• 대한전자공학회논문지SD
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• 제43권2호
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• pp.51-59
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• 2006

일반 컴퓨터에서 중앙처리장치와 메모리 사이의 병목현상인 "Von Neumann Bottleneck"을 보이는데 본 논문에서는 이러한 문제점을 해소하고 검색위주의 응용분야에서 우수한 성능을 보이는 Content-addressable memory(CAM) 기반의 확장 가능한 범용 Associative Processor(AP) 구조를 제안하였다. 본 연구에서는 Associative computing을 효율적으로 수행할 수 있는 명령어 세트를 제안하였으며 다양하고 대용량 응용분야에도 적용할 수 있도록 구조를 확장 가능하게 설계함으로써 유연한 구조를 갖는다. 12 가지의 명령어가 정의되었으며 프로그램이 효율적으로 수행될 수 있도록 명령어 셋을 구성하고 연속된 명령어를 하나의 명령어로 구현함으로써 처리시간을 단축하였다. 제안된 프로세서는 bit-serial, word-parallel로 동작하며 대용량 병렬 SIMD 구조를 갖는 32 비트 범용 병렬 프로세서로 동작한다. 포괄적인 검증을 위하여 명령어 단위의 검증 뿐 아니라 최대/최소 검색, 이상/이하 검색, 병렬 덧셈 등의 기본적인 병렬 알고리즘을 검증하였으며 알고리즘은 처리 데이터의 개수와는 무관한 상수의 복잡도 O(k)를 갖으며 데이터의 비트 수만큼의 이터레이션을 갖는다.

• 대한본초학회지
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• 제35권5호
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• pp.33-39
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• 2020

Objectives : Increasing evidence supports the biological and pharmacological activities of essential oils on the central nervous system such as pain, anxiety, attention, arousal, relaxation, sedation and learning and memory. The purpose of present work is to investigate the protective effect and molecular mechanism of cypress essential oil (CEO) against scopolamine (SCO)-induced cognitive impairments in C57BL/6 mice. Methods : A series of behavior tests such as Morris water maze, passive avoidance, and fear conditioning tests were conducted to monitor learning and memory functions. Immunoblotting and RT-PCR were also performed in the hippocampal tissue to determine the underlying mechanism of CEO. Results : SCO induced cognitive impairments as assessed by decreased step-through latency in passive avoidance test, relatively low freezing time in fear conditioning test, and increased time spent to find the hidden platform in Morris water maze test. Conversely, CEO inhalation significantly reversed the SCO-induced cognitive impairments in C57BL/6 mice comparable to control levels. To elucidate the molecular mechanisms of memory enhancing effect of CEO we have examined the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus. CEO effectively elevated the protein as well as mRNA expression of BDNF via activation of cAMP response element binding protein (CREB). Conclusions : Our findings suggest that CEO inhalation effectively restored the SCO-impaired cognitive functions in C56BL/6 mice. This learning and memory enhancing effect of CEO was partly mediated by up-regulation of BDNF via activation of CREB.

• 대한기계학회논문집
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• 제18권4호
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• pp.805-815
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• 1994

The development of automatic production systems has a trend toward Computer Integrated Manufacturing System(CIMS) in recent years. In hardware configuration, CIMS are composed of intelligent CAD/CAM work stations, multifunction CNC machining centers including material handling systems. The DNC systems present the key element of automation hierarchy in a FMS. A DNC system is one which connects a number of numerically-controlled machines to a common memory in a digital computer for part program storage with provision for on-demand distribution of part program data to machines using communication in hierarchical structure of central computer, control computer and cell controller. This paper describes the development of Behind-the-Tape-Reader(BTR) type DNC system using CYBER 180-830 as a central computer and IBM PC-386 cell control computer and NC lathe with FANUC 5T NC controller. In this system, the connection between central computer and cell control computer is done via RS-232C serial interface board, and the connection between cell control computer and FANUC 5T controller is done via parallel interface board. The software consists of two module, central computer communication module for NC program downloading and status uploading, NC machine running module for NC operating.

