• Healthcare Informatics Research
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• 제24권4호
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• pp.309-316
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• 2018

Objectives: Both the valence and arousal components of affect are important considerations when managing mental healthcare because they are associated with affective and physiological responses. Research on arousal and valence analysis, which uses images, texts, and physiological signals that employ deep learning, is actively underway; research investigating how to improve the recognition rate is needed. The goal of this research was to design a deep learning framework and model to classify arousal and valence, indicating positive and negative degrees of emotion as high or low. Methods: The proposed arousal and valence classification model to analyze the affective state was tested using data from 40 channels provided by a dataset for emotion analysis using electrocardiography (EEG), physiological, and video signals (the DEAP dataset). Experiments were based on 10 selected featured central and peripheral nervous system data points, using long short-term memory (LSTM) as a deep learning method. Results: The arousal and valence were classified and visualized on a two-dimensional coordinate plane. Profiles were designed depending on the number of hidden layers, nodes, and hyperparameters according to the error rate. The experimental results show an arousal and valence classification model accuracy of 74.65 and 78%, respectively. The proposed model performed better than previous other models. Conclusions: The proposed model appears to be effective in analyzing arousal and valence; specifically, it is expected that affective analysis using physiological signals based on LSTM will be possible without manual feature extraction. In a future study, the classification model will be adopted in mental healthcare management systems.

• Advances in nano research
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• 제15권6호
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• pp.521-531
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• 2023

Quantum-dot cellular automata (QCA) has shown great potential in the nanoscale regime as a replacement for CMOS technology. This work presents a specific approach to static random-access memory (SRAM) cell based on 2:1 multiplexer, 4-bit SRAM array, and 32-bit SRAM array in QCA. By utilizing the proposed SRAM array, a single-layer 16×32-bit SRAM with the read/write capability is presented using an optimized signal distribution network (SDN) crossover technique. In the present study, an extremely-optimized 2:1 multiplexer is proposed, which is used to implement an extremely-optimized SRAM cell. The results of simulation show the superiority of the proposed 2:1 multiplexer and SRAM cell. This study also provides a more efficient and accurate method for calculating QCA costs. The proposed extremely-optimized SRAM cell and SRAM arrays are advantageous in terms of complexity, delay, area, and QCA cost parameters in comparison with previous designs in QCA, CMOS, and FinFET technologies. Moreover, compared to previous designs in QCA and FinFET technologies, the proposed structure saves total energy consisting of overall energy consumption, switching energy dissipation, and leakage energy dissipation. The energy and structural analyses of the proposed scheme are performed in QCAPro and QCADesigner 2.0.3 tools. According to the simulation results and comparison with previous high-quality studies based on QCA and FinFET design approaches, the proposed SRAM reduces the overall energy consumption by 25%, occupies 33% smaller area, and requires 15% fewer cells. Moreover, the QCA cost is reduced by 35% compared to outstanding designs in the literature.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제2권6호
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• pp.383-394
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• 2013

CPU, 메모리 등 모바일 디바이스의 제한된 자원문제를 해결하기 위한 방법으로, 모바일 디바이스의 자원이 아닌 클라우드 서비스 또는 PC등 외부 자원을 사용하는 모바일 클라우드 컴퓨팅(Mobile Cloud Computing, MCC)이 부각되고 있다. 전형적인 MCC 환경(MCC Environment, MCE)은 다른 운영체제 및 플랫폼을 가지는 여러 개의 노드, 모바일 애플리케이션과 서비스들로 구성되어 있고, 중앙관리자는 MCE 전체 품질이 일정 수준 이상을 유지하도록 관리 태스크를 수행한다. 그러나, 노드 수, 모바일 애플리케이션 수, 서비스의 수가 많아지고 서비스 실행빈도가 높아질 경우, 중앙 관리자의 관리 태스크 과중으로 병목현상과 성능저하 문제가 제기될 수 있다. 본 논문에서는 이러한 대규모 MCE의 병목과 성능저하 문제를 해결하고, 전체 품질을 안정화시키기 위한 클러스터링(Clustering) 기반의 최적화 기법을 제안한다. 본 기법을 적용하면 MCE의 전체 품질을 안정화시키기 위한 부하를 최소화하면서, 능동적이며 자율적인 방식으로 품질을 보장할 수 있다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 춘계학술대회
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• pp.308-311
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• 2015

