• Asian Pacific Journal of Cancer Prevention
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• v.15 no.9
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• pp.4033-4037
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• 2014

Emerging evidence has shown associations of microRNA-205 (miR-205) with crucial cell processes such as the epithelial-mesenchymal transition (EMT) and aberrant expression with tumorigenesis in many types of human malignancy. This prospective study characterized the contribution of miR-205 to the colorectal cancer (CRC) tumorigenesis. The real-time reverse transcription-polymerase chain reaction was used to examine miR-205 levels prospectively in 36 pairs of samples of CRC tissue and adjacent noncancerous tissue (>2 cm from cancer tissue). In addition, the relationship between miR-205 levels and clinicopathological features was explored. The capability of miR-205 to function as a tumor marker was also examined. miR-205 expression levels did not show significant changes overall. However, miR-205 was significantly downregulated in a group of CRC samples compared with matched noncancerous tissue samples. Moreover, decreased miR-205 correlated significantly with lymphatic metastasis. A receiver operating characteristic (ROC) curve also showed an optimum cut off point of $1.4{\times}10^{-3}$ to distinguish lymphatic metastatic CRCs from non-metastatic CRCs. Interestingly we found lymphatic metastasis in almost 80% of the depressed samples. This study suggested that miR-205 could be reduced in the majority of metastatic CRCs and the risk of CRC metastasis may be predicted by monitoring miR-205 in patient samples collected at the time of the initial diagnosis. Therefore, targeting miR-205 and its potential environmental activators might be a promising therapeutic option to prevent malignant progression toward metastasis.

• Journal of Korea Water Resources Association
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• v.37 no.7
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• pp.569-579
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• 2004

Recently, the extreme drought is often occurred due to the global warming and the serious weather changes. Also, the problems of the water pollution In the developed areas, the oppositions from people in the upper stream area and water concession from the local governments affect the national request to get more clean water resources in upper stream of the undeveloped areas. It also brings on the necessity of recognition for water supply managements. Therefore, as the water demand is rapidly changes in the metropolitan areas, the capability of water supply from the north Han river basin dams should be appropriately investigated. In this study, we developed a simulation system using STELLA (equation omitted) software environment, a shared vision model, to analyze the possibility of the stable water supply from north Han river basin dams. Also, three different rules are applied on this model by dividing the water level to minimum(Rule 1), medium(Rule 2) and maximum(Rule 3). Using the rules, the safety yield changes are analyzed for dam rule curve of the reservoir and hydropower release.

• Journal of Fashion Business
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• v.7 no.2
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• pp.55-68
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• 2003

The purpose of this research is to expand the realm of a button for a decorative purpose through embossing the effect and gravity of a button in fashion by designing the new ceramic buttons which are mainly used for decorative function in costume. In order to acquire a motif for the design, I analyzed several works of Gustav Klimt. As the result, those feature can be classified into the use of decorative lines, mosaic forms, and harmony of golden yellow and black, and it can be applied to buttons and clothes design. The sort of clay used in manufacturing the ceramic buttons was white clay to have high density and to diffuse light well, and press shaping techniques using plaster mold were employed. The baking was performed in an electronic kiln at $800^{\circ}C$ for the first time and at $1250^{\circ}C$ for the second time. Based on wearable designs in 2002/2003 F/W Trend of Interfashion Planning, I made three pieces of dress which could express the button's capability of decoration with effect. This is expressing a simplified form which shows up in details of and yellow and red pink were used to harmonize with golden yellow clothes. As an application of shapes of foliage in I transformed its size and form to be consistent with a jacket and a tube top. To accord with golden beige costume, I made a curve, showing up in Klimt's paintings, with golden color on a circle shape which was also a main motif in his paintings.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1085-1090
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• 2011

To assure the safety of rolling stock, it is important to perform the fatigue analysis of reduction gear unit in rolling stock considering a variation of velocity and traction motor capability. This paper presents fatigue analysis of the damage of reduction gear unit of railway vehicle under variable amplitude loading(VAL) based on quasi-static fatigue analysis using finite element model and linear Miner's rule. The VAL for the simulation was constructed from the tractive effort curve and train run curves of railway vehicle under commercial operation condition using MSC.ADAMS dynamic analysis. The finite element model for evaluating the carburizing effect on the gear surface was used for predicting the fatigue life of the middle gear based on strain-life based approach. The results showed that the frequent high starting torque due to a quick start as well as increasing numbers of stops at station would decrease the fatigue life of reduction gear unit.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.35 no.1
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• pp.11-15
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• 2011

In this paper, a methodology for the power control of a wind turbine, which is the variable-speed and variable-pitch (VSVP) control system, is introduced. This control methodology maximizes the capability of the turbine to extract maximum power from the wind in the regions with low wind speeds. Further, it regulates the wind-turbine power as the rated power in the case of the regions with high wind speeds. A simple drive train model is used to design the VSVP control system. The methodology for VSVP control is mechanized by controlling the generator torque and blade pitch. Finally, some simulation results for the VSVP control to a MW wind turbine are discussed in this paper.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.221-221
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• 2013

