Massive Cerebral Infarction Due to Rhinocerebral Mucormycosis

  • Kwak, Seung-Won (Department of Neurosurgery, Our Lady of Mercy Hospital, College of Medicine, The Catholic University of Korea) ;
  • Kim, Jong-Tae (Department of Neurosurgery, Our Lady of Mercy Hospital, College of Medicine, The Catholic University of Korea) ;
  • Chung, Dong-Sup (Department of Neurosurgery, Our Lady of Mercy Hospital, College of Medicine, The Catholic University of Korea)
  • Published : 2006.06.30

Abstract

Rhinocerebral mucormycosis is rare, but fatal infection of the nasal cavity and sinuses. It can spread to the orbits and cranium within days, and prognosis is directly associated with length of time before diagnosis and treatment. Rhinocerebral mucormycosis can cause cerebral infarction via carotid a artery occlusion. Therefore, neurosurgeon is paramount in making the proper management. We recently encountered a case of rhinocerebral mucormycosis with massive cerebral infarction. The clinical and radiological details of this case are presented here with a brief review of the literature.

Keywords

References

  1. Abunijem ZM, Al-Shohaib S, Morrow LB : Rhinocerebral mucormycosis. Ann Saudi Med 15 : 496-500, 1995 https://doi.org/10.5144/0256-4947.1995.496
  2. de Biscop J, Mondie JM, Venries de la Guillaumie B, Peri G : Mucormycosis in an apparently normal host : case study and literature review. J Craniomaxillofac Surg 19 : 275-278, 1991 https://doi.org/10.1016/S1010-5182(05)80070-8
  3. Bodenstein NP, McIntosh WA, Vlantis AC, Urquhart AC : Clinical signs of orbital ischemia in rhino-orbitocerebral mucormycosis. Laryngoscope 103 : 1357-1361, 1993
  4. Couch L, Theilen F, Mader JT : Rhinocerebral mucormycosis with cerebral extension successfully treated with adjunctive hyperbaric oxygen therapy. Arch Otolaryngol Head Neck Surg 114 : 791-794, 1988 https://doi.org/10.1001/archotol.1988.01860190095032
  5. Delbrouck C, Jacobs F, Fernandez Aguilar S, Devroede B, Choufani G, Hassid S : Carotid artery occlusion due to fulminant rhinocerebral mucormycosis. Acta Otorhinolaryngol Belg 58 : 135-140, 2004
  6. Rogers WD Jr : Facial paralysis and epistaxis in a diabetic : a typical presentation for rhinocerebral mucormycosis. Ann Emerg Med 13 : 560-561, 1984 https://doi.org/10.1016/S0196-0644(84)80533-8
  7. Schwartz JC : Rhinocerebral mucormycosis : three case reports and subject review. J Emerg Med 3 : 11-19, 1985 https://doi.org/10.1016/0736-4679(85)90213-6
  8. Shin PJ, Lee HK, Kim CH, Yang KH, Hwang DY : Rhinocerebral mucormycosis with intracerebral hemorrhage. J Korean Neurosurg Soc 29 : 136-142, 2000
  9. Soloniuk DS, Moreland DB : Rhinocerebral mucormycosis with extension to the posterior fossa : case report. Neurosurgery 23 : 641-643, 1988 https://doi.org/10.1227/00006123-198811000-00017
  10. Sugar AM : Mucormycosis. Clin Infect Dis (Suppl 1) 14 : S126-129, 1992 https://doi.org/10.1093/clinids/14.Supplement_1.S126
  11. Yohai RA, Bullock JD, Aziz AA, Markert RJ : Survivial factors in rhino-orbital-cerebral mucormycosis. Surv Ophthalmol 39 : 3-22, 1994 https://doi.org/10.1016/S0039-6257(05)80041-4
  12. Yoo BG, Lim KI, Kim KS, Yoo KM : A case of bilateral cavernous sinus mucormycosis. J Korean Neurol Assoc 14 : 668-673, 1996
  13. Young RF, Gade G, Grinnell V : Surgical treatment for fungal infections in the nervous system. J Neurosurg 63 : 371-381, 1985 https://doi.org/10.3171/jns.1985.63.3.0371