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Voiding cystourethrography in children with an initial episode of febrile urinary tract infection (생후 처음으로 발생한 발열성 요로감염 환자의 배뇨성 방광 요도 조영술)

  • Lee, Hae Jeong;Lee, Won Deok;Kim, Hyun Seok;Kim, Tae Hong;Lee, Joo Seok;Cho, Kyung Lae
    • Clinical and Experimental Pediatrics
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    • v.49 no.6
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    • pp.653-658
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    • 2006
  • Purpose : Because voiding cystourethrography(VCUG) is an invasive method, we studied whether VCUG could be postponed through evaluation of alternative non-invasive tests including renal ultrasonography and $^{99m}Tc$-DMSA renal scan. Methods : We reviewed the medical records of 175 patients initially diagnosed with febrile urinary tract infection during the one year period of 1999, and compared 3-tests : renal ultrasongraphy, $^{99m}Tc$-DMSA renal scan, and VCUG. Results : Renal ultrasonography didn't contribute to the prognostication of pyelonephritis(photopenic areas) or vesicoureteral reflux(VUR). Presentation of photopenic areas in $^{99m}Tc$-DMSA renal scan was related to VUR. If both findings of renal ultrasonography and $^{99m}Tc$-DMSA renal scans were normal, this condition was closely related to normal results in VCUG. And if both examinations were abnormal, the condition was closely related to VUR. But this state could not always guarantee the normal result from VCUG because of low sensitivity in finding VUR. Conclusion : In cases in which acute phyelonephritis is demonstrated by $^{99m}Tc$-DMSA renal scan, VCUG is required. In addition to this, if the conditions of hydronephrosis, vesicoureteral dilatation, increases of renal volume, and changes of echogenesity are shown by renal ultrasonography, VCUG should be performed. If a patient has difficulty undergoing VCUG, temporary postponement of VCUG can be taken into consideration, but only in cases where both examinations of renal ultrasonography and $^{99m}Tc$-DMSA renal scan are normal. Nevertheless, close observation is be advised even in this case.

Neuroprotective effects of resveratrol via anti-apoptosis on hypoxic-ischemic brain injury in neonatal rats (신생 백서의 저 산소 허혈 뇌손상에서 항세포사멸사를 통한 resveratrol의 신경보호 효과)

  • Shin, Jin Young;Seo, Min Ae;Choi, Eun Jin;Kim, Jin Kyung;Seo, Eok Su;Lee, Jun Hwa;Chung, Hai Lee;Kim, Woo Taek
    • Clinical and Experimental Pediatrics
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    • v.51 no.10
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    • pp.1102-1111
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    • 2008
  • Purpose : Resveratrol, extracted from red wine and grapes, has an anti-cancer effect, an antiinflammatory effect, and an antioxidative effect mainly in heart disease and also has neuroprotective effects in the adult animal model. No studies for neuroprotective effects during the neonatal periods have been reported. Therefore, we studied the neuroprotective effect of resveratrol on hypoxic-ischemic brain damage in neonatal rats via anti-apoptosis. Methods : Embryonic cortical neuronal cell culture of rat brain was performed using pregnant Sprague-Dawley (SD) rats at 18 days of gestation (E18) for the in vitro approach. We injured the cells with hypoxia and administered resveratrol (1, 10, and $30{\mu}g/mL$) to the cells at 30 minutes before hypoxic insults. In addition, unilateral carotid artery ligation with hypoxia was induced in 7-day-old neonatal rats for the in vivo approach. We injected resveratrol (30 mg/kg) intraperitoneally into animal models. Real-time PCR and Western blotting were performed to identify the neuroprotective effects of resveratrol through anti-apoptosis. Results : In the in vitro approach of hypoxia, the expression of Bax, caspase-3, and the ratio of Bax/Bcl-2, indicators of the level of apoptosis, were significantly increased in the hypoxia group compared to the normoxia group. In the case of the resveratrol-treated group, expression was significantly decreased compared to the hypoxia group. And the results in the in vivo approach were the same as in the in vitro approach. Conclusion : The present study demonstrates that resveratrol plays neuroprotective role in hypoxic-ischemic brain damage during neonatal periods through the mechanism of anti-apoptosis.