Striving to replace the well known silicon nanocrystals embedded in oxides with solution-processable charge-trapping materials has been debated because of large scale and cost effective demands. Herein, a silicon quantum dot-polystyrene nanocomposite (SiQD-PS NC) was synthesized by postfunctionalization of hydrogen-terminated silicon quantum dots (H-SiQDs) with styrene using a thermally induced surface-initiated polymerization approach. The NC contains two miscible components: PS and SiQD@PS, which respectively are polystyrene and polystyrene chains-capped SiQDs. Spin-coated films of the nanocomposite on various substrate were thermally annealed at different temperatures and subsequently used to construct metal-insulator-semiconductor (MIS) devices and thin film field effect transistors (TFTs) having a structure p-$S^{++}$/$SiO_2$/NC/pentacene/Au source-drain. C-V curves obtained from the MIS devices exhibit a well-defined counterclockwise hysteresis with negative fat band shifts, which was stable over a wide range of curing temperature ($50{\sim}250^{\circ}C$. The positive charge trapping capability of the NC originates from the spherical potential well structure of the SiQD@PS component while the strong chemical bonding between SiQDs and polystyrene chains accounts for the thermal stability of the charge trapping property. The transfer curve of the transistor was controllably shifted to the negative direction by chaining applied gate voltage. Thereby, this newly synthesized and solution processable SiQD-PS nanocomposite is applicable as charge trapping materials for TFT based memory devices.

• Journal of the Korean Operations Research and Management Science Society
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• v.40 no.1
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• pp.5-19
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• 2015

Literatures on open innovation have two major limitations. First, either on a firm level or on an industry level did they analyze the open innovation issues. The results of a firm's innovation can be diffused through the whole network and the firm can learn back from the network knowledge. Prior literatures did not consider the feedback loop among firms and network in which the firms are involved. Second, most open innovation research had a static perspective on firm's innovation performance. Since the diffusion, spill-over and learning among network members are involved over time, the open innovation is intrinsically dynamic. From the dynamic perspective, we can appreciate the fundamental attributes of the open innovation network which involves diverse firms, research institutes, and universities. In order to overcome the limitations, we suggest a dynamic model for open innovation network. We build an agent-based model which consists of heterogeneous firms. The firms are connected through a scale-free network which is formed by preferential attachment. Through the diverse scenario of simulation, we collect massive data on the firm level and analyze them both on firm and industry level. From the analysis, we found that, on industry level, the overall performance of open innovation increases as the internal research capability, absorptive capacity, and learning curve coefficient increase. Noticeably, as the deprecation rate of knowledge increases, the variability of knowledge increases. From the firm level analysis, we found that the industry-level variables had a significant effect on the firm's innovation performance lasting through all the time, whereas the firm-level variables had only on the early phase of innovation.

• Journal of the Korean Association of Geographic Information Studies
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• v.17 no.4
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• pp.156-166
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• 2014

As of 2014, KARI (Korea Aerospace Research Institute) operates two high-resolution satellites such as Kompsat-2 and Kompsat-3. Kompsat-3 has capability of in-track stereo images acquisition but it is quite limited because the stereo mode lowers the spatial coverage in a trajectory. In this paper we analyze the epipolar geometry from the heterogeneous Kompsat-2 and Kompsat-3 image combination to epipolar resample them for 3D spatial data acquisition. The analysis was carried out using the piecewise approach with RPCs (Rational Polynomial Coefficients) and the result showed the parabolic epipolar curve pattern. We also concluded that the third order polynomial transformation is required for epipolar image resampling. The resampled image pair showed 1 pixel level of y-parallax and can be used for 3D display and digitizing.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.6
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• pp.55-61
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• 2014

This paper related with the ECMA (Enchanced CMA) algorithm performance which is possible to simultaneously compensation of the amplitude and phase by appling the minimum disturbance techniques in the CMA adatpve equalizer. The ECMA can improving the gradient noise amplification problem, stability and roburstness performance by the minimum disturbance technique that is the minimization of the equalizer tap weight variation in the point of squared euclidiean norm and the decision directed mode, and then the now cost function were proposed in order to simultaneouly compensation of amplitude and phase of the received signal with the minimum increment of computational operations. The performance of ECMA algorithm was compared to present MCMA by the computer simulation. For proving the performance, the recovered signal constellation that is the output of equalizer output signal and the residual isi and Maximum Distortion charateristic and MSE learning curve that are presents the convergence performance in the equalizer and the overall frequency transfer function of channel and equalizer were used. As a result of computer simulation, the ECMA has more better compensation capability of amplitude and phase in the recovered constellation, and the convergence time of adaptive equalization has improved compared to the MCMA.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.3
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• pp.63-68
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• 2014

This paper related with the I-CMA (Improved-CMA) algorithm that is possible to compensates of phase in CMA adatpve equalizer which is used for the elemination of intersymbol interference in the multipath fading and band limit characteristics of channel. The new cost function is proposed for the eliminate the amplitude and phase simulataneous by modifying the cost fuction for get the error signal in present CMA algorithm. It has a merit to the algorithm simplicities and eliminats the PLL device for phase compensation after equalization. For proving this, the recovered signal constellation that is the output of equalizer output signal and the residual isi and Maximum Distortion charateristic learning curve that are presents the convergence performance in the equalizer and the overall frequency transfer function of channel and equalizer were used. As a result of computer simulation, the I-CMA has more good compensation capability of amplitude and phas in the recovered constellation. But the convergence time is slow due to the simultaneously phase compensation.