• Title/Summary/Keyword: Cell image

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Clear Cell Sarcoma of the Wrist: MRI Findings with Diffusion-Weighted Image and Histopathologic Correlation

  • Chung, Bo Yong;Lee, Seun Ah;Choi, Jung-Ah;Shim, Jung-Weon
    • Investigative Magnetic Resonance Imaging
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    • v.20 no.2
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    • pp.136-139
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    • 2016
  • Clear cell sarcoma is rare and difficult to diagnose. Herein, we present a case of clear cell sarcoma in the dorsum of the wrist with MRI findings, including diffusion-weighted imaging, and histopathologic correlation, which was initially diagnosed as giant cell tumor of tendon sheath.

YOLOv4 Grid Cell Shift Algorithm for Detecting the Vehicle at Parking Lot (노상 주차 차량 탐지를 위한 YOLOv4 그리드 셀 조정 알고리즘)

  • Kim, Jinho
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.18 no.4
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    • pp.31-40
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    • 2022
  • YOLOv4 can be used for detecting parking vehicles in order to check a vehicle in out-door parking space. YOLOv4 has 9 anchor boxes in each of 13x13 grid cells for detecting a bounding box of object. Because anchor boxes are allocated based on each cell, there can be existed small observational error for detecting real objects due to the distance between neighboring cells. In this paper, we proposed YOLOv4 grid cell shift algorithm for improving the out-door parking vehicle detection accuracy. In order to get more chance for trying to object detection by reducing the errors between anchor boxes and real objects, grid cells over image can be shifted to vertical, horizontal or diagonal directions after YOLOv4 basic detection process. The experimental results show that a combined algorithm of a custom trained YOLOv4 and a cell shift algorithm has 96.6% detection accuracy compare to 94.6% of a custom trained YOLOv4 only for out door parking vehicle images.

A New Cell Counting Method to Evaluate Anti-tumor Compound Activity

  • Wang, Xue-Jian;Zhang, Xiu-Rong;Zhang, Lei;Li, Qing-Hua;Wang, Lin;Shi, Li-Hong;Fang, Chun-Yan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3397-3401
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    • 2014
  • Determining cell quantity is a common problem in cytology research and anti-tumor drug development. A simple and low-cost method was developed to determine monolayer and adherent-growth cell quantities. The cell nucleus is located in the cytoplasm, and is independent. Thus, the nucleus cannot make contact even if the cell density is heavy. This phenomenon is the foundation of accurate cell-nucleus recognition. The cell nucleus is easily recognizable in images after fluorescent staining because it is independent. A one-to-one relationship exists between the nucleus and the cell; therefore, this method can be used to determine the quantity of proliferating cells. Results indicated that the activity of the histone deacetylase inhibitor Z1 was effective after this method was used. The nude-mouse xenograft model also revealed the potent anti-tumor activity of Z1. This research presents a new anti-tumor-drug evaluation method.

Immunohistochemical analysis of the effect of low power GaAlAs laser treatment on the expression of proliferating cell nuclear antigen (PCNA) in full-thickness excisional wound of rat skin (CaAlAs 저출력 레이저 자극이 흰쥐의 피부 전층결손 절제 창상의 치유시 proliferating cell nuclear antigen(PCNA)발현에 대한 면역조직화학법적 분석)

  • Kim, Soon-Ja;Koo, Hee-Seo
    • Journal of Korean Physical Therapy Science
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    • v.10 no.1
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    • pp.198-205
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    • 2003
  • We evaluated the effect of low power GaAsAl laser on re-epithelization in full-thickness excisional wound of rat skin. Two full-thickness excisions were made on the back of the experimental animals. Low power laser applications with 10mW intensity were treated experimental animals twice a day for 7 days. On the seventh postoperative day the quantitative analysis of re-epithelization was performed using immunohistochemical staining for proliferating cell nuclear antigen (PCNA). The majority of PCNA immunoreactive cells was observed at epithelial cells in the margin of full thickness excisional wound. The low power laser treatments significantly increased the number of PCNA immunoreactive cell as compared to that of non treated animal group (p<0.01). The shape of PCNA immunoreactive cell appeared as small dark, round to ovoid structures. Most PCNA immunoreactive cells exhibited a high intensity of staining that contrasted sharply with the surrounding background. In conclusion, these findings suggest that GaAlAs laser treatments effectively enhance the epithelial wound healing by the stimulating cell proliferation. Furthermore, the majority of cell proliferation occurred in the margin of full thickness excisional wound.

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Design Concept and Architecture Analysis of Cell Microprocessor (Cell 마이크로프로세서 설계 개념과 아키텍쳐 분석)

  • Moon Sang-Gook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.927-930
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    • 2006
  • While Intel has been increasing its exclusive possession in the system IC semiconductor market, IBM, Sony, and Toshiba founded an alliance to develop the next entertainment multi-core processor, which is named CELL. Cell is designed upon the Power architecture and includes 8 SPE (Synergistic processor Element) cores for data handling, and supports SIMD architecture for optimal execution of multimedia, or game applications. Also, it includes expanded Power microarchitecture. In this paper, we analyzed and researched the Cell microprocessor, which is evaluated as the most powerful processor in this era.

