• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1349-1353
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• 2012

Increasing evidence has revealed that thy-1 was a potential stem cell marker of liver cancer, but no data have been shown on how thy-1 regulates the pathophysiology of liver cancer, such as proliferation, apoptosis, invasion and migration. We previously demonstrated that thy-1 was expressed in about 1% of hepg2 cells, thy-1+hepg2 cells, but not thy-1-, demonstrating high tumorigenesis on inoculation $0.5{\times}10^5$ cells per BACA/LA mouse after 2 months. In the present study, our results showed that higher expression of thy-1 occurs in 72% (36/50 cases) of neoplastic hepatic tissues as compared to 40% (20/50 cases) of control tissues, and the expression of thy-1 is higher in poorly differentiated liver tumors than in the well-differentiated ones. In addition, thy-1 expression was detected in 85% of blood samples from liver cancer patients, but none in normal subjects or patients with cirrhosis or hepatitis. There was a significant negative correlation between thy-1expression and E-cadherin expression (a marker of invasion and migraton), but not between thy-1 expression and AFP expression in all the liver cancer and blood samples. We further investigated the relationship between thy-1 and E-cadherin in liver cancer hepg2 cell line which was transfected with pReceiver-M29/thy-1 eukaryotic expression vector followed by aspirin treatment. Lower expression of E-cadherin but higher expressions of thy-1 were detected in hepg2 cells transfected with pReceiver-M29/thy-1. Taken together, our study suggested that thy-1 probably regulates liver cancer invasion and migration.

• Korean Journal of Medicinal Crop Science
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• v.28 no.3
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• pp.209-220
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• 2020

Background: This study investigated the effects of soil properties on the soil fungal community in first and continuous cultivation areas of Cnidium officinale Makino. Methods and Results: The soil fungal community was analyzed for relative abundance and principal coordinate analysis (PCoA) was conducted using Illumina MiSeq sequencing. The correlation between the soil chemical properties and the soil fungal community was assessed with distance-based linear models (DISTLM). The soil fungal community showed distinct clusters consisting in the continuous cultivation area of C. officinale Makino. PCoA and DISTLM indicated that soil pH, calcium, and available P₂O₅ significantly affected the soil fungal community in the cultivation area of C. officinale Makino. In addition, considering 5 different pathogenic fungi the relative abundance of Fusarium in the continuous cultivation area was significantly higher compared to that in the first cultivation area of C. officinale Makino. Conclusions: This study is important because it has determinined the effects of soil properties on the soil fungal community in both first and continuous cultivation areas of C. officinale Makino. Moreover, these results will be helpful to investigate the cause of continuous cropping obstacle in C. officinale Makino by examining the changes of soil fungal community.

• Journal of Information Display
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• v.4 no.4
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• pp.4-7
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• 2003

The world largest 21.3" LTPS LCD has been successfully developed using SLS crystallization technology. Integration of gate circuit, transmission gate and level shifter was successfully performed in a large area display. Uniform and high performance of high quality grains of SLS technology make it possible to realize a uniform large size LTPS TFT-LCD with half the number of data driver IC's that is typically used in a-Si LCD. High aperture ratio of 65 % was achieved using an organic inter insulating method which lead to a high brightness of 500 cd/$cm^2$.

• Physical Therapy Korea
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• v.11 no.2
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• pp.35-45
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• 2004

The purpose of this study was to investigate the correlation and characteristics between electromyographic (EMG) activities of lower leg muscles and the posturographic assessment of static balance control in normal adults. Twenty-four young, healthy adults(12 males, 12 females) participated in the study. Center of pressure (COP) parameters were obtained using force platform as total path distance, total sway area, X mean frequency and Y mean frequency for 20 seconds in the following conditions: (1) comfortable standing with eyes opened or closed, (2) uncomfortable standing (feet together) with eyes opened or closed, (3) virtual moving surround delivered using Head mount display (HMD) with four different moving patterns. The virtual moving patterns consisted of close-far, superior-inferior tilting (pitch), right-left tilting (roll), and horizontal rotation (yaw) movements. Surface electromyographic activites were recorded on the tibialis anterior, peroneus longus, medial and lateral heads of gastrocnemius muscles under each condition. Correlation between the posturographic measures and EMG activities were evaluated. Total path distance and total sway area of COP were significantly increased during uncomfortable standing. EMG activity of tibialis anterior was significantly more during uncomfortable standing and virtual moving surround stimulation than during comfortable standing. Total path distance and sway area of COP during comfortable standing with closed eyes showed significant positive correlation with the EMG activities of the lateral head of gastrocnemius muscle. Total path distances and total sway area of COP during muscle. Total path distances and total sway area of COP during presentation of virtual moving surround also had significant positive correlations with EMG activities of the lateral head of gastrocnemius muscle under close-far movement.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2011.04a
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• pp.147-152
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• 2011

