• 대한가정학회지
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• 제34권2호
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• pp.315-328
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• 1996

The purpose of this study was to examine how children's sibling relationships were related to their self-esteem. 440 children and their only siblings were asked to respond to two questionnaires concerning the two research variables. The questionnaires used were the SRQ (Furman & Buhrmester, 1985) and the SPPC (Harter, 1985). Ther data were analyzed through correlation analyses, stepwise multiple regression analyses, and canonical correlation analyses. The results were as follows : Warmth·Intimacy and Rivalry (parental partiality toward the child himself/herself) had positive correlations with the child's self-esteem, while sibling Conflict had negative correlations and Relative Status·Power had little correlation. The best predictor of children's self-esteem was sibling Warmth·Intimacy. The next powerful determinants were Conflict and Rivalry. Among the six self-esteem measures, the one predicted best by sibling relationships was Global Self-Worth. The next ones were Behavior·Conduct and Scholastic Competence. The findings revealed that the predictive power of the sibling relationships factors varied considerably according to such status variables as sex and birth order of children and to whether each of the two research variables was analyzed as a whole or at a factor level.

• 대한가정학회지
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• 제29권1호
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• pp.125-137
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• 1991

This study aims to offer basic data for development of the three generations sharing house plan, through finding out the relationship between family characteristics and the housing needs of the middle aged living in the middle and small cities. The 1029 questionnaires were used for this study, and data were analysed by canonical correlation analysis, factor analysis and multiple regression. The results are as follows. Their family characteristics influence housing needs for the three generations sharing house. Especially groups of female, neuclear family, family of higher S.E.S., less number of children. family living in the apartment houses and owner occupied house prefer more privacy between generations in the three generations sharing house.

• 한국의류학회지
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• 제26권7호
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• pp.982-992
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• 2002

The purpose of this study is to investigate the clothing memory which affects apparel purchase behavior. The construction of clothing memory, the relationship between clothing memory and apparel purchase behavior, and the difference of clothing memory among persons by demographic variables are examined 746 female apparel consumers answer the questionnaire and data are analyzed by factor analysis, canonical correlation, Pearson correlation, and t-test. The result of this study are as follows; 1. There are three dimensions in the clothing memory which memory apparel purchase behavior; general memory about clothing, memory of appropriate clothing for oneself and memory of apparel purchase. 2. nothing memory affects apparel purchase behavior. General memory about clothing plays the most important role in the apparel purchase behavior especially in the amount of apparel purchase. 3. Unmarried young women with high income, high education level, and decent job have large amount of clothing memory.

• 한국정보전자통신기술학회논문지
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• 제11권5호
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• pp.475-480
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• 2018

In OFDM-based systems, FFT is a critical component since it occupies large area and consumes more power. In this paper, we present a low hardware-cost and low power 512-point pipelined FFT design method for OFDM applications. To reduce the number of twiddle factors and to choose simple design architecture, the radix-$2^4-2^3$ algorithm are exploited. For twiddle factor multiplication, we propose a new canonical signed digit (CSD) complex multiplier design method to minimize the hardware-cost. In hardware implementation with Intel FPGA, the proposed FFT design achieves more than about 28% reduction in gate count and 18% reduction in power consumption compared to the previous approaches.

• Communications for Statistical Applications and Methods
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• 제22권5호
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• pp.415-434
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• 2015

In this paper we overview the literature on common features analysis of economic time series. Starting from the seminal contributions by Engle and Kozicki (1993) and Vahid and Engle (1993), we present and discuss the various notions that have been proposed to detect and model common cyclical features in macroeconometrics. In particular, we analyze in details the link between common cyclical features and the reduced-rank regression model. We also illustrate similarities and differences between the common features methodology and other popular types of multivariate time series modelling. Finally, we discuss some recent developments in this area, such as the implications of common features for univariate time series models and the analysis of common autocorrelation in medium-large dimensional systems.

