• Title/Summary/Keyword: CLEARANCE

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The Expression of ECP in the Perennial Allergic Rhinitis and Correlations with Mucociliary Clearance (통년성 알레르기성 비염에서의 ECP의 발현양상과 점액섬모수송기간과의 관계)

  • 오승철;김찬우;이상학
    • Korean Journal of Bronchoesophagology
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    • v.4 no.1
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    • pp.85-90
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    • 1998
  • The role of the ECP(Eosinophilic cationic protein) is still unknown in the allergic rhinitis. In bronchial asthma, ECP can induce the exposure of the neuropeptidergic nerve to environments destroying the bronchial mucosa, aggravating the bronchial hypersensitivity and delay the mucociliary clearance. In the clinical aspect, we can (md that patients with perennial allergic rhinitis sometimes have sinusitis. The purpose of this article is to evaluate whether mucosal damage by ECP can play a role to develop the sinusitis by delaying the mucociliary clearance, and relationship between long symptom duration of allergic rhinitis and mucociliary clearance. In 32 perennial allergic rhinitis patients, we elucidated there is correlation among ECP presence, mucociliary clearance, sinusitis, and symptom durations. The obtained results were as follows : 1. ECP appeared in all mucosa of each specimen. 2. Mean mucociliary clearance time is 6 mins. 12 sec. in allergic patients with sinusitis, 6 mins. 36 sec in allergic patients without sinusitis. 3. n out of 32 cases have mucosal destruction. 4. Symptom duration is not correlated with the development of sinusitis. This study suggests that ECP may destroy the mucosa in allergic rhinitis and the mucociliary clearance of allergic rhinitis is not related to sinusitis and symptom dotation. Therefore development of sinusitis in allergic rhinitis seems not to be caused by delaying of mucociliary clearance due to mucosal destruction, but by some other factors.

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Combination Therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for the Treatment of Verruca Plana (곽향정기산가미방(藿香正氣散加味方) 투여 및 소장정격(小腸正格) 시술을 이용한 편평사마귀의 치료 효과)

  • Yun, Jeong-Min;Shin, Sang-Ho;Yoon, Hwa-Jung;Ko, Woo-Shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.23 no.1
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    • pp.169-181
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    • 2010
  • Objective : The purpose of this study was to investigate the effects of Combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok on patients with verucca plana. Methods : Sixty-five patients(male 19, female 46) with verruca plana were treated with Gwakhyangjeonggisangamibang and Sojangjeonggyeok for at least 3 months. After treatment, a clearance rate was divided into 4 scales such as; complete clearance / partial clearance-good / partial clearance-poor / no change. Statistical analysis was performed by using Independent-sample t-test. Results : Mean age of patients was 30.3 and mean period of disease duration was 64.6 months. Fifty-eight patients(73.8%) showed complete clearance, nine(13.8%) partial clearance-good, and eight(12.3%) partial clearance-poor. Complete clearance group(CC group) was statistically younger than failure group and disease duration of CC group was shorter than failure group. Although treatment period of failure group was statistically longer than CC group and dosage(貼) of herbal medicine of failure group was more than CC group, failure group showed partial clearance. Conclusion : This data demonstrates that combination therapy with Gwakhyangjeonggisangamibang and Sojangjeonggyeok could be an effective and safe treatment for the verucca plana.

Numerical Upwelling Experiment for Optimum Arrangement of Artificial Seamount (용승을 고려한 인공해중산 최적배치 수치실험)

