• Journal of the Korean Statistical Society
• /
• 제28권4호
• /
• pp.469-478
• /
• 1999

We propose a Kolmogorov-Smirnov-type test for independence of paired failure times in the presence of independent censoring times. This independent censoring mechanism is often assumed in case-control studies. To do this end, we first introduce a process defined as the difference between the bivariate survival function estimator proposed by Wang and Wells (1997) and the product of the product-limit estimators (Kaplan and Meier (1958)) for the marginal survival functions. Then, we derive its asymptotic properties under the null hypothesis of independence. Finally, we assess the performance of the proposed test by simulations, and illustrate the proposed methodology with a dataset for remission times of 21 pairs of leukemia patients taken from Oakes(1982).

• 품질경영학회지
• /
• 제29권3호
• /
• pp.49-65
• /
• 2001

This paper presents new compromise ALT plan which is applied to situations that true relationship between stress and parameters is not known exactly. The assumed failure distribution of this study is one of location-scale family, i. e., exponential, Weibull, and lognormal distributions which have been ones of the popular choices of failure distributions. The method of applying the stress is constant, and the censoring mechanism is Type I censoring. Compared with existing compromise plans under true simple linear model in terms of statistical efficiency, the efficiency of new compromise plan is better than the corresponding other compromise ones in most cases. For case when true model is quadratic, this plan can be used without any severe loss in statistical efficiency. The proposed new compromise ALT plan is illustrated with a numerical example and sensitivity analyses are conducted to study effects of pre-estimates of design parameters.

• Journal of the Korean Statistical Society
• /
• 제28권2호
• /
• pp.195-210
• /
• 1999

We consider a large class of exponential regression models with censored data and propose two modified Fisher scoring methods with corresponding algorithms. These proposed methods improve the Newton-Raphson method in estimating the model parameters. The simulated and real examples are illustrated in aspect of convergence.

• Journal of the Korean Statistical Society
• /
• 제32권1호
• /
• pp.25-32
• /
• 2003

In this paper, we define the mean life process for the right censored data and show the asymptotic equivalence between two kinds of the mean life processes. We use the Kaplan-Meier and Susarla-Van Ryzin estimates as the estimates of survival function for the construction of the mean life processes. Also we show the asymptotic equivalence between two mean residual life processes as an application and finally discuss some difficulties caused by the censoring mechanism.

• Communications for Statistical Applications and Methods
• /
• 제25권2호
• /
• pp.159-172
• /
• 2018

In many epidemiological studies, missing values in the outcome arise due to censoring. Such censoring is what makes survival analysis special and differentiated from other analytical methods. There are many methods that deal with censored data in survival analysis. However, few studies have dealt with missing covariates in survival data. Furthermore, studies dealing with missing covariates are rare when data are clustered. In this paper, we conducted a simulation study to compare results of several missing data methods when data had clustered multi-structured type with missing covariates. In this study, we modeled unknown baseline hazard and frailty with Bayesian B-Spline to obtain more smooth and accurate estimates. We also used prior information to achieve more accurate results. We assumed the missing mechanism as MAR. We compared the performance of five different missing data techniques and compared these results through simulation studies. We also presented results from a Multi-Center study of Korean IBD patients with Crohn's disease(Lee et al., Journal of the Korean Society of Coloproctology, 28, 188-194, 2012).

• Journal of the Korean Data and Information Science Society
• /
• 제25권2호
• /
• pp.327-336
• /
• 2014

재발 사건 자료란 연구대상이 같은 종류의 사건을 반복적으로 경험할 때 발생하는 자료이다. 이러한 재발 사건은 사회과학, 자연과학, 공학, 의약학 등 다양한 분야에서 나타날 수 있다. 재발 사건자료를 분석할 때 연구자의 관심에 따라 사건 발생시간이나 사건 발생간의 소요시간을 이용하여 분석할 수 있다. 이 논문에서는 사건 발생시점간의 소요시간을 이용하여 불완전한 관측을 가진 재발 사건자료를 분석하고자 한다. 이 자료의 특징은 일부 관측대상들이 일정기간 동안 연구에서 제외되는 관측틈을 갖는다는 것이다. 이 때 관측틈은 불완전한 형태로 나타나게 되는데 그 이유는 관측틈의 시작시점은 알고 있지만 종료시점은 알 수 없기 때문이다. 이러한 미지의 종료시점을 추정하기 위해서 구간 중도 절단 방법이 적용된다. 따라서 종료시점이 추정된 후 프레일티를 포함한 회귀모형을 적용하여 공변량이 사건 재발에 미치는 영향을 알아볼 수 있다. 또한 제안한 방법을 실제자료에 적용하여 관측틈을 고려한 경우와 고려하지 않은 경우를 비교하고자 한다.