Determination of Equivalent Hydraulic Conductivity of Rock Mass Using Three-Dimensional Discontinuity Network (삼차원 불연속면 연결망을 이용한 암반의 등가수리전도도 결정에 대한 연구)

  • 방상혁;전석원;최종근
    • Tunnel and Underground Space
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    • v.13 no.1
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    • pp.52-63
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    • 2003
  • Discontinuities such as faults, fractures and joints in rock mass play the dominant role in the mechanical and hydraulic properties of the rock mass. The key factors that influence on the flow of groundwater are hydraulic and geometric characteristics of discontinuities and their connectivity. In this study, a program that analyzes groundwater flow in the 3D discontinuity network was developed on the assumption that the discontinuity characteristics such as density, trace length, orientation and aperture have particular distribution functions. This program generates discontinuities in a three-dimensional space and analyzes their connectivity and groundwater flow. Due to the limited computing capacity In this study, REV was not exactly determined, but it was inferred to be greater than 25$\times$25$\times$25 ㎥. By calculating the extent of aperture that influences on the groundwater flow, it was found that the discontinuities with the aperture smaller than 30% of the mean aperture had little influence on the groundwater flow. In addition, there was little difference in the equivalent hydraulic conductivity for the the two cases when considering and not considering the boundary effect. It was because the groundwater flow was mostly influenced by the discontinuities with large aperture. Among the parameters considered in this study, the length, aperture, and orientation of discontinuities had the greatest influence on the equivalent hydraulic conductivity of rock mass in their order. In case of existence of a fault in rock mass, elements of the equivalent hydraulic conductivity tensor parallel to the fault fairly increased in their magnitude but those perpendicular to the fault were increased in a very small amount at the first stage and then converged.

A Study of the Improvement of Clinical and Practical Trainings in the Education of Radiologic Technologists (방사선사(放射線士) 교육(敎育)의 임상실습(臨床實習) 개선(改善)에 관(關)한 연구(硏究))

  • Lee, Man-Koo;Kang, Se-Sik;Yoon, Han-Sik;Huh, Joon
    • Journal of radiological science and technology
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    • v.6 no.1
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    • pp.117-129
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    • 1983
  • This study, in order to improve clinical and practical trainings in the education of radiologic technologists, applies to 76 medical institutions of 91 ones which are used as the hospitals of clinical and practical training in 9 existing junior colleges except 3 new ones of 12 ones throughout all over the country from November 1, in 1982 to April 30, in 1983. And the purpose of this study is to research the percent conditions of basic practical trainings and clinical ones enforced in each college, and the percent conditions, equipments, contents, and opinions in clinical and practical trainings enforced in each hospital. The results are summarized as follows; 1. In the case of junior colleges in the whole country the curriculum of basic practical trainings averages 336.66 hours and the limits are between 120 and 510 hours. The actual hours in practice average 140 hours and the limits are between 60 and 240 hours, which correspond to 41.58% of the curriculum of basic practical trainings. 2. There were three junior colleges among nine that had a reserved hospital for clinical and practical trainings(only 33.33%). 3. The period of the practice was almost vacation in 4 junior colleges. The practice was conducted only for students to want the practice(44.45%), junior colleges that all students in them conducted the practice was 2 junior colleges and presented 22.22%. 4. In the field of students engaging in the practice, each field of radiation therapy and nuclear medicine presented 16.5%, 20.3% and almost students didin't have experience for the practice. 5. In medical institutions the educational institutions for intern showed 67.11%. Hospital with radiologist showed 26.32%. Radiotechnologist who had experience below 5 years presented 60.17%. 6. In the equipment for radiation diagnosis, each hospital had no difference. The number of hospitals passessing diagnostic equipments above 125 KVP was 56.26%. But radiation therapy equipment and nuclear medicine equipment had extremely low rate. 7. In the diagnosis of patient in the practice hospital, conventional radiography-to Skull, Chest, Abdomen, Skeleton, Urogenital system-reached the criterion. But special radiography was comparatively low. There appeared low rate, 32.89% in the field of nuclear medicine, 15.79% in the field of radiation therapy. 8. Students who carried out the practice were 1-89 students, days in practice were 1-30 days. There were differences in that point among among hospitals. Junior colleges conducting the practice were 2 colleges per hospital. Scope of the object were 1-8 junior colleges. 9. The practice conducted for the request of the colleges presented 72.37%, in addition, The prctices were conducted for growth of the younger generation and the same coperation with the colleges establishment of sisterhood with the colleges, relationship with students. 10. The practice conducted without the establishment of plan presented 59.21% The need for guiding book to the practice and evaluating was recognized over 90%. 11. In the relation between the practice with achievement of credit. There were big differences in opinion between hospitals-Group and the colleges-Group; hospital-Group had opinion that must follow achievement of credit with the practice. The colleges-Group had opinion that must conduct the practice after achieving credit. 12. After conducting the practice, in the practice leaders satisfaction degree dissatisfactory opinion presented the most rate 80.26%. Very much satisfactory opinion, as one hospital, presentd only 1.32%. 13. Both hospitals-Group and the colleges-Group had an opinion that the practice leader must have actual experiences, lectures and achievement, an opinion that actual experiences is over 5 years. 14. In the guide of human relation, cooperation, responsibility, courtesy to patients. Both hospitals-Group and the colleges-Group had an opinion that the guide must be involved in the period of the practice and must be instructed.