  • Kim, Seong-Hyeon;Kim, Dong-Sun
    • Journal of Environmental Science International
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    • v.20 no.8
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    • pp.997-1009
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    • 2011
  • In order to estimate volume transport by upwelling for single artificial seamount, same shape and size of artificial seamount already deployed was applied to numerical experiment. The result showed that strong upwelling appeared at front while took place downwelling at rear. The strongest upwelling existed at the top of the artificial seamount. Volume transport by upwelling was computed as 785 m3/s. Column arrangement was applied to two artificial seamount in three cases; case 1) no clearance, case 2) sixty-five meters of clearance as half of artificial seamount's length, and case 3) hundred-thirty meters of clearance as an artificial seamount's length. All cases of column arrangements showed more upwelling volume transport than that of single seamount. Particularly, the case of no clearance calculated as 106% and appeared the most upwelling effect comparing to two other cases. Row arrangement was also applied to two artificial seamount in three cases; case 4) no clearance, case 5) forty meters of clearance as an artificial seamount's width, and case 6) eighty meters of clearance as twice of artificial seamount's width. Upwelling volume transport in case 4 increased 48% than the case of single seamount. Other two cases of 5 and 6 were estimated as 97% increased and more effective than case 4. According to the case experiments, column arrangements show more upwelling volume transport than that of row arrangements. In cases of column arrangements, with decreasing clearance between two seamount, the effect increases while showing maximum value at clearance zero. In cases of row arrangements, on the contrary, with decreasing clearance between two seamount, the effect decreases while showing minimum value at clearance zero. Since simple barotropic condition was considered for this study, further study is necessary by considering baroclinic condition to get close to reality. In conclusion, in deploying artificial seamount, optimal arrangement should be well designed to enhance primary and secondary productivity and to increase the diversity of species as well as reducing time and space.

The Comparison with Salivary Image and Saliva Clearance Rate in Salivary Scintigraphy (타액선 신티그라피 검사에서 타액선 영상과 타액 제거율의 비교 연구)

  • Kim, Young-Bin;Shin, Kyu-Seol;Park, Yeon-Kyung;Kim, Keon-Jae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.1
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    • pp.15-19
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    • 2009
  • Purpose: The aim of study is to find a correlation between Salivary clearance rate using saliva and blood and Secretion rate and Excretion rate using Salivary gland Scan images. Materials and Methods: Salivary Scan and Stimulate clearance of $^{99m}Tc$-pertechnate was performed in 20 patients with moderate function(group 1), 9 patients with severe function glands (group 2), 3 patients with non function (group 3) and normal 6 controls. Salivay clearance rate was compare with Secretion rate and Excretion rate of Salivary glands' ROI. Result: Stimulate salivary clearance of normal controls was 18.4 ml/min, salivary clearance of group 1 was 10.1 ml/min, salivary clearance of group 2 was 10.4 ml/min and salivary clearance of group 3 was 2.3 ml/min. Significant difference was found between normal controls and group 2,3 (p<0.05, p<0.05). Secretion rate and Excretion rate of normal controls was 21.6%, 24.6%, Secretion rate and Excretion rate of group 1 was 17.6%, 24.0%, Secretion rate and Excretion rate of group 2 was 8.8%, 13.9% and Secretion rate and Excretion rate of group 3 was 5.6%, 2.9%. Significant difference was found between normal controls and group 2,3 (p<0.05, p<0.05). Conclusions: Stimulate salivary clearance using saliva and blood and Secretion rate and Excretion rate using Salivary gland Scan images accord well together.

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Numerical investigations of tip clearance flow characteristics of a pumpjet propulsor

  • Lu, Lin;Gao, Yuefei;Li, Qiang;Du, Lin
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.10 no.3
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    • pp.307-317
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    • 2018
  • In this study, numerical investigations of the tip clearance flow characteristics of a pumpjet propulsor based on Computational Fluid Dynamics (CFD) method have been presented. The Zwart-Gerber-Belamri (Z-G-B) cavitation model based on Reynolds Averaged Navier-Stokes (RANS) method is employed. The structured gird is applied. The formation and development of the tip clearance flows has been investigated and presented. The structure of the tip leakage vortex has been shown. The radial distributions of different velocity components with different Span along the axial direction have been carried out to present the influence of the tip clearance flow on the main flow. In addition, the influences of the tip clearance size on the pumpjet propulsor performance, including the impact on the velocity flow fields and the cavitation characteristic, have been presented.

Numerical Study on Flow Characteristics at Blade Passage and Tip Clearance in a Linear Cascade of High Performance Turbine Blade

  • Myong, Hyon-Kook;Yang, Seung-Yong
    • Journal of Mechanical Science and Technology
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    • v.17 no.4
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    • pp.606-616
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    • 2003
  • A numerical analysis has been conducted in order to simulate the characteristics of complex flow through linear cascades of high performance turbine blade with/without tip clearance by using a pressure-correction based, generalized 3D incompressible Wavier-Stokes CFD code. The development and generation of horseshoe vortex, passage vortex, leakage vortex, tip vortex within tip clearance, etc. are clearly identified through the present simulation which uses the RNG k-$\varepsilon$ turbulent model with wall function method and a second-order linear upwind scheme for convective terms. The present simulation results are consistent with the generally known tendency that occurs in the blade passage and tip clearance. A 3D model for secondary and leakage flows through turbine cascades with/without tip clearance is also suggested from the present simulation results, including the effects of tip clearance height.

