• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.8
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• pp.741-757
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• 2016

Over 60 years has passed since mankinds started space exploration beyond the Earth with lunar explorer Luna 1 launched by Soviet Union. Unprecedently remarkable outcomes have been obtained by sending unmanned spacecrafts to most planets in the solar system and having the lander landed on the approaching comet toward the Earth even though any evidence of life presence has not been discovered yet. Only moon is an natural object beyond the earth on which human beings landed. Many countries are planning to send humans to the moon or mars to build colonies and to survive with substantiality. Korean lunar exploration program has officially started as of 2016 after its plan including lunar exploration has been specified in the series of National Space Promotion Plan since Korea initiated space development in early 1990s. In this paper, the plan for Korean space exploration is summarized with reviewing overseas space exploration program status and trends.

• Journal of Astronomy and Space Sciences
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• v.22 no.3
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• pp.293-310
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• 2005

We made a revised catalogue for reliable records of meteor outbursts that were recorded in Korean, Japanese, and Chinese chronicles. In order to avoid the effects of both Earth's precession and perihelion shift, we introduced a new time-coordinate of records, or the number of days elapsed within the sidereal year of the record for a given origin of time or the perihelion passage time of the you 2000. We added nineteen new records of meteor showers that are wrongly classified i, individual meteors in a Chinese archive. We found that the ${\eta}-Aquarids,$ the Perseids, the Orionids, and the Leonids have been active during the last two millennia. Due to the change of time-coordinate, the oldest record of each long-lasting meteor shower has been slightly corrected. We discuss that these long-lasting meteor showers belong to the Halley-type comets.

• Nutrition Research and Practice
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• v.3 no.2
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• pp.114-121
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• 2009

The effect of diet supplemented with red beet (Beta vulgaris L.) leaf on antioxidant status of plasma and tissue was investigated in C57BL/6J mice. The mice were randomly divided into two groups after one-week acclimation, and fed a high fat (20%) and high cholesterol (1%) diet without (control group) or with 8% freeze-dried red beet leaf (RBL group) for 4 weeks. In RBL mice, lipid peroxidation determined as 2-thiobarbituric acid-reactive substances (TBARS value) was significantly reduced in the plasma and selected organs (liver, heart, and kidney). Levels of antioxidants (glutathione and $\beta$-carotene) and the activities of antioxidant enzyme (glutathione peroxidase) in plasma and liver were considerably increased, suggesting that antioxidant defenses were improved by RBL diet. Comet parameters such as tail DNA (%), tail extent moment, olive tail moment and tail length were significantly reduced by 25.1%, 49.4%, 35.4%, and 23.7%, respectively, in plasma lymphocyte DNA of RBL mice compared with control mice, and indicated the increased resistance of lymphocyte DNA to oxidative damage. In addition, the RBL diet controlled body weight together with a significant reduction of fat pad (retroperitoneal, epididymal, inguinal fat, and total fat). Therefore, the present study suggested that the supplementation of 8% red beet leaf in high fat high cholesterol diet could prevent lipid peroxidation and improve antioxidant defense system in the plasma and tissue of C57BL/6J mice.

• Nutrition Research and Practice
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• v.5 no.6
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• pp.540-547
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• 2011

High consumption of fruits and vegetables has been suggested to provide some protection to smokers who are exposed to an increased risk of numerous cancers and other degenerative diseases. Carrot is the most important source of dietary ${\beta}$-carotene. Therefore, the objective of this study was to investigate whether carrot juice supplementation to smokers can protect against lymphocyte DNA damage and to compare the effect of supplementationof capsules containing purified ${\beta}$-carotene or a placebo (simple lactose). The study was conducted in a randomized and placebo-controlled design. After a depletion period of 14 days, 48 smokers were supplemented with either carrot juice (n = 18), purified ${\beta}$-carotene (n = 16) or placebo (n = 14). Each group was supplemented for 8 weeks with approximately 20.49 mg of ${\beta}$-carotene/day and 1.2 mg of vitamin C/day, as carrot juice (300 ml/day) or purified ${\beta}$-carotene (20.49 mg of ${\beta}$-carotene, 1 capsule/day). Lymphocyte DNA damage was determined using the COMET assay under alkaline conditions and damage was quantified by measuring tail moment (TM), tail length (TL), and% DNA in the tail. Lymphocyte DNA damage was significantly decreased in the carrot juice group in all three measurements. The group that received purified ${\beta}$-carotene also showed a significant decrease in lymphocyte DNA damage in all three measurements. However, no significant changes in DNA damage was observed for the placebo group except TM (P = 0.016). Erythrocyte antioxidant enzyme was not significantly changed after supplementation. Similarly plasma lipid profiles were not different after carrot juice, ${\beta}$-carotene and placebo supplementation. These results suggest that while the placebo group failed to show any protective effect, carrot juice containing beta-carotene or purified ${\beta}$-carotene itself had great antioxidative potential in preventing damage to lymphocyte DNA in smokers.

