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Opuntia dillenii: A Forgotten Plant with Promising Pharmacological Properties

  • Shirazinia, Reza;Rahimi, Vafa Baradaran;Kehkhaie, Ashrafali Rezaie;Sahebkar, Amirhossein;Rakhshandeh, Hassan;Askari, Vahid Reza
    • Journal of Pharmacopuncture
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    • v.22 no.1
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    • pp.16-27
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    • 2019
  • Generative and vegetative parts of the cactuses have had a long-lasting position in folk medicine and their effects could partly be confirmed in scientific experiments. Nowadays, the cactus, fruits, and cladodes are the focus of many studies because of their desirable properties. Therefore, the summarized reports of valuable properties of medicinal plants may be a good way to familiarize researches with a new source of drugs with lower side effects and higher efficacy. Opuntia dillenii, a well-known member of the Cactaceae family, is used as a medicinal plant in various countries and grows in the desert, semi-desert, tropical and sub-tropical areas. It shows diverse pharmacological activities such as: antioxidant, anti-inflammatory, anti-tumor, neuroprotective, hepatoprotective, hypotensive etc. OD fruit also possesses valuable constitutes for instance: betalains, ascorbic acid, total phenol, protein as well as essential elements which suggest the significant potential of this plant as a complementary therapy against several pathological conditions. This review describes experimental evidence about pharmacological and therapeutic potential of OD in order to give the basis of its application in the prevention and treatment of some chronic diseases. More studies on OD can help better understanding of its pharmacological mechanism of action to explain its traditional uses and to identify its potential new therapeutic applications.

A Survey of Operation and Development Direction in KPNFA (KPNFA 운영 및 발전 방향 모색을 위한 설문조사 연구)

  • Lim, Jae-Heon;Na, Eun-Jin;Lee, Moon-Kyu
    • PNF and Movement
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    • v.16 no.3
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    • pp.377-388
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    • 2018
  • Purpose: The purpose of this study was to survey the operation and development direction in KPNFA. Method: The participants of this study consisted of physical therapists who had a KPNFA membership. The satisfaction levels for each item (KPNFA impression, educational programs, and clinical application) were measured using a 5-point Likert scale. The survey was performed during June and July 2018. The total questionnaire was comprised of 648 samples. For the data analysis, descriptive statistics and Spearman correlation analysis were used to compare the general characteristics and all items. Results: In the questionnaire, the impression of KPNFA was 69.21, the instructor specialization in the educational programs was 74.22, and helpful interventions for clinical application scored 74.96. KPNFA's image is competitive; friendly items scored the highest, and operation suitability and communication scored the lowest. The most important factor of the educational program was the quality of the instructors. The most helpful item was the education intervention program. The nervous system was applied to the patient with the highest response. The age of subjects showed a significant positive correlation with KPNFA impression, KPNFA branch impression, and branch problem solving. The work duration of subjects showed a significant negative correlation with instructor specialization. A regular member duration of subjects showed a negative correlation with teaching method, instructor specialization. Conclusions: The KPNFA survey was performed for the first time. In the future, this data will be utilized as the basis for KPNFA policy.

A Study on ODA Budget Allocation by Economic Development Stage and International Norm (경제발전과 국제규범 형성에 기반한 ODA 예산규모에 관한 연구)

  • Chang, Ji-Soon;Jeon, Yongil
    • International Area Studies Review
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    • v.18 no.3
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    • pp.3-21
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    • 2014
  • The OECD DAC has recommended the member countries to raise the ODA budget by 0.7% of GNI. Most of DAC's members, howver, have not reached at the target level, mainly due to global economic crisis, with some exceptions in Northern Europe countries. Korea has increased the ODA budget allocation dramatically, but she could not still meet even the level 0.3%, which is the average level of DAC countries. In terms of national budget operation, DAC country groups are classified as the international norm type and the self-economic dependence type. And then, this study analyzes the time trends of the ODA budget in Korea, comparing with DAC's members on the economic scale. By forecasting Korean ODA budgets by country-type classifications, the optimal size of Korean government's ODA budget is proposed and discussed.