• Molecules and Cells
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• 제45권11호
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• pp.763-770
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• 2022

Caenorhabditis elegans has been used as a major model organism to identify genetic factors that regulate organismal aging and longevity. Insulin/insulin-like growth factor 1 (IGF-1) signaling (IIS) regulates aging in many species, ranging from nematodes to humans. C. elegans is a nonpathogenic genetic nematode model, which has been extensively utilized to identify molecular and cellular components that function in organismal aging and longevity. Here, we review the recent progress in the role of IIS in aging and longevity, which involves direct regulation of protein and RNA homeostasis, stress resistance, metabolism and the activities of the endocrine system. We also discuss recently identified genetic factors that interact with canonical IIS components to regulate aging and health span in C. elegans. We expect this review to provide valuable insights into understanding animal aging, which could eventually help develop anti-aging drugs for humans.

• 한국보건간호학회지
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• 제3권1호
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• pp.18-37
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• 1989

This study was done in order to analyze the factors which influenced the performance level of community health practitioners' task. Interview survey was done during the period from August to October, 1986. Interviewee were 166 CHPs among total of 217 CHPs in Kyonggi province area. Multiple stepwise regression and canonical correlation analysis were used to identify major factors influenced to perform community health practitioners' task. The results of this study were summarized as follows: 1. General characteristics of CHPs 1) Personal characteristics The average age of CHPs was 37.8 years and their marital status was $77.6\%$ of married, educational back-ground was $65.3\%$ of junior college graduation. Their job career was $38.6\%$ of between 1-3 years, $33.3\%$ of between 3-5 years, $22.2\%$ of less than 1 years. Most of CHPs$(62.8\%)$ were fully satisfied with their job, $33.3\%$ were moderately, and $3.8\%$ were not satisfied. 2) Working environmental condition Only $31.7%$ of CHPs were satisfied with their working condition of primary health post, $26.6\%$ were not satisfied. Half of CHPs$(52.5\%)$ replied having good cooperation with health center, $10.1\%$ replied bad. Cooperation with health subcenter was good in $32.9\%$, and bad in $21.9%$. Cooperation with private health institutions was good in $34.2\%$, bad in $21.6%$. 2. Performance level of community health practitioners' task Among a total of 52 contents of their functions medical history taking. physical examination, referral of diagnostic laboratory work-up($(86.4\%)$, health assessment of pregnant women$(82.1\%)$, development of health information system$(79.4\%)$, supervision of health workers $(78.4\%)$, follow-up of family planning acceptors$(77.3\%)$, and follow-up of family planning acceptors' side effects$(77.3\%)$ were actively performed. Diagnosis of pregnancy$(62.1\%)$, sampling of drinking water for quality test$(52.5\%)$, making list of equipment' & supplies $(51.5\%)$, evaluation of primary health post activities $(37.6\%)$, organization of village health workers$(32.4\%)$ and management of village health workers $(30.1\%)$ were poorly performed. 3. Stepwise multiple regression analysis of job function The factors which influenced the performance level of community health practitioners' function were age, marital status, educational level, job career, job satisfaction, satisfaction of working environment of primary health post, cooperation of health center, cooperation of health center, cooperation of private health instiutions in orders. These 9 variables were able to explain job function from $25.7\%$ of program planning to $6.7\%$ of management of common disease. 4. Canonical correlation analysis between the performance of function and general characteristics of CHPs. Cooperation of private health institutions was found to be the factor influencing task performance of community organization, management of primary health post, technical supervision of health personnels. Job satisfaction of CHPs was also found to be the factor influencing task performance of family planning, management of common disease and maintenance of health information system.

• 아동학회지
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• 제17권1호
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• pp.189-212
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• 1996

