• Journal of the Korean Society of Manufacturing Process Engineers
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• v.15 no.5
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• pp.86-92
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• 2016

In this study, we used a polymer deposition system, based on fused deposition modeling, to fabricate the 3D scaffold and then fabricated micro-pores on a 3D scaffold using a salt leaching method. Materials included polycaprolactone (PCL) and sodium chloride (NaCl). The 3D porous scaffolds were fabricated according to blending ratio such as PCL (70 wt%)/NaCl (30 wt%) and PCL (50 wt%)/NaCl (50 wt%). The 3D porous scaffolds were observed by scanning electron microscopy. The results showed that 3D porous scaffolds had a deposition width of $500{\mu}m$, contained a pore size of $500{\mu}m$ and below $100{\mu}m$. To evaluate the 3D porous scaffolds for bone tissue engineering, we carried out the cell proliferation experiment using a CCK-8 and a mechanical strength test using a universal testing machine. In summary, the 3D porous scaffold was found to be suitable for cancellous bone of human in accordance with the result of in-vitro cell proliferation and mechanical strength. Thus, a 3D porous scaffold could be a promising approach for effective bone regeneration.

• The Transactions of the Korean Institute of Power Electronics
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• v.13 no.1
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• pp.46-54
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• 2008

In this paper, a low-cost impedance spectroscopy system(LCISS) suitable for modeling the electrochemical power sources such as fuel cells, batteries and supercapacitors is designed and implemented. Since the developed LCISS is composed of simple sensor circuits, commercial data acquisition board and LabVIEW software, a graphic language with powerful HMI(Human-Machine Interface), it is expected ta be widely used in substitution of the expensive EIS instruments. In the proposed system, the digital lock-in amplifier is adopted to achieve the accurate measurements even in the presence of the high level of noises. The developed hardware and software is applied to measure the impedance spectrum of the Ballard Nexa 1.2kW proton exchange membrane fuel cell stack and an equivalent impedance model is proposed based on the measurement results. The validity of the proposed equivalent circuit and the developed system is proven by the measurement of the ac power losses of the PEM fuel celt stack by the ripple current.

• International Journal of Oral Biology
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• v.42 no.2
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• pp.63-70
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• 2017

Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant protein technology, there remains a huge challenge for purifying and using protein antigens rich in hydrophobic domains, such as membrane associated proteins. To overcome current limitations using hydrophobic proteins as vaccine antigens, we adopted in silico analyses which included bioinformatic prediction and sequence-based protein 3D structure modeling, to develop a novel periodontitis subunit vaccine against the outer membrane protein FomA of Fusobacterium nucleatum. To generate an optimal antigen candidate, we predicted hydrophilicity and B cell epitope parameter by querying to web-based databases, and designed a truncated FomA (tFomA) candidate with better solubility and preserved B cell epitopes. The truncated recombinant protein was engineered to expose epitopes on the surface through simulating amino acid sequence-based 3D folding in aqueous environment. The recombinant tFomA was further expressed and purified, and its immunological properties were evaluated. In the mice intranasal vaccination study, tFomA significantly induced antigen-specific IgG and sIgA responses in both systemic and oral-mucosal compartments, respectively. Our results testify that intelligent in silico designing of antigens provide amenable vaccine epitopes from hard-to-manufacture hydrophobic domain rich microbial antigens.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.4
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• pp.284-290
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• 2015

Road traffic noise is closely related with urban forms and urban components, such as population, building, traffic and land-use, etc. Hence, it is possible to minimize the noise exposure problem depending on how to plan new town or urban planning alteration. This paper provides ways to apply for urban planning in consideration of noise exposure through road traffic noise estimation for alteration of small-scale urban form. Spatial autoregressive model from the former study is used as statistical model for noise simulation. The simulation results by the spatial statistical model are compared with those by the engineering program-based modeling for 5 scenarios of small-scale urban form alteration. The error from the limitation of containing informations inside the grid cell and the difficulties of reflecting acoustic phenomena exists. Nevertheless, in the stage of preliminary design, the use of the statistical models that have been estimated well could be useful in time and economically.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.6
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• pp.1021-1029
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• 1992

A rational and straightforward method is introduced for developing continuum models of large platelike periodic lattice structures based on energy equivalence. The procedure for developing continuum plate models involves the use of existing well-defined finite element matrices for the easy calculation of strain and kinetic energies of a repeating cell, from which the reduced stiffness and mass matrices are obtained in terms of continuum degrees- of-freedom defined in this paper. The equivalent continuum plate properties are obtained from the direct comparison of the reduced matrices for continuum plate with those for lattice plate. The advantages of the present continuum method are that it may be applied to arbitrary lattice configurations and may give most diverse equivalent continuum plate properties including all kinds of coupling, while other methods may give only limited structural properties. To evaluate the continuum method developed in this paper, free vibration analyses for both of continuum and lattice plates are conducted. Numerical results show that the present continuum method gives very reliable structural and dynamic properties compared to other well-recognized methods.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.745-745
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• 2002