• Nutrition Research and Practice
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• v.5 no.5
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• pp.389-395
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• 2011

In the present study, a suitable drying method was developed for citrus press cakes (CPCs), which are produced as a by-product in citrus juice plants, and the protective effect of methanol extract of CPCs prepared by far-infrared radiation (FIR) drying against $H_2O_2$-induced DNA damage was evaluated versus that of freeze-dried CPCs. Methanol extract of FIR-dried CPCs exhibited comparatively good ROS scavenging activity versus the freeze-dried CPCs at the concentration of 100 ${\mu}g$/mL. The extract strongly enhanced the cell viability against $H_2O_2$-induced oxidative damage in Vero cells. Lipid peroxidation inhibitory activity of the extract from FIR-dried CPCs was comparable to that of the extract from freeze-dried CPCs. This sample also exhibited good protective effects against $H_2O_2$-mediated cell apoptosis as demonstrated by decreased apoptotic body formation in the nuclear staining with Hoechst 33342. In the comet assay, the CPC extracts exhibited strong inhibitory effects against $H_2O_2$-mediated DNA damage in a dose-dependent manner. Thus, this study demonstrated that FIR drying effectively preserves CPC as a functionally important natural antioxidant source and the FIR drying can be adapted for drying CPCs and is more economical for massive production than freeze drying.

• Journal of radiological science and technology
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• v.26 no.2
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• pp.49-56
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• 2003

The purposes of this study are to improve the ultrasound resolution of various nylon and metallic mono-filament wires, therefore, it was tested that it analyze on nylon mono-filament wire of 0.1 mm in A Co.'s ultrasonic phantom and synthesis of C15 g tissue mimicking materials(TMM), analyze resolution of nylon and metallic mono-filament wires in water and TMM. The results obtained were summarized as follows: 1. Metallic mono-filament wire of 0.1 mm and nylon mono-filament wire of 0.12 mm, 180 denier showed that it cleared dot echo pattern. 2. Metallic and nylon mono-filament wire of 0.2 mm showed that it cleared comet tail echo by reverberation artifact. 3. Nylon and metallic mono-filament wire of 0.1 mm showed that it can used for dead zone and axial resolution test. 4. Nylon mono-filament wire compared with metallic mono-filament wire showed that it satisfy elasticity and construction. 5. Degree of hardness of na not changed mono-filament's echo textures.

• Publications of The Korean Astronomical Society
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• v.14 no.1
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• pp.33-37
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• 1999

We have constructed a synthetic spectrum of the 2.5 micron $C_2H$ bands and compared them with diminutive structures in the near-infrared spectra of Comets P/Halley and West (1976 VI). We found that the Q branches of the $C_2H$ bands coincide with two small emission peaks in the spectra of the comets. We undertook Monte Carlo simulations using observed emission intensities of $C_2$ and possibly $C_2H$ in Comet P/Halley in order to derive a lifetime range of $C_2H$ and a production rate at the time of observations of P/Halley. We obtained a $C_2H$ production rate of $1\times10^{27}\;sec^{-1}$ for P/Halley on December 20, 1985, assuming the 2.5 micron features are due to $C_2H$. We derived a very short lifetime (<100 seconds) of $C_2H$ at 1AU heliocentric distance, assuming that the only parent molecule for $C_2H$ and $C_2$ is $C_2H$. Using this short lifetime we were unable to fit our $C_2$ distribution model to $C_2$ distribution curves observed by O'Dell et al.(1988), because our curve shows a steep slope compared with the observed one. We conclude that there must be significant additional source(s) for $C_2H$ and $C_2$ other than $C_2H_2$.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.48.3-49
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• 2016

