• 제목/요약/키워드: CMT1A

검색결과 118건 처리시간 0.024초

이동 위성 통신 채널에서 다이버시티 수신기법을 적용한 BPSK 및 QPSK 신호의 오율 특성 (Error Performance of BPSK and QPSK Signals with Diversity Reception in Mobile-Satellite Communication Channel)

  • 박해천;강영흥;황인관;조성준
    • 한국전자파학회지:전자파기술
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    • 제5권3호
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    • pp.36-47
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    • 1994
  • 업링크와 다운링크 경로상에 각각 가산성 백색 가우스잡음이 존재하는 이동 위성 통신로에서 $\pi$1VTA의 비선 형성에 의한 BPSK신호와 QPSK선호의 오율성능을 조사하였다. 다운렁크 정로상의 페이딩은 Rician 분포를 한다고 가정하였다. 또한 선택적 다이버시티에 대한 효과를 분석하였다. 선택적 다이버시티의 확률빌도함수에 관한 N차 모멘트를 구하였으며, 선택적 다이버시타의 확률밀도함수에 대한 근사 이산 확률분포를 고전적인 모 멘트 기법 (CMT)을 이용하여 유도하였다. 오율은 Gauss Quadrature Formula와 근사 이산 확률 분포를 이용 하여 계산하였다.

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"Sandwich" Chemotherapy (CT) with Radiotherapy (RT) Improves Outcomes in Patients with Stage IE/IIE Extranodal Natural Killer (NK)/T-cell Lymphomas

  • Zhang, Jing;Zhu, Meng-Yuan;Wang, Liang;Wang, Hua;Wang, Wei-Da;Geng, Qi-Rong;Lu, Yue
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권7호
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    • pp.4061-4066
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    • 2013
  • The extranodal natural killer/T-cell lymphoma (ENKTL) shows high local or systemic failure rates when radiotherapy (RT) is taken as the primary treatment, suggesting a role for chemotherapy (CT) added to RT for this disease. However, the appropriate mode of combined modality therapy (CMT) has not been fully defined. A total of one hundred and twenty-one patients with ENKTL receiving sandwich CT with RT were reviewed between January 2003 and August 2012. The primary endpoints were the response rate, progression-free survival (PFS), overall survival (OS), and the relapse rate. After the initial CT, there were 84 (69.4%) patients in CR, 22 (18.2%) patients in PR, 9 (7.4%) patients in SD, and 6 (5%) patients in PD, respectively. At the end of RT, the CR, PR, SD, and PD rates for all patients were 90.9% (n=110), 1.7% (n=2), 4.1% (n=5), and 3.3% (n=4), respectively. After a median follow-up of 42.3 months (3.5~112.3 months), the 5-year PFS was 74.7% (95% CI 70.4%~79.0%), and 5-year OS was 77.3% (95% CI 67.9%~86.7%). Disease progression was documented in 25 (20.7%) patients. The rates of systemic failure, local failure, and regional failure were 18.2%, 5.8%, 1.7%, respectively. Twenty death events (16.5%) were observed for the entire group of patients (18 deaths related to PD). Furthermore, CR to the initial CT and low Korean Prognostic Index (KPI) can independently predict long PFS and OS. The sandwich CMT achieved an excellent outcome for localized ENKTL with acceptable toxicity. We recommend it can be applied as the optimal choice for localized ENKTL.

Fluorescence Spectroscopy Studies on Micellization of Poloxamer 407 Solution

  • Lee, Ka-Young;Shin, Sang-Chul;Oh, In-Joon
    • Archives of Pharmacal Research
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    • 제26권8호
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    • pp.653-658
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    • 2003
  • It has been reported that at low temperature region, poloxamers existed as a monomer. Upon warming, an equilibrium between unimers and micelles was established, and finally micelle aggregates were formed at higher temperature. In this study, the fluorescence spectroscopy was used to study the micelle formation of the poloxamer 407 in aqueous solution. The excitation and emission spectra of pyrene, a fluorescence probe, were measured as a function of the concentration of poloxamer 407 and temperature. A blue shift in the emission spectrum and a red shift in the excitation spectrum were observed as pyrene transferred from an aqueous to a hydrophobic micellar environment. From the $I_1/I_3 and I_{339}/I_{333}$ results, critical micelle concentration (cmc) and critical micelle temperature (cmt) were determined. Also, from the fluorescence spectra of the probe molecules such as 8-anilino-1-naphthalene sulfonic acid and 1-pyrenecarboxaldehyde, the blue shift of the $\lambda_{max}$ was observed. These results suggest a decrease in the polarity of the microenvironment around probe because of micelle formation. The poloxamer 407 above cmc strongly complexed with hydrophobic fluorescent probes and the binding constant of complex increased with increasing the hydrophobicity of the probe.