New Approaches for Calibrating Material Factors of Reinforced Concrete Members in Korean Highway Bridge Design Code (Limit State Design) and Reliability Analysis (도로교설계기준(한계상태설계법)의 콘크리트부재 설계를 위한 재료계수 결정법 및 신뢰도 분석)

  • Lee, Hae Sung;Song, Sang Won;Kim, Ji Hyeon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.1
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    • pp.13-24
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    • 2019
  • This paper brings up fallacy of material factors specified for the design of concrete members in the current Korean limit state design code for highway bridges, and proposes new material factors based on a robust optimization scheme to overcome the fallacy. It is shown that the current load factors in the code and the proposed material factors lead to a much higher reliability index than the target index. The load factors are adjusted to yield the target reliability index using the inverse reliability analysis. A reliability-based approach following the basic concept of Eurocode is formulated to determine material factors as well as load factors. The load-material factors obtained by the proposed reliability-based approach yield a lower reliability level than the target index. Drawbacks of the basic concept of Eurocode are discussed. It is pointed out that differences in the uncertainties between materials and members may cause the lower reliability index of concrete member than the target.

Analysis of Donation Demand for Expansion of National Policy Information Collection: Focused on National Association for Policy Information (국가 정책정보 수집력 확대를 위한 기증수요 분석 - 국가정책정보협의회 회원기관을 중심으로 -)

  • Yoon, Hee-Yoon;Oh, Seon-Kyung;Kim, Sin-Young
    • Journal of the Korean Society for Library and Information Science
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    • v.52 no.4
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    • pp.5-26
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    • 2018
  • The National Library of Korea, Sejong is a subject branch of the National Library of Korea, which is centered on policy information for governments and related research institutes. Therefore the strategic orientation of the NLKS to establish the essential identity and to enhance it's capacity is to collect and preserve policy information both domestic and abroad. In order to strengthen the capacity of the NLKS as a national conservation center of policy information, we surveyed and analyzed the perception of the operation and policy information services of the National Association for Policy Information and intention of policy information bulk donations of the member institutions, which are the producers and consumers of policy information. And based on the results, we suggested ways to strengthen the policy collection ability of NLKS.

Evaluating Wind Load and Wind-induced Response of a Twin Building using Proper Orthogonal Decomposition (트윈 빌딩의 적합 직교 분해 기법을 이용한 풍하중 및 풍응답 평가)

  • Kim, Bub-Ryur
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.6
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    • pp.309-314
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    • 2018
  • The wind load and structural characteristics of a twin building are more complex than those of conventional high-rise buildings. The pressure load due to wind on a twin building was therefore measured via wind tunnel experiments to analyze such characteristics. The wind pressure pattern was then deduced from measured data using proper orthogonal decomposition. Channeling and vortex shedding were observed in the first and second modes, respectively. The along-wind loads on the two buildings featured a positive correlation and the cross-wind loads featured no correlation. Such a correlation affected the wind-induced displacement. The structural member connecting the two buildings had an insignificant effect on the positive correlation, but it notably reduced the wind-induced displacement with a negative correlation.

Seismic Fragility Evaluation of Cable Supported Bridges Based on Probability Distribution Using Safety Factors of Structural Members (안전율 확률분포에 근거한 케이블지지교량 주요부재의 내진성능 취약도 평가)

  • Park, Jin-Woo;Kim, Chang-Sung;Kim, Doo-Kie
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.23 no.4
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    • pp.37-44
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    • 2019
  • The purpose of this study is to rationally determine the priority of seismic reinforcement of main(key) members of bridges. Cable Supported bridge was selected as the evaluation target and the reliability based on the probability distribution was used to evaluate the seismic fragility of the key members as a quantitative indicator. The safety factor, which is a random variable, is considered an artificial (fixed load and live load) load and a natural (earthquake, wind, temperature, etc.) load. The seismic load is applied as a possible earthquake during the lifetime of the bridge. From analyzing the fragility of each key member based on the seismic reliability, it can be concluded that the shoe (23.8%) was the most fragile, where the other members are ranked as place concrete (20.5%), pier (18.9%), foundation (17.3%) and cable (5.0%) respectively.