전세계적으로 건강에 대한 관심이 증가되어 기존 의료 장비보다 편리하고 정밀한 비접촉, 실시간 헬스 모니터링 시스템 개발이 요구되고 있다. 그러므로 우리는 UWB(Ultra Wide Band) 레이더를 통해서 인체에 비접촉, 연속적으로 혈관의 운동 신호를 수집하고 이 수집된 데이터를 실시간적으로 신호처리해서 맥박, 수축기 혈압, 이완기 혈압을 측정할 수 있는 임베디드 기반의 전파를 이용한 혈압 모니터링 시스템을 개발하였다. 이 시스템은 임베디드 기반 GUI(Graphic User Interface)의 프로그램을 통해서 UWB 레이더 및 제어 시스템을 모니터링하면서 정확한 정보를 실시간으로 LCD(Liquid Crystal Display)에 표시한다. 임베디드 시스템은 소형화를 위해 제한된 자원을 사용해야 하기 때문에 기존의 PC GUI 설계 모드는 상대적으로 더 큰 메모리를 사용하므로 임베디드 시스템에 적합하지 않을 뿐 만 아니라 더 많은 CPU(Central Processing Unit) 처리시간을 요구한다.

• Journal of Microbiology and Biotechnology
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• 제22권5호
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• pp.708-720
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• 2012

In this study, we assessed the effects of ginsenoside Re (GRe) administration on repeated immobilization stress-induced behavioral alterations using the forced swimming test (FST), the elevated plus maze (EPM), and the active avoidance conditioning test (AAT). Additionally, we examined the effect of GRe on the central adrenergic system by observing changes in neuronal tyrosine hydroxylase (TH) immunoreactivity and brain-derived neurotrophic factor (BDNF) mRNA expression in the rat brain. Male rats received 10, 20, or 50 mg/kg GRe (i.p.) 30 min before daily exposures to repeated immobilization stress (2 h/day) for 10 days. Activation of the hypothalamic-pituitary-adrenal (HPA) axis in response to repeated immobilization was confirmed by measuring serum levels of corticosterone (CORT) and the expression of corticotrophin-releasing factor (CRF) in the hypothalamus. Repeated immobilization stress increased immobility in the FST and reduced open-arm exploration in the EPM test. It also increased the probability of escape failures in the AAT test, indicating a reduced avoidance response. Daily administration of GRe during the repeated immobilization stress period significantly inhibited the stress-induced behavioral deficits in these behavioral tests. Administration of GRe also significantly blocked the increase in TH expression in the locus coeruleus (LC) and the decrease in BDNF mRNA expression in the hippocampus. Taken together, these findings indicate that administration of GRe prior to immobilization stress significantly improved helpless behaviors and cognitive impairment, possibly through modulating the central noradrenergic system in rats. These findings suggest that GRe may be a useful agent for treating complex symptoms of depression, anxiety, and cognitive impairment.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2006년도 한국컴퓨터종합학술대회 논문집 Vol.33 No.1 (D)
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• pp.124-126
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• 2006

Mobile Ad hoc networking is an emerging technology and in these days many applications are being developed to run on these networks. In these networks lookup services are very important because all nodes do not have same resources in term of memory and computing power. Nodes need to use different services offered by different servers. Reliable and efficient scheme should be available for lookup services due to limited bandwidth and low computing power of devices in mobile ad hoc networks. Due to mobility and rapid change in network topology, lookup mechanism used in wired network is not appropriate. Service discovery mechanism can be divided into two main categories Centralized and Distributed. Centralized mechanism is not reliable as there is no central node in these networks. Secondly centralized mechanism leads toward single point failure. We can handle the service discovery mechanism by distributing server's information to each node. But this approach is also not appropriate due to limited bandwidth and rapid change in network. In this paper, we present reliable lookup service scheme which is based on distributed mechanism. We are not using replication approach as well due to low bandwidth of wireless networks. In this scheme service discovery mechanism will be handled through different lookup servers. Reliability is the key feature of our proposed scheme.