The purpose of this study was to investigate how parental childrearing behavior and children's sibling relationships are related to children's self-esteem. 440 middle class families consisting of two children and their parents were the subjects of this study. The research instruments included a childrearing behavior questionnaire, the Sibling Relationships Questionnaire (Furman & Buhrmester, 1985), and the Self-Perception Profile for Children (Harter, 1985). Analyses of the data included correlation analysis, canonical correlation, regression, stepwise multiple regression, and MANOVA with stepwise discriminant analysis as the follow-up test. The most powerful predictors of children's self-esteem were the Warmth-Acceptance of childrearing behavior and the Warmth-Closeness of sibling relationships. The self-esteem dimension was best predicted by parental childrearing behavior and by children's sibling relationships was Global Self-Worth. Behavioral Conduct was best predicted by the Rejection-Restriction factor of childrearing, and by Conflict (for boys) and Rivalry (for girls) factors of sibling relationships. Children's self-esteem was related more strongly to the Warmth-Acceptance and the Rejection-Restriction of opposite-sex parents. The effects of Permissiveness-Nonintervention were stronger in same-sex parent-child dyads. Parental childrearing behaviors accounted for boy's self-esteem better than girl's with the exception of Behavioral Conduct. Sibling relationships accounted for girl's self-esteem better than boy's. The $2{\times}2$ MANOVA revealed interaction effects of parental childrearing behaviors and sibling relationships on children's self-esteem. Two factors of Rivalry and Conflict in sibling relationships and all three factors of childrearing behaviors showed significant interaction effects, The childrearing factor of Permissiveness-Nonintervention and the sibling factor of Rivalry, which were relatively weak predictors of self-esteem when acting alone, gained power in explaining children's self-esteem within the interactional context.

• Molecules and Cells
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• 제43권2호
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• pp.168-175
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• 2020

Runx2 is an essential transcription factor for skeletal development. It is expressed in multipotent mesenchymal cells, osteoblast-lineage cells, and chondrocytes. Runx2 plays a major role in chondrocyte maturation, and Runx3 is partly involved. Runx2 regulates chondrocyte proliferation by directly regulating Ihh expression. It also determines whether chondrocytes become those that form transient cartilage or permanent cartilage, and functions in the pathogenesis of osteoarthritis. Runx2 is essential for osteoblast differentiation and is required for the proliferation of osteoprogenitors. Ihh is required for Runx2 expression in osteoprogenitors, and hedgehog signaling and Runx2 induce the differentiation of osteoprogenitors to preosteoblasts in endochondral bone. Runx2 induces Sp7 expression, and Runx2, Sp7, and canonical Wnt signaling are required for the differentiation of preosteoblasts to immature osteoblasts. It also induces the proliferation of osteoprogenitors by directly regulating the expression of Fgfr2 and Fgfr3. Furthermore, Runx2 induces the proliferation of mesenchymal cells and their commitment into osteoblast-lineage cells through the induction of hedgehog (Gli1, Ptch1, Ihh), Fgf (Fgfr2, Fgfr3), Wnt (Tcf7, Wnt10b), and Pthlh (Pth1r) signaling pathway gene expression in calvaria, and more than a half-dosage of Runx2 is required for their expression. This is a major cause of cleidocranial dysplasia, which is caused by heterozygous mutation of RUNX2. Cbfb, which is a co-transcription factor that forms a heterodimer with Runx2, enhances DNA binding of Runx2 and stabilizes Runx2 protein by inhibiting its ubiquitination. Thus, Runx2/Cbfb regulates the proliferation and differentiation of chondrocytes and osteoblast-lineage cells by activating multiple signaling pathways and via their reciprocal regulation.

• BMB Reports
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• 제53권12호
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• pp.628-633
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• 2020

WNT11 is a member of the non-canonical Wnt family and plays a crucial role in tumor progression. However, the regulatory mechanisms underlying WNT11 expression are unclear. Tumor necrosis factor-alpha (TNFα) is a major inflammatory cytokine produced in the tumor microenvironment and contributes to processes associated with tumor progression, such as tumor invasion and metastasis. By using site-directed mutagenesis and introducing a serial deletion in the 5'-regulatory region of WNT11, we observed that TNFα activates the early growth response 1 (EGR1)-binding sequence (EBS) in the proximal region of WNT11 and that the transcription factor EGR1 is necessary for the TNFα-induced transcription of WNT11. EGR1 bound directly to the EBSs within the proximal 5'-regulatory region of WNT11 and ectopic expression of EGR1 stimulated WNT11 promoter activity, whereas the knockdown of EGR1 expression by RNA interference reduced TNFα-induced WNT11 expression in T47D breast cancer cells. We also observed that mitogen-activated protein kinases (MAPK), extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 kinase mediated TNFα-induced transcription of WNT11 via EGR1. Our results suggest that EGR1 directly targets WNT11 in response to TNFα stimulation in breast cancer cells.