An Empirical on The Customs Loyalty in Trust Dimension of Clearance EDI Service (통관 EDI 서비스에서 신뢰차원이 신고인의 세관 충성도에 미치는 실증분석)

  • Lee, Je-Hong
    • International Commerce and Information Review
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    • v.8 no.3
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    • pp.143-164
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    • 2006
  • EDI is fast becoming the standard way of exchanging business documents, not only in this country but throughout the world. The purpose of EDI is currently being used for all the most common business transactions such as purchase orders, invoice, quotes, bill of lading, status reports, receiving advices; and also for some very specific transaction. Thus, the purpose of this study, by way of literature survey and survey research are to find the effectiveness in EDI Service of Clearance Physical. The model of the Trust Dimension and EDI Provider Loyalty in EDI Service of Clearance Physical is tested here using data from 163 samples. Based on the research model, a comprehensive set of hypotheses is formulated and a methodology for testing them is outlined. some of the hypotheses are tested empirically to demonstrate the applicability of the theoretical model. In examining the relationships of the Clearance EDI determinants factors, Trust and e-loyalty show in significantly by customs practice trust, clearance EDI, EDI provider trust and clearance EDI loyalty. but that show in not significantly by a list of names, EDI benevolence.

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Machining Characteristics in High Speed Endmill Operation considering Clearance angle (고속용 엔드밀 가공 시 여유각을 고려한 가공특성)

  • 고성림;박정남;김경배;서천석
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.10a
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    • pp.22-25
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    • 2002
  • The objective of this research is to investigate the effect of clearance angle on cutting performance in high speed endmilling. The tool geometry parameters and cutting process have complex relationship. In order to explain the effect of clearance angle and exist the optimal clearance angle according to the diameter, Using various tool with different clearance angle, numerous cutting tests (cutting force, surface accuracy, too life) was undertaken to show the relationship between clearance angle and cutting process.

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Enhanced Virus Removal by Flocculation and Microfiltration

  • Han Binbing;Carlson Jonathan O.;Powers Scott M.;Wickramasinghe S. Ranil
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.7 no.1
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    • pp.6-9
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    • 2002
  • In this work we have investigated the feasibility of virus clearance by flocculation and tangential flow microfiltration. Chinese hamster ovary cell feed streams were spiked with minute virus of mice and then flocculated using cationic polyelectrolytes prior to tangential flow microfiltration. Our results indicate that flocculation prior to microfiltration leads to more than 100 fold clearance of minute virus of mice particles in the permeate. Today, validation of virus clearance is a major concern in the manufacture of biopharmaceutical products. Frequently new unit operations are added simply to validate virus clearance thus increasing the manufacturing cost. The results obtained here suggest that virus clearance can be obtained during tangential flow microfiltration. Since tangential flow microfiltration is frequently used for bioreactor harvesting this could be a low cost method to validate virus clearance.

Finite Element Analysis on Effect of Die Clearance on Shear Planes in Fine Blanking (파인 블랭킹에서 전단면에 미치는 다이 틈새의 영향에 관한 유한 요소 해석)

  • 김윤주;곽태수;배원병
    • Transactions of Materials Processing
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    • v.9 no.2
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    • pp.152-158
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    • 2000
  • A finite element analysis has been performed to investigate the effect of die clearance on shear planes in the fine blanking of a part of automobile safety belt. For the analysis, S45C is selected as an material, which is used in manufacturing the part of automobile safety belt, and Cockcroft-Latham fracture criterion is applied. Effect of die Clearance on die-roll width, die-roll depth, burnish zone, and fracture zone has been investigated in the finite element analysis by a rigid-plastic FEM code, DEFORM-2D. From the analysis, it has been found that die-roll depth and depth of the shear plane increase with increasing die clearance. And the burnish zone decreases with increasing die clearance, but the variation of fracture zone is opposite to that of burnish zone because the increase in die clearance requires less fracture energy. Theoretical predictions are compared with experimental results. There is a good agreement between theory and experiment.

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