• Animal cells and systems
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• v.10 no.1
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• pp.41-47
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• 2006

Development of the mammalian pre-implantation embryos has unique features, such as a slow and unsynchronized cell division, compaction, and eventual formation of blastocysts with inner cell mass and trophectoderm. In order to have a clue on molecular mechanisms that reside in mouse early development, we suppressed expression of early embryo-specific genes with RNAi and observed their development in vitro. We observed developmental defects in embryos microinjected with dsRNAs for Oct4 or Nanog among the tested genes. Careful examinations revealed that development of the most of the Oct4- or Nanog-suppressed embryos were arrested at the morula stage. These results suggest that the Oct4 and Nanog activities are also required for embryogenesis earlier than the blastocyst stage.

• Korean Institute of Interior Design Journal
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• v.16 no.3 s.62
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• pp.111-118
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• 2007

Using effective light, which is physical experiences by its control and manner of adaption, and make human to recognize the shape and give the meaning, so that approaching against perception experimental method which plays a role in basic clue, is regarded crucial highly among human sensory organ. this study consider the perception conception, its feature and necessity against eyes' adaption among human perception experimental experiences which has been discussed indifferently for inner space. Also, we looked over the problems among actual examples of inner spaces which should be considered as to adaption conception of human beings. Furthermore, this study aims at basic studying, which searching for enable to adapt in case of planning for inner space planning and distributing the quality evaluation by using effective light.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.545-550
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• 2004

The deterioration of a shunting locomotive was characterized for the lifetime assessment. The locomotive has been used for shunting works in steel making processes, and in this investigation, various types of technical evaluation methods for the locomotive parts were employed to assess the current deterioration status and to provide important clue for lifetime prediction. Unlike other rolling stocks in railway applications, the diesel shunting locomotive is composed of major components such as diesel engine, transmission, gear box, brake system, electronic devices, etc. In this paper, the degree of deterioration in a diesel engine and power transmission parts has been presented based on the analysis results.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.551-556
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• 2004

The deterioration of a shunting locomotive was characterized for the lifetime assessment. The locomotive has been used for shunting works in steel making processes, and in this investigation, various types of technical evaluation methods for the locomotive parts were employed to assess the current deterioration status and to provide important clue for lifetime prediction. Unlike other rolling stocks in railway applications, the diesel shunting locomotive is composed of major components such as diesel engine, transmission, gear box, brake system, electronic devices, etc., which cover more than 70 percent of the total price of the locomotive. Therefore, in this paper, each part of major components in the diesel locomotive was analyzed in terms of the degree of deterioration. The life-cycle-cost (LCC) analysis was performed based on the maintenance and repair history as compared with economical cost to provide the cost-effective prediction, i.e., to assess either repair for reuse or putting the locomotive out of service based on cost-effective calculation.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.557-562
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• 2004

The deterioration of a shunting locomotive was characterized for the lifetime assessment. The locomotive has been used for shunting works in steel making processes, and in this investigation, various types of technical evaluation methods for the locomotive parts were employed to assess the current deterioration status and to provide important clue for lifetime prediction. Unlike other rolling stocks in railway applications, the diesel shunting locomotive is composed of major components such as diesel engine, transmission, gear box, brake system, electronic devices, etc. In this paper, the analysis results of running performance assessment have been used to provide the critical information for the criteria of precision diagnosis assessment.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.56.1-56.1
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• 2014

With the advent of high-resolution high-sensitivity observations, spiral patterns have been revealed around several asymptotic giant branch (AGB) stars. Such patterns can provide possible evidence for the existence of central binary stars embedded in outflowing circumstellar envelopes. It is, however, not generally recognized that the binary induced pattern, vertically extended from the orbital plane, exhibits a ring-like pattern with an inclined viewing angle. I will first review the binary-induced spiral-shell patterns on the AGB circumstellar envelopes with the effect of inclination angle with respect to the orbital plane, of which large inclination cases reveal incomplete ring-like patterns. I will describe a method of extracting such spiral-shell from the gas kinematics of an incomplete ring-like pattern to place constraints on the characteristics of the (unknown) central binary stars. This first success may open the possibility of connecting the ring-like patterns commonly found in the AGB circumstellar envelopes and in the outer parts of (pre-)planetary nebulae and pointing to the conceivable presence of central binary systems, which may give a clue for the onset of asymmetrical planetary nebulae.

• Korean Institute of Interior Design Journal
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• no.27
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• pp.168-175
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• 2001

This study focuses to enhance the general understanding on the new approach and to provide a clue for a new paradigm in man-made physical and residential environment of the 21st Century. Through case analysis, this study aims to examine the characteristics of digital culture itself and of its physical and residential environment and to ultimately forecast the changeability of physical and residential environment prompted by the new digital wave. Without having precedent study about digital culture related to environmental issues, this study aimed to analyze the effect of digital culture in the field of physical environment and residential environment, and to forecast the changability in those fields. On the other hand, this study also atoned to be applicable in construction of a new paradigm in designing physical & residential environment in the near future, so as to contribute to the development of a new environment which will eventually improve the quality of human life.

• Biomedical Science Letters
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• v.18 no.1
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• pp.71-75
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• 2012

The PLA2G4A catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid, which is metabolized into lipid-based cellular hormones that regulate inflammatory response. The circulating blood cell numbers can be influenced by stress, infection or inflammation. Quantitative blood cell count traits analysis for the 19 SNPs in the PLA2G4A gene in the Korean Association Resource (KARE) cohort (7551 subjects) was performed. The only one SNP (rs10752979) in the all blood cell count was satisfied with the Bonferroni corrected P-value (<0.00263). Furthermore, 6 of the 19 SNPs in the PLA2G4A gene showed a weak or moderate association with blood cell count (P-values: 0.0048~0.042), suggesting the clue of an association between the PLA2G4A gene and blood cell count, especially white blood cell count. This study may provide insight into the genetic basis of blood cell count related with reaction of infection.

• Investigative Magnetic Resonance Imaging
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• v.19 no.2
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• pp.114-116
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• 2015

A 21-month-old girl with cri-du-chat syndrome in conjunction with developmental delay underwent brain magnetic resonance imaging (MRI). The MRI showed hypoplasia of the brain stem, a normal cerebellum, thinning of the corpus callosum, and a lack of myelination in both anterior limbs of the internal capsule. She also had neonatal bilateral subependymal cysts. We believe that the symmetrical lack of myelination in both anterior limbs of the internal capsule could be a diagnostic clue of cri-du-chat syndrome.

• Proceedings of the IEEK Conference
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• 2000.07b
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• pp.785-788
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• 2000

The recognition system of a car plate is largely classified as the extraction and recognition of number plate. In this paper, we extract the number plate domain by using a thresholding method as a preprocess step. The computation of the density in a given mask provides a clue of a candidate domain whose density ratio corresponds to the properties of the number plate obtained in the best condition. The contour of the number plate for the recognition of the texts of number plate is extracted by operating Kohonen Algorithm in a localized region. The algorithm reduces noises around the contour. The recognition system with the density computation and Kohonen Algorithm shows a high performance in the real system in connection with a car number plate.