• Title/Summary/Keyword: COVID-19(Coronavirus)

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The Effect of the Self-reflection Promotion Program in Non-face-to-face Video Classes due to COVID-19

  • Park, Jung-Ha
    • International Journal of Advanced Culture Technology
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    • v.9 no.4
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    • pp.188-193
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    • 2021
  • This is a group pretest-posttest design study that aim to evaluate the effect of self-reflection promotion program of nursing students. The subjects of this study were 42 first-year nursing students. The data was collected from October 5 to November 2, 2020. A questionnaire was used to measure self-reflection and self-efficacy. The self-reflection promotion program was operated for a total of 8 hours in 4 sessions over 4 weeks. Online lectures were conducted using books, movies, and art recommended by expert. The subjects could take lectures using their smartphones, laptops, desktops, and tablet PC. As a result of the study, self-reflection was significantly improved after intervention than before intervention (t=-2.594, p=.013). In the sub-items, self-exploration and self-understanding were statistically significantly improved (t=-2.527, p=.015; t=-2.471, p=.018). However, other-exploration and other-understanding were not statistically significant (t=-1.226, p=.227; t=-.758, p=.453). The self-efficacy of the subjects was not statistically significant (t=-.170, p=.866). In future research, it will be necessary to develop and verify specific teaching and learning methods utilizing various contents that can improve self-reflection for nursing students.

Genomic epidemiology and surveillance of zoonotic viruses using targeted next-generation sequencing (표적화 차세대염기서열분석법을 이용한 인수공통 바이러스의 유전체 역학과 예찰)

  • Seonghyeon Lee;Seung-Hwan Baek;Shivani Rajoriya;Sara Puspareni;Won-Keun Kim
    • Korean Journal of Veterinary Service
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    • v.46 no.1
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    • pp.93-106
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    • 2023
  • Emerging and re-emerging zoonotic viruses become critical public health, economic, societal, and cultural burdens. The Coronavirus disease-19 (COVID-19) pandemic reveals needs for effective preparedness and responsiveness against the emergence of variants and the next virus outbreak. The targeted next-generation sequencing (NGS) significantly contributes to the acquisition of viral genome sequences directly from clinical specimens. Using this advanced NGS technology, the genomic epidemiology and surveillance play a critical role in identifying of infectious source and origin, tracking of transmission chains and virus evolution, and characterizing the virulence and developing of vaccines during the outbreak. In this review, we highlight the platforms and preparation of targeted NGS for the viral genomics. We also demonstrate the application of this strategy to take advantage of the responsiveness and prevention of emerging zoonotic viruses. This article provides broad and deep insights into the preparedness and responsiveness for the next zoonotic virus outbreak.

The Effect of An Online Matching and Logistics System on Reverse Overseas Direct Purchase: The Mediating Effect of Reliability (온라인 매칭 및 물류시스템이 역직구 활성화에 미치는 영향-국가신뢰의 매개 효과)

  • Ju-Choel Choi;Cheol-Hong Min
    • Korea Trade Review
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    • v.45 no.3
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    • pp.1-19
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    • 2020
  • Recently, traditional trade in the global trade market has stagnated in the aftermath of the US-China trade war and the coronavirus (COVID-19) pandemic. However, the global e-commerce market is growing rapidly, presenting a new opportunity for exports. To examine the effect of an online matching and logistics system on reverse overseas direct purchase and the mediating effect of reliability, this study conducted a questionnaire survey on 320 employees in a Korean trade company from March 10 to April 30, 2018. The study model's goodness of fit was tested, and an analysis was performed using the AMOS statistical package. The online matching and logistics system were found to have a positive effect on reverse overseas direct purchase. Furthermore, results revealed that while a country's reliability mediated online matching and reverse overseas direct purchase, it did not mediate the logistics system. These results mean that online matching is affected by a country's reliability in overseas consumers' buying decision process. This study provides implications for the future directions of export companies and national policies to promote reverse overseas direct purchase. Future research including more countries and companies would be able to make further contributions toward the development of the Korean cross-border e-commerce industry.

Postoperative conditions of rehabilitative interest in lung transplantation: a systematic review

  • Massimiliano Polastri;Esra Pehlivan;Robert M. Reed;Allaina Eden
    • Journal of Yeungnam Medical Science
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    • v.41 no.4
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    • pp.235-251
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    • 2024
  • Lung transplantation is an elective treatment option for end-stage respiratory diseases in which all medical therapy options have been exhausted. The current study aimed to identify updated information on the postoperative conditions that may impair rehabilitation after lung transplantation and to provide specific considerations of their clinical relevance during the recovery process. The present study is a systematic review conducted by searching three primary databases: the United States National Library of Medicine PubMed system, Scopus, and the Cochrane Library. The databases were searched for articles published from database inception until May 2024; at the end of the selection process, 27 documents were included in the final analysis. The retrieved material identified 19 conditions of rehabilitative interest that potentially affect the postoperative course: graft dysfunction, dysphagia, postsurgical pain, cognitive impairment, chronic lung allograft dysfunction-bronchiolitis obliterans syndrome, phrenic nerve injury, delayed extracorporeal membrane oxygenation weaning, airway clearance, refractory hypoxemia, mediastinitis, reduced oxidative capacity, sternal dehiscence, coronavirus disease 2019 (COVID-19), gastroparesis, ossification of the elbow, Takotsubo cardiomyopathy, airway dehiscence, recurrent pleural effusion, and scapular prolapse. Although some patients are not amenable to rehabilitation techniques, others can significantly improve with rehabilitation.

