alcohol, showing its discriminant validity. Conclusion : CES-D-NK could be a reliable and valid tool for screening and assessing depressive symptoms of North Korean defectors.

• East Asian mathematical journal
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• v.34 no.3
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• pp.331-338
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• 2018

We investigate the optimal consumption and portfolio strategies of an agent who has a constant elasticity of substitution (CES) utility function under the negative wealth constraint. We use the martingale method to derive the closed-form solution, and we give some numerical implications.