The Analysis of tight Coupling and Propagation for a Composite Fiber-Dielectric Slab with a Conductor Cladding

  • Kwon, Kwang-Hee;Song, Jae-Won;Kim, Jeong-Hoon;Park, Euy-Don;Son, Seok-Woo
    • Journal of the Optical Society of Korea
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    • 제7권1호
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    • pp.20-27
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    • 2003
  • A theoretical presentation of evanescent coupling is offered with respect to the refractive indexes between a side-polished optical fiber and an infinitely planar waveguide with a conductor cladding (PWGCC). The PWG is suspended at a constant distance from an unclad fiber core and attached with the perfect conductor (PEC) on one side. The behavior of the distributed couple. is examined using a coupled mode model, which takes account of the two dimensions of the waveguide configuration. The coupling and propagation of light were found to depend on both the relationship between the refractive index values of each structure and the configuration of the side-polished fiber used in the PWGCC. The spreading of light in the unconfined direction of the PWGCC is described in terms of a simple geometrical interpretation of the synchronization condition that is in agreement with a previous investigation of the problem based on the coupled-mode theory (CMT). The power of the light propagation in the fiber decreased exponentially along the fiber axis as it was transferred to the PWGCC, where it was carried away.

선천성 근성 사경의 임상적 특징 (Clinical features of congenital muscular torticollis)

  • 전지은;류혜경;심재원;심정연;정혜림;박문수;김덕수
    • Clinical and Experimental Pediatrics
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    • 제50권3호
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    • pp.241-247
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    • 2007
  • 목 적 : 선천성 근성 사경은 목빗근의 섬유화 변화로 인해 머리가 병변쪽으로 기울고 턱이 반대쪽으로 돌아가는 변형을 말하는 것으로 대개 생후 4주내에 발견되고 생후 수개월내에 소실되는 예후가 좋은 질환이다. 이와 관련된 국내 보고가 부족하나 비교적 흔한 근골격계 기형이기에 저자들은 연구를 시행하였다. 방 법 : 2003년 3월부터 2006년 5월까지 본원 소아과와 재활의학과에 사경을 주소로 내원한 환아 중 안과적 검사, 신경학적 진찰 및 정형외과적 진찰 소견에서 이상이 없는 선천성 근성 사경 환아 47명을 대상으로 하였다(남자 31명, 여자 16명). 임상적 특성으로 발견 당시의 연령, 진찰 소견, 초음파 검사, 치료 방법, 치료 기간, 치료 결과 등을 조사하였다. 결 과 : 진단 당시의 연령은 최소 18일에서 최고 9세 7개월로, 이들 연령의 중앙값은 90일이었고, 좌우측 발생 빈도는 우측이 26명, 좌측이 21명이었다. 진찰 소견상 경부 종괴가 만져지는 군은 24명으로 이 중 21명에서 초음파가 시행되었고 19명에서 초음파상 목빗근의 종괴가 관찰되었다. 진찰 소견상 정상적이었던 환아는 22명으로 이 중 11명에서 초음파가 시행되었으며, 3명에서 초음파상 목빗근의 종괴가 관찰되었다. 진단 당시 가장 나이가 많았던 환아는 수술로서 회복되었고, 그 외의 환아들은 모두 집이나 병원에서 수동적인 신연 운동을 받았다. 총 47명의 환아 중 7명이 추적관찰에서 누락되었고, 추적 관찰된 40명 중 36명은 완전한 회복을 보였다. 환아들의 진단 당시 연령과 회복 기간은 음의 상관관계를 가졌고, 초음파 소견에 따라 분류하였을 때 자세군에서는 85.7%, 종괴군에서는 90.0%, 근성군에서는 66.6 %의 완전한 회복을 보였다. 회복 기간은 자세군은 1개월, 종괴군은 2.4개월, 근성군은 7.5개월로 자세군에서 회복 기간이 가장 짧았다(P=0.0011). 결 론 : 초음파에서 목빗근의 이상 소견을 보였던 환아에서 더 느리게 호전되는 양상을 보이고 초음파 소견에 따라 서로 다른 치료 효과를 보였기에, 치료 효과와 기간을 예측하는데 초음파 소견이 도움이 될 것으로 생각된다.

맞대기 용접 시편의 백플레이트에 따른 피로강도 평가 (Fatigue Assessment in accordance with Back Plate of Butt Welded Specimens)

  • 도현덕;강성원;한주호;김성민;김명현
    • 대한조선학회논문집
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    • 제46권1호
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    • pp.24-30
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    • 2009
  • The purpose of this study is to investigate the fatigue strength in accordance with back plate of butt welded specimens. Fatigue life of butt welded specimens was presented for determining the effect of back plates in terms of fatigue strength. As a results, fatigue strength of butt welded specimens with steel back plate show a decrease as compared against the butt welded specimens with ceramic back plate. Compared with the fatigue strength with respect to the existence of steel back plate, the specimens without back plate were much higher than the specimens with back plate.