The purpose of this study is to find out the commercialization cause of 2nd class residential area in urban center as basic research to protect urban residential area against the pressure of commercialization. Through the research that are based on literature, field survey and urban planning map, it analysed the commercialization cause of selected two sites under similar urban condition ; to be a nearby subway station and to be a famous commercial street in site, etc. The consequences of this study are summarized as follows ; First the distance between subway station and residential block and residential commercialization are in inverse proportion each other. Second, the corner lot of a block and the access street directly connected collector street are very important factors to spread commercialization to residential area. Finally, nevertheless first and second results, there is square zone which is very high rate of commercialization within one regardless the distance between subway and residential block. the maximum range of square zone is assumed about 250 meter based on case study.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.345-348
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• 1997

Endoscope image is the shape that a doctor sees inside of patient through endoscope. The characteristics of these images are much effected by the light source of endoscope, specially areas in short distance from a light have much light source and look clear, but areas in long distance from a light look dark relatively because of little light quantity. So we developed a new level adaptive image enhancer for the dark area in a endoscope image. The algorithm we made consists of three parts ; 1) Classification of histogram in segmented area 2) Smoothing and Adaptive Histogram Equalization 3) Adaptive Histogram Modification.

• The korean journal of orthodontics
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• v.44 no.1
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• pp.20-27
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• 2014

Objective: The aims of this study were to evaluate the relationship between the detachment force and bonding resin surface are and to determine the resin bonding surface area that would provide adequate bonding strength with minimum resin volume. Methods: One hundred and sixty human premolars were randomly divided into 4 groups of 40 teeth each. The diameter of the resin surface area in each group was as follows: group 1, 1.5 mm; group 2, 2.5 mm; group 3, 3.5 mm; and group 4, 4.5 mm. Respond Dead Soft straight (length 0.0175 inch) was used to fabricate the retainers, and $Transbond^{TM}$ XT was used to fix the retainers to the tooth surfaces. A pair of teeth was embedded in acrylic blocks for each specimen. Thus, each group comprised 20 samples. Fixed retainers were bonded to the teeth, and vertical force was applied at the middle of wire. The force was measured using a universal testing machine. Results: The mean value of detachment force was the highest for group 4 ($102.38{\pm}2.92N$), followed by group 3 ($63.54{\pm}2.21N$), group 2 ($51.95{\pm}1.61N$), and group 1 ($24.14{\pm}1.38N$). Conclusions: The detachment force of lingual fixed retainers was significantly affected as the area of the resin bonding surface increased. Considering the minimum bonding strength of brackets, a resin bonding surface area with a diameter of 3.5 mm would provide adequate bonding strength.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2011.04a
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• pp.161-166
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• 2011

This research was conducted in order to suggestion management program of Happy house center which facility of detached housings, multi family housing, and semi-detached housing management. This study's purpose is to systematically help create a district customized co-management housing management system among detached housing area by reflecting resident opinion and simultaneously provide basic research. The area of research is Sanjoen district in Ulsan city that compact old detached houses. The research study's results are follows: First, the overall survey results showed that most respondents demanded program of happy house center for housing energy deduction method and support of house insulation cost and heating fuel cost. Second, happy house center try to order of priority or housing maintenance and seek of cost deduction plan. Third, happy house center propose the Maeulmandeulgi(Machizkuri) program or housing management plan for residents' talent contribution.

• Journal of Environmental Science International
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• v.20 no.10
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• pp.1285-1295
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• 2011

In this study, occurrence status of nonpoint pollutants and characteristics of discharge by each nonpoint pollutants were examined through monitoring on nonpoint pollutants caused when raining in vineyard belonging to the agricultural area of various land use patterns. Also, the first flush analysis limited to studies on the existing non-percolation area was applied to percolation area to ascertain availability and criteria of study. Various water quality and sluice of nonpoint pollutants were analyzed, based on which discharge of nonpoint pollutants in agricultural area was ascertained to be influenced greatly by artificial factors such as period, cultivation, management, etc. Meanwhile, the first flush phenomenon at agricultural area was ascertained to occur, and the first flush was quantified through calculation of the first flush ratio. If MFF30 is based, discharge load by each nonpoint pollutants caused when raining was investigated to include 40.8% on the basis of total discharge. In case of SS in pollutants showed the highest first flush phenomenon of 64.8%. Through such a result, calculation possibility of the initial rain criteria was ascertained, and it was determined that reliability-assured criteria were calculated through further monitoring.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.17 no.5
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• pp.43-49
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• 2014

Fairy Pittas use the forest around the valley and Gotjawal as breeding places. This survey was conducted to investigate the characteristic of earthworms, specifically its population density, body size around the breeding site in Gotjawal and the forest around the valley areas from the middle of July to the end of July 2013. A total of 405 individual earthworms were collected in the 100 small established quadrats, in which 315 were found in Gotjawal and 90 were found in the forest around the valley area. The density of earthworms in Gotjawal was significantly higher compared to that forest around the valley area. It was also observed that the body size of earthworms was significantly different between Gotjawal and the forest around the valley area. Proportion of number of individuals which are larger than 7cm in body size was 43%(n=135) in Gotjawal and 84%(n=76) in the forest around the valley area, respectively. Soil area was not important factor to the density of earthworms. We suggest that Gotjawal can be considered as a suitable breeding site for Fairy Pitta because of the richness of its primary food in this area.