• Title/Summary/Keyword: CS$_{2}$

Search Result 2,581, Processing Time 0.027 seconds

Effect of Safflower and Safflower Seed Extract on Osteogenic Differentiation of MC3T3E1 Cells (홍화, 홍화씨 추출물이 MC3T3E1 세포의 골분화 과정에 미치는 영향)

  • Yu, Sung-ryul;Shin, Seon-mi
    • The Journal of Internal Korean Medicine
    • /
    • v.36 no.4
    • /
    • pp.518-526
    • /
    • 2015
  • Objectives This study investigated the effect of purified safflower (Carthamus tinctorius Linne) and safflower seed (Carthamus tinctorius L. seed; CS) extract, using hot water and ethanol extract methods , on the osteogenic differentiation of MC3T3E1 cells.Methods The safflower and safflower seed were extracted with hot water and ethanol. The samples were concentrated by a rotary evaporator and then freeze-dried using a freeze-dryer. The MC3T3E1 cells were propagated and maintained in DMEM (Gibco) containing 10% FBS and a 1% antibiotic antimycotic solution. To induce osteogenic differentiation, the cells were treated for 14 days with DMEM with 10 mM β-glycerophosphate and 50 μM ascorbic acid. Extract doses were confirmed by the results of an MTT assay, and treatment of the extracts was performed in a differentiation medium every two days. The ALP staining and activity were tested after osteogenic differentiation for five days, and after 14 days, osteogenic differentiation was determined by alizarin red S staining. The mRNA expressions of osteogenic-related genes were quantified using quantitative real-time PCR.Results In the results of the MTT assay, all concentrations of safflower extracts had no toxicity in the MC3T3El cells. But in the groups of 100 ng/ml and 200 ng/ml concentrations of safflower seed extracts, the cell viability was significantly reduced by up to 40-50%. So we fixed the treatment concentration of the extract at 50 ng/ml. In the ALP and alizarin red S staining, all extract groups increased osteogenic differentiation compared with the control group. The water-safflower extract group showed the highest mRNA level of Alp, Runx2, and Dlx5 genes. The mRNA level of Ocn, an osteogenic gene related to late-stage differentiation, in the ethanol-safflower extract group increased the mineralization more significantly than in other groups.Conclusions These data suggest that the extract of safflower increases the osteoblastic differentiation activates of MC3T3E1 cells like the extract of safflower seed. The water-extract and ethanol-extract of safflower have effects on different stages of osteogenesis in MC3T3El. Not only safflower seed but also safflower will be useful therapeutic reagents for age-associated chronic diseases such as osteoporosis.

The Usefulness of a Wearable Smart Insole for Gait and Balance Analyses After Surgery for Adult Degenerative Scoliosis: Immediate and Delayed Effects (척추측만증 환자의 수술 효과 평가 수단으로서 웨어러블 스마트 깔창을 이용한 보행분석의 유용성)

  • Seo, Min Seok;Shin, Myung Jun;Kwon, Ae Ran;Park, Tae Sung;Nam, Kyoung Hyup
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.2
    • /
    • pp.184-192
    • /
    • 2020
  • This study presents a gait analysis method (including time series analysis) using a smart insole as an objective and quantitative evaluating method after lumbar scoliosis surgery. The participant is a degenerative lumbar scoliosis patient. She took 3-min-gait-test four times(before and 8, 16, and 204-days after surgery) and 6-min-gait-test once(204-days after surgery) with smart-insoles in her shoes. Each insole has 8-pressure sensors, an accelerometer, and a gyroscope. The measured values were used to compare the characteristics of gait before and after surgery. The analysis showed that all of the patient's gait parameters improved after surgery. And after 6 months, the gait was more stable. However, after long walk, the swing duration of one leg was slightly shorter than that of the other again. It was a preclinical problem that could not be found in the visual examination by the practitioner. With this analysis method we could evaluate the improvement of patient quantitatively and objectively. And we could find a preclinical problem. This analysis method will lead to the studies that define and distinguish gait patterns of certain diseases, helping to determine appropriate treatments.

Effects of Ego-Resilience, Family Function and Acculturative Stress on Mental Health of the Youth of Multicultural Families (다문화가정 청소년의 자아탄력성과 가족기능, 문화적응 스트레스가 정신건강에 미치는 영향)

  • Song, Soon-Taek;Choi, Hee-Chul
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.2
    • /
    • pp.116-125
    • /
    • 2020
  • This study examined the effect of ego-resilience, function of family, stress of adapting to a new culture perceived by youth from multi-cultural families at Gyeonggi-do on their mental health. In doing so, the study sought to suggest effective supportive visits to enhance their mental health. For this, the study carried out a descriptive analysis, t-test, one-way anova, hierarchical regression analysis among 304 middle schoolers from multi-cultural families living at Gyeonggi-do. The study found following results. The higher youth from multi-cultural family perceived the procedural stress, sub-variable of stress of adapting to a new culture and the lower they perceived emotional control, sub-variable of ego-resilience, the higher depression and anxiety they experienced, resulting in worsening of their mental health state. Based on these findings, the study, in order to enhance the mental health of youth from multi-cultural family and their ego-resilience, discussed and suggested development of psychological/emotional programs, preparation of supportive measures to overcome their stress in the course of their cultural adaptation as well as systematic supplementation of related laws in support of multi-cultural families.