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A Study on Purchasing Decision Making and Adoption : Focused on the RFID Purchasing Customer (구매의사 결정과 수용에 대한 연구 : RFID 구매고객 중심으로)

  • Seo, Pil-Su;Jang, Jang-Yi;Shim, Kyeng-Su
    • 한국벤처창업학회:학술대회논문집
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    • 2008.11a
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    • pp.257-282
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    • 2008
  • RFID (Radio Frequency Identification) is regarded as a core technology of ubiquitous computing. Although it has some technical limitations such as technological standardization of RFID tags as well as economical limitations, many companies around the world have already accepted RFID to improve their management efficiency. In this regard, this study is to meet with results that the adoption of RFID technology willbring opportunities that companies' operational process are improved and customer satisfaction is highly strengthened. This research focuses on providing more understanding for building RFID marketing strategy to suppliers who want to sell their RFID products to customers through analyzing purchasing process. The findings are as follows; First, the study shows that buying center members usually take product reliability and precision of technical specification in the case of new-task buying situation while they put their first purchasing priority on prices in the straight rebuy. Second, the finding presents that in new-task buying situation and the straight rebuy purchasing personnel get information about new products through product performance test, organizational engineers, opinions from other companies' purchasing personnel, and checking out samples. Third, this research demonstrates when it comes to purchasing risk in their first purchasing, the persons who are in charge of material purchasing are inclined to be aware of the risk most in technical problems, followed by financial problems and time delay problems in order. And in addition to those risks are mentioned above, once-again-purchasers take the risk like an opportunity loss for better products into consideration. Fourth, the study shows that the role of concerning departments makes no difference in each purchasing stage. Accordingly marketers need to beef up the differentiated strategy to persuade their customers. Fifth, the findings of this study demonstrate that purchasing decision making is much influenced by the final users. So suppliers are supposed to perform the most active marketing strategy at the first stage of purchasing through various resources. Finally, the study presents that the suppliers who will have had close relationships with their customers need to give consistent information to them so that their customers can have lower motive in purchasing products from competitors.

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A Study on the Influence of Youth Startup Support Project in Gangwon-do Province on Startup Performance (강원도 청년창업 지원사업이 창업성과에 미치는 영향에 관한 연구)

  • Yun, Jiwon;Park, Woojin;Bae, Byung Yun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.4
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    • pp.135-149
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    • 2020
  • As youth employment has become a social issue every year, the government is pushing for policies to support youth start-ups to create jobs voluntarily as a way to enhance the youth employment rate. In the case of young people in Gangwon Province, the number of people moving to other regions is increasing. This research is intended to empirically analyze the actual achievements of youth start-ups through the 'Youth Start-up Project' in Gangwon-do. It was divided into four categories: participation in government support, education completion, intellectual property right retention, and certification retention, which are characteristics of start-up companies, and hypotheses that they will have a positive impact on start-up performance (sales amount, duration of existence, or whether they are retained or not). Age and geographical factors (Yeongdong and Yeongseo) were injected as control variables to see how they affect them. Furthermore, empirical analysis was conducted by setting up a hypothesis that the characteristics of start-up companies and subsequent support between start-up performance would have a positive intermediary effect. The research results showed that the remaining characteristics, except for education completion, had a positive impact on sales, and that the more participation in government projects, the longer the duration of the company's existence. In addition, the level of participation in government support projects was significant in the direction of the government. The analysis results of the parameter, follow-up support, had a positive impact on the start-up performance, and the subsequent support mediating effect showed the mediating effect of the start-up performance, except for geographical factors. The results of this study suggest the need for customized support suitable for the characteristics of youth start-ups in order to enhance the performance of young start-ups. Support agencies need to refer to corporate characteristics for smooth management and selection. In the Gangwon-do area, the government should seek to provide timely and organic support for start-up companies in order to produce successful start-up cases.