• Journal of Korean Neurosurgical Society
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• 제46권6호
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• pp.588-591
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• 2009

Radiologic findings of Bing-Neel syndrome, which is an extremely uncommon complication resulting from malignant lymphocyte infiltration into the central nervous system (CNS) in patients with Waldenstr$\ddot{o}$m's macroglobulinemia (WM), have been infrequently reported due to extreme rarity of the case. A 75-year-old man with WM presented at a neurology clinic with progressive gait and memory disturbances, and dysarthria of 2 months duration. Cerebrospinal fluid and serum protein electrophoresis and immunofixation electrophoresis showed IgM kappa-type monoclonal gammopathy. Brain magnetic resonance imaging revealed multifocal, hyperintense lesions on T2 weighted-images. Brain diffusion-weighted imaging (DWI) demonstrated hyperintensities in cerebral and cerebellar lesions that appeared isointense on apparent diffusion coefficient maps, which were compatible with vasogenic edema. Although histologic analysis is a confirmative study to prove direct cell infiltration into the brain, brain MRI with DWI may be a good supportive study to diagnose Bing-Neel syndrome.

• 한국전산유체공학회지
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• 제17권2호
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• pp.35-41
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• 2012

This paper presents incompressible Navier-Stokes solution algorithm for 2D Free-surface flow problems on the Cartesian mesh, which was implemented to run on Graphics Processing Units(GPU). The INS solver utilizes the variable arrangement on the Cartesian mesh, Finite Volume discretization along Constrained Interpolation Profile-Conservative Semi-Lagrangian(CIP-CSL). Solution procedure of incompressible Navier-Stokes equations for free-surface flow takes considerable amount of computation time and memory space even in modern multi-core computing architecture based on Central Processing Units(CPUs). By the recent development of computer architecture technology, Graphics Processing Unit(GPU)'s scientific computing performance outperforms that of CPU's. This paper focus on the utilization of GPU's high performance computing capability, and presents an efficient solution algorithm for free surface flow simulation. The performance of the GPU implementations with double precision accuracy is compared to that of the CPU code using an representative free-surface flow problem, namely. dam-break problem.

• 대한한의학회지
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• 제21권4호
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• pp.236-241
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• 2000

Background and Purpose : Cerebrovascular accident is a serious neurologic event. It can have temporary or permanent effects on survivors, including memory, cognition and volitional control of voiding. The purpose of this study is to evaluate the clinical effect of moxibustion in patients with voiding dysfunction after a cerebrovascular accident. Methods : Twenty patients with post-stroke voiding dysfunction were studied. All patients had computerized tomography(CT) and magnetic resonance imaging(MRI) to localize the lesion in the central nervous system. They were randomly divided into two groups : the control and moxibustion group. Ten of twenty patients underwent moxibustion treatment by randomization. The moxibustion group receieved moxibustion at three points : Chung-guk (Conception Vessel CV3), Kuanwon (CV4) Kihae (CV6). Residual urine volume evaluation was undertaken in all patients. Results : 1. IIn the balanced bladder time, the moxibustion group had the shorter time than non moxibustion group. But there was no significiant difference between the moxibustion group and non-moxibustion group. 2. In the residual urine volume, the moxibustion group and non-moxibustion group showed a tendency to decrease. But there was no significiant difference between the moxibustion group and non-moxibustion group. Conclusions : Though further study is needed, our findings suggested that the time of achieving balanced voiding was shorter with moxibustion than in the control group.

• 대한임상독성학회지
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• 제4권1호
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• pp.61-64
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• 2006

Glufosinate ammonium (GLA), a phosphinic acid derivate of glutamate, is a broad-spectrum contact herbicide. It structurally resembles glutamate, a typical excitatory amino acid in the central nervous system. In korea, the ingestion of GLA for suicidal attempt or accidental event has increased. The neurological complication of GLA intoxication are characterized by loss of consciousness, convulsion, or memory impairment. But, the exact mechanism of GLA toxicity is yet unknown. This report is about a patient with GLA intoxication who showed anterograde amnesia with selective bilateral hip-pocampal lesions supported GLA intoxication with literature reviews supported.