• Proceedings of the Korean Society of Crop Science Conference
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• 2007.11a
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• pp.235.1-235.1
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• 2007

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.3 s.31
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• pp.34-54
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• 2006

The effects of four extracts of medicinal herbs, Rubus coreanum, Acorus calamus, Morus alba and Rehmannia glutinosa on hair growth activity and acnes control were investigated. In the course of screening natural extracts for hair growth, we found that the extract of dried root of Rubus coreanum has the hair growth promoting effect. After topical application of these extracts to the back of C57BL/6 mice, the earlier conversion of telogen-to-anagen phase was induced. The growth of dermal papilla cells and mouse vibrissae hair follicle cultured in vitro, however, was not affected by treatment of these extracts. Furthermore these extracts do not possesspotent inhibitory effect on $5{\alpha}-reductase$ I and II activity and anti-bacterial effect on Escherichia coli , Propionibacterium acnes, Pityrosporum ovale, Staphylococcus aureus, Staphylococcus epidemidis, and Candida albicans. RT-PCR analysis showed that these extracts did notinduce mRNA levels of growth factors such as insulin-like growth factor-I, keratinocyte growth factor, hepatocyte growth factor and vascular endothelial growth factor in dermal papilla cells. These results suggest that Rubus coreanum has hair growth promoting effect. However, the effects of these materials on the hair growth promotion are not mediated through inhibition of $5{\alpha}-reductase$ I and II activity, stimulation of hair follicle cells and expression of growth factors in the dermal papilla cells.

• Journal of Applied Biological Chemistry
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• v.44 no.1
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• pp.23-26
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• 2001

The insecticidal activities of 30 aromatic plant extracts against four insect pests were examined by direct contact application. Against Nilaparvata lugens female adults, Myzus persicae female adults, and Plutella xylostella larvae, at 5,000 ppm, >90% mortality was achieved in the methanol extracts of the rhizomes from Cnidium officinale, Acorus gramineus, Acorus calamus var. angustatus and Curcuma Ionga, the whole plant from Agastache rugosa, the fruits from Illicium verum and Piper nigrum, and the flower bud from Eugenia caryophyllata as well as Cinnamomum camphora steam distillate. Against Spodoptera litura larvae, all test plant extracts were ineffective. The plants described merit further study as potential insect-control agents against insect pests.

• Journal of Pharmaceutical Investigation
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• v.14 no.4
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• pp.178-182
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• 1984

Extract of drugs in commerce was administered to mice for 3 days and 7 days and its antifatigue effects were compared with those of P. ginseng extract and A. sessiliflorum extract. Mice were used for these experiments divided into ethyl alcohol and water extract of R. glutinosa(saengjihwang), R. glutinosa (sookjihwang), A. japonica(changchool), A. japonica(baekchool), P. officinale, C. japonica, C. morifolium, A. calamus were given ordinary dose rally. For antifatigue test, swimming performance were determined after the extract administration. The group of P. officinale gave high improvement of the swimming performance in ethyl alcohol extract group.

• Microbiology and Biotechnology Letters
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• v.21 no.2
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• pp.187-191
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• 1993

In order to find out an anticariogenic substance, antibacterial activities of some medical herbs and spices against Streptococcus mutans were investigated. The essential oils of oregano, thyme, sage, fennel, nutmeg, rosemary, calamus and cassia cortex were shown antibacterial effect against S. mutans. The essential oil of oregano among other tested medical herbs and spices showed the most active antimicrobial activity. The essential oil of oregano inhibited the activity of glucosyltransferase from S. mutans. The minimal inhibition concentration of oregano essential oil was determined as 0.05nl/ml. The activity of glucosyltransferase from S. mutans was inhibited in the presence of oregano essential oil.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.419-427
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• 2013

The insecticidal activity of 124 plant essential oils and control efficacy of six experimental spray formulations (SF) containing 0.25, 0.5, 1, 2.5, 5, and 10% of the selected oils was examined against both nymph and adult of the citrus flatid planthopper, Metcalfa pruinosa using direct contact applications (leaf dipping and spray). Reponses varied according to dose (1,000 and 500 mg/L). When exposed at 1,000 mg/L for 24 h using leaf dipping assay, 19 essential oils showed strong mortality (100%) among 124 essential oils screened. At 500 mg/L, 100% mortality was observed in cinnamon technical, cinnamon green leaf, cinnamon #500, cassia tree, citronella java and pennyroyal followed by origanum, thyme white, grapefruit, savory, fennel sweet, aniseed and cinnamon bark showed considerable mortality (93.3-80%) against nymphs of M. pruinosa. The moderate mortality (73.3-60%) was found in thyme red, tagetes, calamus, lemoneucalptus and geranium. Oils applied as SF-10% sprays provided 100 % mortality against adult M. pruinosa. One hundred mortalities were achieved in cinnamon technical at >SF-0.5 formulation, in cinnamon #500, cinnamon green leaf and penny royal at >SF-2.5. To reduce the level of highly toxic synthetic insecticides in the agricultural environment, the active essential oils as potential larvicides could be provided as an alternative to control M. pruinosa populations.