A Case Study of 'Smart Farm' Model Product Manufacturing and Recognition of Model Manufacturing Lesson Based on IoT(Internet of Things) by Pre-service Technology Teachers (예비기술교사를 대상으로 한 사물인터넷 기반의 모형 제작 수업에 대한 인식 및 '스마트 농장' 제작 사례 분석)

  • Kim, Seong-Il;Choi, Woon-Shik;Kim, Ki-Sun;Hwang, Sun-jong;Ju, Eun-Hee;Kang, Huyn-Jong
    • 대한공업교육학회지
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    • v.43 no.1
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    • pp.158-176
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    • 2018
  • The purpose of this study is to analyze the satisfaction of the manufacturing process and the satisfaction of manufacturing lesson in the lesson of model product manufacturing based on IoT(Internet of Things) for pre-service technology teachers. and we also analyzed 'smart farm' model production manufacturing among various products. The survey questionnaires with 8 questions to investigate satisfaction level of model manufacturing process, difficulties in manufacturing, and the satisfaction level of manufacturing lesson were collected from the 15 pre-service technology teachers and analyzed by using SPSS program. and The results of this study were as follows: First, the lesson satisfaction average level of pre-service technology teachers was high(M=4.22) in model product manufacturing process for the 'smart farm' model making based on the IoT. Second, the average satisfaction level of 'patent search and prior art search report writing education' was as high as 4.07. Therefore, the application of 'prior art search report writing education' showed that it helped to make the product. Third, the best high satisfaction level in the model production manufacturing procedure was 'education of inventive thinking method'(M=4.40). Therefore, the pre-service technology teachers showed that the 'education of inventive thinking methods' was very helpful from the idea design to the optimal selection of idea. The next order of satisfaction level was high(M=4.33) in 'design education and counseling' and 'guidance through selection of professor who guide the production manufacturing in addition to professors who are in charge of lesson'. Because they were helpful in solving the lack of knowledge of pre-service technology teachers. Fourth, satisfaction level with 'the presentation of model making results and exhibitions', 'presentations and participations of external event' was high (M = 4.13). Although the results of interviews with pre-service technology teachers showed that they suffered from lack of knowledge in various technologies, but it was an opportunity to learn things and felt a sense of accomplishment.

The Effect of Lime and Wollastonite on an Acid Sulfate Soil (특이산성토에 대한 석회 및 규회석의 효과)

  • Park, Nae Joung;Park, Young Sun;Lee, Kyu Ha;Kim, Yung Sup
    • Korean Journal of Soil Science and Fertilizer
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    • v.5 no.1
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    • pp.25-32
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    • 1972
  • The effects of limestone and wollastonite on an acid sulfate soil were studied. In addition, the effect of wollastonite was analyzed in terms of those due to calcium and to silica in the paddy field and in the laboratory with equivalent amounts of lime and wollastonite on a calcium basis. 1. Lime and wollastonite as liming materials were equally effective in neutralizing the soil acidity. 2. Lime, however was more reactive, raising the pH up to neutralization point in three days under waterlogged conditions at $25^{\circ}C$, in the lab study, and introduced alkali damage to transplanted rice seedlings showing marked restrictions of tillering in the field even though lime was applied two weeks before transplanting. On the other hand, wollastonite reacted very slowly, taking one week to two weeks to reach neutralization even when thoroughly mixed, and did not restrict the tillering. 3. Both lime and wollastonite effectively reduced the toxic aluminium in soil as well as in the soil solution but not always in the case of ferrous iron. However the reduction effect of the toxic substances in the experimental field was not so great as expected, because typical toxic symptoms were mild only. 4. Lime considerably increased the availability of silica in soil resulting in an increase of silica content in straw. Wollastonite released extra available silica itself resulting in a greater uptake of silica. 5. Increase of silica uptake by these materials was effective in reducing rate of infection of neck blast and resulted in higher rate of ripening, and in turn increased the paddy yield. 6. Application of either one significantly diminished the effect of the other. 7. Wollastonite markedly increased tillering in the early growing stage, but decreased the rate of effective tillers finally, resulting in about the same number of ears per hill at harvesting. 8. These liming materials appear to increase the number of grains per panicle slightly.

