• Journal of Microbiology and Biotechnology
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• 제28권10호
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• pp.1654-1663
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• 2018

Finding a safe and broad-spectrum medication is a goal of scientists, pharmacists, and physicians, but developing and fabricating the right medicine can be challenging. The current study describes the formation of silver nanoparticles (AgNPs) by Fusarium mangiferae. It involves the antibiofilm activity of the nanoparticles against Staphylococcus aureus. It also involves cytotoxic effect against mammalian cell lines. Well-dispersed nanoparticles are formed by F. mangiferae. The sizes of the nanoparticles were found to range from 25 to 52 nm, and UV-Vis scan showed absorption around 416-420 nm. SEM, TEM, and AFM results displayed spherical and oval shapes. Furthermore, the FTIR histogram detected amide I and amide II compounds responsible for the stability of AgNPs in an aqueous solution. AgNPs were observed to decrease the formation of biofilm at 75% (v/v). DNA reducing, smearing, and perhaps fragmentation were noticed after treating the bacterial cells with 50% (v/v). Additionally, cell lysis was detected releasing proteins in the supernatant. It was also observed that the AgNPs have the ability to cause 59% cervical cancer cell line (HeLa) deaths at 25% (v/v), however, they showed about 31% toxicity against rat embryo fibroblast transformed cell lines (REF). The results of this study prove the efficiency of AgNPs as an antibiofilm against S. aureus, suggesting that AgNPs could be an alternative to antibiotics. It must also be emphasized that AgNPs displayed cytotoxic behavior against mammalian cell lines. Further studies are needed for assessing risk in relation to the possible benefit of prescribing AgNPs.

• 대한한방부인과학회지
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• 제23권3호
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• pp.156-172
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• 2010

Purpose: In Oriental medicine, menstruation is a significant index of women's health. Especially high school girls often have various menstrual problems. We think that students who have menstrual problem have some symptoms in relation to an etiological cause. So we had carried out this study to investigate association of DSOM scores and an abnormality of menstruation in oriental medicine. Methods: First we have 2137 high school girls answer to menstrual questionnaire that we made and DSOM, next investigated the pathogenic factor of DSOM which effect dysmenorrhea and menorrhagia using regression model. Logistic regression analysis indicate as follows. Results: 1. In comparison with dysmenorrhea, Qi depression(氣滯), blood stasis(血瘀), dampness (濕), phlegm(痰) is associated positively and liver(肝) negatively. The sensitivity is 64.3%, and the specificity is 75.1%. 2. In comparison with menorrhagia, Blood deficiency(血虛), Qi depression(氣滯), blood stasis(血瘀) is associated positively and liver(肝) negatively. The sensitivity is 53.9%, and the specificity is 76.1%. Conclusion: In this study, that has been carried out to organize the diagnosis of dysmenorrhea and menorrhagia in Oriental medicine, we can see that the disease factors of them were correlated with our Medical theory.

• 한국산학기술학회논문지
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• 제16권1호
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• pp.70-77
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• 2015

한류행사특성이 스폰서십에 미치는 영향 연구를 위해 일본 동경과 나고야소재 공연장에서 한류행사 경험자 199명의 표본을 추출하여 기술통계방법과 다변량통계분석 실시하였다. 연구 변수에 대한 특성을 파악하기 위해 평균, 표준편차 등을 산출하여 항목-전체 상관계수를 측정하였다. 문항 간 내적일관성을 나타내는 크론바하 알파 계수를 이용하여 0.7이상으로 나타나 측정도구에 대한 신뢰도는 양호하였다. 또한 측정도구의 타당성 검증을 위해 탐색적 요인분석을 실시하였으며 요인분석 결과 측정도구에 대한 타당성은 확보되었다. 가설인 한류행사특성이 스폰서십에 유의한 영향 관계를 보이는가를 알아 보기 위해 대 가설 1개를 중심으로 소 가설을 4개로 설정하고 분석하여 3개 채택, 1개 기각되는 결과를 도출하였다. 결과적으로는 설정한 대가설은 유의한 영향요소가 있음으로 채택하였다. 하지만 선행연구가 부족한 분야에 뜻하지 않게 상의한 결과에 대해서는 후속연구가 활발히 이루어져 본 연구 분야의 이론적 체계화는 물론 현업에서도 성과가 도출되기를 기대한다.