Relationship between Interpersonal Relationship Ability, Interpersonal Relationship Satisfaction, Stress and Department Satisfaction of Dental Hygiene Students (일부 치위생과 학생들의 대인관계 능력, 대인관계 만족도 및 스트레스와 학과만족도와의 관련성)

  • Choi, Mi-Hyun;Lee, Hye-Jin
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.2
    • /
    • pp.160-166
    • /
    • 2020
  • The purpose of this study was to identify dental hygiene students' interpersonal relationship ability, interpersonal relationship satisfaction, stress levels and to develop positive measures for adapting to university life through the investigation of their relevance to the departmental satisfaction. It was conducted by using the convenience sampling of students enrolled in the dental hygiene department and a self-reported survey. Collected data were analyzing by using SPSS Statistics version 22.0 program (p=0.05). The correlations among their interpersonal relationship ability, interpersonal relationship satisfaction, stress and department satisfaction were examined to show that interpersonal relationship ability have a positive correlation with department satisfaction, while stress has a negative correlation with the latter. Both department intelligibility and interpersonal relationship ability, as factors influencing their department satisfaction, have positive effects on department satisfaction, indicating that the factors influencing that the factors influencing dental hygiene students' department satisfaction are interpersonal relationship ability and department intelligibility. Although this study is limited to generalization by conducting research on some dental hygiene students, it is deemed necessary to develop and apply interpersonal relationship ability and department-related information programs as a way to increase department satisfaction.

Analysis regarding Complaints of Courier Consumers and Workers in the Parcel Delivery Service by using Topic Model (토픽모델을 활용한 택배 서비스 소비자와 종사자의 불만 사항 분석)

  • Shin, Jin Gyu
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.2
    • /
    • pp.39-48
    • /
    • 2020
  • Many studies have been conducted to analyze factors that affect customer satisfaction, and service quality improvement in the parcel delivery industry. Most of these studies have a limited number of respondents using methods such as surveys and interviews. Therefore, this study aims to supplement the shortcomings of previous studies, by searching and analyzing the common major topics related to the complaints pointed out by consumers and suppliers in the parcel delivery service with cases of consumer counseling, and articles that reflect the complaints of workers in the industry. In addition, by analyzing the trend of these topics, we attempted to discover new topics and suggest implications. In conclusion, topics such as delay/lost/wrong deliveries as well as the fierce competition in the parcel delivery industry, turned out to be central aspects. As a result of the topic trend analysis, talks with international couriers have recently increased, and many conflicts related to apartment parcel delivery have been dealt with. The topics presented in this study are mainly focused on the contents of previous studies, but we expect that new and valuable topics can be derived by adding other data and analysis methods, such as internal counseling and academic literature.

The Effect of Consumer's Interpersonal Anxiety on Shopping Addiction: Focusing on Multi-parallel Mediation Effect of Self-Control and Public-Consciousness and Moderating Effect between Men and Women (소비자의 대인 불안이 구매중독 성향에 미치는 영향: 자기 통제력과 타인 의식성의 다중 병렬매개효과와 남녀 간의 조절 효과를 중심으로)

  • Park, Ok-Hee;Jeong, Jo-Hee;Lee, Seok-Kee
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.2
    • /
    • pp.70-81
    • /
    • 2020
  • Living in the modern world, we can easily access large marts and outlets, and live convenient mobile shopping and same-day and early morning shipping. It is called 'shopping addiction' when the purpose of such shopping is not to be attributed to the original purpose of the goods, but to be purchased by an irresistible impulse. According to past studies, 5.8% of American adults and 15.5% of Korean college students were found to be purchase poisoning[3]. The study identified the relationship between interpersonal anxiety, public-consciousness and self-control among the various factors leading to purchase addiction and confirmed their impact on consumers internal psychology. The study found that although Interpersonal anxiety did not directly affect purchasing addiction, it was influenced by self-control and public-consciousness that increased the tendency to purchase addiction. The results of the group comparison between men and women showed that the self-control of men and the public-consciousness of women has increased their purchasing addiction. Such differences in psychology between men and women suggested related implications, such as the need to apply purchase addiction prevention management and treatment methods differently.