• Journal of Information Science Theory and Practice
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• 제12권2호
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• pp.64-78
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• 2024

Sentiment analysis is one of the promising approaches for developing a point of interest (POI) recommendation system. It uses natural language processing techniques that deploy expert insights from user-generated content such as reviews and feedback. By applying sentiment polarities (positive, negative, or neutral) associated with each POI, the recommendation system can suggest the most suitable POIs for specific users. The proposed study combines two models for POI recommendation. The first model uses bidirectional long short-term memory (BiLSTM) to predict sentiments and is trained on an election dataset. It is observed that the proposed model outperforms existing models in terms of accuracy (99.52%), precision (99.53%), recall (99.51%), and F1-score (99.52%). Then, this model is used on the Foursquare dataset to predict the class labels. Following this, user and POI embeddings are generated. The next model recommends the top POIs and corresponding coordinates to the user using the LSTM model. Filtered user interest and locations are used to recommend POIs from the Foursquare dataset. The results of our proposed model for the POI recommendation system using sentiment analysis are compared to several state-of-the-art approaches and are found quite affirmative regarding recall (48.5%) and precision (85%). The proposed system can be used for trip advice, group recommendations, and interesting place recommendations to specific users.

• 한국비블리아학회지
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• 제23권2호
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• pp.45-68
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• 2012

기록물은 직간접적으로 기억과 관련되어 있다. 한 사회가 과거를 어떻게 기억하는지는 무엇이 기록관에 수집되고, 그것이 이용자들에게 어떻게 이해되고 이용되는지에 달려있다. 기억은 종종 현시점의 개인적, 사회적 관심에 의해 촉발된다. 따라서 기록물의 해석은 현재의 관심에 따라 달라질 수 있다. 이런 관점에서, 무엇이 이용자들로 하여금 기록물을 찾게 만들고 이용자들이 기록물을 어떻게 이용하는 지의 이용맥락을 안다면, 기록물/기록관이 사회의 기억에 어떤 영향을 미치는지를 알 수 있을 것이다. 웹에서는 이용자들간, 이용자와 기록물/기록관 간의 관계를 쉽게 관찰할 수 있다. 기록관들은웹 2.0 기술 및 디지털 문화를 이용하여 이용자들이 기록물과 어떤 상호작용하는지, 기록에 어떤 기여를 하는지를 관찰함으로써, 사회의 기억을 위한 기록관으로 새로운 자리매김을 할 수 있을 것이다. 본 연구는 기록학이라는 관점에서 기억에 관한 담론을 조명하고, 특히 웹 2.0이라는 새로운 환경에서 어떻게 기록관이 기억을 위한 발판이 될 수 있는지에 대해 논하였다. 이용자와 이용맥락에 중점을 두어 기록학문헌에 비추어진 집단 기억을 논하고, 집단기억이 기록물, 역사, 증거라는 담론과 어떻게 연결되어 설명되어왔는지를 개관하였다. 이러한 이론적 배경을 바탕으로, 웹 2.0 기술이 집단기억을 위해 어떤 기술적인 발판을 제공하는지를 고찰하였다. 또한, 기록물을 둘러싼 포괄적인 내러티브를 만들어가는데 이용자들이 웹 2.0 어플리케이션을 통해 어떻게 자신의 기억을 나누고 집단 기억을 만들어가는지에 관한 사례를 살펴보았다.

• The Korean Journal of Pain
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• 제30권4호
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• pp.258-264
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• 2017

Background: Pulpal pain is one of the most common and severe orofacial pain conditions with considerable adverse effects on physiological processes including learning and memory. Regular exercise is known to be effective on cognitive function as well as pain processing in the central nervous system. Here, the possible effects of regular exercise on pulpal pain response as well as pain-induced changes in learning and memory efficiency in rats were investigated. Methods: Twenty-four male Wistar rats were randomly assigned to the control, capsaicin, exercise, and exercise plus capsaicin groups. Rats in exercise groups were forced to run on a treadmill with a moderate exercise protocol for 4 weeks. Capsaicin was used to induce dental pulp pain. Passive avoidance learning and memory performance was assessed by using a shuttle box apparatus. Results: According to the results, regular exercise could decrease the time course of capsaicin-induced pulpal pain (P < 0.001). Moreover, in capsaicin-treated rats, passive avoidance acquisition was impaired as compared to the control (P < 0.05) and exercise (P < 0.001) groups. Additionally, regular exercise before capsaicin injection could attenuate capsaicin-induced memory impairments (P < 0.05). Conclusions: Taken together, the present data showed that regular exercise has inhibitory effects on capsaicin-induced pulpal pain as well as pain-induced cognitive dysfunction in rats.