Both geophysical and geospatial data provide important information in the establishment of the optimal telecommunication systems especially in the mobile telecommunication environment. The objective of this study is to utilize geophysical properties and geospatial information in the analysis of the telecommunication environment through point-to-point wave property modeling. Geophysical properties associated with wave propagation parameters of the earth surface were analyzed based on hierarchical land classification using Landsat ETM＋ and IKONOS images. Three-dimensional geospatial information was obtained by processing stereo aerial images. The results show that the accurate geospatial information and reliable geosphysical property of the surface improve the prediction of receiving power of the receivers located near corners of the buildings where diffractions occur. The wave property model developed from accurate telecommunication environment could be applied to optimal cell planning and delay time analysis.

• Steel and Composite Structures
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• v.39 no.3
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• pp.275-290
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• 2021

The main purpose of this research work is to investigate the critical buckling load of functionally graded (FG) porous plates with graphene platelets (GPLs) reinforcement using generalized differential quadrature (GDQ) method at thermal condition. It is supposed that the GPL nanofillers and the porosity coefficient vary continuously along the plate thickness direction. Generally, the thermal distribution is considered to be nonlinear and the temperature changing continuously through the thickness of the nanocomposite plates according to the power-law distribution. To model closed cell FG porous material reinforced with GPLs, Halpin-Tsai micromechanical modeling in conjunction with Gaussian-Random field scheme are used, through which mechanical properties of the structures can be extracted. Based on the third order shear deformation theory (TSDT) and the Hamilton's principle, the equations of motion are established and solved for various boundary conditions (B.Cs). The fast rate of convergence and accuracy of the method are investigated through the different solved examples and validity of the present study is evaluated by comparing its numerical results with those available in the literature. A special attention is drawn to the role of GPLs weight fraction, GPLs patterns through the thickness, porosity coefficient and distribution of porosity on critical buckling load. Results reveal that the importance of thermal condition on of the critical load of FGP-GPL reinforced nanocomposite plates.

• The Journal of the Korea Contents Association
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• v.18 no.11
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• pp.655-664
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• 2018

Retina transforms the external light into electrical signal that stimulates visual cortex of the brain. Electrical modeling of the retina is useful to understand its structure and action that is a prerequisite to implement the retina as a hardware device. This paper introduces a 2-D electrical network model of vertebrate's retina considering signal pathway of retinal cells and synapses. We implemented a simulator of the retina based on the electrical network model to analyze its operation under various circumstances. Compared to the prior studies, It might contribute designing of artificial retina device in terms of that this study specifically observed input and output reactions of each cell and synapse node under various light intensity on the retina.

• 한국HCI학회:학술대회논문집
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• 2006.02a
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• pp.684-691
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• 2006

As many functionalities such as cameras and MP3 players are converged to mobile phones, more intuitive and interesting interaction methods are essential. In this paper, we present applications and their enabling technologies for gesture interactive cell phones. They employ gesture recognition and real-time shake detection algorithm for supporting motion-based user interface and entertainment applications respectively. The gesture recognition algorithm classifies users' movement into one of predefined gestures by modeling basic components of acceleration signals and their relationships. The recognition performance is further enhanced by discriminating frequently confusing classes with support vector machines. The shake detection algorithm detects in real time the exact motion moment when the phone is shaken significantly by utilizing variance and mean of acceleration signals. The gesture interaction algorithms show reliable performance for commercialization; with 100 novice users, the average recognition rate was 96.9% on 11 gestures (digits 1-9, O, X) and users' movements were detected in real time. We have applied the motion understanding technologies to Samsung cell phones in Korean, American, Chinese and European markets since May 2005.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.4
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• pp.77-85
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• 2009

This paper proposes an efficient system level simulation method for MIMO-OFDM based system in the multi-cell environment. The proposed method analyzes effects of the cell structure, radio channel characteristics and user mobility. The user mobility effect on the system level performance is considered in both channel gain and distance. The receiver SINR calculation procedure is presented in the system which adopts MIMO-OFDM scheme under various system environments. This method can be flexibly extensible to various system environments and provides computationally efficient system level simulation technique which utilizes link level performance analysis. Extensive computer simulations results are presented to obtain the system performance in the various mobile cellular channels using the proposed method. Also this results are analyzed based on the packet error rate for different distances between the base station located in the center of the cell and the mobile user.