Development of Personal Information Protection Framework to be Followed by IoT Service Providers (IoT서비스제공자가 준수해야 할 개인정보보호 프레임워크의 개발 방안)

  • Shin, Young-Jin
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.7
    • /
    • pp.20-32
    • /
    • 2020
  • This study is to develop and provide a personal information protection framework that enables IoT service providers to safely and systematically operate personal information of IoT service subjects in the overall process of providing IoT devices and services. To this end, a framework for personal information framework was derived through literature survey, and FGI with experts, it was divided into three stages, each of three stages: IoT service provision process and IoT personal information processing process. The study conducted an e-mail survey of related experts using AHP techniques to determine the importance of the components of the selected personal information protection framework. As a result, in the IoT service provision process, the IoT product and service design and development stage (0.5413) is the most important, and in the IoT personal information processing process, personal information protection in the collection and retention of personal information (0.5098) is the most important. Therefore, based on this research, as the IoT service is spreading, it is expected that a safe personal information protection framework will be realized by preventing security threats and personal information infringement accidents.

Health behaviors and quality of life by life cycle of hypertensive patients (고혈압환자의 생애주기별 건강행태와 삶의 질)

  • Kim, Hyun-Ji;Min, Eun-Sil
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.7
    • /
    • pp.58-66
    • /
    • 2020
  • The purpose of this study was to identify the relation of health behaviors and the quality of life by life cycle of hypertensive patients. This study was conducted by analyzing secondary data with data from the 2017 Community Health Survey. The subjects were total of 62,056 who were diagnosed with hypertension and analyzed using the SPSS WIN 20.0 program. As a result of the study, As a result of the study, first, hypertension treatment and drug compliance were significantly lower in adulthood than in middle-aged and older adults. Second, it was confirmed that the quality of life score by life cycle was the highest in adulthood and decreased as age increased. Third, the quality of life according to health behaviors differed according to drinking, exercise, and low-salt diet throughout the life cycle. Considering the results presented in this study, it is suggested that health education by life cycle is essential for lifelong health management of hypertensive patients. In particular, it is considered that a convergence approach such as education and medical approaches will be needed to develop measures to increase drug compliance in adult hypertensive patients and to have healthy health behaviors to improve quality of life.

Development and Effectiveness Verification of CBT and ACT Group Counseling Programs for Maladjusted Soldiers (부적응 병사를 위한 인지행동치료 및 수용전념치료 집단상담 프로그램 개발 및 효과 검증)

  • Cho, Ju Sung;Choi, Jaegwang;Kang, Yohan;Yu, Han Byeol;Song, Wonyoung
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.11
    • /
    • pp.224-231
    • /
    • 2020
  • This study was conducted to develop a group counseling program to solve the problem of maladjustment of military personnel and to verify the effectiveness of the program. The 12 session CBT and ACT program for military soldiers experiencing emotional and behavioral problems was developed and the effectiveness was verified by conducting a program once a week for soldiers in the army units based in South Chungcheong Province. Adult Self Report scale(ASR) was implemented for pre-post test and analysis, and descriptive statistical analysis, cross-analysis, paired sample t-test, and independent sample t-test were performed to analyze the results. The results indicated are as follows: First, the preliminary homogeneity test between groups showed that the two groups had homogeneous demographic characteristics and the characteristics of the variables. Second, as a result of the pre-post test verification, both CBT and ACT groups showed significant changes in problem behavior totals, internalizations, and externalizations. Third, there was no difference between the pre-post-examination of the CBT group and the ACT group. This study is meaningful in that it was involved in the maladjustment problem within the military unit, and compared the effectiveness between the two theories, and proposed the study of control groups and further studies on more diverse and diverse subjects that were not implemented under the circumstances of the unit.

The Study on the Satisfaction Factors of the Support Projects for the Adjacent Residents to Multipurpose Dams (다목적 댐주변지역지원사업 고객만족에 미치는 영향 요인 연구)

  • Kim, Shang Moon;Lee, Byungchul
    • Journal of Korea Water Resources Association
    • /
    • v.46 no.4
    • /
    • pp.335-343
    • /
    • 2013
  • Multi-purpose dams are regarded to contribute to the Korean society not only positive affects but also negative ones. Especially, negative considerations are usually prevailed around multi-purpose dam sites and their vicinities even though the Government adopted "act on dam construction and assistance, etc. to neighborhood area" in 1989 and has supported many various projects since 1990. Nevertheless, many arguments and controversies about effects of multi-purpose dams and support projects to vicinities" have happened so frequently and sometimes brought a suit against government. These situations imply that support projects are not so sufficient to fulfil peoples' expectations. Therefore, this research figured out the key factors that affected residents' satisfaction about multi-purpose dams and support projects. The results of the research are as follows: 1) 'social necessity of dams', 'rationality of the process in supporting project' and 'appropriateness of supporting project', were statistically significant to 'customer satisfaction'; 2) among these factors, 'rationality of the process in supporting project' was the most related to 'customer satisfaction': 3) 'appropriateness of supporting project', 'social necessity of dams' were also revealed as second third factors that relate to the satisfaction.