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Optical Resonance-based Three Dimensional Sensing Device and its Signal Processing (광공진 현상을 이용한 입체 영상센서 및 신호처리 기법)

  • Park, Yong-Hwa;You, Jang-Woo;Park, Chang-Young;Yoon, Heesun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2013.10a
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    • pp.763-764
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    • 2013
  • A three-dimensional image capturing device and its signal processing algorithm and apparatus are presented. Three dimensional information is one of emerging differentiators that provides consumers with more realistic and immersive experiences in user interface, game, 3D-virtual reality, and 3D display. It has the depth information of a scene together with conventional color image so that full-information of real life that human eyes experience can be captured, recorded and reproduced. 20 Mega-Hertz-switching high speed image shutter device for 3D image capturing and its application to system prototype are presented[1,2]. For 3D image capturing, the system utilizes Time-of-Flight (TOF) principle by means of 20MHz high-speed micro-optical image modulator, so called 'optical resonator'. The high speed image modulation is obtained using the electro-optic operation of the multi-layer stacked structure having diffractive mirrors and optical resonance cavity which maximizes the magnitude of optical modulation[3,4]. The optical resonator is specially designed and fabricated realizing low resistance-capacitance cell structures having small RC-time constant. The optical shutter is positioned in front of a standard high resolution CMOS image sensor and modulates the IR image reflected from the object to capture a depth image (Figure 1). Suggested novel optical resonator enables capturing of a full HD depth image with depth accuracy of mm-scale, which is the largest depth image resolution among the-state-of-the-arts, which have been limited up to VGA. The 3D camera prototype realizes color/depth concurrent sensing optical architecture to capture 14Mp color and full HD depth images, simultaneously (Figure 2,3). The resulting high definition color/depth image and its capturing device have crucial impact on 3D business eco-system in IT industry especially as 3D image sensing means in the fields of 3D camera, gesture recognition, user interface, and 3D display. This paper presents MEMS-based optical resonator design, fabrication, 3D camera system prototype and signal processing algorithms.

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Graded Noise Elimination and Cluster Boundary Extraction in Confocal Sliced Images (공초점 단층 이미지에서 수준별 잡음제거와 클러스터 경계선 추출)

  • Cho, Mi-Gyung;Kim, Jin-Seok;Shim, Jae-Sool
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.12
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    • pp.2697-2704
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    • 2011
  • In tissue engineering area, researchers observe symbiotic relationship such as proliferation, interaction, division apoptosis with time between cells in process of the 3D cell culture in hydrogels. The 3D cell culture process can be taken photographs into sliced images using confocal microscope. Symbiotic mechanism and changes of cell behaviors can be observed and analyzed from the images acquired by confocal microscope. In this paper, we proposed and developed graded noise elimination method and cluster boundary extraction method to extract boundaries information from sliced confocal images acquired in process of the 3D cell culture in hydrogels. The experiment based algorithm showed excellent performance for eliminating noises that have very small millet-shaped size. It is also showed to extract exact boundaries information for even complex clusters.

Trilinear Isosurface Extraction Using Cell Decomposition (정육면체형 셀의 분해를 이용한 삼중선형 등위면의 계산)

  • Sohn, Bong-Soo
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.2 s.46
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    • pp.83-91
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    • 2007
  • This paper describes an algorithm to compute and visualize a topologically accurate trilinear isosurface from three dimensional volumetric image via cubic cell decomposition. An isosurface is often used for visualizing a three dimensional volumetric image. An isosurface defined in each cubic cell of the volume is triangulated in order to be visualized in a computer. However, most isosurface extraction methods generate a triangulated isosurface which may not be topologically equivalent to the ideal trilinear isosurface. We propose a method to decide a correct connectivity of a trilinear isosurface in a cubic cell and perform appropriate cell decomposition according to the decision. Using the method, we can extract isosurface triangles from the cells generated by the decomposition. We prove that this method generates a triangulated isosurface which is topologically equivalent to the trilinear isosurface. We implemented our proposed algorithm and the result shows it can generate topologically accurate trilinear isosurface.

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Computer-aided Design and Fabrication of Bio-mimetic Scaffold for Tissue Engineering Using the Triply Periodic Minimal Surface (삼중 주기적 최소곡면을 이용한 조직공학을 위한 생체모사 스캐폴드의 컴퓨터응용 설계 및 제작)

  • Yoo, Dong-Jin
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.7
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    • pp.834-850
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    • 2011
  • In this paper, a novel tissue engineering scaffold design method based on triply periodic minimal surface (TPMS) is proposed. After generating the hexahedral elements for a 3D anatomical shape using the distance field algorithm, the unit cell libraries composed of triply periodic minimal surfaces are mapped into the subdivided hexahedral elements using the shape function widely used in the finite element method. In addition, a heterogeneous implicit solid representation method is introduced to design a 3D (Three-dimensional) bio-mimetic scaffold for tissue engineering from a sequence of computed tomography (CT) medical image data. CT image of a human spine bone is used as the case study for designing a 3D bio-mimetic scaffold model from CT image data.