• Journal of information and communication convergence engineering
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• 제8권6호
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• pp.645-650
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• 2010

In this paper, we present the effect of binocular cues which plays crucial role for the visualization of a stereoscopic or 3D image. This study is useful in extracting depth and disparity information by image processing technique. A linear relation between the object distance and the image distance is presented to discuss the cause of cybersickness. In the experimental results, three dimensional view of the depth map between the 2D images is shown. A median filter is used to reduce the noises available in the disparity map image. After the median filter, two filter algorithms such as 'Gabor' filter and 'Canny' filter are tested for disparity visualization between two images. The 'Gabor' filter is to estimate the disparity by texture extraction and discrimination methods of the two images, and the 'Canny' filter is used to visualize the disparity by edge detection of the two color images obtained from stereoscopic cameras. The 'Canny' filter is better choice for estimating the disparity rather than the 'Gabor' filter because the 'Canny' filter is much more efficient than 'Gabor' filter in terms of detecting the edges. 'Canny' filter changes the color images directly into color edges without converting them into the grayscale. As a result, more clear edges of the stereo images as compared to the edge detection by 'Gabor' filter can be obtained. Since the main goal of the research is to estimate the horizontal disparity of all possible regions or edges of the images, thus the 'Canny' filter is proposed for decipherable visualization of the disparity.

• 만화애니메이션 연구
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• 통권36호
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• pp.1-17
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• 2014

이 연구는 형식적인 측면으로 쇼트에서의 아이러니적 반전과 내용적인 측면으로 내러티브 구조 안에서 복선으로 인한 아이러니를 살펴보고자 하였다. 미국의 주요 애니메이션 제작사인 PDI Dreamworks, Pixar에서 만들어진 최근 장편 애니메이션에서 아이러니가 어떻게 사용되었는지 고찰해보고자 하였다. 표현된 것과 숨겨진 실제 간의 괴리인 아이러니는 본 연구에서 살펴본 바와 같이 두 가지로 정리된다. 아이러니는 상황설정 후 예상과 암시의 과정을 거쳐 마지막 장면에서 극적으로 나타난다. 주로 극중에 등장하는 캐릭터의 성격묘사나 사건이 일어날 배경의 설정을 위해 사용되어 웃음을 전해준다. 두 번째로 아이러니와 관련하여 애니메이션 초반에 등장한 복선이 극의 중반 또는 후반에 인과관계를 가지고 반전으로 드러났다. 이 아이러니는 극적인 요소를 강화시키며 이야기를 풍성하게 만들어주기 위해 사용되었다. 미국의 주요 제작사에서 제작된 두 편의 장편 애니메이션에서 분석해본 결과, 연속되는 장면에서의 아이러니나 내러티브 안에서 연속되는 등의 다양한 아이러니적 표현의 사용을 찾아볼 수 있었다.

• 대한소아치과학회지
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• 제30권1호
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• pp.80-91
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• 2003

치아우식증의 원인균인 S. mutans GS5와 S. sobrinus 6715에 대한 polyP의 효과를 관찰하여 보다 안전하고 효과적인 치아우식증 예방을 위한 임상적용의 가능성을 고찰하고자 첫째, 다양한 사슬길이의 polyP를 첨가한 후 흡광도를 측정하여 MIC를 결정하고, 둘째, 실험균주를 흡광도 $0.3{\sim}0.5$까지 증식시킨 후 MIC 농도의 polyP를 첨가하여 흡광도의 변화를 측정함으로써 균주증식 후 성장 억제효과를 관찰하였으며, 셋째, 생균수 측정으로 polyP의 항균효과를 평가하였고, 넷째, 핵산유리의 정도로 polyP의 킬레이션 작용여부를 관찰하였으며, 다섯째, polyP의 비수용성 글루칸 합성능력을 관찰하였으며, 여섯째, 투과전자현미경으로 세포막과 세포질 내의 구조적 변화를 관찰하였다. 이상의 연구를 통하여, polyP의 살균작용이 S. mutans와 S. sobrinus에 대한 성장을 억제시키는 효과가 있는 것으로 가늠된다. 이와 같은 성장 억제효과는 polyP의 킬레이션에 의한 것이라기보다는 균주 세포의 구조적, 형태적 변화가 주된 요인이었던 것으로 판단된다.

• 한국환경보건학회지
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• 제38권5호
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• pp.398-406
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• 2012

Objectives: In order to investigate the relation between environmental pollution and its effect on human health in large-scale industrial complex regions, monitoring studies have been conducted since 2003. The main purpose of this Gangneung study is to produce background data which can be compared with several large-scale industrial complex regions such as Ulsan, Sihwa, Banwol, Gwangyang, Yeosu, Pohang and Cheongju Daesan industrial complexes. Methods: In this Gangneung study, 1,007 local residents were recruited and the framework of this study was designed to evaluate and monitor health effects associated with low-level but long-term exposure to environmental pollutants. A survey was performed based on personal questionnaires, medical check-ups, and allergy skin prick tests for twelve common allergens. The authors reviewed the prevalence rate of skin allergens in Gangneung compared with in large-scale industrial areas. The results are summarized as follows. Results: The diagnosis prevalence and medical treatment prevalence of asthma were lower than in industrial complex regions, but allergic rhinitis was higher. The allergy skin test prevalence was 26.0% and the most common allergens were dust mites (D. pteronysinus 16.7% and D. farinae 16.3%). Conclusions: The positive findings of the skin prick test were similar with large-scale industrial complex regions in Korea. Further study is required to find the cause of the regional differences in skin prick prevalence.