• Journal of Life Science
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• v.28 no.9
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• pp.1022-1029
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• 2018

This study was carried out to search for the anti-inflammatory activities of ethanol extracts obtained from 5 kinds of oriental medical plant; Pleuropterus multiflorus extract (PME), Acorus calamus L. extract (ACE), Lithospermum erythrorhizon Siebold & Zucc. extract (LEE), Xanthium strumarium L. extract (XSE), Lonicera japonica extract (LJE), which have traditionally been used as a drug in oriental medical plants in Korea. XSE showed cytotoxicity at 100, $200{\mu}g/ml$ concentration in RAW264.7 cells (p<0.05) and ACE showed cytotoxicity at $200{\mu}g/ml$ concentration in RAW264.7 cells (p<0.05). But other oriental medical plants did not showed cytotoxicity was observed in RAW264.7 cells below $200{\mu}g/ml$ concentration. These extracts at non-toxic concentrations showed anti-inflammatory effects. PME, ACE, XSE and LJE showed a concentration-dependent inhibitory effect on NO production and $PGE_2$ production in LPS-induced RAW264.7 cells. In particular, XSE showed the highest NO production inhibition ($52.9{\mu}g/ml$, $IC_{50}$) as well as the highest $PGE_2$ production inhibition at $50{\mu}g/ml$ (73.6%). ACE and LEE showed cell proliferation effects on HaCaT keratinocyte cells. Especially, LEE showed 21.1, 53.5 and 99.6% proliferative activity by incubation for 1, 3, 5days at $100{\mu}g/ml$ concentration. ACE also showed 11.2, 26.0% proliferative activity for 1day and 3days at $10{\mu}g/ml$ concentration. As a result of this study, ethanol extracts obtained from 5 kinds of oriental medical plant showed anti-inflammatory activity and HaCaT cell regeneration effect.

• Korean Journal of Environmental Biology
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• v.30 no.2
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• pp.107-120
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• 2012

This study was carried out to illiminate the diversity of vascular plants by making list of rheophyte and hydorphyte plants at Yugu stream. This study was conducted from Aug., 2009 to Sept. 2010 at 7 points. Based on the voucher specimens, vascular plants from investigated areas were 88 families 229 genera 290 species 3 subspecies 30 varieties 5 forms, totally 328 taxa. Korean endemic plants were 3 species such as Forsythia koreana (Rehder) Nakai (planted) and Paulownia coreana Uyeki (planted), and Weigela subsessilis (Nakai) L.H. Bailey. The rare and endangered plants were designated by Korea Forest Service were 4 taxa, such as Penthorum chinense Pursh, Acorus calamus L., Lilium callosum Siebold & Zucc. and Iris ensata var. spontanea (Makino) Nakai. Floristic special plants were totally 26 taxa, which were grade V of 2 taxa, grade IV of 2 taxa and grade III of 9 taxa. Naturalized plants were 27 taxa, that was 8.3% of whole discovered vascular plants in this area. Even naturalized plants has not influence on the vegetation of Yugu stream. Since village was composed along the stream and the roads and banks were linked, naturalized plants were flowed continuously into this region. So, strategy of the conservation for this region should be designed. Based on flora, 3 types of group were discriminated such as main stream type (4 points), branch stream type (2 points) and reservior type (1 point). Each group has difference in composition of plants.

• Korean Journal of Environmental Biology
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• v.36 no.4
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• pp.439-455
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• 2018

Hanon made in the largest maar crater in Korea, is the only paddy field ecosystem in Jeju Island that has been conducting rice farming, for the past 500 years. Flora surveys were conducted eight times, 2015-2018, to understand floristic characteristics and a restoration plan of the study area. As a result, vascular plants of Hanon paddy fields were listed 225 taxa that consist of 55 families, 151 genera, 194 species, 1 subspecies, 25 varieties, and 4 forms. The taxonomic group including the most species, was Gramineae (36 taxa). The next families were Compositae (29 taxa), Cyperaceae (20), Leguminosae (13), and Polygonaceae (11). Biological type of the Hanon was $Th-R_5-D_4-t$ type. The rare plants revealed 3 taxa; Ottelia alismoides(L.) Pers., Acorus calamus L., Pseudoraphis ukishiba Ohwi. Endemic plant revealed 1 taxon; Saururus chinensis(Lour.) Baill. Forty three taxa were naturalized plants composed of 15 families, 24 genera, 41 species, and 2 varieties. The urbanization index and naturalized index were 13.3% and 16.9%, respectively. The Hanon has high plant diversity, including endemic plant and rare plants, and is the only rice paddy in Jeju Island. So, the Hanon has sufficient values in ecological and socio-cultural aspects, so it should be maintained continuously in the future.

• The Korean Journal of Ecology
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• v.8 no.3
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• pp.171-176
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• 1985

The structure of natural vegetation and soil condition in bog area of Woopo, Changnyeung, South Korea were observed. The vegetations in the investigated area could be classified into two groups; a typical bog vegetation with dominant species of Eleocharis mamillats, Acorus calamus and Persicaria hostatosagittata and the transitional vegetation of three neighboring areas. Interspecific correlation in the investigated area was very close. In the typical bog vegetatiion regions (region II, III, V, VI, VII, VIII and X) soil pH, field moisture capacity, available P content and exchangeable K were moderate. But, In the transitiional area I, with the highest humus content, field moisture capacity and exchangeable K Salix gracilistyla was dominant. In the region IV with the lowest humus and a ailable P content and with high soil pH Geophyta was a major component species. Also Acorus region IX with the lowest content of exchangeable K Therophyta was dominant and plant species was diverse due to weak water influence. The vegetation structure of the region IX was most different from that of the whole vegetation.