• 구강회복응용과학지
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• 제23권2호
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• pp.179-186
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• 2007

The decrease of masticatory function caused by tooth loss leads to a decrease of cerebral blood flow volume resulting in impairment of cognitive function and learning memory disorder. However, the reduced mastication-mediated morphological alteration in the central nervous system (CNS) responsible for senile deficit of cognition, learning and memory has not been well documented. In this study, the effect of the loss of the molar teeth (molarless condition) on the hippocampal expression of glial fibrillary acidic protein (GFAP) protein was studied by immunohistochemical techniques. The results were as follows : 1. The molarless mice showed a lower density of pyramidal cells in the cornu ammonis 1 (CA1) and dentate gyrus (DG) region of the hippocampus than control mice. 2. Immunohistochemical analysis showed that the molarless condition enhanced the time-dependent increase in the cell density and hypertrophy of GFAP immunoreactivity in the CA1 region of the hippocampus. The molarless condition enhanced an time-dependent decrease in the number of neurons in the hippocampal formation and the time-dependent increase in the number and hypertrophy of GFAP-labeled cells in the same region. The data suggest a possible link between reduced mastication and histological changes in hippocampal formation that may be one risk factor for senile impairment of cognitive function and spatial learning memory.

• 혜화의학회지
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• 제12권1호
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• pp.11-26
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• 2003

Alzheimer's disease (AD) is characterized by amyloid deposition and associated loss of neunons in brain regions involved in learning and memory processes. Several causes of evidence support that the congnitive disturbance is closed associated with the deficit of cerebral acetylcholine neurotransmission, and the effect of carboxyl terminal 105 amino acid fragment (CT105) of the amyloid precursor protein (APP) on the gene expression of proinflammatory cytokines. We tested it on the scopolamine-induced amnesia model of the ICR mouse using the Morris water maze with repeated orally administration of 1st Green-Tea extract (200 mg/kg) and 2nd Green-Tea extract (200 mg/kg). The Green-Tea prevents impairment of learning and memory and neuronal loss in mouse models of cognitive disturbance and it demonstrated selectivity for inhibition of acetylcholinesterase (AChE). Furthermore, the repeated administration of Green-Tea, CT105-induced alzheimer's mouse model showed central cholinergic activity by ameliorates learning and memory impairment, and isolation of CD14 microglia showed significantly decreases intracellular release of the proinflammatory cytokines tumor necrosis factor-${\alpha}$, interleukin-$1{\beta}$ and reactive oxygen species (ROS). Because of its composite profile, oral therapeutic index and a prophylactic, Green-Tea is considered the better therapeutic candidate for the treatment of Alzheimer's disease.

• 한국전기전자재료학회논문지
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• 제36권6호
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• pp.547-555
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• 2023

High-density crossbar arrays based on storage class memory (SCM) are ideally suited to handle an exponential increase in data storage and processing as a central hardware unit in the era of AI-based technologies. To achieve this, selector devices are required to be co-integrated with SCM to address the sneak-path current issue that indispensably arises in such crossbar-type architecture. In this perspective, we first summarize the current state of tellurium-based threshold-switching devices and recent advances in the material, processing, and device aspects. We thoroughly review the physicochemical properties of elemental tellurium (Te) and representative binary tellurides, their tailored deposition techniques, and operating mechanisms when implemented in two-terminal threshold switching devices. Lastly, we discuss the promising research direction of Te-based selectors and possible issues that need to be considered in advance.

• Communications for Statistical Applications and Methods
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• 제24권5호
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• pp.481-492
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• 2017

This paper investigates a convergence rate of a test statistics given by two scale sampling method based on $A\ddot{i}t$-Sahalia and Jacod (Annals of Statistics, 37, 184-222, 2009). This statistics tests for longitudinal data having the existence of long memory dependence driven by fractional Brownian motion with Hurst parameter $H{\in}(1/2,\;1)$. We obtain an upper bound in the Kolmogorov distance for normal approximation of this test statistic. As a main tool for our works, the recent results in Nourdin and Peccati (Probability Theory and Related Fields, 145, 75-118, 2009; Annals of Probability, 37, 2231-2261, 2009) will be used. These results are obtained by employing techniques based on the combination between Malliavin calculus and Stein's method for normal approximation.