• 대한두개안면성형외과학회지
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• 제17권2호
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• pp.45-50
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• 2016

Extensive surgical resection of the aerodigestive track can result in a large and complex defect of the oropharynx, which represents a significant reconstructive challenge for the plastic surgery. Development of microsurgical techniques has allowed for free flap reconstruction of oropharyngeal defects, with superior outcomes as well as decreases in postoperative complications. The reconstructive goals for oral and oropharyngeal defects are to restore the anatomy, to maintain continuity of the intraoral surface and oropharynx, to protect vital structures such as carotid arteries, to cover exposed portions of internal organs in preparation for adjuvant radiation, and to preserve complex functions of the oral cavity and oropharynx. Oral and oropharyngeal cancers should be treated with consideration of functional recovery. Multidisciplinary treatment strategies are necessary for maximizing disease control and preserving the natural form and function of the oropharynx.

• 약학회지
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• 제43권5호
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• pp.665-673
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• 1999

This study was performed in order to investigate the effect of ketanserin, a specific antagonist of 5-HT2 receptor, on renal function in dogs. Ketanserin (50.0 and $150.0{\;}\mu\textrm{g}/kg$), when given intravenously, produced antidiuretic action accompanied with the decreased amounts of sodium and potassium excreted in urine (ENa, EK) and the increased reabsorption rates of sodium and potassium in renal tubules (RNa, RK). Ketanserin (50.0 and $50.0{\;}\mu\textrm{g}/kg$), when administered into a renal artery, elicited antidiuretic action in both experimental and control kidney, this time changes of renal function showed the same aspect as when given intravenously. Ketanserin (15.0 and $50.0{\;}\mu\textrm{g}/kg$) injected into the carotid artery exhibited also antidiuretic action and this antidiuretic action was not affected by renal denervation. Above results suggest that ketanserin elicits antidiuretic through central function, this central antidiuretic action is not mediated by renal nerves.

• Nuclear Medicine and Molecular Imaging
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• 제41권2호
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• pp.85-90
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• 2007

Acute event in cerebrovascular disease is the second most common cause of death in Korea following cancer, and it can also cause serious neurologic deficits. Understanding of perfusion status is important for clinical applications in management of patients with cerebrovascular diseases, and then the attacks of ischemic neurologic symptoms and the risk of acute events can be reduced. Therefore, the normal vascular anatomy of brain, various clinical applications of acetazolamide-enhanced brain perfusion SPECT, including meaning and role of assessment of vascular reserve in carotid stenosis before procedure, in pediatric Moyamoya disease before and after operation, in prediction of development of hyperperfusion syndrome before procedure, and in prediction of vasospasm and of prognosis in subarachnoid hemorrahge were reviewed in this paper.

• The Korean Journal of Pain
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• 제26권2호
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• pp.169-172
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• 2013

Eagle's syndrome is a disease without a clear lesion that is associated with repeated episodes of pharyngalgia, odynophagia, the sensation of a foreign body in the pharynx, tinnitus, and otalgia in which patients displaying these types of symptoms must be given a differential diagnosis. It is known to be characterized by styloid process elongation or increasing compression to adjacent anatomical structures through stylohyoid ligament calcification. In serious cases, continuous pressure to the carotid artery can lead to a stroke. Diagnosis is confirmed through clinical symptoms, radiological findings, and physical examinations. The most common type of treatment consists of a surgical excision of elongated styloid process. Nonetheless, this study presents a case of treating Eagle's syndrome with conservative management.

• Journal of Chest Surgery
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• 제49권5호
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• pp.392-396
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• 2016

We report a case of aortic dissection masquerading as acute ischemic stroke followed by intravenous thrombolysis. A 59-year-old man presented with dizziness. After examination, the patient had a seizure with bilateral Babinski signs. Soon after identifying multiple acute infarctions in both hemispheres on diffusion-weighted brain magnetic resonance (MR) imaging, tissue plasminogen activator (t-PA) was administered. Both common carotid arteries were invisible on MR angiography, and subsequent chest computed tomography revealed an aortic dissection. The emergency operation was delayed for 13 hours due to t-PA administration. The patient died of massive bleeding.

• 한국임상수의학회지
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• 제12권1호
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• pp.853-860
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• 1995

Two cases of guttural pouch mycosis in race horses were observed for clinical and pathological aspects of the disease to investigate etiology and pathogenesis of dysphagia and epistaxis of the horse. In case 1 showing prolonged dysphagic sign a diphtheritic membrane was confined to the guttural pouch involved with neuritis of the glossopharyngeal nerve due to fungal penetration. The other horse showing fatal recurrent epistaxis had lesion of mycetoma invading the internal carotid artery to provoke erosion of the artery. An Aspergillosis sp. was isolated from the guttural pouches of the two horses and identified as A nidulans.

• 생약학회지
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• 제1권1호
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• pp.25-32
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• 1970

Decursin, decursinol and nodakenin which were isolated from the root of Angelica gigas $N_{AKAI}$ (Umbelliferae) that is used as a botanical drug Dang-Gui (當歸) in Korea show following general pharmacologic activities. Decursin and decursinol increased the motility of the excised duodenum of the rabbit, but nodakenin did not. All of these three compounds depressed the heart contraction of the frog and blood pressure of the carotid artery and respiration of the rabbit. Decursin increased uterus contraction of the rabbit, but decursinol depressed it. And the tonus of the muscle of the earth worm was increased by decursinol, but was decreased by decursin.

• Biomolecules & Therapeutics
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• 제10권4호
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• pp.218-223
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• 2002

This study compared the blood-brain barrier permeability of [$^3H$] taurine in senescence-accelerated mouse (SAM) and normal mouse with common carotid artery perfusion (CCAP) method and intravenous injection technique to establish a possible relation between aging and changes in tissue levels of taurine. The SAM strains show senescence acceleration and age-associated pathological phenotypes similar to geriatric disorders seen in humans. In the result of this experiments, the plasma clearance of [$^3H$]taurine in SAM was almost comparable with that of normal mice by intravenous injection technique, but the brain volume of distribution ($V_{D brain}$) of [$^3H$]taurine in SAM by CCAP method reduced by 85% compared with that in normal mice. These results suggest that aging may have an effect on the brain transport activity of taurine in disease state model animal.

• Journal of Korean Neurosurgical Society
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• 제39권6호
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• pp.455-458
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• 2006

Rhinocerebral mucormycosis is rare, but fatal infection of the nasal cavity and sinuses. It can spread to the orbits and cranium within days, and prognosis is directly associated with length of time before diagnosis and treatment. Rhinocerebral mucormycosis can cause cerebral infarction via carotid a artery occlusion. Therefore, neurosurgeon is paramount in making the proper management. We recently encountered a case of rhinocerebral mucormycosis with massive cerebral infarction. The clinical and radiological details of this case are presented here with a brief review of the literature.

• Journal of Korean Neurosurgical Society
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• 제30권sup2호
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• pp.368-372
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• 2001

Arteriovenous malformations of the face and scalp are uncommon. We report a patient with facial AVM feeding from external carotid artery. This 26-year old man presented with an arteriovenous malformation involving left forehead. The patient first noted a coin-sized lesion on the site 20 years previously after blunt trauma which progressively enlarged. Surgical resection of AVM was performed after ligation of feeding artery.