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Studies on the Solubility Phenomenon and Activities of Silk Cocoon Sericin through the Filature Water Conditions. (제사용수의 수질이 견층세리신의 용해에 미치는 거동구명에 관한 연구)

  • 김병호
    • Journal of Sericultural and Entomological Science
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    • v.16 no.2
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    • pp.77-98
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    • 1974
  • This study was carried out ill an attempt to investigate the properties and activities of sericin obtained from silk cocoon shells in silk reeling water through various instrumental analyses. In addition, the effects of the characteristics in sericin solubility on the reeling process and silk qualities were also studied on the basis of tile above conditions. The results obtained are as follows: I. The sericin properties and activities through various analytical instruments. 1. The water solubility of each amino acid such as serine, glycine. glutamic and aspartic acids against the pH modified water by using automatic amino acid analyzer, showed the lowest solubility at PH 5, but it increased according to drifting toward the alkalinity. 2. When the obtained sericin particles by water pH variation were observed with the electronic microscope, it was found for the sericin Particles to expand in the alkaline regions. 3. The IR spectrum results showed the differences among the pH modified sericin solutions at the range of 2,100cm-1 and 1.890cm-1 of wave number. 4. The existence of sericin with in silk fabrics made differences in the X-ray interference intencity, that is, the non-degummed fabrics had the interference peak at 2$\theta$=14$^{\circ}$, 17$^{\circ}$, 24$^{\circ}$, and the degummed ones had it at 2$\theta$=17$^{\circ}$, 18$^{\circ}$, 20$^{\circ}$, 23$^{\circ}$, 26$^{\circ}$. II. The results of sericin solubility for silk reeling process. 1. The sericin solubility and swelling had a tendency to increase up with high M-alkalinity and pH value of water. But in case of acidity. water hardness and concentration of ethylene glycol were high, the sericin solubility and swelling were decreased. 2. With the filature experiments, the best conditions of filature orator are summarized as fellows ; a. pH; 6.9${\pm}$0.2 d. acidity; below10ppm b. total hardness; 55:5ppm e. Fe ion; none c. M-alkalinity; 40${\pm}$10ppm

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Significance and Limitations of the Public Participatory National R&D Project: A Case Study on X-Project (국민참여형 국가연구개발사업의 의미와 한계: X-프로젝트 사례를 중심으로)

  • Park, Seongwon;Jin, Seola
    • Journal of Technology Innovation
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    • v.24 no.4
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    • pp.55-99
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    • 2016
  • The paper investigates X-project, in which the public was invited to participate in a national R&D project, examines how X-project attracted the public's attention and involved them in a national R&D project, and discusses the significance and limitations of X-project. X-project was executed by a 12 citizen-led committee, financially supported by the Ministry of Science, ICT, and Future Planning, and backed by the Science and Technology Policy Institute. People raised 6,212 questions that reflected the severe needs they experienced in their daily lives through the online and offline platforms of X-project. In addition, the committee members, scholars, experts, government officials, and citizens gathered together to select the fifty most provocative and novel of the questions raised by the public, and invited public participation to answer the questions in innovative ways. 310 research teams including professional researchers from universities and institutes, high-school students, lay persons, and corporate workers applied for X-project, and 54 of these teams were finally selected to receive funding from the government. Through planning and conducting X-project, as well as interviewing and surveying the participants in X-project and non-participants, we found that there was an enormous social consensus on the necessity of public participatory national R&D projects. People asserted that science and technology should put a greater focus on solving social problems and satisfying public needs. We also confirmed that the public could take part in national R&D projects. Most of all, we found that the questions raised by the public were very challenging, novel, and complex, and thus researchers need break-through approaches to address them. It can be also argued that through experiencing the X-project citizens can regard themselves as ones who are not only recipients of the benefits of the development of science and technology, but also contributors of the development of them. We finally argue that there are some limitations to X-project in terms of how to provide diverse incentives that attract more participation, how to develop the process in which people got involved in the project in more easy ways, and how to create new ways for lay persons and professional researchers to cooperate in solving social problems.