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UNIFYING STATIONARY EQUATIONS FOR GENERALIZED CANONICAL CORRELATION ANALYSIS

  • Kang Hyun-Cheol;Kim Kee-Young
    • Journal of the Korean Statistical Society
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    • v.35 no.2
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    • pp.143-156
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    • 2006
  • In the present paper, various solutions for generalized canonical correlation analysis (GCCA) are considered depending on the criteria and constraints. For the comparisons of some characteristics of the solutions, we provide with certain unifying stationary equations which might to also useful to obtain various generalized canonical correlation analysis solutions. In addition, we suggest an approach for the generalized canonical correlation analysis by exploiting the concept of maximum eccentricity originally de-signed to test the internal independence structure. The solutions, including new one, are compared through unifying stationary equations and by using some numerical illustrations. A type of iterative procedure for the GCCA solutions is suggested and some numerical examples are provided to illustrate several GCCA methods.

m-CANONICAL IDEALS IN SEMIGROUPS

  • Kwak, Dong-Je;Kim, Myeong-Og;Park, Young-Soo
    • Bulletin of the Korean Mathematical Society
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    • v.37 no.3
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    • pp.577-586
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    • 2000
  • For a grading monoid S, we prove that (1) if (S, M) is a valuation semigroup, then M is an m-canonical ideal, that is, an ideal M such that M : (M:J)=J for every ideal J of S. (2) if S is an integrally closed semigroup and S has a principal m-canonical ideal, then S is a valuation semigroup, and (3) if S is a completely integrally closed and S has an m-canonical ideal I, then every ideal of S is I-invertible, that is, J+(I+J)=I for every ideal J of S.

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A MATRIX PENCIL APPROACH COMPUTING THE ELEMENTARY DIVISORS OF A MATRIX : NUMERICAL ASPECTS AND APPLICATIONS

  • Mitrouli, M.;Kalogeropoulos, G.
    • Journal of applied mathematics & informatics
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    • v.5 no.3
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    • pp.717-734
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    • 1998
  • In the present paper is presented a new matrix pencil-based numerical approach achieving the computation of the elemen-tary divisors of a given matrix $A \in C^{n\timesn}$ This computation is at-tained without performing similarity transformations and the whole procedure is based on the construction of the Piecewise Arithmetic Progression Sequence(PAPS) of the associated pencil $\lambda I_n$ -A of matrix A for all the appropriate values of $\lambda$ belonging to the set of eigenvalues of A. This technique produces a stable and accurate numerical algorithm working satisfactorily for matrices with a well defined eigenstructure. The whole technique can be applied for the computation of the first second and Jordan canonical form of a given matrix $A \in C^{n\timesn}$. The results are accurate for matrices possessing a well defined canonical form. In case of defective matrices indications of the most appropriately computed canonical form. In case of defective matrices indication of the most appropriately computed canonical form are given.

Microphone Type Classification for Digital Audio Forgery Detection (디지털 오디오 위조검출을 위한 마이크로폰 타입 인식)

  • Seok, Jongwon
    • Journal of Korea Multimedia Society
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    • v.18 no.3
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    • pp.323-329
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    • 2015
  • In this paper we applied pattern recognition approach to detect audio forgery. Classification of the microphone types and models can help determining the authenticity of the recordings. Canonical correlation analysis was applied to extract feature for microphone classification. We utilized the linear dependence between two near-silence regions. To utilize the advantage of multi-feature based canonical correlation analysis, we selected three commonly used features to capture the temporal and spectral characteristics. Using three different microphones, we tested the usefulness of multi-feature based characteristics of canonical correlation analysis and compared the results with single feature based method. The performance of classification rate was carried out using the backpropagation neural network. Experimental results show the promise of canonical correlation features for microphone classification.

Adaptive Observer Design for Nonlinear Systems Using Generalized Nonlinear Observer Canonical Form

  • Jo, Nam-Hoon;Son, Young-Ik
    • Journal of Mechanical Science and Technology
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    • v.18 no.7
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    • pp.1150-1158
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    • 2004
  • In this paper, we present an adaptive observer for nonlinear systems that include unknown constant parameters and are not necessarily observable. Sufficient conditions are given for a nonlinear system to be transformed by state-space change of coordinates into an adaptive observer canonical form. Once a nonlinear system is transformed into the proposed adaptive observer canonical form, an adaptive observer can be designed under the assumption that a certain system is strictly positive real. An illustrative example is included to show the effectiveness of the proposed method.

MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions

  • Seok, Heeyoung;Ham, Juyoung;Jang, Eun-Sook;Chi, Sung Wook
    • Molecules and Cells
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    • v.39 no.5
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    • pp.375-381
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    • 2016
  • MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and affect various biological phenotypes. Functional miRNA target recognition is known to majorly attribute specificity to consecutive pairing with seed region (position 2-8) of miRNA. Recent advances in a transcriptome-wide method of mapping miRNA binding sites (Ago HITS-CLIP) elucidated that a large portion of miRNA-target interactions in vivo are mediated not only through the canonical "seed sites" but also via non-canonical sites (~15-80%), setting the stage to expand and determine their properties. Here we focus on recent findings from transcriptome-wide non-canonical miRNA-target interactions, specifically regarding "nucleation bulges" and "seed-like motifs". We also discuss insights from Ago HITS-CLIP data alongside structural and biochemical studies, which highlight putative mechanisms of miRNA target recognition, and the biological significance of these non-canonical sites mediating marginal repression.