기억전략 프로그램이 정상 노인의 기억력에 미치는 효과 (The Effect of Memorial Strategy Program on Memory in the Elderly)

  • 이춘엽;류승민;김승환;공도현;이대은;이지호;정혜림
    • 대한지역사회작업치료학회지
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    • 제6권1호
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    • pp.33-39
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    • 2016
  • 목적 : 본 연구는 일반적으로 노인에게 저하되어 있는 기억력을 회복하거나 유지하기 위한 인지재활의 필요성을 인식하고 기억전략 프로그램이 정상 노인의 기억력에 미치는 효과를 알아보고자 하였다. 연구방법 : 부산광역시에 위치한 노인복지관을 이용하는 60세 이상의 노인 20명 중 무작위로 실험군과 대조군을 나누어 대조군은 기존 노인복지관 프로그램을 이용하였고, 실험군은 기억전략 프로그램을 주 2회, 4주간, 총 8회기 동안 실시하였다. 평가 전 후의 비교는 상황기억검사(Contextural Memory Test; CMT)를 시행하였다. 결과 : 두 집단의 프로그램 전과 후를 비교한 결과 두 집단 모두 순간기억과 지연기억에서 유의한 차이를 보이지 않았다(p>.05). 그러나 프로그램 후 실험군의 순간기억과 지연기억에서 모두 유의한 차이가 나타났다(p<.05). 결론 : 연구결과 기억전략 프로그램은 정상 노인에게 기억력을 증진시킬 수 있다는 것을 보여주었다. 앞으로 정상 노인을 위한 기억 증진 목적의 프로그램이 많이 개발되고 발전된다면 이후 발생하게 될 치매 혹은 경도인지장애의 발병을 예방해 줄 수 있을 것으로 기대된다.

기판온도에 따른 ITO 박막의 제조 및 특성 (Preparation and characterization of ITO Thin Film By Various Substrate heating temperature)

  • 김성진;박헌균
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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    • pp.94.2-94.2
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    • 2010
  • Indium tin oxide (ITO) Thin films were grown on Non-alkarai glass Substrates by PVD method and Subsequently Subjected to ($100^{\circ}C-350^{\circ}C$) Thermal Annealing (TA) In Nitr Oxygen ambinent. Most of all, The effect of TA treatment on the structural properties were studied by using X-Ray diffraction and atomic force microscopy, while optical properties were studied by UV-Transmittance measurements. After TA treatment, the XRD spectra have shown an effective relaxation of the residual compressive stress, As a result, XRD peaks increase of the intensity and narrowing of full width at half-maximun (FWHM). In addtion The microstructure, The surface morphology, the optical transmittance changed and improved, and we investigated The effects of temperature, Time and atmosphere during the TA on the structural and electrical properties of the ITO/glass on TA at $300^{\circ}C$. As a results, the films are highly transparent (80%~89%) in visible region. AFM analysis shows that the films are very smooth with root mean square surface roughness 0.58nm -2.75nm thickness film. It is observed that resistivity of the films drcreases T0 $1.05{\times}10^{-4}{\Omega}cmt$ $6.06{\times}10^{-4}{\Omega}cm$, while mobility increases from $152cm^2/vs$ to $275cm^2/vs$.

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Bus-waveguide-width Dependence of Evanescent Wave Coupling in a Microring Resonator

  • Son, Seong-Jin;Kim, Suyeon;Yu, Nan Ei;Ko, Do-Kyeong
    • Current Optics and Photonics
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    • 제5권5호
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    • pp.538-543
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    • 2021
  • The evanescent wave coupling of a microring resonator is controlled by changing the gap distance between the bus waveguide and the microring waveguide. However, the interdependence of the bus waveguide's width and the coupling is not well understood. In this paper, we investigate the dependence of coupling strength on the bus waveguide's width. The strength of the evanescent wave coupling is analytically calculated using coupled-mode theory (CMT) and numerically calculated by three-dimensional finite-difference-time-domain (FDTD) simulation. The analytic and numerical simulation results show that the phase-matching condition in evanescent wave coupling does not provide maximum coupling strength, because both phase-matching and mode confinement influence the coupling. The analytic and simulation results for the evanescent coupling correspond to the experimental results. The optimized bus-waveguide width that provides maximum coupling strength results in intrinsic quality factors of up to 1.3 × 106. This study provides reliable guidance for the design of microring resonators, depending on various applications.

원발성 고혈압에 대한 추나요법의 효과 : 체계적 문헌 고찰 (Chuna Manual Therapy for Essential Hypertension : A Systematic Review)

  • 임경태;황의형;김병준;박인화;허인
    • 척추신경추나의학회지
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    • 제12권1호
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    • pp.29-42
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    • 2017
  • Objectives : To determine the evidence of effectiveness and safety of Chuna manual therapy(CMT) for essential hypertension Methods : We searched 11 electronic databases(Pubmed, Web of Science, EMBASE, Cochrane Library, CAJ, KISTI, KISS, NDSL, KMBASE, RISS, DBpia) and related 2 journals up to April 2017. We included randomized controlled trials(RCTs) of testing Chuna manual therapy for hypertension patients. Results : Twenty one RCTs were eligible in our inclusion criteria. The meta-analysis of eighteen studies showed positive results for the using Chuna manual therapy for essential hypertension. Conclusions : There is favorable evidence of Chuna manual therapy for treating essential hypertension with meta-analysis. However, our systematic review has limited evidence to support Chuna manual therapy for essential hypertension because of low quality of original articles and further well-designed RCTs should be encouraged.

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