The Effect of Pan Play Counseling in the Midst of COVID-19 on the Reduction of Anxiety in College Students (COVID-19 상황에 판놀이 상담이 대학생의 불안 감소에 미치는 효과)

  • Kim, Kyung Hee
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.2
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    • pp.317-324
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    • 2021
  • The purpose of this study was to conduct pan play counseling that contains Korean cultural characteristics to see if it affects college students' anxiety reduction in coronavirus situations. Counseling was conducted for 40 minutes once a week. The associations of participants were recorded for each session. The score of anxiety test decreased in the participants' pre-and post-anxiety tests. The effectiveness of pan play counseling was verified. Case analysis applied phenomenological research method. Structural decisions through case analysis were in the order of regression, expression, differentiation, and integration. In the results of case analysis, participants feel confused through encounters in the early stages and regress unconsciously. Emotions of negativity that could not be erupted in the expression structure appear as consciousness, and the participants awaken. Participants expressed emotions such as fear, anxiety, loneliness, anger, and irritation. Consciousness of the unconscious causes a transformation of ego. The ego gains discernment as the great drama emerges from the differentiated structure. In other words, it builds confidence. The goal of counseling is to reinforce the ego, realizing the potential to overcome anxiety. In the last integration's structure, a wedding, a baby, and a old wise man appeared, showing that a transformation took place. In the results of this study, it was verified that pan play counseling has a healing effect. This study is expected to serve as an opportunity to develop Korean counseling techniques that incorporate Korean culture.

Face-to-face non-face-to-face convergence tea culture therapy program to alleviate anxiety of the elderly suffering from COVID-19 pandemic anxiety (코로나19 팬데믹 불안을 겪는 노인들의 불안감 완화를 위한 대면 비대면 융합 차문화치료 프로그램)

  • Kim, In-Sook
    • Journal of Internet of Things and Convergence
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    • v.7 no.3
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    • pp.31-37
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    • 2021
  • This study aims to develop a face-to-face & non-face-to-face convergence tea culture therapy program for elderly people experiencing CORONA 19 pandemic anxiety and digital alienation, and apply the program to eight senior citizens aged 70 or older who use the K Senior Citizens' Day Care Center in P City to verify its effectiveness. Anxiety among elderly people experiencing coronavirus anxiety was 3.02 (SD 0.25) before participating in the program and 2.79 (SD 0.15), indicating a significant difference between before and after participating in the program (Z=4.245, P=.004) Based on this analysis, we present practical suggestions for the expansion of face-to-face & non-face-to-face convergence tea culture therapy programs to alleviate anxiety among elderly people who experience CORONA 19 pandemic anxiety.

Analysis of Library User Needs in the New Normal Era: Focusing on Social Media (뉴노멀 시대의 도서관 이용자 요구 분석 - 소셜 미디어를 중심으로 -)

  • Park, Tae-Yeon;Oh, Hyo-Jung
    • Journal of Korean Library and Information Science Society
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    • v.52 no.2
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    • pp.303-330
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    • 2021
  • The coronavirus infection-19 (hereinafter referred to as Corona 19) that occurred last year has not been ended until now. There have also been major changes in the library environment. This study focuses on changes in the library environment due to prolonged infectious diseases. In addition, it aims to derive implications for library services in the New Normal era by analyzing changes in user needs over time. For this purpose, we have comprehensively summarized the response activities of libraries due to the spread of Corona 19 in 2020, and analyzed changes in user needs that appeared on social media. Key terms were selected by collecting 496,741 tweets related to libraries in 2019 and 2020, and analysis by year and period by operation type was conducted. Through the analysis, the needs of library users in 2020 were classified into four issues, and the implications for each issue were derived.

Comparative Study of Target Genes and Protocols by Country for Detection of SARS-CoV-2 based on Polymerase Chain Reaction (PCR) (중합효소 연쇄반응 기반의 코로나-19 바이러스 검출법에 대한 국가별 목표 유전자 및 프로토콜 비교 연구)

  • Kim, Jin-Hee
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.465-474
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    • 2021
  • Corona-19, a disease caused by 'Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)', was declared a global pandemic by the World Health Organization (WHO) in March 2020, and a real-time polymerase chain reaction test is performed as a diagnostic test for screening and confirmation in most countries. However, not only the target genes and protocols differ by countries, but also the procedures for reading the diagnosis results are diverse, so the criteria for confirmed patients differ by country. Therefore, in this review, we discussed the target genes, test techniques, and diagnostic criteria for each country notified by WHO. And the specificity and sensitivity, limits of detection, positive and negative controls, false positive bacteria candidates, and specimens, and the specifics of the control setting were also described. In addition, the characteristics of Korea's test were compared to each country's one. Finally, in order to obtain the same diagnosis result for SARS-CoV-2 in the future, standardized diagnosis methods and result interpretations for Corona-19 diagnosis were proposed.