Relationships between Soil-Site Properties and Bamboo (Phyllostachys bambusoides) Growth (토양(土壤)의 이화학적(理化學的) 특성(特性)과 대나무 생장(生長)과의 관계(關係))

  • Chung, Young Gwan;Ramm, Carl W.
    • Journal of Korean Society of Forest Science
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    • v.79 no.1
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    • pp.16-20
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    • 1990
  • Canonical correlation analysis was used to relate 17 soil-site variables to bamboo diameter, height, and internodal characteristics. The first canonical correlation was highly significant, explained much of the variance in both sets of variables, and the canonical variates made sense biologically. Surface soil depth, total nitrogen and percent organic matter had high positive correlations with the first soil-site canonical variate. Clay content (%) and cation exchange capacity were negatively correlated with the first soil-site canonical variate. Only 8 of predictor variables were considered relevant for predicting bamboo growth.

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Structure and Stability of γ-Aminobutyric acid-(H2O)n (n = 0-5) Clusters: Zwitterionic vs. Canonical forms

  • Kim, Ju-Young;Schermann, Jean Pierre;Lee, Sung-Yul
    • Bulletin of the Korean Chemical Society
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    • v.31 no.1
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    • pp.59-63
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    • 2010
  • Calculations are presented for the $\gamma$-aminobutyric acid-$(H_2O)_n$ (n = 0-5) clusters in both canonical and zwitterionic forms. We examine the effects of microsolvation on the structures and transformation between the canonical and zwitterionic forms. The canonical forms are predicted to be more stable for n = 0-4. With five microsolvating water molecules, the two forms of $\gamma$-aminobutyric acid become quasidegenerate, with the energies of zwitterionic forms slightly (by 1 - 3 kcal/mol) higher. The lowest energy zwitterionic conformer of $\gamma$-aminobutyric acid-$(H_2O)_5$ cluster is calculated to isomerize to canonical form through a barrier-less proton transfer process and is thus predicted to be kinetically unstable. Therefore, we predict that the canonical conformers of $\gamma$-aminobutyric acid should be observed predominantly in the gas phase at low temperature in presence of up to five water molecules.

Deubiquitinase Otubain 1 as a Cancer Therapeutic Target (암 치료 표적으로써 OTUB1)

  • Kim, Dong Eun;Woo, Seon Min;Kwon, Taeg Kyu
    • Journal of Life Science
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    • v.30 no.5
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    • pp.483-490
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    • 2020
  • The ubiquitin system uses ligases and deubiquitinases (DUBs) to regulate ubiquitin position on protein substrates and is involved in many biological processes which determine stability, activity, and interaction of the target substrate. DUBs are classified in six groups according to catalytic domain, namely ubiquitin-specific proteases (USPs); ubiquitin C-terminal hydrolases (UCHs); ovarian tumor proteases (OTUs); Machado Joseph Disease proteases (MJDs); motif interacting with Ub (MIU)-containing novel DUB family (MINDY); and Jab1/MPN/MOV34 metalloenzymes (JAMMs). Otubain 1 (OTUB1) is a DUB in the OTU family which possesses both canonical and non-canonical activity and can regulate multiple cellular signaling pathways. In this review, we describe the function of OTUB1 through regulation of its canonical and non-canonical activities in multiple specifically cancer-associated pathways. The canonical activity of OTUB1 inhibits protein ubiquitination by cleaving Lys48 linkages while its non-canonical activity prevents ubiquitin transfer onto target proteins through binding to E2-conjugating enzymes, resulting in the induction of protein deubiquitination. OTUB1 can therefore canonically and non-canonically promote tumor cell proliferation, invasion, and drug resistance through regulating FOXM1, ERα, KRAS, p53, and mTORC1. Moreover, clinical research has demonstrated that OTUB1 overexpresses with high metastasis in many tumor types including breast, ovarian, esophageal squamous, and glioma. Therefore, OTUB1 has been suggested as a diagnosis marker and potential therapeutic target for oncotherapy.

A Study on the Characteristics of Daesoon Thought as Seen through the Articles in The Canonical Scripture: Focusing on Historical Figures (『전경(典經)』의 기사(記事)를 통해 살펴본 대순사상의 특징에 관한 연구 - 『전경』 속 인물을 중심으로 -)

  • Park Geon-woo
    • Journal of the Daesoon Academy of Sciences
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    • v.47
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    • pp.105-138
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    • 2023
  • The purpose of this study is to examine the significance of various figures in The Canonical Scripture and their contents. The Canonical Scripture (jeon-gyeong 典經) is a record of the beliefs and deeds of Kang Jeungsan, composed through the memories of the followers of Kang Jeungsan who followed the words of The Canonical Scripture. In other words, The Canonical Scripture is understood as the scripture of Daesoon Jinrihoe that contains the religious deeds and teachings of Kang Jeungsan. It is divided into seven parts and 17 chapters. Those seven parts, some of which contain more than one chapter, are as follows: Acts, Reordering Works, Progress of the Order, Dharma, Authority and Foreknowledge, Saving Lives, and Prophetic Elucidations. In particular, The Canonical Scripture records the deeds of historical figures from both China and Korea, and this prominently includes the life history of Kang Jeungsan, and this is an especially pronounced feature of the sections Acts, Progress of the Order, and Prophetic Elucidations. In addition, each chapter describes the teachings and faith-inspiring acts of Kang Jeungsan and presents the gist of the Daesoon Thought while referring to the lives and actions of various historical figures. In this paper, introductions to the figures that appear in each section are provided to help readers better understand the contents of The Canonical Scripture. Therefore, this study focuses on the major figures introduced in The Canonical Scripture in connection with the religious values of Daesoon Thought. Through this, a contribution is made to the academic development of Daesoon Thought by specifically exploring and examining the contents of the figures who appear in The Canonical Scripture. This is a surprisingly underdeveloped area of study in Daesoon Thought.