• 한국학교보건학회지
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• 제15권1호
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• pp.49-62
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• 2002

This study was intended to examine the pattern and level of experience of voice problems and risk factors in school teacher, to offer basic data to prevent voice problems. The subjects were 180 school teachers from primary, middle, and high school teachers in C City, Chonbuk. Data were collected by questionnaires survey from April 30, 2001 to May 10, 2001. 56.6% of the subjects experienced voice problems such as "H-notes difficult"($2.68{\pm}.86$), followed by "Tired voice"($2.32{\pm}.93$), "Effortful voice"($2.27{\pm}.90$), and "Drying of throat"($2.21{\pm}.91$). According to general characteristics, smoking subjects showed higher voice problem than no smoking subjects and this difference was statistically significant(t=2.76, p=.007). According to voice related characteristics, "Speaking loudly" subjects showed higher voice problem than those no "Speaking loudly"(t=-2.02, p=.045). "Speaking effortful" subjects measured higher voice problem than those of "Speaking effortful" and this difference was statistically significant(t=-3.34, p=.001). The inspection of the relation of cause affecting school teachers showed that it had an interacting effect of voice habit, smoking, experienced voice problem, treatment(due to voice problem) experience, by staged it accounted for 55.3% of the total voice problem. The total voice problem indicated a positive correlation(p=.000). Conclusion: over half of the school teachers have experienced voice problems, higher perceived related of voice symptom and physical symptom factors. Also, because there are significant differences in voice problem according to smoking, voice habits of "Speaking loudly", "Speaking effortful", experienced voice problem, treatment(due to voice problem) experience.

• 디자인학연구
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• 제15권4호
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• pp.149-156
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• 2002

제품성공은 제품에 대한 소비자선호를 바탕으로 해서만 가능하며 제품에 대한 소비자선호는 그 디자인에 의해 가장 큰 영향을 받는다. 디자이너는 소비자선호에 대해 이해하고 그 선호를 특정 디자인요소들의 조합으로 전환하여 그들이 원하는 이미지의 제품을 디자인해야만 제품을 성공시킬 수 있다. 즉, 디자인 측면에서는 소비자선호구조 즉, 디자인선호도-디자인 이미지-디자인요소와의 관계를 명확하게 규명할 필요가 있다. 본 연구에서는 기존 연구들이 간과했던 소비와 디자인간의 상호관계를 확인할 수 있도록 디자인 선호도-디자인 이미지-디자인 요소들간의 명확한 인과관계를 규명하여 디자인 계획시 체계적인 지침을 제공하고자 한다. 이를 위해 디자인에 대한 소비자반응 프레임웍인 선호정도-이미지-디자인 요소들간의 명확한 인과관계를 규명할 수 있는 실마리를 제공하는 Bloch(1995)의 제품디자인에 대한 소비자반응이론을 고찰하여 연구모델을 구축하고 실증분석을 통해 디자인 선호도-디자인 이미지-디자인 요소들간의 관계를 분석하여 디자인할 수 있는 방법을 제공한다.

• 대한물리치료과학회지
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• 제30권3호
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• pp.23-30
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• 2023

Background: Flexion of cervical and lumbar joints is required when viewing a smartphone screen. Thus, these joints are overused, together with the surrounding joints and muscles. Long-term use of smartphones will cause changes in cervical and lumbar posture. The effect on forward head posture will vary, depending on the angle of cervical flexion start position in relation to the smartphone. This study investigated how forward head posture changes over time when using a smartphone at 20° and 40° cervical flexion start positions. Design: Cross-sectional study. Methods: Twenty-five subjects with a forward head posture angle of 35° or less participated in the study. A Forward Head Posture app on the participants' smartphones measured forward head posture 5 and 10 minutes after watching videos on their smartphones. Cervical range of motion was used to set a smartphone watching start posture of 20° and 40° of cervical flexion. Results: There was no significant difference in forward head posture, irrespective of cervical flexion start position, but the angle of forward head posture increased more at cervical flexion of 40° than at cervical flexion of 20°. There was no significant difference in what according to smartphone video viewing times, but the angle of forward head posture increased over time. Conclusion: An increase in forward head posture over time with smartphone usage poses a potential risk of neck and shoulder pain. Therefore, smartphone users should avoid prolonged screen time.