The Classification System and Information Service for Establishing a National Collaborative R&D Strategy in Infectious Diseases: Focusing on the Classification Model for Overseas Coronavirus R&D Projects (국가 감염병 공동R&D전략 수립을 위한 분류체계 및 정보서비스에 대한 연구: 해외 코로나바이러스 R&D과제의 분류모델을 중심으로)

  • Lee, Doyeon;Lee, Jae-Seong;Jun, Seung-pyo;Kim, Keun-Hwan
    • Journal of Intelligence and Information Systems
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    • v.26 no.3
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    • pp.127-147
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    • 2020
  • The world is suffering from numerous human and economic losses due to the novel coronavirus infection (COVID-19). The Korean government established a strategy to overcome the national infectious disease crisis through research and development. It is difficult to find distinctive features and changes in a specific R&D field when using the existing technical classification or science and technology standard classification. Recently, a few studies have been conducted to establish a classification system to provide information about the investment research areas of infectious diseases in Korea through a comparative analysis of Korea government-funded research projects. However, these studies did not provide the necessary information for establishing cooperative research strategies among countries in the infectious diseases, which is required as an execution plan to achieve the goals of national health security and fostering new growth industries. Therefore, it is inevitable to study information services based on the classification system and classification model for establishing a national collaborative R&D strategy. Seven classification - Diagnosis_biomarker, Drug_discovery, Epidemiology, Evaluation_validation, Mechanism_signaling pathway, Prediction, and Vaccine_therapeutic antibody - systems were derived through reviewing infectious diseases-related national-funded research projects of South Korea. A classification system model was trained by combining Scopus data with a bidirectional RNN model. The classification performance of the final model secured robustness with an accuracy of over 90%. In order to conduct the empirical study, an infectious disease classification system was applied to the coronavirus-related research and development projects of major countries such as the STAR Metrics (National Institutes of Health) and NSF (National Science Foundation) of the United States(US), the CORDIS (Community Research & Development Information Service)of the European Union(EU), and the KAKEN (Database of Grants-in-Aid for Scientific Research) of Japan. It can be seen that the research and development trends of infectious diseases (coronavirus) in major countries are mostly concentrated in the prediction that deals with predicting success for clinical trials at the new drug development stage or predicting toxicity that causes side effects. The intriguing result is that for all of these nations, the portion of national investment in the vaccine_therapeutic antibody, which is recognized as an area of research and development aimed at the development of vaccines and treatments, was also very small (5.1%). It indirectly explained the reason of the poor development of vaccines and treatments. Based on the result of examining the investment status of coronavirus-related research projects through comparative analysis by country, it was found that the US and Japan are relatively evenly investing in all infectious diseases-related research areas, while Europe has relatively large investments in specific research areas such as diagnosis_biomarker. Moreover, the information on major coronavirus-related research organizations in major countries was provided by the classification system, thereby allowing establishing an international collaborative R&D projects.

Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2 by Targeting the Spike S2 Subunit

  • Kandeel, Mahmoud;Yamamoto, Mizuki;Tani, Hideki;Kobayashi, Ayako;Gohda, Jin;Kawaguchi, Yasushi;Park, Byoung Kwon;Kwon, Hyung-Joo;Inoue, Jun-ichiro;Alkattan, Abdallah
    • Biomolecules & Therapeutics
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    • v.29 no.3
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    • pp.282-289
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    • 2021
  • A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the basis for developing new antiviral drugs. The fusion core comprising the heptad repeat domains (HR1 and HR2) of SARS-CoV-2 spike (S) were used to design the peptides. A total of twelve peptides were generated, comprising a short or truncated 24-mer (peptide #1), a long 36-mer peptide (peptide #2), and ten peptide #2 analogs. In contrast to SARS-CoV, SARS-CoV-2 S-mediated cell-cell fusion cannot be inhibited with a minimal length, 24-mer peptide. Peptide #2 demonstrated potent inhibition of SARS-CoV-2 S-mediated cell-cell fusion at 1 µM concentration. Three peptide #2 analogs showed IC50 values in the low micromolar range (4.7-9.8 µM). Peptide #2 inhibited the SARS-CoV-2 pseudovirus assay at IC50=1.49 µM. Given their potent inhibition of viral activity and safety and lack of cytotoxicity, these peptides provide an attractive avenue for the development of new prophylactic and therapeutic agents against SARS-CoV-2.