We have five different types of observation modes with regard to the Deep Ecliptic Patrol of the Southern Sky (DEEP-South); Opposition Census (OC) for targeted photometry, Sweet Spot Survey (S1) for discovery and orbit characterization of Atens and Atiras, Ecliptic Survey (S2) for asteroid family studies and comet census, NEOWISE follow-up (NW) for near simultaneous albedo measurements in the visible bands, and Target of Opportunity (TO) observation for follow-up either for unpredictable events or targets of special interests. Different exposures with such different modes result in a wide range of background noise level, the number of background stars and the mover's projected speed in each image. The Moving Object Detection Program (MODP) utilizes multiple mosaic images being taken for the same target fields at different epochs at the three KMTNet sites. MODP employs existing software packages such as SExtractor (Source-Extractor) and SCAMP (Software for Calibrating Astrometry and Photometry); SExtractor generates object catalogs, while SCAMP conducts precision astrometric calibration, then MODP determines if a point source is moving. This package creates animated stamp images for visual inspection with MPC reports, the latter for checking whether an object is known or unknown. We evaluate the astrometric accuracy and efficiency of MODP using the year one dataset obtained from DEEP-South operations.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.2
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• pp.82.2-82.2
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• 2017

Korea Microlensing Telescope Network (KMTNet) is one of powerful tools for investigating primordial objects in the inner solar system in that it covers a large area of the sky ($2{\times}2$ degree2) with a high observational cadence. The Deep Ecliptic Patrol of the Southern sky (DEEP-South) survey has been scanning the southern sky using KMTNet for non-bulge time (45 full nights per year) [1] since 2015 for examining color, albedo, rotation, and shape of the solar system bodies. Since 2017 January, we have launched a new collaborative group between Korea Astronomy and Space Science Institute (KASI) and Seoul National University (SNU) with support from KASI to reinforce mutual collaboration among these institutes and further to enhance human resources development by utilizing the KMTNet/DEEP-South data. In particular, we focus on the detection of comets and asteroids spontaneously scanned in the DEEP-South for (1) investigating the secular changes in comet's activities and (2) analyzing precovery and recovery images of objects in the NASA's NEOWISE survey region. In this presentation, we will describe our scientific objectives and current status on using KMTNet data, which includes updating the accuracy of the world coordinate system (WCS) information, finding algorithm of solar system bodies in the image, and doing non-sidereal photometry.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.12
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• pp.6047-6053
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• 2012

Bracken fern [Pteridium aquilinem (L.) kuhn (Dennstaedtiaceae)] is one of the most common species on the planet. It has been consumed by humans and animals for centuries. Use by some human groups is because they believe bracken fern is good for health as plant medicine. However, it is also one of the few known plants that can cause tumors in farm animals. Many interested groups have focused their attention on bracken fern because of these interesting features. In order to evaluate the biological effects of exposure to this plant in cellular level, human cancer cell lines were treated with the fern dichloromethane extracts and the genotoxic and cytotoxic effects were studied. Anti-proliferative/cytotoxic effects were evaluated by cell count, MTT assay and flow cytometry methods with three different cancer cell lines, TCC, NTERA2, and MCF-7, and two normal cells, HDF1 and HFF3. Pro-apoptotic effects of the extracts were determined by DAPI staining and comet assay, on TCC cancer cells compared to the normal control cell lines. Cellular morphology was examined by light microscopy. Our present study showed that the extract caused DNA damage and apoptosis at high concentrations ($200{\mu}g/mL$) and also it may induce cell cycle arrest (G2/M phase) at mild concentrations (50 and $30{\mu}g/mL$) depending on the cell type and tumor origin. These results indicate that bracken fern extract is a potent source of anticancer compounds that could be utilized pharmaceutically.