Safety Evaluation of the Precast Half Deck Pannel Joints Reinforced by Connection Rebar (이음철근이 보강된 반단면 프리캐스트 판넬 이음부의 강도 안전성 평가)

  • Hwang, Hoon Hee
    • Journal of the Korean Society of Safety
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    • v.34 no.2
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    • pp.40-47
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    • 2019
  • The Half-depth precast deck is a structural system that utilizes pre-cast panels pre-built at the factory as formwork at the construction stage and as a major structural member at the same time after completion. These systems have joints between segments, and the detail and performance of the joints are factors that have a very large impact on the quality, such as the constructability and durability of the bridge decks. In this study, strength performance evaluation was performed for improved joints using connecting rebar by experimental method. Static loading tests were conducted on the test specimen with improved joint, those with existing joint and those without joint. The test results of the specimens were compared to each other, and the flexural strength required by the design was compared. The flexural strength required in the design was presented by finite element analysis. It has been shown that the flexural strength of the specimens with joints were more than twice that required by the design. But the flexural strength of the specimen with existing joint was about 84% of that without joint. The flexural strength of the specimen with improved joints was a nearly similar degree of that compared to the specimen without joint. And a comparison of the moment-deflection relationship curves of the two specimens also shows a very similar flexural behavior. It is confirmed that improved joint has sufficient flexural strength. In addition to strength, the bridge decks require serviceability, such as deflection and cracking, and in particular, fatigue resistance due to repetitive live loads is an important performance factor. Therefore, further verification studies are required.

Change of teacher knowledge through task design in the teacher-researcher community : Focused on knowledge of students in the area of derivatives application (교사연구공동체에서 과제설계를 통한 교사 지식의 변화 : 도함수 활용 영역에서 학생에 대한 지식을 중심으로)

  • Lee, Kyeong-Hwa;Song, Chang-Geun;Jung, Hye-Yun
    • The Mathematical Education
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    • v.58 no.2
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    • pp.299-317
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    • 2019
  • In this study, we analyzed the change of teacher knowledge through task design in the teacher-researcher community focused on knowledge of students in the area of derivatives application. The following subjects were studied. First, we have analyzed the focus of the discussion related to teacher knowledge of students within the teacher-researcher community. Second, we have analyzed the change of teacher knowledge of students according to the focus. The results of this study are as follows. First, community member' different knowledge of students led the discussion on the task solving paths. The main focus of the discussion was the possibility in inducing responses and motivation. Second, the process of reviewing and evaluating task solving paths and reaching consensus led the improvement of teacher knowledge. Teachers and researchers led changes of teacher knowledge by sharing the knowledge based on previous research and experience, respectively. This ultimately shows the necessity of co-learning between teachers and researchers in teacher education.

Complete Genome Sequencing of Bacillus velezensis WRN014, and Comparison with Genome Sequences of other Bacillus velezensis Strains

  • Wang, Junru;Xing, Juyuan;Lu, Jiangkun;Sun, Yingjiao;Zhao, Juanjuan;Miao, Shaohua;Xiong, Qin;Zhang, Yonggang;Zhang, Guishan
    • Journal of Microbiology and Biotechnology
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    • v.29 no.5
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    • pp.794-808
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    • 2019
  • Bacillus velezensis strain WRN014 was isolated from banana fields in Hainan, China. Bacillus velezensis is an important member of the plant growth-promoting rhizobacteria (PGPR) which can enhance plant growth and control soil-borne disease. The complete genome of Bacillus velezensis WRN014 was sequenced by combining Illumina Hiseq 2500 system and Pacific Biosciences SMRT high-throughput sequencing technologies. Then, the genome of Bacillus velezensis WRN014, together with 45 other completed genome sequences of the Bacillus velezensis strains, were comparatively studied. The genome of Bacillus velezensis WRN014 was 4,063,541bp in length and contained 4,062 coding sequences, 9 genomic islands and 13 gene clusters. The results of comparative genomic analysis provide evidence that (i) The 46 Bacillus velezensis strains formed 2 obviously closely related clades in phylogenetic trees. (ii) The pangenome in this study is open and is increasing with the addition of new sequenced genomes. (iii) Analysis of single nucleotide polymorphisms (SNPs) revealed local diversification of the 46 Bacillus velezensis genomes. Surprisingly, SNPs were not evenly distributed throughout the whole genome. (iv) Analysis of gene clusters revealed that rich gene clusters spread over Bacillus velezensis strains and some gene clusters are conserved in different strains. This study reveals that the strain WRN014 and other Bacillus velezensis strains have potential to be used as PGPR and biopesticide.